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The map label for this gene is pkn2 [H]

Identifier: 41408770

GI number: 41408770

Start: 3009832

End: 3010503

Strand: Direct

Name: pkn2 [H]

Synonym: MAP2672

Alternate gene names: 41408770

Gene position: 3009832-3010503 (Clockwise)

Preceding gene: 41408767

Following gene: 41408771

Centisome position: 62.32

GC content: 69.79

Gene sequence:

>672_bases
CTGCTCGCGGGCGGGCGGGAAGCGGTCAAGACGGTATGGAACACCGCCAATCTCGTGCGCAAGGAGGGTTTCGGCGCGGC
GGTGCGCAGCTCGATCGAGGAGCTCGCGGACTGGGCCGAGGTGGAGCGGCCCGACCTGGCCCGGGTGACCCCGGACGGCC
GGGTGGTGATCCTGTTCACCGACATCGAGGAATCCACCGCGCTCAACGAGCGGATCGGCGACCGGGCCTGGGTCAAGCTG
ATCAGCTCGCACGACAAGCTGGTCTCGGATCTGGTGCGGCGCCAATCCGGTCACGTGGTGAAGAGCCAGGGCGACGGATT
CATGGTCGCCTTCGCCCGGCCCGAGCAGGCGGTGCGGTGCGGCATCGAGTTGCAGCGCGCGTTGCGCCGGAACGCAAACC
GCAAGCGGCACGAGGAGATTCGGGTCCGGATCGGGATCCACATGGGCCGCTCGGTGCGCCGCGGCGACGACCTGTTCGGC
CGCAACGTCGCGATGGCGGCGCGGGTCGCCGCCCAGGCCGCCGGTGGGGAGATCCTGGTGAGTCAGCCGGTGCGAGACGC
GCTTTCGCGCTCCGACGGGATCCGGTTCGATGACGGACGCGAGGTCGAGCTCAAGGGATTCTCGGGCACCTACCGGTTGT
TCGCCGTGCTGGCCTCGCCCGATCCCGACTGA

Upstream 100 bases:

>100_bases
CGCCGTCGAGGCCGGCGCGCTGGCCGTGCTGTGGCGGCGGCTGGTGCGCAGCCGCGCCGAACTCGACGAGCTGCGTCAGC
GCACCGACGCCCGCAACTGG

Downstream 100 bases:

>100_bases
AGCGCATCGTATTCGGCCAGCCGCTGATGCAAACGATCCCGGACCTCGTCGGCGGTGTAGGCCCGGCGTTTCCGTTGGTC
GCGGACCACCAGCACGCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MLAGGREAVKTVWNTANLVRKEGFGAAVRSSIEELADWAEVERPDLARVTPDGRVVILFTDIEESTALNERIGDRAWVKL
ISSHDKLVSDLVRRQSGHVVKSQGDGFMVAFARPEQAVRCGIELQRALRRNANRKRHEEIRVRIGIHMGRSVRRGDDLFG
RNVAMAARVAAQAAGGEILVSQPVRDALSRSDGIRFDDGREVELKGFSGTYRLFAVLASPDPD

Sequences:

>Translated_223_residues
MLAGGREAVKTVWNTANLVRKEGFGAAVRSSIEELADWAEVERPDLARVTPDGRVVILFTDIEESTALNERIGDRAWVKL
ISSHDKLVSDLVRRQSGHVVKSQGDGFMVAFARPEQAVRCGIELQRALRRNANRKRHEEIRVRIGIHMGRSVRRGDDLFG
RNVAMAARVAAQAAGGEILVSQPVRDALSRSDGIRFDDGREVELKGFSGTYRLFAVLASPDPD
>Mature_223_residues
MLAGGREAVKTVWNTANLVRKEGFGAAVRSSIEELADWAEVERPDLARVTPDGRVVILFTDIEESTALNERIGDRAWVKL
ISSHDKLVSDLVRRQSGHVVKSQGDGFMVAFARPEQAVRCGIELQRALRRNANRKRHEEIRVRIGIHMGRSVRRGDDLFG
RNVAMAARVAAQAAGGEILVSQPVRDALSRSDGIRFDDGREVELKGFSGTYRLFAVLASPDPD

Specific function: Regulates the activity of endogenous beta-lactamase or related enzymes, by blocking their secretion by phosphorylation, in response to an external signal yet to be identified [H]

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271
- InterPro:   IPR002290 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 24656; Mature: 24656

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAGGREAVKTVWNTANLVRKEGFGAAVRSSIEELADWAEVERPDLARVTPDGRVVILFT
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEEE
DIEESTALNERIGDRAWVKLISSHDKLVSDLVRRQSGHVVKSQGDGFMVAFARPEQAVRC
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCHHHHHH
GIELQRALRRNANRKRHEEIRVRIGIHMGRSVRRGDDLFGRNVAMAARVAAQAAGGEILV
HHHHHHHHHHCCCHHHHHHEEEEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHCCCEEEE
SQPVRDALSRSDGIRFDDGREVELKGFSGTYRLFAVLASPDPD
CCHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCC
>Mature Secondary Structure
MLAGGREAVKTVWNTANLVRKEGFGAAVRSSIEELADWAEVERPDLARVTPDGRVVILFT
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEEE
DIEESTALNERIGDRAWVKLISSHDKLVSDLVRRQSGHVVKSQGDGFMVAFARPEQAVRC
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCHHHHHH
GIELQRALRRNANRKRHEEIRVRIGIHMGRSVRRGDDLFGRNVAMAARVAAQAAGGEILV
HHHHHHHHHHCCCHHHHHHEEEEEEEECCCCCCCCCHHHCCHHHHHHHHHHHHCCCEEEE
SQPVRDALSRSDGIRFDDGREVELKGFSGTYRLFAVLASPDPD
CCHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7774814 [H]