Click here to switch to the map view.

The map label for this gene is fadE17

Identifier: 41408325

GI number: 41408325

Start: 2476941

End: 2478101

Strand: Direct

Name: fadE17

Synonym: MAP2227

Alternate gene names: 41408325

Gene position: 2476941-2478101 (Clockwise)

Preceding gene: 41408322

Following gene: 41408326

Centisome position: 51.28

GC content: 66.58

Gene sequence:

>1161_bases
ATGCAACTGGCGCTCACACCGGAGGAAGCCGCGTTCCGCGACGAGCTTCGCACCATCTACACGACCAAGATTCCCGAGGA
GCTGCGCGAGCGGGTGCGCCGGGGATCGGCGGAAGTGAACCGCGACGACATCGTCACCAGCCACAAGATCCTGCACGAGC
ACGGCCTTGCGGTACCGAACTGGCCGGTGGAGTGGGGCGGCAAGGACTGGACGCCCACCCAGCACCAGATCTGGGCCGAC
GAGATGCAGCTGGCCTGCGTCCCGGAGCCGTTGAACTTCAACACCAAGATGGTGGGCCCGGTGATCGCCGAATTCGGTTC
GGAGGAGGTCAAACAACGCTTCCTGCCCCCGACCGCCAGCCTCGACATCTGGTGGTGCCAGGGATTCTCCGAGCCGGACG
CCGGTTCGGACCTGGCGTCGCTGCGCACCACCGCGGTGCGCGACGGCGACCACTACATCGTCAACGGCCAGAAGACCTGG
ACCACGCTGGGCCAGTACGCCGACTGGATCTTCTGCCTGGTGCGCACCGACCCGCAGGCGCCCAAGCGCCAGGCCGGCAT
CTCGTTCCTGCTCTTCGACATGAAAAGCCCGGGCATCACGCTGCGGCCCATCAAGACGATCGACGGCGGCCACGAGATCA
ACGAGGTCTTCTTCGAGGACGTCCGGGTGCCCGCCGATCAGCTTGTCGGAGAAGAGAATCAGGGCTGGACGTACGCGAAG
TTCCTGCTGGGCAACGAACGCACCGGCATCGCCGGAGTGGGCCGCACCAAGGTGCGCCTGGCCGAGGTGAAGAAGCACGC
CGCGGCCACCGGGGTGCTCGACGATCCGCTGTTCGCCGCCCGGCTCGCCGAGGCCGAAAACGAGCTGCTGGCACTGGAAC
TCACGCAGTCGCGGGTGACCACCGACTCGGCGAACGGGCAGCCCAACCCGGCGTCGTCGGTGCTCAAGCTGCGGGGCAGC
CAACTGCAGCAGGTGGCCACCGAACTGCTCGTCGAGGTGGCCGGCCCGGATGCGTTGCCGGCCAAGGCCGACGACATCGC
CTCCCCGTCCTGGGCGCAATCCAGCGCGCCGCACTACCTGAACTATCGCAAGACGTCGATCTACGGCGGCAGCAGCGAAG
TACAGCGCAACATCATCGCGTCCACCATTCTGGGATTGTGA

Upstream 100 bases:

>100_bases
GCTGTGCACAGGGCCCGCACCCGATGGGTCAAGATGGAAGCCGAGCGAACGACCAGGGCGATGGGTCGCCACGTTCACCC
CGAAACGACAGGAGGCTGCC

Downstream 100 bases:

>100_bases
GGCAGCCATGGACTTTCAGTTGAGCGACGAGCAGGCCCTGCTGCGCGACACCACCCGCGATCTGCTGTCGCGCAGTTACG
ACCCGGAGAGCCGCAACAAG

Product: FadE17

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MQLALTPEEAAFRDELRTIYTTKIPEELRERVRRGSAEVNRDDIVTSHKILHEHGLAVPNWPVEWGGKDWTPTQHQIWAD
EMQLACVPEPLNFNTKMVGPVIAEFGSEEVKQRFLPPTASLDIWWCQGFSEPDAGSDLASLRTTAVRDGDHYIVNGQKTW
TTLGQYADWIFCLVRTDPQAPKRQAGISFLLFDMKSPGITLRPIKTIDGGHEINEVFFEDVRVPADQLVGEENQGWTYAK
FLLGNERTGIAGVGRTKVRLAEVKKHAAATGVLDDPLFAARLAEAENELLALELTQSRVTTDSANGQPNPASSVLKLRGS
QLQQVATELLVEVAGPDALPAKADDIASPSWAQSSAPHYLNYRKTSIYGGSSEVQRNIIASTILGL

Sequences:

