Click here to switch to the map view.

The map label for this gene is nudF [C]

Identifier: 41408575

GI number: 41408575

Start: 2781271

End: 2781897

Strand: Reverse

Name: nudF [C]

Synonym: MAP2477c

Alternate gene names: 41408575

Gene position: 2781897-2781271 (Counterclockwise)

Preceding gene: 41408578

Following gene: 41408572

Centisome position: 57.6

GC content: 68.9

Gene sequence:

>627_bases
ATCGGGACGCTACTCCTGGCCGTGTCGGGTGTGGTGTTCGTCGCGATACTGGGCGGCGTGACTTTCATCGAACGCCTCGC
CAGCCGGGAGATCTACCGCAACCCGTGGATGGTGTTGCGCGAGGACGACATCCGCCGCCCGGACGGCAGCGCGGGCATCT
ACAGCGTGGTCGACAAGCCTTCGTACGCGCTGGTGATGCCCTACGACGGGCGGCGTTTCGGGTTGGTGGAGCAGTTTCGC
TACCCGATCGGGGAGCGGCGCTGGGAGTTCCCCCAGGGCACCGCTCCGGAGTTGGCCGACGCCGATCCCGTCGAGCTGGC
CCGGCGTGAGCTGCGCGAGGAAACCGGATTGCGCGCAACGACGTTCGAGCCGCTGGGCCGGCTCGACGTGGCCCCGGGGA
TGAGCAGTCAGCGCGGCTGGGTGTTCCTGGCCACCGGGATCGTCGAGGGTGAAGCCGACCGCGAGCACGAGGAGCAGGAC
ATGCGCAGCGCCTGGTTCTCCCGCGACGACGTCGAGCAGATGATCCGGACGGGCGTCATCGCCGACGCGCAGTCGATCGC
CGCGTACGGCCTGTTCCTGTTGCGCCCGGAATCAACCGGCGCGCCCGTGACGGATCAGGGGCAGTAG

Upstream 100 bases:

>100_bases
TCGGCCGCGTACAGGGTCACGATGTCGTCGGCGGTACCGGTGGCGACGAGCGCCAGGTAGCGATTCACGGTGTCGGTGAT
GGCTTCTGCGGACGGCATGA

Downstream 100 bases:

>100_bases
TTGGATTCCGCGGCGCTGACGATGGCCGTGGCGTCTGCGTAGTTGAAGGAACTGTTCAGGCCGGAATGCACATCGGCGGC
CAGCTCGTCCGGGGTTTTGC

Product: hypothetical protein

Products: AMP; D-Ribose 5- Phosphate. [C]

Alternate protein names: ADP-Ribose Pyrophosphatase; MutT/Nudix Family Protein; Hydrolase NUDIX Family; Nudix Hydrolase; NUDIX Family Hydrolase; NTP Pyrophosphohydrolase; NTP Pyrophosphohydrolase Including Oxidative Damage Repair; MutT/NUDIX NTP Pyrophosphatase; ADP-Ribose Diphosphatase; NUDIX Hydroxylase; MutT/NUDIX Family Protein; Nudix Hydroxylase; Hydrolase; NTP Pyrophosphohydrolases; Nudix Superfamily Hydrolase; Pyrophosphatase MutT/Nudix Family Protein; Hydrolase MutT; Hydrolase NUDIX Family Domain Protein; Hydrolase Nudix Family Protein; Pyrophosphohydrolase Related Protein; NUDIX Family Protein

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MGTLLLAVSGVVFVAILGGVTFIERLASREIYRNPWMVLREDDIRRPDGSAGIYSVVDKPSYALVMPYDGRRFGLVEQFR
YPIGERRWEFPQGTAPELADADPVELARRELREETGLRATTFEPLGRLDVAPGMSSQRGWVFLATGIVEGEADREHEEQD
MRSAWFSRDDVEQMIRTGVIADAQSIAAYGLFLLRPESTGAPVTDQGQ

Sequences:

>Translated_208_residues
MGTLLLAVSGVVFVAILGGVTFIERLASREIYRNPWMVLREDDIRRPDGSAGIYSVVDKPSYALVMPYDGRRFGLVEQFR
YPIGERRWEFPQGTAPELADADPVELARRELREETGLRATTFEPLGRLDVAPGMSSQRGWVFLATGIVEGEADREHEEQD
MRSAWFSRDDVEQMIRTGVIADAQSIAAYGLFLLRPESTGAPVTDQGQ
>Mature_207_residues
GTLLLAVSGVVFVAILGGVTFIERLASREIYRNPWMVLREDDIRRPDGSAGIYSVVDKPSYALVMPYDGRRFGLVEQFRY
PIGERRWEFPQGTAPELADADPVELARRELREETGLRATTFEPLGRLDVAPGMSSQRGWVFLATGIVEGEADREHEEQDM
RSAWFSRDDVEQMIRTGVIADAQSIAAYGLFLLRPESTGAPVTDQGQ

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process. [C]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.13 [C]

Molecular weight: Translated: 23239; Mature: 23107

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTLLLAVSGVVFVAILGGVTFIERLASREIYRNPWMVLREDDIRRPDGSAGIYSVVDKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCC
SYALVMPYDGRRFGLVEQFRYPIGERRWEFPQGTAPELADADPVELARRELREETGLRAT
CEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEE
TFEPLGRLDVAPGMSSQRGWVFLATGIVEGEADREHEEQDMRSAWFSRDDVEQMIRTGVI
CCCCCCCEECCCCCCCCCCEEEEEECEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCH
ADAQSIAAYGLFLLRPESTGAPVTDQGQ
HCHHHHHHHCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
GTLLLAVSGVVFVAILGGVTFIERLASREIYRNPWMVLREDDIRRPDGSAGIYSVVDKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEECCC
SYALVMPYDGRRFGLVEQFRYPIGERRWEFPQGTAPELADADPVELARRELREETGLRAT
CEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEE
TFEPLGRLDVAPGMSSQRGWVFLATGIVEGEADREHEEQDMRSAWFSRDDVEQMIRTGVI
CCCCCCCEECCCCCCCCCCEEEEEECEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCH
ADAQSIAAYGLFLLRPESTGAPVTDQGQ
HCHHHHHHHCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ADP-Ribose; H2O [C]

Specific reaction: ADP-Ribose + H2O = AMP + D-Ribose 5- Phosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA