BacMap

Definition	Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession	NC_002944
Length	4,829,781

Click here to switch to the map view.

The map label for this gene is betB [C]

Identifier: 41408745

GI number: 41408745

Start: 2980911

End: 2981351

Strand: Reverse

Name: betB [C]

Synonym: MAP2647c

Alternate gene names: 41408745

Gene position: 2981351-2980911 (Counterclockwise)

Preceding gene: 41408746

Following gene: 41408744

Centisome position: 61.73

GC content: 66.44

Gene sequence:

>441_bases
ATGGGCTACATCCGCAAGGGGGTCGAAGAGGGCGCCACCGCACTGGTCGGCGGACCCGACGCGCCCACCGGTTTCGACAA
GGGATACTACGTACGGCCAACGCTTTTCACCGACGTCGACAACTCGATGACGATCGCCCAGGAGGAGATCTTCGGACCGG
TGTTGTGCGTCATCCCGTTCGACGACGAGGAGGACGCCATCCGGATCGCCAACGACAGCAAGTACGGCCTGGCCGGCAAC
GTGATGTCGGGCTCGCTGGAGCGCTCGCTTTCGGTGGCGCGCCGGATCCGGGCCGGCTTCATGGGCGTCAACGGCGGCGC
GCCCTACGGCGCCGACACCCCGTTCGGTGGCTACAAGTACAGCGGGGTCGGGCGCCAGAACGGTGTGGCCGGATTCGACC
AGTACACCGAGATCAAGTCGGTCGCCTATCCGGCCGGCTAG

Upstream 100 bases:

>100_bases
CGATCCTCAAGGGCATCTACGAGAACGTCACCTGCGGCGACCCGCAGGACCCCGGGCCCTTTGCGGCCCGGTCATTTCGC
AGGTGCAGCGCGACCGCGTG

Downstream 100 bases:

>100_bases
CGGTCCGATGCCTGGTGCCACGTAAAGCGCTGCCACGCAACGCCTTCGACGATGCGCGCCGGGCTTGGGGCTGACGGCCG
TTGGCGGTCGGGCCGCGCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MGYIRKGVEEGATALVGGPDAPTGFDKGYYVRPTLFTDVDNSMTIAQEEIFGPVLCVIPFDDEEDAIRIANDSKYGLAGN
VMSGSLERSLSVARRIRAGFMGVNGGAPYGADTPFGGYKYSGVGRQNGVAGFDQYTEIKSVAYPAG

Sequences:

>Translated_146_residues
MGYIRKGVEEGATALVGGPDAPTGFDKGYYVRPTLFTDVDNSMTIAQEEIFGPVLCVIPFDDEEDAIRIANDSKYGLAGN
VMSGSLERSLSVARRIRAGFMGVNGGAPYGADTPFGGYKYSGVGRQNGVAGFDQYTEIKSVAYPAG
>Mature_145_residues
GYIRKGVEEGATALVGGPDAPTGFDKGYYVRPTLFTDVDNSMTIAQEEIFGPVLCVIPFDDEEDAIRIANDSKYGLAGNV
MSGSLERSLSVARRIRAGFMGVNGGAPYGADTPFGGYKYSGVGRQNGVAGFDQYTEIKSVAYPAG

Specific function: This Is A Soluble NAD-Dependent Betaine Aldehyde- Specific Dehydrogenase. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777732, Length=141, Percent_Identity=45.3900709219858, Blast_Score=122, Evalue=8e-29,
Organism=Homo sapiens, GI301500698, Length=144, Percent_Identity=39.5833333333333, Blast_Score=114, Evalue=2e-26,
Organism=Homo sapiens, GI25952152, Length=144, Percent_Identity=39.5833333333333, Blast_Score=114, Evalue=3e-26,
Organism=Homo sapiens, GI21361176, Length=142, Percent_Identity=40.8450704225352, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI115387104, Length=150, Percent_Identity=37.3333333333333, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI12007648, Length=143, Percent_Identity=39.8601398601399, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI25777730, Length=141, Percent_Identity=39.7163120567376, Blast_Score=106, Evalue=9e-24,
Organism=Homo sapiens, GI153266822, Length=143, Percent_Identity=38.4615384615385, Blast_Score=104, Evalue=3e-23,
Organism=Homo sapiens, GI25777726, Length=142, Percent_Identity=38.0281690140845, Blast_Score=103, Evalue=7e-23,
Organism=Homo sapiens, GI25777724, Length=142, Percent_Identity=38.0281690140845, Blast_Score=103, Evalue=7e-23,
Organism=Homo sapiens, GI25777728, Length=141, Percent_Identity=37.5886524822695, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI21614513, Length=145, Percent_Identity=38.6206896551724, Blast_Score=101, Evalue=2e-22,
Organism=Homo sapiens, GI238814322, Length=144, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI4507229, Length=140, Percent_Identity=40, Blast_Score=82, Evalue=1e-16,
Organism=Homo sapiens, GI25777721, Length=140, Percent_Identity=40, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI11095441, Length=144, Percent_Identity=32.6388888888889, Blast_Score=68, Evalue=3e-12,
Organism=Homo sapiens, GI73695881, Length=120, Percent_Identity=32.5, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI73695879, Length=120, Percent_Identity=32.5, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI310128095, Length=142, Percent_Identity=32.3943661971831, Blast_Score=64, Evalue=4e-11,
Organism=Homo sapiens, GI310128097, Length=142, Percent_Identity=32.3943661971831, Blast_Score=64, Evalue=4e-11,
Organism=Homo sapiens, GI310128089, Length=142, Percent_Identity=32.3943661971831, Blast_Score=64, Evalue=6e-11,
Organism=Homo sapiens, GI310128091, Length=142, Percent_Identity=32.3943661971831, Blast_Score=63, Evalue=7e-11,
Organism=Homo sapiens, GI310128093, Length=142, Percent_Identity=32.3943661971831, Blast_Score=63, Evalue=8e-11,
Organism=Homo sapiens, GI310128103, Length=142, Percent_Identity=32.3943661971831, Blast_Score=63, Evalue=8e-11,
Organism=Homo sapiens, GI188035924, Length=142, Percent_Identity=32.3943661971831, Blast_Score=63, Evalue=8e-11,
Organism=Escherichia coli, GI1786504, Length=142, Percent_Identity=45.0704225352113, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1787558, Length=142, Percent_Identity=40.1408450704225, Blast_Score=102, Evalue=9e-24,
Organism=Escherichia coli, GI87081896, Length=127, Percent_Identity=40.1574803149606, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082295, Length=143, Percent_Identity=38.4615384615385, Blast_Score=94, Evalue=4e-21,
Organism=Escherichia coli, GI1787715, Length=140, Percent_Identity=37.8571428571429, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI1789015, Length=137, Percent_Identity=35.7664233576642, Blast_Score=87, Evalue=4e-19,
Organism=Escherichia coli, GI1787684, Length=138, Percent_Identity=37.6811594202899, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI87081926, Length=138, Percent_Identity=32.6086956521739, Blast_Score=79, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562198, Length=141, Percent_Identity=47.5177304964539, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32564736, Length=141, Percent_Identity=45.3900709219858, Blast_Score=125, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI25144435, Length=141, Percent_Identity=45.3900709219858, Blast_Score=125, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI25143874, Length=146, Percent_Identity=43.8356164383562, Blast_Score=122, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI25143876, Length=146, Percent_Identity=43.8356164383562, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71995606, Length=142, Percent_Identity=38.0281690140845, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI133930964, Length=141, Percent_Identity=37.5886524822695, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17534119, Length=127, Percent_Identity=38.5826771653543, Blast_Score=92, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17551164, Length=140, Percent_Identity=35.7142857142857, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71995613, Length=85, Percent_Identity=40, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71986308, Length=144, Percent_Identity=31.9444444444444, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323821, Length=140, Percent_Identity=40.7142857142857, Blast_Score=116, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6325196, Length=141, Percent_Identity=42.5531914893617, Blast_Score=113, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323822, Length=140, Percent_Identity=39.2857142857143, Blast_Score=113, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324950, Length=141, Percent_Identity=39.0070921985816, Blast_Score=111, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6320917, Length=141, Percent_Identity=39.0070921985816, Blast_Score=110, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6321828, Length=146, Percent_Identity=32.8767123287671, Blast_Score=82, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319478, Length=109, Percent_Identity=32.1100917431193, Blast_Score=76, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129399, Length=141, Percent_Identity=46.0992907801418, Blast_Score=116, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24650465, Length=141, Percent_Identity=41.8439716312057, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI281362580, Length=142, Percent_Identity=41.5492957746479, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI62472918, Length=142, Percent_Identity=41.5492957746479, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI62472926, Length=142, Percent_Identity=41.5492957746479, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI62472936, Length=142, Percent_Identity=41.5492957746479, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI21356737, Length=142, Percent_Identity=41.5492957746479, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24585660, Length=143, Percent_Identity=38.4615384615385, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638876, Length=145, Percent_Identity=35.8620689655172, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24638878, Length=147, Percent_Identity=34.0136054421769, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45552499, Length=135, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281360303, Length=135, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.3 [H]

Molecular weight: Translated: 15436; Mature: 15305

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYIRKGVEEGATALVGGPDAPTGFDKGYYVRPTLFTDVDNSMTIAQEEIFGPVLCVIPF
CCHHHHHHHCCCEEEECCCCCCCCCCCCEEECCEEEECCCCCEEEHHHHCCCCEEEEEEC
DDEEDAIRIANDSKYGLAGNVMSGSLERSLSVARRIRAGFMGVNGGAPYGADTPFGGYKY
CCCCCEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCEEE
SGVGRQNGVAGFDQYTEIKSVAYPAG
CCCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
GYIRKGVEEGATALVGGPDAPTGFDKGYYVRPTLFTDVDNSMTIAQEEIFGPVLCVIPF
CHHHHHHHCCCEEEECCCCCCCCCCCCEEECCEEEECCCCCEEEHHHHCCCCEEEEEEC
DDEEDAIRIANDSKYGLAGNVMSGSLERSLSVARRIRAGFMGVNGGAPYGADTPFGGYKY
CCCCCEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCEEE
SGVGRQNGVAGFDQYTEIKSVAYPAG
CCCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA