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The map label for this gene is zwf [H]

Identifier: 41407785

GI number: 41407785

Start: 1845601

End: 1848054

Strand: Direct

Name: zwf [H]

Synonym: MAP1687

Alternate gene names: 41407785

Gene position: 1845601-1848054 (Clockwise)

Preceding gene: 41407784

Following gene: 41407786

Centisome position: 38.21

GC content: 66.46

Gene sequence:

>2454_bases
GTGGCTACCCAGAAACCGCAGACCATCTCCTACCCGGCTCCCGAGGCCCGGCCGCGTCGTCACCACACCGACCCGCTCGA
CCCTCATGTGATCGTCCTGTTCGGCGCCACCGGGGATTTGGCGAAACGCAAGCTGATCCCCGGTTTGGCGTATCTGGACC
AGTCCGAGCTGGCACCCGACATCCAGATCGTCGCCACGTCGCTGGAGGACCTGAGCAACGACGAATTCCGCGAGCTGGCC
AAGAACGCGATCGACTCGTTCGGCACGCACAAGCTGACGCCCGACCAGTGGCGCAACTTCGCCGACATCATCACCTACAT
CCCGCAGAGCGCCGGCTCCGACGCGCTGGCCGCCGCGGTGGCCGAGGCCGAGGCCAAGCTGGGGCCGAACGTGCGGCGGC
TGCATTACCTGTCGGTGCCGCCGAAGGCGGCGCGCGCGGTGATCACCATGCTGCGCGACGCCAAACTGGTCGAGCGGTCG
CGGGTGGTGATGGAGAAACCGTTCGGCACCGATCTGGCCAGCGCGGTGGCGCTCAACGACTTCGTGCACCAAACCTTCGA
GGAATCCCAGATTTTCCGCATCGACCACTTCCTGGGTAAGGAGGCCGCCCAGAACATTCTGGCGTTCCGCTTCGCCAACG
GGTTGTTCGAGCCGATCTGGAACCGCAACTTCATCGACCACATCCAAATCGACATCCCCGAGGCCCTCGGCCTGGATCAG
CGGGCGAGTTTCTACGAGGAGACCGGCGCCTACAAGGACATGGTGGTCACCCATCTGTTTCAGGTGATGGCCTTCGTGGT
GATGGAGCCGCCGACGGCGCTCGAACCGTTCGCCATCAGCGAAGAAAAGAACAAGGTGTTCCGGTCGATGCTTCCGGTCA
AGCCCTCGAACGTGGTTCGCGGTCAGTACATCGGCTATCGCGAGGAAGACGGAGTGGCAAAGGATTCCGACACCGAGACA
TTCATCGCCCTCAAGGTCGGCATCGACAACTGGCGGTGGGCCGGGGTGCCCGTCTACCTTCGCACCGGTAAGAGGATGGC
CGAGGGCATCCGGCATCATCTCGATCGCGTTCAAGGAGGCACCGCGGACCATGTTCCCGCCCGGGTCGGGGGTGGGCACG
CAGGGGCCCGACCACCTGACGTTCGATCTTGCGGACAATTCGCGGGTGTCGCTGTCGTTCTACGGCAAGCGGCCCGGCCC
CGGCATGAAACTGGACAAGCTGTCCATGCAATTCTCCACCCAGGAGATCGAAACCGCGGTGGACGTGCTGGAGGTCTACG
AACGGCTCATCCTGGACGCGATGCGCGGCGACCACACCCTGTTCACCACCGCCGAAGGCATCGAATCACTGTGGGAGCGT
TCCGAAGAGCTGCTCAACGACCCGCCACCGGCCAAGCTGTACCAGCCGGGGACGTGGGGCCCCAACGCAATTCACCAGTT
GATCGCGCCCAACGCGTGGCGGCTGCCGTTCGAGCGCGAGTGGCGCGATCCCCAGACCCTACCCCGGAGTGGGCAGCTGA
GAAGTGCTGCGGTTCAGCCCAATTCGGCGCTGAGATAACTGATGGCCTGGCGGAATTCCCTGAGGATTTCGTTGTCGGGC
AACTCGAAGCCGTAGTCGGTGTACACCCGCTCGGTGGGCAGGCGGGTGACGCTCCAGCCGGTGGCCTCCAGGTGGTCGCC
GGCCGGGCGGCGCTCGCCGAGCCAGACCAGTTCGGCCACGTCGATGTCCAGTCCGTGCTGGCGCCAGGTGCTGCGCATCG
CCCGGGCGCGTTCGTCGGTGAACACCCGCATGTCGGTGATGTTCTCGGTGGCCAGCCTGCTGCCCGGCGCGCTGAGCGCG
GTGATGTTGTCCAGCAGCCGGTCCTGGGCGTGCGGCGGCAGGTAGGGCAGCAGCCCCTCGGCGATCCAGGCGGTACGGGC
GCTGCTGTCAAAGCCGTTGTCGCGCAACGCTGTTGGCCAGTCATCGCGCAAATCGACGGCGACGGTGCGGCGCTCGGCGG
TCGGTTGCGCGCCCAGCCGGGCCAGGGTGTCGGTCTTGAAGGAGATGACCTCGGGCTGGTCGACCTCGAACACCACGGTG
CCCGCCGGCCAGGACAACCGGTAGGCCCGCGCGTCGAGCCCGGCGGCCAGGATGACGGCCTGGCGAATGCCGGCAGCGGT
CGCGGAGCGGAAGAAATCGTCGAAAAACCGCGTCCGCACCGTGATTTGCTCGCGCCGCTGCTGCAGCGTCATCGGCATGT
CGTCGGTGTCGAGCGGGATCTGGCCGTCCAGCATCCGGACGAAGAAGGGATGCCCGACCGCGCGCACCAACGGTTCGGCG
AACCGGTCGTCGAGCAGCGGGTCCGGACCGCGAGAGGCCAGCGCCCGGGAGGCCGCGACCATGGTCGCGGTCGCCCCCAC
GCTGGAGGCCAGATCCCAGCTGTCGCCCTCGGTACGTGCCGAACCGGTCGATGA

