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The map label for this gene is aroE

Identifier: 41407178

GI number: 41407178

Start: 1133568

End: 1134398

Strand: Direct

Name: aroE

Synonym: MAP1080

Alternate gene names: 41407178

Gene position: 1133568-1134398 (Clockwise)

Preceding gene: 41407177

Following gene: 41407179

Centisome position: 23.47

GC content: 75.45

Gene sequence:

>831_bases
GTGTCCTCGACAGCACCCCCCGCTAGCGCGGGGCCCCGCAGGGCGGCCGTGCTGGGCAAGCCGATCGGCCACTCGAAATC
CCCGCAGCTGCACCTGGCCGCCTACCGTGCGCTGGGCCTGCACGACTGGACCTACGAGCGCATCGAATGCGACGCCGACC
AGCTGCCCGGCGTGGTCGGCGGGTTCGGCCCCGAGTGGGTCGGGGTGTCGGTGACCATGCCCGGCAAATTCGCGGCGCTG
CGCTTCGCCGACGAGCGCACCGAGCAGGCGCGGCGGGTGGGATCGGCCAACACCCTGGTGCGCACCGCGACGGGCTGGCG
GGCCGACAACACCGACATCGACGGCGTCGCCGGCGCGCTGGGCGCCGCTTCGGGATGGGCGCTGGTCTGTGGATCGGGCG
GCACCGCGCCGGCGGCCGTCGCGGGCCTGGCCCAGCTGGGCGTCGCCGGCATCACCGTGGTGGCCCGCAACCCCGACAAG
GCGGCCCGGCTGGTGCGCCTCGGCGACGAGCTGGGCGTGCCGACCCGGTTCTGCGCCCTGGACGGCGCTGGGCTGGCCGA
CGAGGTGGCCGCGGCCGAGGTGCTGGTCAGCACCCTGCCGGCGGAGGTGGCCGAACGCTATGCCGGCACCTTGGCGCGCG
TCGGCGTGCTGCTCGACGCCGTCTACGACCCCTGGCCCACCCCGCTGGCCGCCGCGGTGAGCGCCGCCGGCGGCCGGGTG
ATCAGCGGCATGCAGATGCTGCTGCACCAGGCCTTCGCCCAGGTGGAACAGTTCACCGGGCTGCCCGCCCCGCGCGAAGC
GATGACTTGCGCGGCGGCCGACGCGGATTAG

Upstream 100 bases:

>100_bases
GACTGGCTCTACTTCGTCACCATCGACGCCGCCGGGACGACGCTGTTCACCAAGGACTATCAGCAGCACCTGGCCAACAT
CGAGCTGGCTAAGCACAACG

Downstream 100 bases:

>100_bases
CATGCCGCGCATGCGAATTGCGGCCGCGGGCGCGGTGCTGACCTGGCTGGCGGTGTTGAGCTGCTACGACATCCGGCAAC
ACCGGCTGCCCAACGCACTG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSSTAPPASAGPRRAAVLGKPIGHSKSPQLHLAAYRALGLHDWTYERIECDADQLPGVVGGFGPEWVGVSVTMPGKFAAL
RFADERTEQARRVGSANTLVRTATGWRADNTDIDGVAGALGAASGWALVCGSGGTAPAAVAGLAQLGVAGITVVARNPDK
AARLVRLGDELGVPTRFCALDGAGLADEVAAAEVLVSTLPAEVAERYAGTLARVGVLLDAVYDPWPTPLAAAVSAAGGRV
ISGMQMLLHQAFAQVEQFTGLPAPREAMTCAAADAD

Sequences:

>Translated_276_residues
MSSTAPPASAGPRRAAVLGKPIGHSKSPQLHLAAYRALGLHDWTYERIECDADQLPGVVGGFGPEWVGVSVTMPGKFAAL
RFADERTEQARRVGSANTLVRTATGWRADNTDIDGVAGALGAASGWALVCGSGGTAPAAVAGLAQLGVAGITVVARNPDK
AARLVRLGDELGVPTRFCALDGAGLADEVAAAEVLVSTLPAEVAERYAGTLARVGVLLDAVYDPWPTPLAAAVSAAGGRV
ISGMQMLLHQAFAQVEQFTGLPAPREAMTCAAADAD
>Mature_275_residues
SSTAPPASAGPRRAAVLGKPIGHSKSPQLHLAAYRALGLHDWTYERIECDADQLPGVVGGFGPEWVGVSVTMPGKFAALR
FADERTEQARRVGSANTLVRTATGWRADNTDIDGVAGALGAASGWALVCGSGGTAPAAVAGLAQLGVAGITVVARNPDKA
ARLVRLGDELGVPTRFCALDGAGLADEVAAAEVLVSTLPAEVAERYAGTLARVGVLLDAVYDPWPTPLAAAVSAAGGRVI
SGMQMLLHQAFAQVEQFTGLPAPREAMTCAAADAD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=275, Percent_Identity=29.0909090909091, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320332, Length=285, Percent_Identity=31.5789473684211, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 28132; Mature: 28001

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTAPPASAGPRRAAVLGKPIGHSKSPQLHLAAYRALGLHDWTYERIECDADQLPGVVG
CCCCCCCCCCCCCCHHHCCCCCCCCCCCCEEHHHHHHHCCCCCCHHHHCCCHHHCCCCCC
GFGPEWVGVSVTMPGKFAALRFADERTEQARRVGSANTLVRTATGWRADNTDIDGVAGAL
CCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCHHHHHH
GAASGWALVCGSGGTAPAAVAGLAQLGVAGITVVARNPDKAARLVRLGDELGVPTRFCAL
HCCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEC
DGAGLADEVAAAEVLVSTLPAEVAERYAGTLARVGVLLDAVYDPWPTPLAAAVSAAGGRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHH
ISGMQMLLHQAFAQVEQFTGLPAPREAMTCAAADAD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHEECCCCCC
>Mature Secondary Structure 
SSTAPPASAGPRRAAVLGKPIGHSKSPQLHLAAYRALGLHDWTYERIECDADQLPGVVG
CCCCCCCCCCCCCHHHCCCCCCCCCCCCEEHHHHHHHCCCCCCHHHHCCCHHHCCCCCC
GFGPEWVGVSVTMPGKFAALRFADERTEQARRVGSANTLVRTATGWRADNTDIDGVAGAL
CCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCHHHHHH
GAASGWALVCGSGGTAPAAVAGLAQLGVAGITVVARNPDKAARLVRLGDELGVPTRFCAL
HCCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEC
DGAGLADEVAAAEVLVSTLPAEVAERYAGTLARVGVLLDAVYDPWPTPLAAAVSAAGGRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHH
ISGMQMLLHQAFAQVEQFTGLPAPREAMTCAAADAD
HHHHHHHHHHHHHHHHHHCCCCCCHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA