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The map label for this gene is dosT [H]

Identifier: 41408176

GI number: 41408176

Start: 2286247

End: 2288922

Strand: Reverse

Name: dosT [H]

Synonym: MAP2078c

Alternate gene names: 41408176

Gene position: 2288922-2286247 (Counterclockwise)

Preceding gene: 41408181

Following gene: 41408175

Centisome position: 47.39

GC content: 69.69

Gene sequence:

>2676_bases
ATGGCGCCCGAACGGCTAAGGCGCCGTACGGTGACCGGCGCTGGCCGCATGGTGCCGGGAGGTGCGGCACCGACATGGCC
GCGCACCCGACCGTTTACTTTGGTATCCATGGACAGCGACCGGGATGACTCCGCCGCCATCCGGCGGGACCGGCGCGAAC
TGGACCGCATGCACACCCAGCTCGACGAGCTGATGGCTGCGCGCGACCAGCTGGAACAACTGGTGCGGGTCATCGTCGAA
ATCGGCTCCGATCTGGACTTGGACGTCACGCTGCGTCGCGTCCTGAAAGCGGCGATGGAGCTGACCGGCGCCCGCTACGC
CGTGCTCTCTTCCCGCGCCTCCGACGGCGCACTCCTCTCGTTCGTGCATGCCGGCCTCGACGCGGACACGGCCCGGCAGC
TCGGCGAGCTCGCGGTGGGCGACGGTCTTCGCATCGACGATGTGAGCGTTGATGCGCGCAGCGCCCACCTGTCGGCACAC
GACCCACCGCTGCGGGCGCTGCTGGGAATACCGATCACGGTGCGGGCAGCCAACTTTGGCAACCTCTATCTGGCGGACGA
CCGGCAAGGGCGCGTGTTCACCGACTCGCAGGAAGGCGCGGTGCGCGCCATGGCCACGGCGGCAGCCGCCGCCATCGACA
ACGCGCGACTCTTCGAGCGCGAGCGTGAATCGGCGAAATGGACGAAGGCCAGTCGCGAGATCACCACCGCGCTGCTGTCC
GGTGATCCGCAGACGGGTCCGTTGCAGCTCATTGTGAACCGGGCGCTGGAGCTGGCCGGCGCCGAGCAGGCGATCTTGCT
GGTCCCGCGAGAGCCCGAGTCGCCCGGCCGGGAGGCCGACACCCTGGTGGTGTCCGCCACCGCGGGCCGCTATGCCTCGC
AGGTGATCGGCCGGCAGGTTCCGATGGACGGCTCGACCACCGGCGGTGTCGCGCGGCGCGGCCTGCCGTTGATTACCGAC
TCCTTCCAATACCCGATCGAGGGATTCACCGACGTCGGCGAACGCTCGGCGATCGTGATACCGCTGATTGCCGACGGCGC
GGTGCTCGGCGTCATCGCCGTCGCGCGCGACCCGCAGCAGCCGCCGTTCGGCAACGACTACCTCGACCTGGTCAGTGACT
TCGCCCGGCACGCCGCCATCGCCTTGGCGCTGGCGGCGGGCCGCCAACACGCGCTCAATCAGGAACTGGCCCAAGCGGAT
ACGGTCGACGAGGCGGTACGCGCCGCGGCTGAAGAACTGCGCCGGCTGTGGCGCGCCCGCCGGGTGCTGGCCGTCACCTT
CCCAAGCCACACCTCTGCTACGGAAACGGCGTTCGGCCCGCCCGAGGTCGTTTCGGTCGGCGAGCCCACGCAGTGGGCCG
ATCTGCCGTCGCACATGCACCAGGCGCTCGGCGCGTTGCGCGACGGCGACCTGCTCACCCCGAACACCACGCAGCCCGGG
ACGGCGGGCATCGCCCTGCAGCATCCCGACGGCGTGCTGGTCGTCTGGATCGACCTGACCGATGAGCGTTCGTTCACCTT
GGAAGACCAGACCCTGCTCACCGTGCTGGCCGGCCGCCTCGGCCAGGGCCTGCAACGGGTGCACCAGGTCGACCAGCAGC
GCGAAACCGCACTGGCTCTGCAGCACGCGATCCTCGGTCCCGCCGATCTGCCCAACGGATTCGCGGTGCGCTATCAGGCC
GCCACCCGGCCGTTGCAGGTCGGTGGTGACTGGTTCGACATCGTCGACCTCGAGGACGGGCGGGTCGCGTTGGTCGTCGG
CGACTGTGTCGGCCATGGGCTCGCGTCCGCCACGGTGATGGGTCAGGTGCGCAGCGCCTGCCGCGCCCTGCTGCTCGAAA
ACCCAAGTCCTGCTGCGGCTCTCGCGGGTCTGGACCGATTCGCGGCGCGGCTGCCCGGCGCGCAATGCACCACCGCCGTG
TGCGCGGTGCTCACCCCGGACACCGGTGAACTGGTCTACTCCAGCGCCGGGCACCCGCCGCCCATCGTGGTGCACGGCGA
CGGCAGCACCCAGATACTCGACGAGGGCCACACCATCGCATTGGGCATCCGACGGGACTGGCCCCGCCCGGAGGCCCGGG
TGACCATACCGGCGCGCGCGACCCTGCTGTTGTACACCGACGGGCTGGTCGAACGTCGCCGCAGCCCGCTGGATCGGGGT
ATCTACCGCGTCGCCACCGTCGCGCAGGATGCGCGCGGCTCGTCCCTCGACGAGTTGGCGACCCGGATCATGTCCGCCGT
CGCGCCGAGCGGCGGCTACCAGGACGACGTGGTGTTGCTGCTGTACCGGCATCCGGCGCCGCTGGAGCTGAACTTCCCCG
CCGACGTCAACCAGCTGGCGCCCACTCGCACCGCGTTGCGCAACTGGCTGCGCCGTGTCCGGCTGGACCCGGAGCAGACG
TTGAACGTACTGGTCGCCGCCGGGGAGGCGGTCGCCAACGCCATCGAGCACGGACACCGGCACAGCCCGCAGGGCACAAT
TCGACTGGGCGCCACCGCGTTAGGCGATCAGGTCCGGTTGACGATCACCGACACCGGCACATGGAAGGTTCCCCAAGCGA
CGTCCTATCCGCATCGGGGGCGGGGCATCCCGTTGATGAAAAGCCTGATGAACGATGTCGACATTCGGTCCGACACCGGC
GGAACCACCGTCCAGCTCTCCGCAAGGATCACCTGA

Upstream 100 bases:

>100_bases
CCCCAGCTCCACCGGTAAAAGGGTACTCATCTCGATGATCGTCGGCGGCGCAATTCAATACCTGGTCAAGATCCGGTAAA
GCCGCCGGTGACCTGCCCGG

Downstream 100 bases:

>100_bases
TGGTCACCCCGCTGACGCTGGACACCGGCCGTGGTAGCGACGGCAACCCGGTGCTGGTGGCAGTGGGCGAAATCGACCTG
AGCAACATCGACGCATTCCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 891; Mature: 890

Protein sequence:

>891_residues
MAPERLRRRTVTGAGRMVPGGAAPTWPRTRPFTLVSMDSDRDDSAAIRRDRRELDRMHTQLDELMAARDQLEQLVRVIVE
IGSDLDLDVTLRRVLKAAMELTGARYAVLSSRASDGALLSFVHAGLDADTARQLGELAVGDGLRIDDVSVDARSAHLSAH
DPPLRALLGIPITVRAANFGNLYLADDRQGRVFTDSQEGAVRAMATAAAAAIDNARLFERERESAKWTKASREITTALLS
GDPQTGPLQLIVNRALELAGAEQAILLVPREPESPGREADTLVVSATAGRYASQVIGRQVPMDGSTTGGVARRGLPLITD
SFQYPIEGFTDVGERSAIVIPLIADGAVLGVIAVARDPQQPPFGNDYLDLVSDFARHAAIALALAAGRQHALNQELAQAD
TVDEAVRAAAEELRRLWRARRVLAVTFPSHTSATETAFGPPEVVSVGEPTQWADLPSHMHQALGALRDGDLLTPNTTQPG
TAGIALQHPDGVLVVWIDLTDERSFTLEDQTLLTVLAGRLGQGLQRVHQVDQQRETALALQHAILGPADLPNGFAVRYQA
ATRPLQVGGDWFDIVDLEDGRVALVVGDCVGHGLASATVMGQVRSACRALLLENPSPAAALAGLDRFAARLPGAQCTTAV
CAVLTPDTGELVYSSAGHPPPIVVHGDGSTQILDEGHTIALGIRRDWPRPEARVTIPARATLLLYTDGLVERRRSPLDRG
IYRVATVAQDARGSSLDELATRIMSAVAPSGGYQDDVVLLLYRHPAPLELNFPADVNQLAPTRTALRNWLRRVRLDPEQT
LNVLVAAGEAVANAIEHGHRHSPQGTIRLGATALGDQVRLTITDTGTWKVPQATSYPHRGRGIPLMKSLMNDVDIRSDTG
GTTVQLSARIT

Sequences:

>Translated_891_residues
MAPERLRRRTVTGAGRMVPGGAAPTWPRTRPFTLVSMDSDRDDSAAIRRDRRELDRMHTQLDELMAARDQLEQLVRVIVE
IGSDLDLDVTLRRVLKAAMELTGARYAVLSSRASDGALLSFVHAGLDADTARQLGELAVGDGLRIDDVSVDARSAHLSAH
DPPLRALLGIPITVRAANFGNLYLADDRQGRVFTDSQEGAVRAMATAAAAAIDNARLFERERESAKWTKASREITTALLS
