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The map label for this gene is ribH

Identifier: 41407239

GI number: 41407239

Start: 1195960

End: 1196442

Strand: Direct

Name: ribH

Synonym: MAP1141

Alternate gene names: 41407239

Gene position: 1195960-1196442 (Clockwise)

Preceding gene: 41407238

Following gene: 41407240

Centisome position: 24.76

GC content: 71.64

Gene sequence:

>483_bases
ATGAGTCCAGCCGCCGGCGTGCCGGAGATGCCGGCGCTCGACGCGTCCGGCGTGCGGCTGGGCATCGTGGCGAGCACCTG
GCACAGTCGGATCTGTGACGCGCTGCTGGCCGGTGCCCGCAAAGTCGCCGCCGACTCGGGAGTCGACAACCCCACGGTGG
TCCGCGTGCTCGGTGCCATCGAAATCCCGGTGGTCGCACAGGAACTCGCCCGCAACCACGACGCGGTCGTCGCGTTGGGC
GTCGTGATCCGCGGGCAGACACCGCATTTCGAGTACGTCTGCGACGCCGTCACCCAGGGCATCACCCGGGTTTCGCTGGA
CGCGTCGACGCCGGTCGCCAACGGCGTGCTGACCACCGACAACGAGCAGCAGGCGCTGGACCGGGCCGGGCTGCCGGAAT
CGGCCGAGGACAAGGGGTCGCAGGCGGCCGGGGCGGCGCTGTCCGCCGCGCTCACCCTGCGTGAGTTGCGCGCTCGGTCG
TGA

Upstream 100 bases:

>100_bases
GATTTTCACGAATCGGTCCATCTGCCAGGCGAATTCGGCGGCGCCCTGTGAGTCGCGCCGGCGACGATGCAGAGCGAAGC
GATGAGGAGGAGTGGCGCCC

Downstream 100 bases:

>100_bases
CCCCGCCGGAACCCGAACGCTGGGATGTGGTGCTGCGTCCGCACCGCACCCCGTTATTCGTCTACGGGGCAGCGGTTCTC
ATCGCCGCTGCGCACATCGC

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSPAAGVPEMPALDASGVRLGIVASTWHSRICDALLAGARKVAADSGVDNPTVVRVLGAIEIPVVAQELARNHDAVVALG
VVIRGQTPHFEYVCDAVTQGITRVSLDASTPVANGVLTTDNEQQALDRAGLPESAEDKGSQAAGAALSAALTLRELRARS

Sequences:

>Translated_160_residues
MSPAAGVPEMPALDASGVRLGIVASTWHSRICDALLAGARKVAADSGVDNPTVVRVLGAIEIPVVAQELARNHDAVVALG
VVIRGQTPHFEYVCDAVTQGITRVSLDASTPVANGVLTTDNEQQALDRAGLPESAEDKGSQAAGAALSAALTLRELRARS
>Mature_159_residues
SPAAGVPEMPALDASGVRLGIVASTWHSRICDALLAGARKVAADSGVDNPTVVRVLGAIEIPVVAQELARNHDAVVALGV
VIRGQTPHFEYVCDAVTQGITRVSLDASTPVANGVLTTDNEQQALDRAGLPESAEDKGSQAAGAALSAALTLRELRARS

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=145, Percent_Identity=42.7586206896552, Blast_Score=97, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324429, Length=152, Percent_Identity=33.5526315789474, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16415; Mature: 16284

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAAGVPEMPALDASGVRLGIVASTWHSRICDALLAGARKVAADSGVDNPTVVRVLGAI
CCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
EIPVVAQELARNHDAVVALGVVIRGQTPHFEYVCDAVTQGITRVSLDASTPVANGVLTTD
CCHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCCCCCCCEEECC
NEQQALDRAGLPESAEDKGSQAAGAALSAALTLRELRARS
CHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SPAAGVPEMPALDASGVRLGIVASTWHSRICDALLAGARKVAADSGVDNPTVVRVLGAI
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
EIPVVAQELARNHDAVVALGVVIRGQTPHFEYVCDAVTQGITRVSLDASTPVANGVLTTD
CCHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCCCCCCCEEECC
NEQQALDRAGLPESAEDKGSQAAGAALSAALTLRELRARS
CHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA