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The map label for this gene is 41408017

Identifier: 41408017

GI number: 41408017

Start: 2120141

End: 2121430

Strand: Direct

Name: 41408017

Synonym: MAP1919

Alternate gene names: NA

Gene position: 2120141-2121430 (Clockwise)

Preceding gene: 41408013

Following gene: 41408023

Centisome position: 43.9

GC content: 71.24

Gene sequence:

>1290_bases
ATGAGTACGCGGCAAGCACCCGGGGCCGGCTTCCCAGGCAAACGACCGGGGTGGGCGCTGTGGTGGGGGTTGGCGTGGCT
GACGGCCGCCGCCGCCCTCGGGTACGCGGCGTGGCAGTTGTTCGGGCACACCCCCTATCGCATCGACATCGACGTGTATC
AGATGGGCGCCCGGGCCTGGATGGACGGCCGCCCGCTGTACCGCGGAGACGTGCTGTTCCACACACCGATCGTGGATCTG
CCGTTCACCTATCCGCCGCTGGCCGCCATCGTGTTCTGCCCGTTCGCCTGGATGCACATGCCGACGGCCAGTGTGGCGAT
CACCGCCCTGACGTTGGTGTTGCTGGTCGTCTCGACCGTGATCGTGCTGGCCCGCCTCGACGTGTGGAGCACCTCGGCGC
TGCTGCCCGGCCCGGCCTGGCTGCGCCGGTGGTGGCTGGCCGTGGTGGTCGCGGCGGCCGCCACGATCTGGCTGGAGCCG
ATCAGTTCGAACTTCGCCTTCGGCCAGATCAACGTGGTACTGATGACGCTGGTGATCGCCGACTGCCTGCCGCGGCGCAC
GCCGTGGCCGCGCGGCCTGCTGCTGGGGCTGGGCATGGCGCTGAAACTGACGCCCGCGGTGTTTCTGCTCTATTTCCTGC
TGCGCCGCGACCACCGCGCGGTGCTCACCGCGCTGGCCTCGTTCGCGGGGGCGACGCTGCTCGGTTTCGTCCTGGCCTAC
ACCGACTCGTGGGAGTACTGGACGCACACCGTGCACCACACCGACCGGATCGGTTCCGCGTCGCTGAACACCGACCAGAA
CATCGCCGGCGCGCTGGCCCGCCTGGGGCTGGCGCAGCAGCCGCGGTCGCTGCTGTGGGTGGCGGCGTCGCTGCTGGTGC
TGGCGGTGACGGTGTGGGCGATGCGGCGGGTGCTGCGCGCCGACGAGCCGACGCTGGCGCTGGTGTGCGTCGCGCTGTTC
GGGTTGGTGGTCTCGCCGGTGTCGTGGTCGCACCACTGGGTGTGGGTGTTGCCGACGGTGCTGGTCACCGGCGTCCTGGG
CTGGCGGCGGCGCAACGCGGCGCTGCTGGTGCTGAGCGTCGTCGGGGTGGCCCTGATGAGGTGGACGCCCATCGACCTGC
TGCCCAAGCATCACGAGGCCAGCGCGGTGTGGTGGCGCCAGCTCGCCGGGATGTCCTACGTGTGGTGGGCGCTGGCGGTC
ATCGTCGCGGCGGGCGTCACGGTCACCGCCCGCGCCGCCTCGCGGGACGCGGCGCCGCAGCAGCTGACGCCGGTCACCGC
AATCGGCTAA

Upstream 100 bases:

>100_bases
GTGGAGCACCCTTGAAACGTACGCCAGCGCGGGTCCGGGGCGTGGGAGCCGCGCTGCAGCAGGGGTGGCGGCCTGCGCAC
CCATTACGCTGTTGTGCGAC

Downstream 100 bases:

>100_bases
CCCGCGGCCGTCTCGGGAATCCGCGCGGCCTCGCCGCCGGGTGCCTCGGCGCCGCCCTTTTTGAGGCTGGCCGCGTAGAT
GTCGACGTATTCCTGTCCCG

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-2)-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; PPM-dependent mannosyltransferase; Polyprenol-phosphate-mannose alpha-mannosyltransferase; PPM alpha-mannosyltransferase [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSTRQAPGAGFPGKRPGWALWWGLAWLTAAAALGYAAWQLFGHTPYRIDIDVYQMGARAWMDGRPLYRGDVLFHTPIVDL
PFTYPPLAAIVFCPFAWMHMPTASVAITALTLVLLVVSTVIVLARLDVWSTSALLPGPAWLRRWWLAVVVAAAATIWLEP
ISSNFAFGQINVVLMTLVIADCLPRRTPWPRGLLLGLGMALKLTPAVFLLYFLLRRDHRAVLTALASFAGATLLGFVLAY
TDSWEYWTHTVHHTDRIGSASLNTDQNIAGALARLGLAQQPRSLLWVAASLLVLAVTVWAMRRVLRADEPTLALVCVALF
GLVVSPVSWSHHWVWVLPTVLVTGVLGWRRRNAALLVLSVVGVALMRWTPIDLLPKHHEASAVWWRQLAGMSYVWWALAV
IVAAGVTVTARAASRDAAPQQLTPVTAIG

