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The map label for this gene is aroF

Identifier: 41407189

GI number: 41407189

Start: 1144613

End: 1145827

Strand: Direct

Name: aroF

Synonym: MAP1091

Alternate gene names: 41407189

Gene position: 1144613-1145827 (Clockwise)

Preceding gene: 41407188

Following gene: 41407190

Centisome position: 23.7

GC content: 75.23

Gene sequence:

>1215_bases
ATGGGACCCGTGTTGCGTTGGATCACCGCCGGGGAGTCGCATGGCCGCGCGCTGGTGGCCGTGCTGGAAGGCATGGTCGC
CGGGGTGGAGATCACCTCCACCGACATCTCCGAACAGTTGGCCCGGCGCCGCCTCGGGTACGGCCGCGGCGCCCGGATGA
GCTTCGAGCGGGACGCGGTGAGCGTGCTGTCCGGGGTGCGGCACGGCCTCACCCTGGGCGGACCGATCGCCGTCGAGATC
GGCAACACCGAATGGCCCAAGTGGGAAACCGTGATGGCCACCGACCCGGTCGACCCGGCGCAGCTGGCCGACAGCGCCCG
CAACGCCCCGCTCACCCGGCCGCGGCCCGGCCACGCCGACTACGCCGGCATGCTCAAGTACGGGTTCGACGACGCCCGGC
CGGTGCTGGAGCGGGCCAGCGCCCGCGAGACCGCGGCGCGGGTGGCCGCGGGCACCATCGCCCGGTCGTTCCTGCGCCAG
GCGCTCGGCGTCGAGGTGCTCTCGCACGTGATCGCGATCGGCCCGTCGGCGCCGTACGAAGGGCCGCCCCCGGGCCCGGG
CGACCTGCCCGCGATCGACGCCAGCCCGGTGCGCGCCTACGACGAGGCGGCGGAACAGGCGATGATCGCCGAGATCGAGG
CCGCCAAGAAGGACGGCGACACCCTGGGCGGCGTGGTCGAGGTGGTGGCGCTGGGGCTGCCCGTCGGGCTGGGCTCGTTC
ACCAGCGGCGACAACCGGCTGGACGGCCAGCTGGCCGCCGCGGTGATGGGCATCCAGGCGATCAAGGGGGTGGAGATCGG
CGACGGTTTCGCCACCGCCCGCCGCCGCGGCAGCCAGGCCCACGACGAGATGTACCCCGGCCCCGACGGCGTGGTCCGCT
CGACCAACCGGGCCGGCGGGCTGGAGGGCGGCATGACCAACGGCCAGCCGCTGCGGGTGCGCGCCGCGATGAAGCCGATC
TCCACCGTGCCGCGGGCGCTGGCCACCGTCGACATGGCCACCGGCGACGAGGCCGTCGCCATCCACCAGCGCTCGGACGT
GTGCGCGGTGCCGGCCGCCGGGGTGGTGGTCGAGGCCATGGTGGCGCTGGTGCTGGCCCGCGCGACGCTGCAGAAGTTCG
GCGGCGACTCGCTGGCCGAGACCCGCCGCAACATCGACGCCTACCGGCGGGCGGTCGCCGAGCGCGAGGCGCCGGCCGCC
CGGGGAACCGCGTGA

Upstream 100 bases:

>100_bases
CGACGCGGTCCCGGGCCGGCGGCTGGCGCATCCGGCGCTGTCCCCCTCCTGAACGTGGGGGGCCTGCGCGAATCGGCCTT
TCGGAACTCGACATGGGAAG

Downstream 100 bases:

>100_bases
TGGCGCCCAAAGCGGTGCTGATCGGGCTGCCGGGCTCCGGCAAGTCCACCATCGGGCGGCGGCTGGCCAAGGCGCTCGGG
GTGGGTTTCCTGGACACCGA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MGPVLRWITAGESHGRALVAVLEGMVAGVEITSTDISEQLARRRLGYGRGARMSFERDAVSVLSGVRHGLTLGGPIAVEI
GNTEWPKWETVMATDPVDPAQLADSARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTIARSFLRQ
ALGVEVLSHVIAIGPSAPYEGPPPGPGDLPAIDASPVRAYDEAAEQAMIAEIEAAKKDGDTLGGVVEVVALGLPVGLGSF
TSGDNRLDGQLAAAVMGIQAIKGVEIGDGFATARRRGSQAHDEMYPGPDGVVRSTNRAGGLEGGMTNGQPLRVRAAMKPI
STVPRALATVDMATGDEAVAIHQRSDVCAVPAAGVVVEAMVALVLARATLQKFGGDSLAETRRNIDAYRRAVAEREAPAA
RGTA

