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The map label for this gene is 41408813

Identifier: 41408813

GI number: 41408813

Start: 3050515

End: 3051099

Strand: Reverse

Name: 41408813

Synonym: MAP2715c

Alternate gene names: NA

Gene position: 3051099-3050515 (Counterclockwise)

Preceding gene: 41408814

Following gene: 41408812

Centisome position: 63.17

GC content: 66.67

Gene sequence:

>585_bases
GTGAGTGATCCCGAACAGGCCGAGCAGGACGCCGAGCGCACCATCCTGGACCGCGGTGTCGGCGAGCAGGACCACCTGCA
GCGGTTGTGGACGCCGTACCGGATGACCTATCTGGCCGAGGCGCCGATGAAGCGCGGACCCAACTCGTCGGGCAAGAGCG
AGCAGCCGTTCACCGACATTCCGCAGCTGACCGACGAGGACGGCCTGGTGGTCGCGCGCGGCGAACTGGTCTACGCCGTG
CTCAACCTCTACCCCTACAACCCGGGGCATCTGATGGTGGTGCCCTACCGGCGGGTCTCCGAGCTCGAGGACCTGACCGA
CGCGGAGAGCGCGGAGCTGATGTCGTTCATACAGAAGGCGATTCGCGTCATCAAGAACGTGTCACGCCCGCACGGGTTCA
ACGTCGGCCTGAACCTGGGCACCTCGGCCGGCGGGTCGCTGGCCGAGCATCTGCACGTGCACGTCGTGCCGCGCTGGGGT
GGGGACGCGAACTTCATCACCATCATCGGCGGATCGAAGGTGATCCCGCAGTTGCTGCGCGAAACCCGCCAGCTGCTGGC
CACCGAGTGGGCCAAGCAGTCGTGA

Upstream 100 bases:

>100_bases
AACGGCGTGCCCCGCGACAGCGCGGTCGACGCGATCGTCAAGTGGATCGCCGACCGCGAGAATTCCGTCCCCAGCGCCGA
ACTCGTGAAAGTGTCCAGTG

Downstream 100 bases:

>100_bases
GCCCACACCGCCATGAGTAAGGTGCCGTTTTTGTCCCGCGCGGCGTTCGCGCGGCTGACGACTCCCACCGCCCGGGCCTG
CCTGCGGCTGGGCCTGACCC

Product: hypothetical protein

Products: NA

Alternate protein names: ATP adenylyltransferase; Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase; AP,A phosphorylase [H]

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MSDPEQAEQDAERTILDRGVGEQDHLQRLWTPYRMTYLAEAPMKRGPNSSGKSEQPFTDIPQLTDEDGLVVARGELVYAV
LNLYPYNPGHLMVVPYRRVSELEDLTDAESAELMSFIQKAIRVIKNVSRPHGFNVGLNLGTSAGGSLAEHLHVHVVPRWG
GDANFITIIGGSKVIPQLLRETRQLLATEWAKQS

Sequences:

>Translated_194_residues
MSDPEQAEQDAERTILDRGVGEQDHLQRLWTPYRMTYLAEAPMKRGPNSSGKSEQPFTDIPQLTDEDGLVVARGELVYAV
LNLYPYNPGHLMVVPYRRVSELEDLTDAESAELMSFIQKAIRVIKNVSRPHGFNVGLNLGTSAGGSLAEHLHVHVVPRWG
GDANFITIIGGSKVIPQLLRETRQLLATEWAKQS
>Mature_193_residues
SDPEQAEQDAERTILDRGVGEQDHLQRLWTPYRMTYLAEAPMKRGPNSSGKSEQPFTDIPQLTDEDGLVVARGELVYAVL
NLYPYNPGHLMVVPYRRVSELEDLTDAESAELMSFIQKAIRVIKNVSRPHGFNVGLNLGTSAGGSLAEHLHVHVVPRWGG
DANFITIIGGSKVIPQLLRETRQLLATEWAKQS

Specific function: Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues [H]

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320511, Length=91, Percent_Identity=38.4615384615385, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: =2.7.7.53 [H]

Molecular weight: Translated: 21602; Mature: 21471

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPEQAEQDAERTILDRGVGEQDHLQRLWTPYRMTYLAEAPMKRGPNSSGKSEQPFTDI
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHCHHHCCCCCCCCCCCCCCCC
PQLTDEDGLVVARGELVYAVLNLYPYNPGHLMVVPYRRVSELEDLTDAESAELMSFIQKA
CCCCCCCCEEEECHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHH
IRVIKNVSRPHGFNVGLNLGTSAGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLR
HHHHHHCCCCCCCEEEEECCCCCCCHHHHCEEEEEEECCCCCCCEEEEECCCHHHHHHHH
ETRQLLATEWAKQS
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SDPEQAEQDAERTILDRGVGEQDHLQRLWTPYRMTYLAEAPMKRGPNSSGKSEQPFTDI
CCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHCHHHCCCCCCCCCCCCCCCC
PQLTDEDGLVVARGELVYAVLNLYPYNPGHLMVVPYRRVSELEDLTDAESAELMSFIQKA
CCCCCCCCEEEECHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHH
IRVIKNVSRPHGFNVGLNLGTSAGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLR
HHHHHHCCCCCCCEEEEECCCCCCCHHHHCEEEEEEECCCCCCCEEEEECCCHHHHHHHH
ETRQLLATEWAKQS
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]