Sequences:

>Translated_429_residues
MSTRQAPGAGFPGKRPGWALWWGLAWLTAAAALGYAAWQLFGHTPYRIDIDVYQMGARAWMDGRPLYRGDVLFHTPIVDL
PFTYPPLAAIVFCPFAWMHMPTASVAITALTLVLLVVSTVIVLARLDVWSTSALLPGPAWLRRWWLAVVVAAAATIWLEP
ISSNFAFGQINVVLMTLVIADCLPRRTPWPRGLLLGLGMALKLTPAVFLLYFLLRRDHRAVLTALASFAGATLLGFVLAY
TDSWEYWTHTVHHTDRIGSASLNTDQNIAGALARLGLAQQPRSLLWVAASLLVLAVTVWAMRRVLRADEPTLALVCVALF
GLVVSPVSWSHHWVWVLPTVLVTGVLGWRRRNAALLVLSVVGVALMRWTPIDLLPKHHEASAVWWRQLAGMSYVWWALAV
IVAAGVTVTARAASRDAAPQQLTPVTAIG
>Mature_428_residues
STRQAPGAGFPGKRPGWALWWGLAWLTAAAALGYAAWQLFGHTPYRIDIDVYQMGARAWMDGRPLYRGDVLFHTPIVDLP
FTYPPLAAIVFCPFAWMHMPTASVAITALTLVLLVVSTVIVLARLDVWSTSALLPGPAWLRRWWLAVVVAAAATIWLEPI
SSNFAFGQINVVLMTLVIADCLPRRTPWPRGLLLGLGMALKLTPAVFLLYFLLRRDHRAVLTALASFAGATLLGFVLAYT
DSWEYWTHTVHHTDRIGSASLNTDQNIAGALARLGLAQQPRSLLWVAASLLVLAVTVWAMRRVLRADEPTLALVCVALFG
LVVSPVSWSHHWVWVLPTVLVTGVLGWRRRNAALLVLSVVGVALMRWTPIDLLPKHHEASAVWWRQLAGMSYVWWALAVI
VAAGVTVTARAASRDAAPQQLTPVTAIG

Specific function: Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature Lipoarabinomannan (LAM) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018584 [H]

Pfam domain/function: PF09594 DUF2029 [H]

EC number: NA

Molecular weight: Translated: 47097; Mature: 46966

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRQAPGAGFPGKRPGWALWWGLAWLTAAAALGYAAWQLFGHTPYRIDIDVYQMGARAW
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCHHHH
MDGRPLYRGDVLFHTPIVDLPFTYPPLAAIVFCPFAWMHMPTASVAITALTLVLLVVSTV
CCCCCCEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IVLARLDVWSTSALLPGPAWLRRWWLAVVVAAAATIWLEPISSNFAFGQINVVLMTLVIA
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DCLPRRTPWPRGLLLGLGMALKLTPAVFLLYFLLRRDHRAVLTALASFAGATLLGFVLAY
HHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TDSWEYWTHTVHHTDRIGSASLNTDQNIAGALARLGLAQQPRSLLWVAASLLVLAVTVWA
CCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
MRRVLRADEPTLALVCVALFGLVVSPVSWSHHWVWVLPTVLVTGVLGWRRRNAALLVLSV
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VGVALMRWTPIDLLPKHHEASAVWWRQLAGMSYVWWALAVIVAAGVTVTARAASRDAAPQ
HHHHHHHCCCHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCC
QLTPVTAIG
CCCCCCCCC
>Mature Secondary Structure 
STRQAPGAGFPGKRPGWALWWGLAWLTAAAALGYAAWQLFGHTPYRIDIDVYQMGARAW
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCHHHH
MDGRPLYRGDVLFHTPIVDLPFTYPPLAAIVFCPFAWMHMPTASVAITALTLVLLVVSTV
CCCCCCEECCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IVLARLDVWSTSALLPGPAWLRRWWLAVVVAAAATIWLEPISSNFAFGQINVVLMTLVIA
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DCLPRRTPWPRGLLLGLGMALKLTPAVFLLYFLLRRDHRAVLTALASFAGATLLGFVLAY
HHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TDSWEYWTHTVHHTDRIGSASLNTDQNIAGALARLGLAQQPRSLLWVAASLLVLAVTVWA
CCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
MRRVLRADEPTLALVCVALFGLVVSPVSWSHHWVWVLPTVLVTGVLGWRRRNAALLVLSV
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VGVALMRWTPIDLLPKHHEASAVWWRQLAGMSYVWWALAVIVAAGVTVTARAASRDAAPQ
HHHHHHHCCCHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCC
QLTPVTAIG
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]