GDPQTGPLQLIVNRALELAGAEQAILLVPREPESPGREADTLVVSATAGRYASQVIGRQVPMDGSTTGGVARRGLPLITD
SFQYPIEGFTDVGERSAIVIPLIADGAVLGVIAVARDPQQPPFGNDYLDLVSDFARHAAIALALAAGRQHALNQELAQAD
TVDEAVRAAAEELRRLWRARRVLAVTFPSHTSATETAFGPPEVVSVGEPTQWADLPSHMHQALGALRDGDLLTPNTTQPG
TAGIALQHPDGVLVVWIDLTDERSFTLEDQTLLTVLAGRLGQGLQRVHQVDQQRETALALQHAILGPADLPNGFAVRYQA
ATRPLQVGGDWFDIVDLEDGRVALVVGDCVGHGLASATVMGQVRSACRALLLENPSPAAALAGLDRFAARLPGAQCTTAV
CAVLTPDTGELVYSSAGHPPPIVVHGDGSTQILDEGHTIALGIRRDWPRPEARVTIPARATLLLYTDGLVERRRSPLDRG
IYRVATVAQDARGSSLDELATRIMSAVAPSGGYQDDVVLLLYRHPAPLELNFPADVNQLAPTRTALRNWLRRVRLDPEQT
LNVLVAAGEAVANAIEHGHRHSPQGTIRLGATALGDQVRLTITDTGTWKVPQATSYPHRGRGIPLMKSLMNDVDIRSDTG
GTTVQLSARIT
>Mature_890_residues
APERLRRRTVTGAGRMVPGGAAPTWPRTRPFTLVSMDSDRDDSAAIRRDRRELDRMHTQLDELMAARDQLEQLVRVIVEI
GSDLDLDVTLRRVLKAAMELTGARYAVLSSRASDGALLSFVHAGLDADTARQLGELAVGDGLRIDDVSVDARSAHLSAHD
PPLRALLGIPITVRAANFGNLYLADDRQGRVFTDSQEGAVRAMATAAAAAIDNARLFERERESAKWTKASREITTALLSG
DPQTGPLQLIVNRALELAGAEQAILLVPREPESPGREADTLVVSATAGRYASQVIGRQVPMDGSTTGGVARRGLPLITDS
FQYPIEGFTDVGERSAIVIPLIADGAVLGVIAVARDPQQPPFGNDYLDLVSDFARHAAIALALAAGRQHALNQELAQADT
VDEAVRAAAEELRRLWRARRVLAVTFPSHTSATETAFGPPEVVSVGEPTQWADLPSHMHQALGALRDGDLLTPNTTQPGT
AGIALQHPDGVLVVWIDLTDERSFTLEDQTLLTVLAGRLGQGLQRVHQVDQQRETALALQHAILGPADLPNGFAVRYQAA
TRPLQVGGDWFDIVDLEDGRVALVVGDCVGHGLASATVMGQVRSACRALLLENPSPAAALAGLDRFAARLPGAQCTTAVC
AVLTPDTGELVYSSAGHPPPIVVHGDGSTQILDEGHTIALGIRRDWPRPEARVTIPARATLLLYTDGLVERRRSPLDRGI
YRVATVAQDARGSSLDELATRIMSAVAPSGGYQDDVVLLLYRHPAPLELNFPADVNQLAPTRTALRNWLRRVRLDPEQTL
NVLVAAGEAVANAIEHGHRHSPQGTIRLGATALGDQVRLTITDTGTWKVPQATSYPHRGRGIPLMKSLMNDVDIRSDTGG
TTVQLSARIT

Specific function: Interacts with the two-component regulatory system devR/devS (dosR/dosS) involved in onset of the dormancy response. May act as a direct hypoxia sensor (rather than a redox sensor); the normal state is the oxygenated form, while the deoxy form is probably

COG id: COG2203

COG function: function code T; FOG: GAF domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: NA

Molecular weight: Translated: 95589; Mature: 95458

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPERLRRRTVTGAGRMVPGGAAPTWPRTRPFTLVSMDSDRDDSAAIRRDRRELDRMHTQ
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
LDELMAARDQLEQLVRVIVEIGSDLDLDVTLRRVLKAAMELTGARYAVLSSRASDGALLS
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
FVHAGLDADTARQLGELAVGDGLRIDDVSVDARSAHLSAHDPPLRALLGIPITVRAANFG
HHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCC
NLYLADDRQGRVFTDSQEGAVRAMATAAAAAIDNARLFERERESAKWTKASREITTALLS
CEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDPQTGPLQLIVNRALELAGAEQAILLVPREPESPGREADTLVVSATAGRYASQVIGRQV
CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHCCCC
PMDGSTTGGVARRGLPLITDSFQYPIEGFTDVGERSAIVIPLIADGAVLGVIAVARDPQQ
CCCCCCCCCHHHCCCCEEECCCCCCCCCCCCCCCCCEEEEEEECCCCEEEHEEECCCCCC
PPFGNDYLDLVSDFARHAAIALALAAGRQHALNQELAQADTVDEAVRAAAEELRRLWRAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RVLAVTFPSHTSATETAFGPPEVVSVGEPTQWADLPSHMHQALGALRDGDLLTPNTTQPG
EEEEEEECCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCC
TAGIALQHPDGVLVVWIDLTDERSFTLEDQTLLTVLAGRLGQGLQRVHQVDQQRETALAL
CCCEEEECCCCEEEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QHAILGPADLPNGFAVRYQAATRPLQVGGDWFDIVDLEDGRVALVVGDCVGHGLASATVM
HHHHCCCCCCCCCEEEEEECCCCCEEECCCEEEEEECCCCEEEEEEECHHCCCHHHHHHH
GQVRSACRALLLENPSPAAALAGLDRFAARLPGAQCTTAVCAVLTPDTGELVYSSAGHPP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHEEEEECCCCCCEEECCCCCCC
PIVVHGDGSTQILDEGHTIALGIRRDWPRPEARVTIPARATLLLYTDGLVERRRSPLDRG
CEEEECCCCCEEECCCCEEEEEEECCCCCCCCEEEECCCEEEEEEECHHHHHHCCCHHHH
IYRVATVAQDARGSSLDELATRIMSAVAPSGGYQDDVVLLLYRHPAPLELNFPADVNQLA
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEECCCCCHHCC
PTRTALRNWLRRVRLDPEQTLNVLVAAGEAVANAIEHGHRHSPQGTIRLGATALGDQVRL
HHHHHHHHHHHHHCCCHHHHHHHHEECCHHHHHHHHHCCCCCCCCEEEECCEECCCEEEE
TITDTGTWKVPQATSYPHRGRGIPLMKSLMNDVDIRSDTGGTTVQLSARIT
EEECCCCEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
APERLRRRTVTGAGRMVPGGAAPTWPRTRPFTLVSMDSDRDDSAAIRRDRRELDRMHTQ
CCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
LDELMAARDQLEQLVRVIVEIGSDLDLDVTLRRVLKAAMELTGARYAVLSSRASDGALLS
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
FVHAGLDADTARQLGELAVGDGLRIDDVSVDARSAHLSAHDPPLRALLGIPITVRAANFG
HHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCC
NLYLADDRQGRVFTDSQEGAVRAMATAAAAAIDNARLFERERESAKWTKASREITTALLS
CEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDPQTGPLQLIVNRALELAGAEQAILLVPREPESPGREADTLVVSATAGRYASQVIGRQV
CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHCCCC
PMDGSTTGGVARRGLPLITDSFQYPIEGFTDVGERSAIVIPLIADGAVLGVIAVARDPQQ
CCCCCCCCCHHHCCCCEEECCCCCCCCCCCCCCCCCEEEEEEECCCCEEEHEEECCCCCC
PPFGNDYLDLVSDFARHAAIALALAAGRQHALNQELAQADTVDEAVRAAAEELRRLWRAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RVLAVTFPSHTSATETAFGPPEVVSVGEPTQWADLPSHMHQALGALRDGDLLTPNTTQPG
EEEEEEECCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCEECCCCCCCC
TAGIALQHPDGVLVVWIDLTDERSFTLEDQTLLTVLAGRLGQGLQRVHQVDQQRETALAL
CCCEEEECCCCEEEEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QHAILGPADLPNGFAVRYQAATRPLQVGGDWFDIVDLEDGRVALVVGDCVGHGLASATVM
HHHHCCCCCCCCCEEEEEECCCCCEEECCCEEEEEECCCCEEEEEEECHHCCCHHHHHHH
GQVRSACRALLLENPSPAAALAGLDRFAARLPGAQCTTAVCAVLTPDTGELVYSSAGHPP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHEEEEECCCCCCEEECCCCCCC
PIVVHGDGSTQILDEGHTIALGIRRDWPRPEARVTIPARATLLLYTDGLVERRRSPLDRG
CEEEECCCCCEEECCCCEEEEEEECCCCCCCCEEEECCCEEEEEEECHHHHHHCCCHHHH
IYRVATVAQDARGSSLDELATRIMSAVAPSGGYQDDVVLLLYRHPAPLELNFPADVNQLA
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEECCCCCHHCC
PTRTALRNWLRRVRLDPEQTLNVLVAAGEAVANAIEHGHRHSPQGTIRLGATALGDQVRL
HHHHHHHHHHHHHCCCHHHHHHHHEECCHHHHHHHHHCCCCCCCCEEEECCEECCCEEEE
TITDTGTWKVPQATSYPHRGRGIPLMKSLMNDVDIRSDTGGTTVQLSARIT
EEECCCCEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]