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The map label for this gene is 41408811

Identifier: 41408811

GI number: 41408811

Start: 3048902

End: 3049864

Strand: Reverse

Name: 41408811

Synonym: MAP2713c

Alternate gene names: NA

Gene position: 3049864-3048902 (Counterclockwise)

Preceding gene: 41408812

Following gene: 41408810

Centisome position: 63.15

GC content: 73.52

Gene sequence:

>963_bases
GTGATGCCCACCCCGCCGGGGATGAGGGCGATCACCGCGCCGGGCCGGCTGGCCGGCCGGCTGGTGGGCGGCGTCGGCGC
CGACTGGGCGTACGCGACGGGCTGGATGGCGGTGCGGGCGATGCCGGAGTTCGCCGCCCGCAACGCCTTTGACGCCGCCG
CGCGCTACGCGGCCCGCGGCGGCGGCCCCGACCAGCTGCGCAAGAACCTGGCCCGGGTGCTGCGGGTGCCGCCCGCCGAC
GTCCCCGACGCGCTGATGCGGGCCTCGCTGGCCTCCTACGCCCGCTACTGGCGCGAGGCCTTCCGGCTGCCCAGCATGGA
CCTGACCGAGCTGGGCCGCCGGCTACAGGACTCGGTGCGCGGCGAGGACAACCTGGACGCCGCGCTGCGCGCGGGACGCG
GCGCGGTGATCGCGTTGCCGCACAGCGGAAACTGGGACATGGCCGGCGTCTGGCTGGCCCAATCGCACGGCACCTTCACC
ACCGTCGCCGAACGTCTCAAGCCCGAGTCGCTGTACCGGCGGTTCATCGCCTACCGCGAACGGCTCGGGTTCGAGGTGCT
GCCGCTGTCCGGGGGCGAGCGGTCGCCCTTCGAGGTGCTGTGCGACCGGCTGCGGGCCAACCGGGTGGTGTGCCTGATGG
CCGACCGCGACCTGACCCGCACCGGTGTGCAGGTCGACTTCTTCGGCGAGGCCACCCGGATGCCGGCCGGGCCCGCGAAG
CTGGCCATCGCGACCGGCGCGGCGCTGCTGCCGGTGCACGTGCATTTCGAGGGCGAGGGCTGGCGGTTTTTGATCTACCC
GGCGCTGGACTGCAGCAGCGGCGACGTCGGCGCCATCACCCAGGTGCTGGCCGATCACTTCGAGAAGAACATCGCCGCCC
ACCTCGAGGACTGGCACATGATGCAGCCGCAGTGGCTGGCCGACCTCCCCGACTCCACCCGGGCCCGGTTGAGGGACAGC
TGA

Upstream 100 bases:

>100_bases
CGATGTGGGCGCTGGCGGCGGCCAGCCTGGTTACCTGCGCGCAGCGGCTGCACACCGTGCGGACCTCGCCGGGCGCCACC
GACCGAGGATCGGACGCGCC

Downstream 100 bases:

>100_bases
TGCGGATCGGGATGGTCTGCCCCTACTCGTTCGACGTCCCGGGCGGGGTGCAGTCGCACGTCCTGCAGCTGGCCGAGGTG
ATGCGGTGCCGCGGGCACGA

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: PIM acyltransferase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MMPTPPGMRAITAPGRLAGRLVGGVGADWAYATGWMAVRAMPEFAARNAFDAAARYAARGGGPDQLRKNLARVLRVPPAD
VPDALMRASLASYARYWREAFRLPSMDLTELGRRLQDSVRGEDNLDAALRAGRGAVIALPHSGNWDMAGVWLAQSHGTFT
TVAERLKPESLYRRFIAYRERLGFEVLPLSGGERSPFEVLCDRLRANRVVCLMADRDLTRTGVQVDFFGEATRMPAGPAK
LAIATGAALLPVHVHFEGEGWRFLIYPALDCSSGDVGAITQVLADHFEKNIAAHLEDWHMMQPQWLADLPDSTRARLRDS

Sequences:

>Translated_320_residues
MMPTPPGMRAITAPGRLAGRLVGGVGADWAYATGWMAVRAMPEFAARNAFDAAARYAARGGGPDQLRKNLARVLRVPPAD
VPDALMRASLASYARYWREAFRLPSMDLTELGRRLQDSVRGEDNLDAALRAGRGAVIALPHSGNWDMAGVWLAQSHGTFT
TVAERLKPESLYRRFIAYRERLGFEVLPLSGGERSPFEVLCDRLRANRVVCLMADRDLTRTGVQVDFFGEATRMPAGPAK
LAIATGAALLPVHVHFEGEGWRFLIYPALDCSSGDVGAITQVLADHFEKNIAAHLEDWHMMQPQWLADLPDSTRARLRDS
>Mature_320_residues
MMPTPPGMRAITAPGRLAGRLVGGVGADWAYATGWMAVRAMPEFAARNAFDAAARYAARGGGPDQLRKNLARVLRVPPAD
VPDALMRASLASYARYWREAFRLPSMDLTELGRRLQDSVRGEDNLDAALRAGRGAVIALPHSGNWDMAGVWLAQSHGTFT
TVAERLKPESLYRRFIAYRERLGFEVLPLSGGERSPFEVLCDRLRANRVVCLMADRDLTRTGVQVDFFGEATRMPAGPAK
LAIATGAALLPVHVHFEGEGWRFLIYPALDCSSGDVGAITQVLADHFEKNIAAHLEDWHMMQPQWLADLPDSTRARLRDS

Specific function: Catalyzes the acylation to the position 6 of the alpha- 1,2-linked mannose residue of the phosphatidyl-myo-inositol dimannoside (PIM2) or monomannoside (PIM1) [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 35195; Mature: 35195

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPTPPGMRAITAPGRLAGRLVGGVGADWAYATGWMAVRAMPEFAARNAFDAAARYAARG
CCCCCCCCEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
GGPDQLRKNLARVLRVPPADVPDALMRASLASYARYWREAFRLPSMDLTELGRRLQDSVR
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
GEDNLDAALRAGRGAVIALPHSGNWDMAGVWLAQSHGTFTTVAERLKPESLYRRFIAYRE
CCCCHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHH
RLGFEVLPLSGGERSPFEVLCDRLRANRVVCLMADRDLTRTGVQVDFFGEATRMPAGPAK
HCCCEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHCCCEEEECCCCCCCCCCCHH
LAIATGAALLPVHVHFEGEGWRFLIYPALDCSSGDVGAITQVLADHFEKNIAAHLEDWHM
EEEECCCEEEEEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
MQPQWLADLPDSTRARLRDS
CCCHHHHCCCCHHHHHCCCC
>Mature Secondary Structure
MMPTPPGMRAITAPGRLAGRLVGGVGADWAYATGWMAVRAMPEFAARNAFDAAARYAARG
CCCCCCCCEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
GGPDQLRKNLARVLRVPPADVPDALMRASLASYARYWREAFRLPSMDLTELGRRLQDSVR
CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
GEDNLDAALRAGRGAVIALPHSGNWDMAGVWLAQSHGTFTTVAERLKPESLYRRFIAYRE
CCCCHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHH
RLGFEVLPLSGGERSPFEVLCDRLRANRVVCLMADRDLTRTGVQVDFFGEATRMPAGPAK
HCCCEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHCCCEEEECCCCCCCCCCCHH
LAIATGAALLPVHVHFEGEGWRFLIYPALDCSSGDVGAITQVLADHFEKNIAAHLEDWHM
EEEECCCEEEEEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
MQPQWLADLPDSTRARLRDS
CCCHHHHCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]