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The map label for this gene is pimA [H]

Identifier: 41408810

GI number: 41408810

Start: 3047778

End: 3048902

Strand: Reverse

Name: pimA [H]

Synonym: MAP2712c

Alternate gene names: 41408810

Gene position: 3048902-3047778 (Counterclockwise)

Preceding gene: 41408811

Following gene: 41408809

Centisome position: 63.13

GC content: 70.84

Gene sequence:

>1125_bases
ATGCGGATCGGGATGGTCTGCCCCTACTCGTTCGACGTCCCGGGCGGGGTGCAGTCGCACGTCCTGCAGCTGGCCGAGGT
GATGCGGTGCCGCGGGCACGACGTCAGCGTGCTGGCGCCGGCCTCGCCGCACGCCGTGCTGCCCGGCTACGTCGTCTCGG
CGGGTAAGGCCGTCCCGATTCCCTACAACGGCTCGGTGGCCCGGCTGCGGTTCGGCCCGGCCACCCACCGCAAGGTGAAA
AAGTGGCTTGTGGACGGCGATTTCGACGTGCTGCACCTGCACGAGCCCAACGCGCCGAGCCTGTCGATGCTGGCGCTGAA
CATCGCCGAGGGGCCGATCGTGGCGACGTTTCACACCTCGACCACCAAATCGCTGACCCTGACCGTGTTCCAGGGCATCC
TGCGCCCGATGCACGAGAAGATCGTCGGCCGGATCGCGGTCTCCGACCTGGCCCGGCGCTGGCAGATGGAGGCGCTGGGC
ACCGACGCCGTGGAGATCCCCAACGGCGTCGACGTCGCCTCGTTCGCCTCGGCGCCGCGGCTGGACGGTTACCCGCGGGC
CGGCAAGACGGTGCTGTTTTTGGGGCGCTACGACGAGCCGCGCAAGGGCATGGCGGTGCTGCTCGACGCGCTGCCGCGGC
TGGTCGAGCGGTTCGCCGACGTGCAGCTGCTGGTGGTCGGTCGCGGCGACGAGGACCAATTGCGCACGCAGGCAGGCGAA
TTGGTGAAGCACATCCGCTTCCTCGGCCAGGTCGACGACGCCGGCAAGGCGTCGGCCATGCGCAGCGCCGACGTGTACTG
CGCACCCAACCTGGGCGGGGAGAGCTTCGGCATCGTGCTGGTCGAGGCGATGGCCGCCGGCACCCCGGTGGTGGCCAGCG
ACCTGGACGCCTTCCGGCGGGTGCTGCGCGACGGCGAGGTGGGCGCTCTGGTGCCCGTCGGCGACGGCGACGCGCTCGCC
GATGCGCTGATCGCGGTGCTGGAGGATGATGGGCTGCGGGACGGCTACGTGGCCGCGGGGCAGGCGGCCGTCCAGCGCTA
CGACTGGTCGGTGGTGGCCAGCCAGATCATGCGGGTGTACGAGACGGTCGCCGCGACGGGCGCCAAGGTTGAGGTGGCCA
GTTGA

Upstream 100 bases:

>100_bases
AGAAGAACATCGCCGCCCACCTCGAGGACTGGCACATGATGCAGCCGCAGTGGCTGGCCGACCTCCCCGACTCCACCCGG
GCCCGGTTGAGGGACAGCTG

Downstream 100 bases:

>100_bases
TGACATGGCTGATGGTCGGCATCGCGATCCTGGTCGCGGTGCTGGCGGTGGTCGGCGTCTGGGCGTACCGGACCGCCAAT
CGGCTGGACCGGCTGCACGT

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MRIGMVCPYSFDVPGGVQSHVLQLAEVMRCRGHDVSVLAPASPHAVLPGYVVSAGKAVPIPYNGSVARLRFGPATHRKVK
KWLVDGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKSLTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALG
TDAVEIPNGVDVASFASAPRLDGYPRAGKTVLFLGRYDEPRKGMAVLLDALPRLVERFADVQLLVVGRGDEDQLRTQAGE
LVKHIRFLGQVDDAGKASAMRSADVYCAPNLGGESFGIVLVEAMAAGTPVVASDLDAFRRVLRDGEVGALVPVGDGDALA
DALIAVLEDDGLRDGYVAAGQAAVQRYDWSVVASQIMRVYETVAATGAKVEVAS

