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The map label for this gene is pimE

Identifier: 41408722

GI number: 41408722

Start: 2960453

End: 2961766

Strand: Reverse

Name: pimE

Synonym: MAP2624c

Alternate gene names: 41408722

Gene position: 2961766-2960453 (Counterclockwise)

Preceding gene: 41408725

Following gene: 41408719

Centisome position: 61.32

GC content: 70.7

Gene sequence:

>1314_bases
TTGAAAACGGGCCATCTGGGCACCGAGGCCACGGCCGCGCGCGCCCCGATCGCTAAAGTCGGGCGGATAGACACCACCTC
GGCCGCCCCGGCGGCACCCAGCACCCGGCGTGCGGCGGACGCCCTCGCTGTGGCGGCCCCGCTGCTGCTCGTCGCGAGCG
TCGCCGCGCGCCTGGCCTGGACGTACCTGGTCCCCAACGGCGCGAACTTCGTCGACCTGCACGTCTACCTCGGCGGAGCG
GCCGCGCTCGACCACCCCGGCACGCTGTACAGCTACGTCTACGCCGACCAGACGCCGGACTTCCCGCTGCCGTTCACCTA
TCCGCCGTTCGCGGCCATCGTCTTCTACCCGCTGCACCTGCTGCCGTTCGGCCTGGTGGCCCTGGGTTGGCAACTGGCGA
CCATCGCCGCGCTGTACGGCGCCGTCCGGATCAGCCAGCGCCTGCTGGGCGTGCCGGCCGGCGCCCACGGCCGGCGCGTC
GCGATGGTGTGGACGGCGGTCACCATCTGGATCGAGCCGCTGCGCAGCACCTTCGACTACGGCCAGGTCAACGTGTTGCT
GATGACCGCGGTGCTGTGGGCGGTCTACAGCACGCGATGGTGGCTGTCGGGTCTGCTGGTCGGATTGGCGGCCGGCATCA
AGTTAACTCCCGCGGTCACCGGTGTGTACCTGGCCGGTGCCCGGCGGTGGGCCGCGACGATGTTCTCAGCCGTCATATTC
CTTGCCACCATTGGGATTTCGGTCCTCGTCGTCGGCGACCAGACGCGCTACTACTTCACCGAGCTGCTCGGTGACGCCCA
CCGGGTCGGCCCCATCGCCACCTCGTTCAATCAGTCCTGGCGCGGCGGCCTCTCCCGAATCCTGGGTCACGACGTGGGAT
TCGGCCCGCTGCTGGTGACCGCCGTCGCGGGCACCGCGGTGCTGGCCGTGCTGGCCTGGCGCGCACTCGACCGCTCCGAC
CGGCTGGGCAGGTTGATCGTGGTGGAGGTGTTCGGGCTGCTGCTCTCGCCGATCTCCTGGACACACCACTGGGTGTGGCT
GGTGCCGCTGATGATCTGGGCGATCCACGGCCCGGTGCGCGCCTGGCGCGGCGCGCGCCTCGTGGGGTGGGGTTGGCTGG
CGCTGACCGTCATCGGGGTGCCGTGGTTGTTGAGCTTCGCGCAACCGAACATCTGGCAGATCGGCCGGCCGTGGTATCTG
GCCTGGGCGGGGCTGGTCTACATCGTCGCGGCGGTAGCGACGTTGGTCTGGATCGCGGCCGCCGGCCGCCGCGCCGGTCA
CCAGGTCACCGCGCCGAGCGTCACGCCAGCGTGA

Upstream 100 bases:

>100_bases
GAAGCTACTTTGATGCAGATGGGACTCAAGTGACACGTGTGGCATTTATTTGATCGTTACCGATACGAGCGACAGCGGTG
ACCGGACGCGCGAAAACCGC

Downstream 100 bases:

>100_bases
CCGCCGCCGGCGAGCGTCACGCCAGCGTGACCGCCGCCGGCGCAGGCGAGGGCAGGCGAGGGCTAGCTGCCGACGATGCC
GTTGATGTCGCGCGCCATGT

Product: mannosyltransferase

Products: NA

Alternate protein names: Alpha-mannosyltransferase; Alpha-manT; PPM-dependent mannosyltransferase; Polyprenol-phosphate-mannose alpha-mannosyltransferase; PPM alpha-mannosyltransferase [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MKTGHLGTEATAARAPIAKVGRIDTTSAAPAAPSTRRAADALAVAAPLLLVASVAARLAWTYLVPNGANFVDLHVYLGGA
AALDHPGTLYSYVYADQTPDFPLPFTYPPFAAIVFYPLHLLPFGLVALGWQLATIAALYGAVRISQRLLGVPAGAHGRRV
AMVWTAVTIWIEPLRSTFDYGQVNVLLMTAVLWAVYSTRWWLSGLLVGLAAGIKLTPAVTGVYLAGARRWAATMFSAVIF
LATIGISVLVVGDQTRYYFTELLGDAHRVGPIATSFNQSWRGGLSRILGHDVGFGPLLVTAVAGTAVLAVLAWRALDRSD
RLGRLIVVEVFGLLLSPISWTHHWVWLVPLMIWAIHGPVRAWRGARLVGWGWLALTVIGVPWLLSFAQPNIWQIGRPWYL
AWAGLVYIVAAVATLVWIAAAGRRAGHQVTAPSVTPA