Sequences:

>Translated_404_residues
MGPVLRWITAGESHGRALVAVLEGMVAGVEITSTDISEQLARRRLGYGRGARMSFERDAVSVLSGVRHGLTLGGPIAVEI
GNTEWPKWETVMATDPVDPAQLADSARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTIARSFLRQ
ALGVEVLSHVIAIGPSAPYEGPPPGPGDLPAIDASPVRAYDEAAEQAMIAEIEAAKKDGDTLGGVVEVVALGLPVGLGSF
TSGDNRLDGQLAAAVMGIQAIKGVEIGDGFATARRRGSQAHDEMYPGPDGVVRSTNRAGGLEGGMTNGQPLRVRAAMKPI
STVPRALATVDMATGDEAVAIHQRSDVCAVPAAGVVVEAMVALVLARATLQKFGGDSLAETRRNIDAYRRAVAEREAPAA
RGTA
>Mature_403_residues
GPVLRWITAGESHGRALVAVLEGMVAGVEITSTDISEQLARRRLGYGRGARMSFERDAVSVLSGVRHGLTLGGPIAVEIG
NTEWPKWETVMATDPVDPAQLADSARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTIARSFLRQA
LGVEVLSHVIAIGPSAPYEGPPPGPGDLPAIDASPVRAYDEAAEQAMIAEIEAAKKDGDTLGGVVEVVALGLPVGLGSFT
SGDNRLDGQLAAAVMGIQAIKGVEIGDGFATARRRGSQAHDEMYPGPDGVVRSTNRAGGLEGGMTNGQPLRVRAAMKPIS
TVPRALATVDMATGDEAVAIHQRSDVCAVPAAGVVVEAMVALVLARATLQKFGGDSLAETRRNIDAYRRAVAEREAPAAR
GTA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=372, Percent_Identity=36.0215053763441, Blast_Score=172, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6321290, Length=380, Percent_Identity=34.2105263157895, Blast_Score=174, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_MYCPA (Q741J9)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_960025.1
- ProteinModelPortal:   Q741J9
- SMR:   Q741J9
- EnsemblBacteria:   EBMYCT00000036667
- GeneID:   2720000
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP1091
- NMPDR:   fig|262316.1.peg.1091
- GeneTree:   EBGT00050000016560
- HOGENOM:   HBG292336
- OMA:   GSEAHDE
- ProtClustDB:   PRK05382
- BRENDA:   4.2.3.5
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 42014; Mature: 41883

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPVLRWITAGESHGRALVAVLEGMVAGVEITSTDISEQLARRRLGYGRGARMSFERDAV
CCCCEEEEECCCCCCHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SVLSGVRHGLTLGGPIAVEIGNTEWPKWETVMATDPVDPAQLADSARNAPLTRPRPGHAD
HHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCC
YAGMLKYGFDDARPVLERASARETAARVAAGTIARSFLRQALGVEVLSHVIAIGPSAPYE
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GPPPGPGDLPAIDASPVRAYDEAAEQAMIAEIEAAKKDGDTLGGVVEVVALGLPVGLGSF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
TSGDNRLDGQLAAAVMGIQAIKGVEIGDGFATARRRGSQAHDEMYPGPDGVVRSTNRAGG
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHCCCCCCCCCEECCCCCCC
LEGGMTNGQPLRVRAAMKPISTVPRALATVDMATGDEAVAIHQRSDVCAVPAAGVVVEAM
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEECCCHHHHHHHHH
VALVLARATLQKFGGDSLAETRRNIDAYRRAVAEREAPAARGTA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GPVLRWITAGESHGRALVAVLEGMVAGVEITSTDISEQLARRRLGYGRGARMSFERDAV
CCCEEEEECCCCCCHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHH
SVLSGVRHGLTLGGPIAVEIGNTEWPKWETVMATDPVDPAQLADSARNAPLTRPRPGHAD
HHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCC
YAGMLKYGFDDARPVLERASARETAARVAAGTIARSFLRQALGVEVLSHVIAIGPSAPYE
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GPPPGPGDLPAIDASPVRAYDEAAEQAMIAEIEAAKKDGDTLGGVVEVVALGLPVGLGSF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
TSGDNRLDGQLAAAVMGIQAIKGVEIGDGFATARRRGSQAHDEMYPGPDGVVRSTNRAGG
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHCCCCCCCCCEECCCCCCC
LEGGMTNGQPLRVRAAMKPISTVPRALATVDMATGDEAVAIHQRSDVCAVPAAGVVVEAM
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEECCCHHHHHHHHH
VALVLARATLQKFGGDSLAETRRNIDAYRRAVAEREAPAARGTA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA