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The map label for this gene is cysW

Identifier: 41408309

GI number: 41408309

Start: 2458451

End: 2459269

Strand: Reverse

Name: cysW

Synonym: MAP2211c

Alternate gene names: 41408309

Gene position: 2459269-2458451 (Counterclockwise)

Preceding gene: 41408310

Following gene: 41408308

Centisome position: 50.92

GC content: 67.16

Gene sequence:

>819_bases
ATGACGTCGTCGCCCGGGGTCCGCTATGGCCTGCGATTCGTGGCGCTGGCCTACATTTTCGTGCTGCTCGTCATTCCGGT
GAGCCTGATCCTGTGGCGGACGTTCCGGCCCGGGTTCGGCCAGTTCTATGCCTGGGTCAGCACCCCCGCGGCGATCTCGG
CACTGAACCTGACGCTGCTGGTGGTGGCCATCGTGGTGCCGCTCAACGTCTTCTTCGGCATCCCCACCGCACTGGTGCTG
GCGCGCAACAGGTTTCGGGGCAAGGGCGTGCTGCAGGCGATCATCGACCTGCCGTTCGCGGTGTCGCCCGTCATCGTGGG
CGTGGCGCTGATCGTGCTCTGGGGTTCGGCCGGTGCGCTCGGGTTCGTCGAAAAGGACCTCGGCTTCAAGATCATCTTCG
GTCTGCCCGGCATCGTGCTCGCCAGCATCTTCGTCACCCTGCCGTTCGTGGTGCGCGAGGTGGAACCGGTGCTGCACGAG
CTGGGGACCGACCAGGAGGAGGCGGCGGCCACCCTGGGTTCGGGCTGGTGGCAGACGTTTTGGCGGATCACGCTGCCGTC
CATCCGGTGGGGCCTGACCTACGGCATCGTGTTGACCATCGCACGTACCCTGGGGGAATACGGCGCGGTGCTGATGGTGT
CGTCGAACCTGCCGGGGAAGTCGCAGACGCTGACCCTGCTGGTCTCCGACCGCTACAACCGGGGCGCCGAGTACGGCGCC
TACGCGTTGTCGACGCTGCTGATGGGGGTTGCCGTGCTGGTGCTGGTTTTCCAGGTGGTTCTCGATGCCCGCCGCGGCCG
CGCGGCCGGGCAGGCCTGA

Upstream 100 bases:

>100_bases
CCGCCGCGATATCGATTGTGCTGTTGGCGATTTCCTTTGTGGTGCTGCTGATCCTGCGGGTGGTCGGTGGGCGCGCGGCC
AAGCGTGAGGAGCTGGCCGC

Downstream 100 bases:

>100_bases
CGAGGAGGCATGACGTGATCGACGCCGGTACCGACCGCGGCGACATCGCCATCACCGTGCGCGACGCCTACAAACGCTAC
GGCGACTTCGTCGCACTGGA

Product: CysW

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTSSPGVRYGLRFVALAYIFVLLVIPVSLILWRTFRPGFGQFYAWVSTPAAISALNLTLLVVAIVVPLNVFFGIPTALVL
ARNRFRGKGVLQAIIDLPFAVSPVIVGVALIVLWGSAGALGFVEKDLGFKIIFGLPGIVLASIFVTLPFVVREVEPVLHE
LGTDQEEAAATLGSGWWQTFWRITLPSIRWGLTYGIVLTIARTLGEYGAVLMVSSNLPGKSQTLTLLVSDRYNRGAEYGA
YALSTLLMGVAVLVLVFQVVLDARRGRAAGQA

Sequences:

>Translated_272_residues
MTSSPGVRYGLRFVALAYIFVLLVIPVSLILWRTFRPGFGQFYAWVSTPAAISALNLTLLVVAIVVPLNVFFGIPTALVL
ARNRFRGKGVLQAIIDLPFAVSPVIVGVALIVLWGSAGALGFVEKDLGFKIIFGLPGIVLASIFVTLPFVVREVEPVLHE
LGTDQEEAAATLGSGWWQTFWRITLPSIRWGLTYGIVLTIARTLGEYGAVLMVSSNLPGKSQTLTLLVSDRYNRGAEYGA
YALSTLLMGVAVLVLVFQVVLDARRGRAAGQA
>Mature_271_residues
TSSPGVRYGLRFVALAYIFVLLVIPVSLILWRTFRPGFGQFYAWVSTPAAISALNLTLLVVAIVVPLNVFFGIPTALVLA
RNRFRGKGVLQAIIDLPFAVSPVIVGVALIVLWGSAGALGFVEKDLGFKIIFGLPGIVLASIFVTLPFVVREVEPVLHEL
GTDQEEAAATLGSGWWQTFWRITLPSIRWGLTYGIVLTIARTLGEYGAVLMVSSNLPGKSQTLTLLVSDRYNRGAEYGAY
ALSTLLMGVAVLVLVFQVVLDARRGRAAGQA

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=255, Percent_Identity=40, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1788764, Length=230, Percent_Identity=33.9130434782609, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786980, Length=206, Percent_Identity=35.4368932038835, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29350; Mature: 29219

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSPGVRYGLRFVALAYIFVLLVIPVSLILWRTFRPGFGQFYAWVSTPAAISALNLTLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHH
VVAIVVPLNVFFGIPTALVLARNRFRGKGVLQAIIDLPFAVSPVIVGVALIVLWGSAGAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GFVEKDLGFKIIFGLPGIVLASIFVTLPFVVREVEPVLHELGTDQEEAAATLGSGWWQTF
CHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHH
WRITLPSIRWGLTYGIVLTIARTLGEYGAVLMVSSNLPGKSQTLTLLVSDRYNRGAEYGA
HHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEEECCCCCCCHHHH
YALSTLLMGVAVLVLVFQVVLDARRGRAAGQA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TSSPGVRYGLRFVALAYIFVLLVIPVSLILWRTFRPGFGQFYAWVSTPAAISALNLTLL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHH
VVAIVVPLNVFFGIPTALVLARNRFRGKGVLQAIIDLPFAVSPVIVGVALIVLWGSAGAL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GFVEKDLGFKIIFGLPGIVLASIFVTLPFVVREVEPVLHELGTDQEEAAATLGSGWWQTF
CHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHH
WRITLPSIRWGLTYGIVLTIARTLGEYGAVLMVSSNLPGKSQTLTLLVSDRYNRGAEYGA
HHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEEECCCCCCCHHHH
YALSTLLMGVAVLVLVFQVVLDARRGRAAGQA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1708375 [H]