BacMap

Definition	Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession	NC_002944
Length	4,829,781

Click here to switch to the map view.

The map label for this gene is fabG2_1

Identifier: 41407790

GI number: 41407790

Start: 1852154

End: 1852915

Strand: Direct

Name: fabG2_1

Synonym: MAP1692

Alternate gene names: 41407790

Gene position: 1852154-1852915 (Clockwise)

Preceding gene: 41407787

Following gene: 41407792

Centisome position: 38.35

GC content: 71.0

Gene sequence:

>762_bases
ATGGGACTGCTCGACCGCAAGACCGCCGTCATCACCGGCGCCAACTCCGGTATCGGGTTGGCCACCGCCGAGCGGTTCCT
GGCCGAGGGCGTCGAGCGGGTGTTCATCACGGGCCGCCGGCAACGCGAACTCGAAGACGCGGCACGGCAATTGGGGGCGC
GGGCCACCGCCGTGCGCGGCGACGTCGGGGCACCGCGCGACCTGGACCGGCTTTACGGCGAGGTGGCGGCGGCCGGCGCG
GGTCTGGACATCGTGATGGCCAACGCCGGGACGACGAGGGTGGCGCGGCTGGGCGAGATCACCGACGACGACCTCGACAC
CCTGCTTGGCACCAACGTGAAGGGCGTCGTGTACACCGTGCAGAAGGCGCTGCCGCTGCTCAACGACGGCGCCTCGATCA
TCCTGACCGGCTCCACCACCGCCGACCGCGGCCGAGCCGGGCTGAGCATCTACGCGGCCACCAAGGCCGCGGTGCGATCG
CTGGCCCGGGCCTGGGCCAACGAACTCGCCCACCGCAACATCCGGGTCAATGTCCTCGTGGCCGGGTCCACCGCCACTCC
GGGGAGCGACCGGCTGGCCGCGCAGACCGACCCCTACGTGTCCGTCGAGGAGTTCCGCGCCGGCCGGATCGCCACCATCC
CGCTGGGCCGTTTCGCCGATCCCGTCGAGATCGCCCATGCCGCAGTGTTTTTGGCCAGCGACCTGTCCAGCTTTTGCACC
GGGTCCACGGTCACCGCCGACGGCGGGTTCAACCAAGTCTGA

Upstream 100 bases:

>100_bases
GACCGCGGGGGAGCCGTGGCGGCGCCGCCCTGGCCGCGCGGCATGATCGGGAGTCGGCGACACCGGCAGGTGGGCCGCCG
CGGCAACGTCAGGAGTGTGG

Downstream 100 bases:

>100_bases
CCCCGACCACCTCACCTGCGTTGCGGCACAGGCGAATCGGCGCACAGCTAGGTCGTGGCGCCGAGGATCTTGATCGCGAA
GACCAGCGTGTCGCCGGGGC

Product: FabG2_1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MGLLDRKTAVITGANSGIGLATAERFLAEGVERVFITGRRQRELEDAARQLGARATAVRGDVGAPRDLDRLYGEVAAAGA
GLDIVMANAGTTRVARLGEITDDDLDTLLGTNVKGVVYTVQKALPLLNDGASIILTGSTTADRGRAGLSIYAATKAAVRS
LARAWANELAHRNIRVNVLVAGSTATPGSDRLAAQTDPYVSVEEFRAGRIATIPLGRFADPVEIAHAAVFLASDLSSFCT
GSTVTADGGFNQV

Sequences:

>Translated_253_residues
MGLLDRKTAVITGANSGIGLATAERFLAEGVERVFITGRRQRELEDAARQLGARATAVRGDVGAPRDLDRLYGEVAAAGA
GLDIVMANAGTTRVARLGEITDDDLDTLLGTNVKGVVYTVQKALPLLNDGASIILTGSTTADRGRAGLSIYAATKAAVRS
LARAWANELAHRNIRVNVLVAGSTATPGSDRLAAQTDPYVSVEEFRAGRIATIPLGRFADPVEIAHAAVFLASDLSSFCT
GSTVTADGGFNQV
>Mature_252_residues
GLLDRKTAVITGANSGIGLATAERFLAEGVERVFITGRRQRELEDAARQLGARATAVRGDVGAPRDLDRLYGEVAAAGAG
LDIVMANAGTTRVARLGEITDDDLDTLLGTNVKGVVYTVQKALPLLNDGASIILTGSTTADRGRAGLSIYAATKAAVRSL
ARAWANELAHRNIRVNVLVAGSTATPGSDRLAAQTDPYVSVEEFRAGRIATIPLGRFADPVEIAHAAVFLASDLSSFCTG
STVTADGGFNQV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=30.1587301587302, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=29.718875502008, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=31.3725490196078, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=30.859375, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=29.8039215686275, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=28.4584980237154, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=30.2040816326531, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=31.9371727748691, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=27.4509803921569, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=31.8681318681319, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI59889578, Length=198, Percent_Identity=33.8383838383838, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=26.3358778625954, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI4503301, Length=208, Percent_Identity=25.4807692307692, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=35.6589147286822, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=32.4110671936759, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=30.7086614173228, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=30.952380952381, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=32.4, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=31.2252964426877, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=28.5140562248996, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=27.0588235294118, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=30.4, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787820, Length=156, Percent_Identity=31.4102564102564, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=28.7937743190661, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=26.171875, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=30.6201550387597, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=30.7392996108949, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17562908, Length=256, Percent_Identity=29.6875, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=30.4347826086957, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=258, Percent_Identity=29.4573643410853, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=28.515625, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=30.2681992337165, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=28.2352941176471, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=28.6259541984733, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=256, Percent_Identity=28.515625, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=28.5171102661597, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=257, Percent_Identity=28.0155642023346, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=29.296875, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=29.4820717131474, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=28.7937743190661, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=29.9242424242424, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=29.8039215686275, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=28.2352941176471, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=30.6201550387597, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=29.9242424242424, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=28.6792452830189, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=29.277566539924, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=29.5454545454545, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=28.6259541984733, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=28.4090909090909, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=27.5510204081633, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=31.3008130081301, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=30.859375, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=30.6451612903226, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=31.8548387096774, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=32.9457364341085, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=30.3149606299213, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=29.9212598425197, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI116007238, Length=217, Percent_Identity=27.6497695852535, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26308; Mature: 26177

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLDRKTAVITGANSGIGLATAERFLAEGVERVFITGRRQRELEDAARQLGARATAVRG
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCHHEEECC
DVGAPRDLDRLYGEVAAAGAGLDIVMANAGTTRVARLGEITDDDLDTLLGTNVKGVVYTV
CCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCHHHHHHHCCCCCHHHHHH
QKALPLLNDGASIILTGSTTADRGRAGLSIYAATKAAVRSLARAWANELAHRNIRVNVLV
HHHHHHCCCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
AGSTATPGSDRLAAQTDPYVSVEEFRAGRIATIPLGRFADPVEIAHAAVFLASDLSSFCT
ECCCCCCCCCCCCCCCCCCEEHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
GSTVTADGGFNQV
CCEEEECCCCCCC
>Mature Secondary Structure 
GLLDRKTAVITGANSGIGLATAERFLAEGVERVFITGRRQRELEDAARQLGARATAVRG
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCHHEEECC
DVGAPRDLDRLYGEVAAAGAGLDIVMANAGTTRVARLGEITDDDLDTLLGTNVKGVVYTV
CCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCHHHHHHHCCCCCHHHHHH
QKALPLLNDGASIILTGSTTADRGRAGLSIYAATKAAVRSLARAWANELAHRNIRVNVLV
HHHHHHCCCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
AGSTATPGSDRLAAQTDPYVSVEEFRAGRIATIPLGRFADPVEIAHAAVFLASDLSSFCT
ECCCCCCCCCCCCCCCCCCEEHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHC
GSTVTADGGFNQV
CCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]