Sequences:

>Translated_437_residues
MKTGHLGTEATAARAPIAKVGRIDTTSAAPAAPSTRRAADALAVAAPLLLVASVAARLAWTYLVPNGANFVDLHVYLGGA
AALDHPGTLYSYVYADQTPDFPLPFTYPPFAAIVFYPLHLLPFGLVALGWQLATIAALYGAVRISQRLLGVPAGAHGRRV
AMVWTAVTIWIEPLRSTFDYGQVNVLLMTAVLWAVYSTRWWLSGLLVGLAAGIKLTPAVTGVYLAGARRWAATMFSAVIF
LATIGISVLVVGDQTRYYFTELLGDAHRVGPIATSFNQSWRGGLSRILGHDVGFGPLLVTAVAGTAVLAVLAWRALDRSD
RLGRLIVVEVFGLLLSPISWTHHWVWLVPLMIWAIHGPVRAWRGARLVGWGWLALTVIGVPWLLSFAQPNIWQIGRPWYL
AWAGLVYIVAAVATLVWIAAAGRRAGHQVTAPSVTPA
>Mature_437_residues
MKTGHLGTEATAARAPIAKVGRIDTTSAAPAAPSTRRAADALAVAAPLLLVASVAARLAWTYLVPNGANFVDLHVYLGGA
AALDHPGTLYSYVYADQTPDFPLPFTYPPFAAIVFYPLHLLPFGLVALGWQLATIAALYGAVRISQRLLGVPAGAHGRRV
AMVWTAVTIWIEPLRSTFDYGQVNVLLMTAVLWAVYSTRWWLSGLLVGLAAGIKLTPAVTGVYLAGARRWAATMFSAVIF
LATIGISVLVVGDQTRYYFTELLGDAHRVGPIATSFNQSWRGGLSRILGHDVGFGPLLVTAVAGTAVLAVLAWRALDRSD
RLGRLIVVEVFGLLLSPISWTHHWVWLVPLMIWAIHGPVRAWRGARLVGWGWLALTVIGVPWLLSFAQPNIWQIGRPWYL
AWAGLVYIVAAVATLVWIAAAGRRAGHQVTAPSVTPA

Specific function: Catalyzes the alpha-1,2 addition of a mannose residue from polyprenol-phosphate-mannose (PPM) to a monoacyl phosphatidylinositol pentamannoside (AcPIM5) to generate a monoacyl phosphatidylinositol hexamannoside (AcPIM6) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PIGM family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018584 [H]

Pfam domain/function: PF09594 DUF2029 [H]

EC number: NA

Molecular weight: Translated: 46993; Mature: 46993

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGHLGTEATAARAPIAKVGRIDTTSAAPAAPSTRRAADALAVAAPLLLVASVAARLAW
CCCCCCCCCCHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHE
TYLVPNGANFVDLHVYLGGAAALDHPGTLYSYVYADQTPDFPLPFTYPPFAAIVFYPLHL
EEECCCCCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
LPFGLVALGWQLATIAALYGAVRISQRLLGVPAGAHGRRVAMVWTAVTIWIEPLRSTFDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCC
GQVNVLLMTAVLWAVYSTRWWLSGLLVGLAAGIKLTPAVTGVYLAGARRWAATMFSAVIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
LATIGISVLVVGDQTRYYFTELLGDAHRVGPIATSFNQSWRGGLSRILGHDVGFGPLLVT
HHHHCEEEEEECCCHHHHHHHHHCCHHHCCCHHHHCCHHHHHHHHHHHHCCCCHHHHHHH
AVAGTAVLAVLAWRALDRSDRLGRLIVVEVFGLLLSPISWTHHWVWLVPLMIWAIHGPVR
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHH
AWRGARLVGWGWLALTVIGVPWLLSFAQPNIWQIGRPWYLAWAGLVYIVAAVATLVWIAA
HHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHH
AGRRAGHQVTAPSVTPA
HCCCCCCEECCCCCCCC
>Mature Secondary Structure
MKTGHLGTEATAARAPIAKVGRIDTTSAAPAAPSTRRAADALAVAAPLLLVASVAARLAW
CCCCCCCCCCHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHE
TYLVPNGANFVDLHVYLGGAAALDHPGTLYSYVYADQTPDFPLPFTYPPFAAIVFYPLHL
EEECCCCCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
LPFGLVALGWQLATIAALYGAVRISQRLLGVPAGAHGRRVAMVWTAVTIWIEPLRSTFDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCC
GQVNVLLMTAVLWAVYSTRWWLSGLLVGLAAGIKLTPAVTGVYLAGARRWAATMFSAVIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHHHHHHHHH
LATIGISVLVVGDQTRYYFTELLGDAHRVGPIATSFNQSWRGGLSRILGHDVGFGPLLVT
HHHHCEEEEEECCCHHHHHHHHHCCHHHCCCHHHHCCHHHHHHHHHHHHCCCCHHHHHHH
AVAGTAVLAVLAWRALDRSDRLGRLIVVEVFGLLLSPISWTHHWVWLVPLMIWAIHGPVR
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHH
AWRGARLVGWGWLALTVIGVPWLLSFAQPNIWQIGRPWYLAWAGLVYIVAAVATLVWIAA
HHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHH
AGRRAGHQVTAPSVTPA
HCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]