>Translated_386_residues
MQLALTPEEAAFRDELRTIYTTKIPEELRERVRRGSAEVNRDDIVTSHKILHEHGLAVPNWPVEWGGKDWTPTQHQIWAD
EMQLACVPEPLNFNTKMVGPVIAEFGSEEVKQRFLPPTASLDIWWCQGFSEPDAGSDLASLRTTAVRDGDHYIVNGQKTW
TTLGQYADWIFCLVRTDPQAPKRQAGISFLLFDMKSPGITLRPIKTIDGGHEINEVFFEDVRVPADQLVGEENQGWTYAK
FLLGNERTGIAGVGRTKVRLAEVKKHAAATGVLDDPLFAARLAEAENELLALELTQSRVTTDSANGQPNPASSVLKLRGS
QLQQVATELLVEVAGPDALPAKADDIASPSWAQSSAPHYLNYRKTSIYGGSSEVQRNIIASTILGL
>Mature_386_residues
MQLALTPEEAAFRDELRTIYTTKIPEELRERVRRGSAEVNRDDIVTSHKILHEHGLAVPNWPVEWGGKDWTPTQHQIWAD
EMQLACVPEPLNFNTKMVGPVIAEFGSEEVKQRFLPPTASLDIWWCQGFSEPDAGSDLASLRTTAVRDGDHYIVNGQKTW
TTLGQYADWIFCLVRTDPQAPKRQAGISFLLFDMKSPGITLRPIKTIDGGHEINEVFFEDVRVPADQLVGEENQGWTYAK
FLLGNERTGIAGVGRTKVRLAEVKKHAAATGVLDDPLFAARLAEAENELLALELTQSRVTTDSANGQPNPASSVLKLRGS
QLQQVATELLVEVAGPDALPAKADDIASPSWAQSSAPHYLNYRKTSIYGGSSEVQRNIIASTILGL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=361, Percent_Identity=27.9778393351801, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4501857, Length=393, Percent_Identity=25.4452926208651, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI226958412, Length=197, Percent_Identity=30.4568527918782, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI226958414, Length=197, Percent_Identity=30.4568527918782, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI4557231, Length=344, Percent_Identity=26.7441860465116, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI187960098, Length=344, Percent_Identity=26.7441860465116, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI7656849, Length=212, Percent_Identity=28.7735849056604, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4557235, Length=265, Percent_Identity=30.9433962264151, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI76496475, Length=265, Percent_Identity=30.9433962264151, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI4501859, Length=206, Percent_Identity=27.6699029126214, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI38505218, Length=230, Percent_Identity=30, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI48976061, Length=245, Percent_Identity=27.7551020408163, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI211971008, Length=245, Percent_Identity=27.7551020408163, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI21361497, Length=255, Percent_Identity=28.2352941176471, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI87081958, Length=303, Percent_Identity=24.0924092409241, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17569725, Length=356, Percent_Identity=31.1797752808989, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17551932, Length=213, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17505929, Length=255, Percent_Identity=29.0196078431373, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17570075, Length=353, Percent_Identity=28.328611898017, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17534899, Length=350, Percent_Identity=27.1428571428571, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=254, Percent_Identity=27.9527559055118, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=360, Percent_Identity=25.8333333333333, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17506239, Length=406, Percent_Identity=24.1379310344828, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=170, Percent_Identity=30.5882352941176, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=210, Percent_Identity=27.6190476190476, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17533517, Length=202, Percent_Identity=27.2277227722772, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=155, Percent_Identity=32.9032258064516, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=155, Percent_Identity=32.9032258064516, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=195, Percent_Identity=28.2051282051282, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356377, Length=368, Percent_Identity=25.8152173913043, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281363737, Length=251, Percent_Identity=27.0916334661355, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24666513, Length=370, Percent_Identity=23.7837837837838, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24660351, Length=223, Percent_Identity=30.4932735426009, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646207, Length=363, Percent_Identity=25.6198347107438, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355753, Length=227, Percent_Identity=26.431718061674, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920834, Length=272, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 42606; Mature: 42606

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLALTPEEAAFRDELRTIYTTKIPEELRERVRRGSAEVNRDDIVTSHKILHEHGLAVPN
CCEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
WPVEWGGKDWTPTQHQIWADEMQLACVPEPLNFNTKMVGPVIAEFGSEEVKQRFLPPTAS
CCCCCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCCC
LDIWWCQGFSEPDAGSDLASLRTTAVRDGDHYIVNGQKTWTTLGQYADWIFCLVRTDPQA
EEEEEECCCCCCCCCCHHHHHHHHHEECCCEEEECCCHHHHHHHHHHCEEEEEEECCCCC
PKRQAGISFLLFDMKSPGITLRPIKTIDGGHEINEVFFEDVRVPADQLVGEENQGWTYAK
CHHHCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHCCCHHHHCCCCCCCCEEEE
FLLGNERTGIAGVGRTKVRLAEVKKHAAATGVLDDPLFAARLAEAENELLALELTQSRVT
EEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCCC
TDSANGQPNPASSVLKLRGSQLQQVATELLVEVAGPDALPAKADDIASPSWAQSSAPHYL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEE
NYRKTSIYGGSSEVQRNIIASTILGL
CCEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLALTPEEAAFRDELRTIYTTKIPEELRERVRRGSAEVNRDDIVTSHKILHEHGLAVPN
CCEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
WPVEWGGKDWTPTQHQIWADEMQLACVPEPLNFNTKMVGPVIAEFGSEEVKQRFLPPTAS
CCCCCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCCCC
LDIWWCQGFSEPDAGSDLASLRTTAVRDGDHYIVNGQKTWTTLGQYADWIFCLVRTDPQA
EEEEEECCCCCCCCCCHHHHHHHHHEECCCEEEECCCHHHHHHHHHHCEEEEEEECCCCC
PKRQAGISFLLFDMKSPGITLRPIKTIDGGHEINEVFFEDVRVPADQLVGEENQGWTYAK
CHHHCCCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHCCCHHHHCCCCCCCCEEEE
FLLGNERTGIAGVGRTKVRLAEVKKHAAATGVLDDPLFAARLAEAENELLALELTQSRVT
EEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCCC
TDSANGQPNPASSVLKLRGSQLQQVATELLVEVAGPDALPAKADDIASPSWAQSSAPHYL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEE
NYRKTSIYGGSSEVQRNIIASTILGL
CCEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]