Click here to switch to the map view.

The map label for this gene is ephC

Identifier: 41408765

GI number: 41408765

Start: 3004673

End: 3005527

Strand: Reverse

Name: ephC

Synonym: MAP2667c

Alternate gene names: 41408765

Gene position: 3005527-3004673 (Counterclockwise)

Preceding gene: 41408766

Following gene: 41408764

Centisome position: 62.23

GC content: 72.16

Gene sequence:

>855_bases
GTGAAGATGGCTGAACCAGGCTGGATCGACGTGACCGGCCCTGCGGGGGACCTGAAGGCGCTCACCTGGGGGCCGCCCGA
CGGCCCGCTCGCGTTGTGTCTGCACGGCTTCCCCGACACGCCGTACGGGTGGCGCAAGCTCGCTGCCCGGCTCGCCGACG
CGGGGTGGCGGGTGGTCGCGCCCTTCATGCGCGGATACGCGCCGTCGGCGATCCCGTCCGACGGCAGCTACCACGTGGGT
GCGCTGATGGACGACGCGCTGCGGGTGCGCGCGGCCGCCGGCGGTACCGACAACGACGTGGTGATCGGCCACGACTGGGG
GGCGATCGCGGCCACCGGCCTGGCCGCCATGCCCGACAGCCCGTTCGCCAAGGCGGTGCTCATGTCGGTGCCGCCCTCGG
CGGCGTTCCGGCGGCGCGGCGGCAGCGCGGCCGAGCGGGGCCGGCTGGCCGCCCATCTGGCCCGCCAGGTGTTCCGCAGC
TGGTACATCCTGTACTTCCAATTGCCTTGGCTGCCTGAGCGTTCCGCTTCCTGGGTGCTGCCGCTGCTGTGGCGGCGCTG
GTCGCCGGGCTACCGCGCCGAGGAGGATCTGCGGCACGTCGACGCCGCGATCGGGGCGCCGGAGAGCTGGAGGGCGGCGC
TGGGCCCCTACCGCGCCACCATCCGCAACACCGCCCCGCCGGCCCAGTACGCGACGTTGCACCGACTGTGGACCGAGGAG
CCGGTGCTGCCGTGTTTGTACCTTCATGGCCGCGACGACGGTTGCATGACATCGGCTTTCGCTCACCAGGTGGAAAAGGT
GCTGCCCCCCGGCAGCGAAGTCGACATCGTCGAACATGCCGGGCACTTCCTGTAG

Upstream 100 bases:

>100_bases
CCCGCTGACGCAGTGGCGGTTTGACTTCATACTTACTGCGGTCGGTGCGTCTCGACGACACACGGGTTAGGTTGGTCCGT
GCGGACGCGCCGAGCAGGGA

Downstream 100 bases:

>100_bases
CTCGAACAGCCCGACAAGGTCGCCGGCCTGGTGCTCGGGTTCATCGGCTCACCCGGCTGAATGACGGGCCACCGGATGGC
GGCCGTCGATGCGCAGTTCT

Product: EphC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKMAEPGWIDVTGPAGDLKALTWGPPDGPLALCLHGFPDTPYGWRKLAARLADAGWRVVAPFMRGYAPSAIPSDGSYHVG
ALMDDALRVRAAAGGTDNDVVIGHDWGAIAATGLAAMPDSPFAKAVLMSVPPSAAFRRRGGSAAERGRLAAHLARQVFRS
WYILYFQLPWLPERSASWVLPLLWRRWSPGYRAEEDLRHVDAAIGAPESWRAALGPYRATIRNTAPPAQYATLHRLWTEE
PVLPCLYLHGRDDGCMTSAFAHQVEKVLPPGSEVDIVEHAGHFL

Sequences:

>Translated_284_residues
MKMAEPGWIDVTGPAGDLKALTWGPPDGPLALCLHGFPDTPYGWRKLAARLADAGWRVVAPFMRGYAPSAIPSDGSYHVG
ALMDDALRVRAAAGGTDNDVVIGHDWGAIAATGLAAMPDSPFAKAVLMSVPPSAAFRRRGGSAAERGRLAAHLARQVFRS
WYILYFQLPWLPERSASWVLPLLWRRWSPGYRAEEDLRHVDAAIGAPESWRAALGPYRATIRNTAPPAQYATLHRLWTEE
PVLPCLYLHGRDDGCMTSAFAHQVEKVLPPGSEVDIVEHAGHFL
>Mature_284_residues
MKMAEPGWIDVTGPAGDLKALTWGPPDGPLALCLHGFPDTPYGWRKLAARLADAGWRVVAPFMRGYAPSAIPSDGSYHVG
ALMDDALRVRAAAGGTDNDVVIGHDWGAIAATGLAAMPDSPFAKAVLMSVPPSAAFRRRGGSAAERGRLAAHLARQVFRS
WYILYFQLPWLPERSASWVLPLLWRRWSPGYRAEEDLRHVDAAIGAPESWRAALGPYRATIRNTAPPAQYATLHRLWTEE
PVLPCLYLHGRDDGCMTSAFAHQVEKVLPPGSEVDIVEHAGHFL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=290, Percent_Identity=27.9310344827586, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI13376164, Length=290, Percent_Identity=27.9310344827586, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI218777837, Length=272, Percent_Identity=26.8382352941176, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17554012, Length=268, Percent_Identity=25.7462686567164, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 30974; Mature: 30974

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMAEPGWIDVTGPAGDLKALTWGPPDGPLALCLHGFPDTPYGWRKLAARLADAGWRVVA
CCCCCCCEEEEECCCCCCEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEHH
PFMRGYAPSAIPSDGSYHVGALMDDALRVRAAAGGTDNDVVIGHDWGAIAATGLAAMPDS
HHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHCHHCCCCC
PFAKAVLMSVPPSAAFRRRGGSAAERGRLAAHLARQVFRSWYILYFQLPWLPERSASWVL
HHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHH
PLLWRRWSPGYRAEEDLRHVDAAIGAPESWRAALGPYRATIRNTAPPAQYATLHRLWTEE
HHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHCCC
PVLPCLYLHGRDDGCMTSAFAHQVEKVLPPGSEVDIVEHAGHFL
CCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MKMAEPGWIDVTGPAGDLKALTWGPPDGPLALCLHGFPDTPYGWRKLAARLADAGWRVVA
CCCCCCCEEEEECCCCCCEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEHH
PFMRGYAPSAIPSDGSYHVGALMDDALRVRAAAGGTDNDVVIGHDWGAIAATGLAAMPDS
HHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHCHHCCCCC
PFAKAVLMSVPPSAAFRRRGGSAAERGRLAAHLARQVFRSWYILYFQLPWLPERSASWVL
HHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHH
PLLWRRWSPGYRAEEDLRHVDAAIGAPESWRAALGPYRATIRNTAPPAQYATLHRLWTEE
HHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHCCC
PVLPCLYLHGRDDGCMTSAFAHQVEKVLPPGSEVDIVEHAGHFL
CCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]