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The map label for this gene is arsA

Identifier: 41408903

GI number: 41408903

Start: 3135643

End: 3136932

Strand: Direct

Name: arsA

Synonym: MAP2805

Alternate gene names: 41408903

Gene position: 3135643-3136932 (Clockwise)

Preceding gene: 41408902

Following gene: 41408906

Centisome position: 64.92

GC content: 66.67

Gene sequence:

>1290_bases
ATGAGCGTCATCGCGATTGCGGTGTTCGTGGTGGCCTACGCCCTGATCGCCAGCGATCGCGTCAACAAGACGTTCGTCGC
GCTGGCCGGCGCCGCGGTGGTCATCACGTTGCCGATGATCCGTTCGGACGACGTCTTCTACTCGCGCGAGACCGGAATCG
ATTGGGACGTAATCTTTTTGCTGCTCGGCATGATGATCATCGTCAGCGTGCTGCGCCAAACCGGTGTCTTCGAGTATGTC
GCGATCTGGTCGGCCAAGCGGGCCCGGGGTTCCCCGCTGCGCGTCATGATCCTGCTGGTGCTGGTGACCGCGCTCGCGTC
GGCCCTGCTGGACAACGTGACCACGGTGTTGCTGATCGCCCCGGTGACCCTGCTGGTGTGCGATCGCCTGGCGATCACCG
CGGCCCCGTTCCTGATGGCCGAGGTGTTCGCGTCGAACGTCGGCGGCGCGGCGACGTTGGTCGGCGACCCGCCCAACATC
ATCATCGCCAGCAGGGGCGGGCTGAGTTTCAACGACTTCCTGGTTCATCTGGCTCCCATCGTGGTCATCGTCGTCGGCGT
GCTGATTGCGTTGCTGCCCAGGCTTTTTCCCGGAGCCTTCACCGTCGATCCCGAGCGGGTGGCCGACGTGATGTCGCTGG
AGGAAAAGGAGGCCATCCGCGATCCCCGGTTGCTGGTCACCTGCGGGGTGGTCTTGCTGGCGGTGTTCGCGGCGTTCATC
GCCCACGGGCCGCTGCACCTGGAACCCTCGCTGGTGGCACTGTTGGGCGCCGGCATCCTGGTGGTGGCGTCGCGGTTGCA
GCCCGCCGACTACCTGTCCGGCGTGGAGTGGGACACGCTGCTGTTTTTCGCCGGCCTGTTCGTCATGGTCGGCGCCCTGG
TGAAGACCGGCGTCGTCAAACACCTTGCCCGCCTGGCGATCACCGCCACCGGCGGCAACACCCTGACCGCGACGATGGTC
ATCCTCGTCGCGTCGGTCGTCATCAGCGGGATCGTCGACAACGTCCCGTACGCCGCGACGATGGCGCCGGTGGTCGCCGA
CCTGGTGCCGGCCCTGGGCGATCACGCCAACCCCGCGGTGTTGTGGTGGTCGCTGGCGCTGGGCACGGACTTCGGCGGCA
ACCTCACCGCGATCGGCGCCAGCGCCAACATCGTGCTGCTCGGGATCGCCCGCCGGGCCGACAATCCGATCTCCTTCTGG
GAGTTCACCCGCAAGGGCGTGGTGGTCACCGCGGTCTCGGTCGCGCTGTCCGCGCTGTATCTGTGGCTGCGCTATTTCGT
GTGGGGCTGA

Upstream 100 bases:

>100_bases
CCGCTCGTCGCGGTGGTCAAGGACGGCCGGCTGATCGGGGTGATCACCGCATCGCGGGTGCTCGGGGCGGCGCTGCGGCC
TTGAATCGGGTGGGACATAG

Downstream 100 bases:

>100_bases
TTCGGCGTCGAGCGTGGGGCCTGGGTACGAACCTCGTTCGTTTTTCGTCCATACCCCCCACGCTCGGCGAGTGCGAAACT
CACCGCGTCAGCAGCGCGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSVIAIAVFVVAYALIASDRVNKTFVALAGAAVVITLPMIRSDDVFYSRETGIDWDVIFLLLGMMIIVSVLRQTGVFEYV
AIWSAKRARGSPLRVMILLVLVTALASALLDNVTTVLLIAPVTLLVCDRLAITAAPFLMAEVFASNVGGAATLVGDPPNI
IIASRGGLSFNDFLVHLAPIVVIVVGVLIALLPRLFPGAFTVDPERVADVMSLEEKEAIRDPRLLVTCGVVLLAVFAAFI
AHGPLHLEPSLVALLGAGILVVASRLQPADYLSGVEWDTLLFFAGLFVMVGALVKTGVVKHLARLAITATGGNTLTATMV
ILVASVVISGIVDNVPYAATMAPVVADLVPALGDHANPAVLWWSLALGTDFGGNLTAIGASANIVLLGIARRADNPISFW
EFTRKGVVVTAVSVALSALYLWLRYFVWG

Sequences:

>Translated_429_residues
MSVIAIAVFVVAYALIASDRVNKTFVALAGAAVVITLPMIRSDDVFYSRETGIDWDVIFLLLGMMIIVSVLRQTGVFEYV
AIWSAKRARGSPLRVMILLVLVTALASALLDNVTTVLLIAPVTLLVCDRLAITAAPFLMAEVFASNVGGAATLVGDPPNI
IIASRGGLSFNDFLVHLAPIVVIVVGVLIALLPRLFPGAFTVDPERVADVMSLEEKEAIRDPRLLVTCGVVLLAVFAAFI
AHGPLHLEPSLVALLGAGILVVASRLQPADYLSGVEWDTLLFFAGLFVMVGALVKTGVVKHLARLAITATGGNTLTATMV
ILVASVVISGIVDNVPYAATMAPVVADLVPALGDHANPAVLWWSLALGTDFGGNLTAIGASANIVLLGIARRADNPISFW
EFTRKGVVVTAVSVALSALYLWLRYFVWG
>Mature_428_residues
SVIAIAVFVVAYALIASDRVNKTFVALAGAAVVITLPMIRSDDVFYSRETGIDWDVIFLLLGMMIIVSVLRQTGVFEYVA
IWSAKRARGSPLRVMILLVLVTALASALLDNVTTVLLIAPVTLLVCDRLAITAAPFLMAEVFASNVGGAATLVGDPPNII
IASRGGLSFNDFLVHLAPIVVIVVGVLIALLPRLFPGAFTVDPERVADVMSLEEKEAIRDPRLLVTCGVVLLAVFAAFIA
HGPLHLEPSLVALLGAGILVVASRLQPADYLSGVEWDTLLFFAGLFVMVGALVKTGVVKHLARLAITATGGNTLTATMVI
LVASVVISGIVDNVPYAATMAPVVADLVPALGDHANPAVLWWSLALGTDFGGNLTAIGASANIVLLGIARRADNPISFWE
FTRKGVVVTAVSVALSALYLWLRYFVWG

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=215, Percent_Identity=35.3488372093023, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1787039, Length=364, Percent_Identity=25.2747252747253, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082277, Length=384, Percent_Identity=26.3020833333333, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550608, Length=482, Percent_Identity=31.1203319502075, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI85724998, Length=468, Percent_Identity=25.8547008547009, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI62484377, Length=468, Percent_Identity=25.6410256410256, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24581759, Length=189, Percent_Identity=39.6825396825397, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28574683, Length=189, Percent_Identity=39.6825396825397, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28574681, Length=189, Percent_Identity=39.6825396825397, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28574685, Length=189, Percent_Identity=39.6825396825397, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28574678, Length=189, Percent_Identity=39.6825396825397, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19920704, Length=189, Percent_Identity=39.6825396825397, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI221472711, Length=222, Percent_Identity=30.1801801801802, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24581764, Length=222, Percent_Identity=30.1801801801802, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24656008, Length=467, Percent_Identity=23.1263383297645, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 45287; Mature: 45156

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIAIAVFVVAYALIASDRVNKTFVALAGAAVVITLPMIRSDDVFYSRETGIDWDVIFL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCCCCCCCEEECCCCCCHHHHHH
LLGMMIIVSVLRQTGVFEYVAIWSAKRARGSPLRVMILLVLVTALASALLDNVTTVLLIA
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVTLLVCDRLAITAAPFLMAEVFASNVGGAATLVGDPPNIIIASRGGLSFNDFLVHLAPI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCHHHHHHHHHHH
VVIVVGVLIALLPRLFPGAFTVDPERVADVMSLEEKEAIRDPRLLVTCGVVLLAVFAAFI
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AHGPLHLEPSLVALLGAGILVVASRLQPADYLSGVEWDTLLFFAGLFVMVGALVKTGVVK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HLARLAITATGGNTLTATMVILVASVVISGIVDNVPYAATMAPVVADLVPALGDHANPAV
HHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCE
LWWSLALGTDFGGNLTAIGASANIVLLGIARRADNPISFWEFTRKGVVVTAVSVALSALY
EEEEHHHCCCCCCCEEEECCCCCEEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHH
LWLRYFVWG
HHHHHHHCC
>Mature Secondary Structure 
SVIAIAVFVVAYALIASDRVNKTFVALAGAAVVITLPMIRSDDVFYSRETGIDWDVIFL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCEEEEEECCCCCCCCEEECCCCCCHHHHHH
LLGMMIIVSVLRQTGVFEYVAIWSAKRARGSPLRVMILLVLVTALASALLDNVTTVLLIA
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVTLLVCDRLAITAAPFLMAEVFASNVGGAATLVGDPPNIIIASRGGLSFNDFLVHLAPI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCHHHHHHHHHHH
VVIVVGVLIALLPRLFPGAFTVDPERVADVMSLEEKEAIRDPRLLVTCGVVLLAVFAAFI
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AHGPLHLEPSLVALLGAGILVVASRLQPADYLSGVEWDTLLFFAGLFVMVGALVKTGVVK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HLARLAITATGGNTLTATMVILVASVVISGIVDNVPYAATMAPVVADLVPALGDHANPAV
HHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCE
LWWSLALGTDFGGNLTAIGASANIVLLGIARRADNPISFWEFTRKGVVVTAVSVALSALY
EEEEHHHCCCCCCCEEEECCCCCEEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHHH
LWLRYFVWG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]