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The map label for this gene is glpD1

Identifier: 41408100

GI number: 41408100

Start: 2209721

End: 2211262

Strand: Reverse

Name: glpD1

Synonym: MAP2002c

Alternate gene names: 41408100

Gene position: 2211262-2209721 (Counterclockwise)

Preceding gene: 41408101

Following gene: 41408099

Centisome position: 45.78

GC content: 72.44

Gene sequence:

>1542_bases
GTGATCCCCGACCCCAGCGCGCTCAACGCCGCCCGCCGGACCGCCGACCTGGCCGCGCTCGCCGAGGGTGAGCCGCTGGA
CGTGCTGGTGATCGGCGGCGGCATCACCGGGGCCGGGATCGCGTTGGACGCCGCCGCGCGCGGGCTGCGGGTGGCGCTGG
TGGAAAAGCGCGATCTGGCGTTCGGCACCAGCCGCTGGAGCTCCAAACTCGTGCACGGCGGGCTGCGCTATCTGGCCAGC
GGCAACGTCGGCATCGCCCGGCGCAGCGCCCTCGAACGCGGAATCCTGATGACCCGCAACGCCCCTCATCTGGTGCACGC
GATGCCGCAACTGGTGCCGTTGCTGCCGTCAATGAGCCGGGCCACGCGGGCGCTGGTGCGCGGCGGCTTCCTGGCCGGCG
ACGCGCTGCGCTTCCTCGCCGGCACGCCGGCCTCGACACTGCCCCGCTCGCAACGGGTCTCGGCGCAGCGCGTCGTGCAG
CTGGCGCCGACCGTGCGCCGCGACGGCCTGGACGGGGGATTGCTGGCCTACGACGGTCAACTGATCGACGACGCCCGGCT
GGTCACCGCGGTGGCGCGCACCGCCGCTCAGCACGGCGCCCGGATCCTCACCTACGTCGCGGCGTCGCGGGCCACGGGCA
CGTCGGTGCGGTTGACCGACGTGCGTGGCGGCGGCTCGTTCGACGTGTCGGCCGGCGCGGTGATCAACGCGGCCGGCGTG
TGGGCGGGCGAGATCGACGGCTCGTTGCGGTTGCGGCCCAGCCGCGGCACGCATCTGGTCTTCGACGCCGCCGCCTTCGG
CAATCCGACTGCGGCGCTGACGATTCCGATTCCCGGCGAGCTCAACAGATTCGTCTTCGCGATGCCCGAACAGCTGGGCC
GGGTCTACCTCGGGCTGACTGACGAGGCCGCGCCCGGTCCCATCCCGGACGTGCCGGAGCCGTCCGTCGAGGAGATCACG
TTCCTGCTCGACACGGTGAACACCGCGCTGGGCACGGCGCTGGCCGCCACCGACGTGAGCGGCGCCTACGCGGGGCTGCG
GCCGCTGATCGACACGGGTGAGGGCCGCACCGCCGACGTCTCCCGCGAACACGCCGTCGTCGAATCCGCGTCCGGGGTGA
TCAGCGTGATCGGCGGCAAACTGACCGAATACCGTTACATGGCACAGGATGTGCTCGATCGTGCCGTGCGGGTGCGGCGG
CTGCGCGCCGCGAAATGCCAGACCCGCAACCTGCCGCTGATCGGGGCGCCGGCCAACCCCGGGATCACCGGAGCGCCGCA
CGTCGCACTGCCGGAGTCACTCGTGTCGCGGTACGGCGCCGAGGCGGCCAAGGTCGTCGCGACCGCCGGTTGCGAGCGGC
CGACCGAACCGGTCGTCGACGGAATCGACGTCACCCGAGCCGAGTTCGAATACGCGATCACCTACGAATGCGCGCTGGAG
GTCTCCGACATCGTCGATCGGCGGACCCGGATCGGCCTGGTGCCGCGCGACCGCGAGCGGGTGGTGGCCGTGGCCGAGGA
GTTTCTCGCCCGCTTCGGGTAG

Upstream 100 bases:

>100_bases
TCGCCCAGTCGACCATCCAGTCGGCGCAGATCGTCGAACCGCTGCTCGACGCCGAGGCGCTGGCCAAGGAACTCGCCTAC
TCGCTGAACGGATACCTGTC

Downstream 100 bases:

>100_bases
GGCGGCTGGTCACCCCCCACCCGTCAGGTATTGATAGTTCCTATCGAATGATAGAAACTGTCAGTTCTGGTGGGGTGTCG
AAAGGGGACGAGATGACCAC

Product: GlpD1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MIPDPSALNAARRTADLAALAEGEPLDVLVIGGGITGAGIALDAAARGLRVALVEKRDLAFGTSRWSSKLVHGGLRYLAS
GNVGIARRSALERGILMTRNAPHLVHAMPQLVPLLPSMSRATRALVRGGFLAGDALRFLAGTPASTLPRSQRVSAQRVVQ
LAPTVRRDGLDGGLLAYDGQLIDDARLVTAVARTAAQHGARILTYVAASRATGTSVRLTDVRGGGSFDVSAGAVINAAGV
WAGEIDGSLRLRPSRGTHLVFDAAAFGNPTAALTIPIPGELNRFVFAMPEQLGRVYLGLTDEAAPGPIPDVPEPSVEEIT
FLLDTVNTALGTALAATDVSGAYAGLRPLIDTGEGRTADVSREHAVVESASGVISVIGGKLTEYRYMAQDVLDRAVRVRR
LRAAKCQTRNLPLIGAPANPGITGAPHVALPESLVSRYGAEAAKVVATAGCERPTEPVVDGIDVTRAEFEYAITYECALE
VSDIVDRRTRIGLVPRDRERVVAVAEEFLARFG

Sequences:

>Translated_513_residues
MIPDPSALNAARRTADLAALAEGEPLDVLVIGGGITGAGIALDAAARGLRVALVEKRDLAFGTSRWSSKLVHGGLRYLAS
GNVGIARRSALERGILMTRNAPHLVHAMPQLVPLLPSMSRATRALVRGGFLAGDALRFLAGTPASTLPRSQRVSAQRVVQ
LAPTVRRDGLDGGLLAYDGQLIDDARLVTAVARTAAQHGARILTYVAASRATGTSVRLTDVRGGGSFDVSAGAVINAAGV
WAGEIDGSLRLRPSRGTHLVFDAAAFGNPTAALTIPIPGELNRFVFAMPEQLGRVYLGLTDEAAPGPIPDVPEPSVEEIT
FLLDTVNTALGTALAATDVSGAYAGLRPLIDTGEGRTADVSREHAVVESASGVISVIGGKLTEYRYMAQDVLDRAVRVRR
LRAAKCQTRNLPLIGAPANPGITGAPHVALPESLVSRYGAEAAKVVATAGCERPTEPVVDGIDVTRAEFEYAITYECALE
VSDIVDRRTRIGLVPRDRERVVAVAEEFLARFG
>Mature_513_residues
MIPDPSALNAARRTADLAALAEGEPLDVLVIGGGITGAGIALDAAARGLRVALVEKRDLAFGTSRWSSKLVHGGLRYLAS
GNVGIARRSALERGILMTRNAPHLVHAMPQLVPLLPSMSRATRALVRGGFLAGDALRFLAGTPASTLPRSQRVSAQRVVQ
LAPTVRRDGLDGGLLAYDGQLIDDARLVTAVARTAAQHGARILTYVAASRATGTSVRLTDVRGGGSFDVSAGAVINAAGV
WAGEIDGSLRLRPSRGTHLVFDAAAFGNPTAALTIPIPGELNRFVFAMPEQLGRVYLGLTDEAAPGPIPDVPEPSVEEIT
FLLDTVNTALGTALAATDVSGAYAGLRPLIDTGEGRTADVSREHAVVESASGVISVIGGKLTEYRYMAQDVLDRAVRVRR
LRAAKCQTRNLPLIGAPANPGITGAPHVALPESLVSRYGAEAAKVVATAGCERPTEPVVDGIDVTRAEFEYAITYECALE
VSDIVDRRTRIGLVPRDRERVVAVAEEFLARFG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=564, Percent_Identity=31.5602836879433, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI285002231, Length=564, Percent_Identity=31.5602836879433, Blast_Score=204, Evalue=2e-52,
Organism=Escherichia coli, GI2367226, Length=474, Percent_Identity=27.8481012658228, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788574, Length=502, Percent_Identity=28.6852589641434, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17509253, Length=534, Percent_Identity=31.2734082397004, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI115534726, Length=521, Percent_Identity=30.9021113243762, Blast_Score=167, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6322036, Length=535, Percent_Identity=28.9719626168224, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI161077125, Length=564, Percent_Identity=30.6737588652482, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24653942, Length=564, Percent_Identity=30.6737588652482, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24653944, Length=564, Percent_Identity=30.6737588652482, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI20130025, Length=564, Percent_Identity=30.6737588652482, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24586295, Length=523, Percent_Identity=28.2982791586998, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI19921278, Length=565, Percent_Identity=26.1946902654867, Blast_Score=112, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 53823; Mature: 53823

