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The map label for this gene is lip2 [H]

Identifier: 41408462

GI number: 41408462

Start: 2656902

End: 2657846

Strand: Reverse

Name: lip2 [H]

Synonym: MAP2364c

Alternate gene names: 41408462

Gene position: 2657846-2656902 (Counterclockwise)

Preceding gene: 41408465

Following gene: 41408461

Centisome position: 55.03

GC content: 69.84

Gene sequence:

>945_bases
CTGGCCCGGCCGCAAGGCCTTACCCGCATCGACCCGGCGCTGCGGGACACCGCCGCCCAGTTGGGGGTGGTGGAGTTCCG
CGCCGAAACCCTGGCCGCCGAGCGGGAACACGCCAACCGGTTGGCCGCCCAGCGCGCCGCATCCGCCGACACCCGCGGCG
TGGCGATCGATTCGGTGTCGATCGCCGGGCCGGACGGTCAGCCGCTGGAGCTTCGCTTGTATCGCGGCCACACCGAATCC
GCGGCGCCGCTGCTGGTGTACGCCCACGGCGGCGCGTTCGTCACCGGCAACCTCGCCACCGACCACGCGCACTGCGTGGA
GTTGGCCCGTGACGGCGGGTGTCTGGTGGTGTCGGTCGACTACCGGCTGGCGCCCGAAAATCCCTGTCCCGCGGCGCTGG
ACGACGTCGAAGCCGCCTTCCGGTACGTCGTCGACAACAGCGCGGCGCTGAACGCCGACGCCAACCGCATCGCCGTGATG
GGCCGGGACGCCGGCGCGGCCCTGGTGGCGGGCCTGACCCAGCGCATGTTCGACCAGGAGGGGCCGACGATCCTGATGCA
GATCCTGCACCAGCCGATGCTGGATTCCGACGCCACGCCGTCGCGTCGCGAATTCCAGCGCACGCCGGGTCTGAACGGTC
CGGCCGTGAGCCGGGCCTGGAACCACTACCTCGGTCACGCCAGCGCCAGCGGTCAGCACGTCCCCGCCCACCGGGCCAAC
CTCGAGGGCCTGCCGCCCACGTTCATCAGCTGCTCGGAGATCGATCCGTGCCGCGACGAGGCCATCGACTATGCCAATCG
GCTGCTGCACGCCTACGTGCACACCGAATTGCATGTGATCGCAGCAACCTTCAACGGTTTCGACTCGATGGTCCCGGATT
GGATTGTTGCCCAAGAGAACCGGGCGCTGCACGCGCAGGCGTTACGCCGCGTCTTCGCCATGTAG

Upstream 100 bases:

>100_bases
GGTCTACTTTGAAGGTGGTGTCCGGCACCACCGTCCGCCGGGACCGTCGACGAGCCCGCCGATCAGCCGACGAAAACGAG
TAGGTATGACACAGACGAAC

Downstream 100 bases:

>100_bases
GACGGGCCGGGTGTCTGCCGGCGGCCGCCGCAGCCGGAGCGGCGACGCGGGCCGCCGCTTACCGACTGAACTCCGGTATC
TCTTACCGTAGTGCGCGTTG

Product: hypothetical protein

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MARPQGLTRIDPALRDTAAQLGVVEFRAETLAAEREHANRLAAQRAASADTRGVAIDSVSIAGPDGQPLELRLYRGHTES
AAPLLVYAHGGAFVTGNLATDHAHCVELARDGGCLVVSVDYRLAPENPCPAALDDVEAAFRYVVDNSAALNADANRIAVM
GRDAGAALVAGLTQRMFDQEGPTILMQILHQPMLDSDATPSRREFQRTPGLNGPAVSRAWNHYLGHASASGQHVPAHRAN
LEGLPPTFISCSEIDPCRDEAIDYANRLLHAYVHTELHVIAATFNGFDSMVPDWIVAQENRALHAQALRRVFAM

Sequences:

>Translated_314_residues
MARPQGLTRIDPALRDTAAQLGVVEFRAETLAAEREHANRLAAQRAASADTRGVAIDSVSIAGPDGQPLELRLYRGHTES
AAPLLVYAHGGAFVTGNLATDHAHCVELARDGGCLVVSVDYRLAPENPCPAALDDVEAAFRYVVDNSAALNADANRIAVM
GRDAGAALVAGLTQRMFDQEGPTILMQILHQPMLDSDATPSRREFQRTPGLNGPAVSRAWNHYLGHASASGQHVPAHRAN
LEGLPPTFISCSEIDPCRDEAIDYANRLLHAYVHTELHVIAATFNGFDSMVPDWIVAQENRALHAQALRRVFAM
>Mature_313_residues
ARPQGLTRIDPALRDTAAQLGVVEFRAETLAAEREHANRLAAQRAASADTRGVAIDSVSIAGPDGQPLELRLYRGHTESA
APLLVYAHGGAFVTGNLATDHAHCVELARDGGCLVVSVDYRLAPENPCPAALDDVEAAFRYVVDNSAALNADANRIAVMG
RDAGAALVAGLTQRMFDQEGPTILMQILHQPMLDSDATPSRREFQRTPGLNGPAVSRAWNHYLGHASASGQHVPAHRANL
EGLPPTFISCSEIDPCRDEAIDYANRLLHAYVHTELHVIAATFNGFDSMVPDWIVAQENRALHAQALRRVFAM

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI157041239, Length=178, Percent_Identity=28.6516853932584, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17567059, Length=265, Percent_Identity=26.4150943396226, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI72001146, Length=199, Percent_Identity=28.643216080402, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 33830; Mature: 33699

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPQGLTRIDPALRDTAAQLGVVEFRAETLAAEREHANRLAAQRAASADTRGVAIDSVS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
IAGPDGQPLELRLYRGHTESAAPLLVYAHGGAFVTGNLATDHAHCVELARDGGCLVVSVD
EECCCCCCEEEEEEECCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHCCCCEEEEEEE
YRLAPENPCPAALDDVEAAFRYVVDNSAALNADANRIAVMGRDAGAALVAGLTQRMFDQE
EEECCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCEEEEEECCCCHHHHHHHHHHHHHCC
GPTILMQILHQPMLDSDATPSRREFQRTPGLNGPAVSRAWNHYLGHASASGQHVPAHRAN
CHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHCC
LEGLPPTFISCSEIDPCRDEAIDYANRLLHAYVHTELHVIAATFNGFDSMVPDWIVAQEN
CCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHCCCEEEECCC
RALHAQALRRVFAM
CHHHHHHHHHHHCC
>Mature Secondary Structure 
ARPQGLTRIDPALRDTAAQLGVVEFRAETLAAEREHANRLAAQRAASADTRGVAIDSVS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
IAGPDGQPLELRLYRGHTESAAPLLVYAHGGAFVTGNLATDHAHCVELARDGGCLVVSVD
EECCCCCCEEEEEEECCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHCCCCEEEEEEE
YRLAPENPCPAALDDVEAAFRYVVDNSAALNADANRIAVMGRDAGAALVAGLTQRMFDQE
EEECCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCEEEEEECCCCHHHHHHHHHHHHHCC
GPTILMQILHQPMLDSDATPSRREFQRTPGLNGPAVSRAWNHYLGHASASGQHVPAHRAN
CHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHCC
LEGLPPTFISCSEIDPCRDEAIDYANRLLHAYVHTELHVIAATFNGFDSMVPDWIVAQEN
CCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHCCCEEEECCC
RALHAQALRRVFAM
CHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]