Upstream 100 bases:

>100_bases
GCCCAGGCGTGGGCAGCCCGCCGGTATCCAGTACCCGATCGTAGGACCGCTAACCCGAGCAGGCGCGACACGGCAGCGCG
GCGATGGAAGTATCGCAGGG

Downstream 100 bases:

>100_bases
CATCTGTTCTCCCCTTCCGCGATCCGGCCGCCGCGGGACCGATTGGCCCCCGGCCCGGTCGCCACCCGCGACTACACCGC
CGGTATCGAAGGGTACTTTC

Product: hypothetical protein

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 817; Mature: 816

Protein sequence:

>817_residues
MATQKPQTISYPAPEARPRRHHTDPLDPHVIVLFGATGDLAKRKLIPGLAYLDQSELAPDIQIVATSLEDLSNDEFRELA
KNAIDSFGTHKLTPDQWRNFADIITYIPQSAGSDALAAAVAEAEAKLGPNVRRLHYLSVPPKAARAVITMLRDAKLVERS
RVVMEKPFGTDLASAVALNDFVHQTFEESQIFRIDHFLGKEAAQNILAFRFANGLFEPIWNRNFIDHIQIDIPEALGLDQ
RASFYEETGAYKDMVVTHLFQVMAFVVMEPPTALEPFAISEEKNKVFRSMLPVKPSNVVRGQYIGYREEDGVAKDSDTET
FIALKVGIDNWRWAGVPVYLRTGKRMAEGIRHHLDRVQGGTADHVPARVGGGHAGARPPDVRSCGQFAGVAVVLRQAARP
RHETGQAVHAILHPGDRNRGGRAGGLRTAHPGRDARRPHPVHHRRRHRITVGAFRRAAQRPATGQAVPAGDVGPQRNSPV
DRAQRVAAAVRARVARSPDPTPEWAAEKCCGSAQFGAEITDGLAEFPEDFVVGQLEAVVGVHPLGGQAGDAPAGGLQVVA
GRAALAEPDQFGHVDVQSVLAPGAAHRPGAFVGEHPHVGDVLGGQPAARRAERGDVVQQPVLGVRRQVGQQPLGDPGGTG
AAVKAVVAQRCWPVIAQIDGDGAALGGRLRAQPGQGVGLEGDDLGLVDLEHHGARRPGQPVGPRVEPGGQDDGLANAGSG
RGAEEIVEKPRPHRDLLAPLLQRHRHVVGVERDLAVQHPDEEGMPDRAHQRFGEPVVEQRVRTARGQRPGGRDHGRGRPH
AGGQIPAVALGTCRTGR

Sequences:

>Translated_817_residues
MATQKPQTISYPAPEARPRRHHTDPLDPHVIVLFGATGDLAKRKLIPGLAYLDQSELAPDIQIVATSLEDLSNDEFRELA
KNAIDSFGTHKLTPDQWRNFADIITYIPQSAGSDALAAAVAEAEAKLGPNVRRLHYLSVPPKAARAVITMLRDAKLVERS
RVVMEKPFGTDLASAVALNDFVHQTFEESQIFRIDHFLGKEAAQNILAFRFANGLFEPIWNRNFIDHIQIDIPEALGLDQ
RASFYEETGAYKDMVVTHLFQVMAFVVMEPPTALEPFAISEEKNKVFRSMLPVKPSNVVRGQYIGYREEDGVAKDSDTET
FIALKVGIDNWRWAGVPVYLRTGKRMAEGIRHHLDRVQGGTADHVPARVGGGHAGARPPDVRSCGQFAGVAVVLRQAARP
RHETGQAVHAILHPGDRNRGGRAGGLRTAHPGRDARRPHPVHHRRRHRITVGAFRRAAQRPATGQAVPAGDVGPQRNSPV
DRAQRVAAAVRARVARSPDPTPEWAAEKCCGSAQFGAEITDGLAEFPEDFVVGQLEAVVGVHPLGGQAGDAPAGGLQVVA
GRAALAEPDQFGHVDVQSVLAPGAAHRPGAFVGEHPHVGDVLGGQPAARRAERGDVVQQPVLGVRRQVGQQPLGDPGGTG
AAVKAVVAQRCWPVIAQIDGDGAALGGRLRAQPGQGVGLEGDDLGLVDLEHHGARRPGQPVGPRVEPGGQDDGLANAGSG
RGAEEIVEKPRPHRDLLAPLLQRHRHVVGVERDLAVQHPDEEGMPDRAHQRFGEPVVEQRVRTARGQRPGGRDHGRGRPH
AGGQIPAVALGTCRTGR
>Mature_816_residues
ATQKPQTISYPAPEARPRRHHTDPLDPHVIVLFGATGDLAKRKLIPGLAYLDQSELAPDIQIVATSLEDLSNDEFRELAK
NAIDSFGTHKLTPDQWRNFADIITYIPQSAGSDALAAAVAEAEAKLGPNVRRLHYLSVPPKAARAVITMLRDAKLVERSR
VVMEKPFGTDLASAVALNDFVHQTFEESQIFRIDHFLGKEAAQNILAFRFANGLFEPIWNRNFIDHIQIDIPEALGLDQR
ASFYEETGAYKDMVVTHLFQVMAFVVMEPPTALEPFAISEEKNKVFRSMLPVKPSNVVRGQYIGYREEDGVAKDSDTETF
IALKVGIDNWRWAGVPVYLRTGKRMAEGIRHHLDRVQGGTADHVPARVGGGHAGARPPDVRSCGQFAGVAVVLRQAARPR
HETGQAVHAILHPGDRNRGGRAGGLRTAHPGRDARRPHPVHHRRRHRITVGAFRRAAQRPATGQAVPAGDVGPQRNSPVD
RAQRVAAAVRARVARSPDPTPEWAAEKCCGSAQFGAEITDGLAEFPEDFVVGQLEAVVGVHPLGGQAGDAPAGGLQVVAG
RAALAEPDQFGHVDVQSVLAPGAAHRPGAFVGEHPHVGDVLGGQPAARRAERGDVVQQPVLGVRRQVGQQPLGDPGGTGA
AVKAVVAQRCWPVIAQIDGDGAALGGRLRAQPGQGVGLEGDDLGLVDLEHHGARRPGQPVGPRVEPGGQDDGLANAGSGR
GAEEIVEKPRPHRDLLAPLLQRHRHVVGVERDLAVQHPDEEGMPDRAHQRFGEPVVEQRVRTARGQRPGGRDHGRGRPHA
GGQIPAVALGTCRTGR

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI109389365, Length=341, Percent_Identity=33.4310850439883, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI108773793, Length=341, Percent_Identity=33.4310850439883, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI52145310, Length=351, Percent_Identity=33.9031339031339, Blast_Score=145, Evalue=1e-34,
Organism=Escherichia coli, GI1788158, Length=333, Percent_Identity=39.6396396396396, Blast_Score=250, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17538218, Length=356, Percent_Identity=34.2696629213483, Blast_Score=202, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6324088, Length=358, Percent_Identity=33.5195530726257, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24643350, Length=377, Percent_Identity=32.3607427055703, Blast_Score=189, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24643352, Length=346, Percent_Identity=32.6589595375723, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI221513548, Length=346, Percent_Identity=28.9017341040462, Blast_Score=134, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 87949; Mature: 87818

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQKPQTISYPAPEARPRRHHTDPLDPHVIVLFGATGDLAKRKLIPGLAYLDQSELAPD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCHHHCCHHHCCCC
IQIVATSLEDLSNDEFRELAKNAIDSFGTHKLTPDQWRNFADIITYIPQSAGSDALAAAV
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
AEAEAKLGPNVRRLHYLSVPPKAARAVITMLRDAKLVERSRVVMEKPFGTDLASAVALND
HHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
FVHQTFEESQIFRIDHFLGKEAAQNILAFRFANGLFEPIWNRNFIDHIQIDIPEALGLDQ
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHCCCH
RASFYEETGAYKDMVVTHLFQVMAFVVMEPPTALEPFAISEEKNKVFRSMLPVKPSNVVR
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
GQYIGYREEDGVAKDSDTETFIALKVGIDNWRWAGVPVYLRTGKRMAEGIRHHLDRVQGG
CCCCCEECCCCCCCCCCCCEEEEEEECCCCCEECCEEEEECCCHHHHHHHHHHHHHHCCC
TADHVPARVGGGHAGARPPDVRSCGQFAGVAVVLRQAARPRHETGQAVHAILHPGDRNRG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
GRAGGLRTAHPGRDARRPHPVHHRRRHRITVGAFRRAAQRPATGQAVPAGDVGPQRNSPV
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
DRAQRVAAAVRARVARSPDPTPEWAAEKCCGSAQFGAEITDGLAEFPEDFVVGQLEAVVG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHC
VHPLGGQAGDAPAGGLQVVAGRAALAEPDQFGHVDVQSVLAPGAAHRPGAFVGEHPHVGD
CCCCCCCCCCCCCCCCEEEECCHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCC
VLGGQPAARRAERGDVVQQPVLGVRRQVGQQPLGDPGGTGAAVKAVVAQRCWPVIAQIDG
CCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECC
DGAALGGRLRAQPGQGVGLEGDDLGLVDLEHHGARRPGQPVGPRVEPGGQDDGLANAGSG
CCCCCCCEEECCCCCCCCCCCCCCCEEECHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RGAEEIVEKPRPHRDLLAPLLQRHRHVVGVERDLAVQHPDEEGMPDRAHQRFGEPVVEQR
CCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHCCHHHHHH
VRTARGQRPGGRDHGRGRPHAGGQIPAVALGTCRTGR
HHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
ATQKPQTISYPAPEARPRRHHTDPLDPHVIVLFGATGDLAKRKLIPGLAYLDQSELAPD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCHHHCCHHHCCCC
IQIVATSLEDLSNDEFRELAKNAIDSFGTHKLTPDQWRNFADIITYIPQSAGSDALAAAV
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
AEAEAKLGPNVRRLHYLSVPPKAARAVITMLRDAKLVERSRVVMEKPFGTDLASAVALND
HHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
FVHQTFEESQIFRIDHFLGKEAAQNILAFRFANGLFEPIWNRNFIDHIQIDIPEALGLDQ
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHCCCH
RASFYEETGAYKDMVVTHLFQVMAFVVMEPPTALEPFAISEEKNKVFRSMLPVKPSNVVR
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
GQYIGYREEDGVAKDSDTETFIALKVGIDNWRWAGVPVYLRTGKRMAEGIRHHLDRVQGG
CCCCCEECCCCCCCCCCCCEEEEEEECCCCCEECCEEEEECCCHHHHHHHHHHHHHHCCC
TADHVPARVGGGHAGARPPDVRSCGQFAGVAVVLRQAARPRHETGQAVHAILHPGDRNRG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCC
GRAGGLRTAHPGRDARRPHPVHHRRRHRITVGAFRRAAQRPATGQAVPAGDVGPQRNSPV
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
DRAQRVAAAVRARVARSPDPTPEWAAEKCCGSAQFGAEITDGLAEFPEDFVVGQLEAVVG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHC
VHPLGGQAGDAPAGGLQVVAGRAALAEPDQFGHVDVQSVLAPGAAHRPGAFVGEHPHVGD
CCCCCCCCCCCCCCCCEEEECCHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCC
VLGGQPAARRAERGDVVQQPVLGVRRQVGQQPLGDPGGTGAAVKAVVAQRCWPVIAQIDG
CCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECC
DGAALGGRLRAQPGQGVGLEGDDLGLVDLEHHGARRPGQPVGPRVEPGGQDDGLANAGSG
CCCCCCCEEECCCCCCCCCCCCCCCEEECHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RGAEEIVEKPRPHRDLLAPLLQRHRHVVGVERDLAVQHPDEEGMPDRAHQRFGEPVVEQR
CCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHCCHHHHHH
VRTARGQRPGGRDHGRGRPHAGGQIPAVALGTCRTGR
HHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]