Sequences:

>Translated_374_residues
MRIGMVCPYSFDVPGGVQSHVLQLAEVMRCRGHDVSVLAPASPHAVLPGYVVSAGKAVPIPYNGSVARLRFGPATHRKVK
KWLVDGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKSLTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALG
TDAVEIPNGVDVASFASAPRLDGYPRAGKTVLFLGRYDEPRKGMAVLLDALPRLVERFADVQLLVVGRGDEDQLRTQAGE
LVKHIRFLGQVDDAGKASAMRSADVYCAPNLGGESFGIVLVEAMAAGTPVVASDLDAFRRVLRDGEVGALVPVGDGDALA
DALIAVLEDDGLRDGYVAAGQAAVQRYDWSVVASQIMRVYETVAATGAKVEVAS
>Mature_374_residues
MRIGMVCPYSFDVPGGVQSHVLQLAEVMRCRGHDVSVLAPASPHAVLPGYVVSAGKAVPIPYNGSVARLRFGPATHRKVK
KWLVDGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTSTTKSLTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALG
TDAVEIPNGVDVASFASAPRLDGYPRAGKTVLFLGRYDEPRKGMAVLLDALPRLVERFADVQLLVVGRGDEDQLRTQAGE
LVKHIRFLGQVDDAGKASAMRSADVYCAPNLGGESFGIVLVEAMAAGTPVVASDLDAFRRVLRDGEVGALVPVGDGDALA
DALIAVLEDDGLRDGYVAAGQAAVQRYDWSVVASQIMRVYETVAATGAKVEVAS

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 39854; Mature: 39854

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGMVCPYSFDVPGGVQSHVLQLAEVMRCRGHDVSVLAPASPHAVLPGYVVSAGKAVPI
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEECCCCEEEC
PYNGSVARLRFGPATHRKVKKWLVDGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTS
CCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEECCCCEEEEEECC
TTKSLTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALGTDAVEIPNGVDVASFASAPR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHCCCCC
LDGYPRAGKTVLFLGRYDEPRKGMAVLLDALPRLVERFADVQLLVVGRGDEDQLRTQAGE
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHH
LVKHIRFLGQVDDAGKASAMRSADVYCAPNLGGESFGIVLVEAMAAGTPVVASDLDAFRR
HHHHHHHHHCCCCCCHHHHHHCCCEEECCCCCCCCHHHHEEEHHHCCCCHHHHHHHHHHH
VLRDGEVGALVPVGDGDALADALIAVLEDDGLRDGYVAAGQAAVQRYDWSVVASQIMRVY
HHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ETVAATGAKVEVAS
HHHHCCCCEEEECC
>Mature Secondary Structure
MRIGMVCPYSFDVPGGVQSHVLQLAEVMRCRGHDVSVLAPASPHAVLPGYVVSAGKAVPI
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEECCCCEEEC
PYNGSVARLRFGPATHRKVKKWLVDGDFDVLHLHEPNAPSLSMLALNIAEGPIVATFHTS
CCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEECCCCEEEEEECC
TTKSLTLTVFQGILRPMHEKIVGRIAVSDLARRWQMEALGTDAVEIPNGVDVASFASAPR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHCCCCC
LDGYPRAGKTVLFLGRYDEPRKGMAVLLDALPRLVERFADVQLLVVGRGDEDQLRTQAGE
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHH
LVKHIRFLGQVDDAGKASAMRSADVYCAPNLGGESFGIVLVEAMAAGTPVVASDLDAFRR
HHHHHHHHHCCCCCCHHHHHHCCCEEECCCCCCCCHHHHEEEHHHCCCCHHHHHHHHHHH
VLRDGEVGALVPVGDGDALADALIAVLEDDGLRDGYVAAGQAAVQRYDWSVVASQIMRVY
HHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ETVAATGAKVEVAS
HHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]