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPDPSALNAARRTADLAALAEGEPLDVLVIGGGITGAGIALDAAARGLRVALVEKRDLA
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCEEEEEEECCCCC
FGTSRWSSKLVHGGLRYLASGNVGIARRSALERGILMTRNAPHLVHAMPQLVPLLPSMSR
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCHHH
ATRALVRGGFLAGDALRFLAGTPASTLPRSQRVSAQRVVQLAPTVRRDGLDGGLLAYDGQ
HHHHHHHCCCHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCHHHHCCCCCCEEEECCE
LIDDARLVTAVARTAAQHGARILTYVAASRATGTSVRLTDVRGGGSFDVSAGAVINAAGV
ECCHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCEEEEEEECCCCCCCCCCCCEEEECCE
WAGEIDGSLRLRPSRGTHLVFDAAAFGNPTAALTIPIPGELNRFVFAMPEQLGRVYLGLT
EEECCCCEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCHHEEECCHHHCEEEEEEC
DEAAPGPIPDVPEPSVEEITFLLDTVNTALGTALAATDVSGAYAGLRPLIDTGEGRTADV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHCCCCCCCCCC
SREHAVVESASGVISVIGGKLTEYRYMAQDVLDRAVRVRRLRAAKCQTRNLPLIGAPANP
CHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
GITGAPHVALPESLVSRYGAEAAKVVATAGCERPTEPVVDGIDVTRAEFEYAITYECALE
CCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCHHHCCCCCCHHHEEEEEEEEEEEE
VSDIVDRRTRIGLVPRDRERVVAVAEEFLARFG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIPDPSALNAARRTADLAALAEGEPLDVLVIGGGITGAGIALDAAARGLRVALVEKRDLA
CCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCEEEEEEECCCCC
FGTSRWSSKLVHGGLRYLASGNVGIARRSALERGILMTRNAPHLVHAMPQLVPLLPSMSR
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCCCHHH
ATRALVRGGFLAGDALRFLAGTPASTLPRSQRVSAQRVVQLAPTVRRDGLDGGLLAYDGQ
HHHHHHHCCCHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCHHHHCCCCCCEEEECCE
LIDDARLVTAVARTAAQHGARILTYVAASRATGTSVRLTDVRGGGSFDVSAGAVINAAGV
ECCHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCEEEEEEECCCCCCCCCCCCEEEECCE
WAGEIDGSLRLRPSRGTHLVFDAAAFGNPTAALTIPIPGELNRFVFAMPEQLGRVYLGLT
EEECCCCEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCCHHEEECCHHHCEEEEEEC
DEAAPGPIPDVPEPSVEEITFLLDTVNTALGTALAATDVSGAYAGLRPLIDTGEGRTADV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHCCCCCCCCCC
SREHAVVESASGVISVIGGKLTEYRYMAQDVLDRAVRVRRLRAAKCQTRNLPLIGAPANP
CHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
GITGAPHVALPESLVSRYGAEAAKVVATAGCERPTEPVVDGIDVTRAEFEYAITYECALE
CCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCHHHCCCCCCHHHEEEEEEEEEEEE
VSDIVDRRTRIGLVPRDRERVVAVAEEFLARFG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]