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The map label for this gene is dapA_1

Identifier: 41407157

GI number: 41407157

Start: 1110246

End: 1111121

Strand: Direct

Name: dapA_1

Synonym: MAP1059

Alternate gene names: 41407157

Gene position: 1110246-1111121 (Clockwise)

Preceding gene: 41407156

Following gene: 41407161

Centisome position: 22.99

GC content: 68.15

Gene sequence:

>876_bases
TTGACCGAACCCAAGATCCACGGCATCATCGCCTATCCGGTTACGCCCTTCGCCGACAACGGGATTGACACCGAGCGGCT
GGCCGCGCTGGTCGAGCGGGTGGTGTCCGCCGGCGTGCACGCGATCGCGCCGCTGGGCAGCACCGGCGAGCTCGCCTACC
TGGAGGAGCCCGAAGTCGACGCCGTGATCGACACCACCCTGAGCGCCGTCGCCGGCCGGGTGCCGGTGATCGTGGGGGTG
TCGGATGTGACCACCGCCAAGACGATTCGGCGCGCCCAATACGCGCAGCGGGCCGGGGCGGACGCGGTGATGATCCTGCC
GGTGTCCTACTGGAAGCTCACCGAGCGGGAGATCTTCCGTCACTACCGCAGCATCAGCGACGCCATCTCGATTCCGATCA
TGGCCTACAACAACCCGGCCACCAGCGGCGTGGACATGCCGCCGGAGCTGCTGGTGCGGATGTTCGAATCCATCGACAAC
GTGGCCATGGTCAAGGAGTCCACCGGCGACCTGACCCGGATGCAGCGCATCGCCGAGCTGTCCGGCAACCGGCTGCCCTT
CTACAACGGCAGCAACCCGCTGGTGCTCGACGCGCTGAAGGCCGGGGCGTCCGGATGGTGCACGGCCGCACCGTGTTTGC
GGCCGCAACCATGCATCGACCTGTACGGCGCGGTGCGCGCGAACGACCTCGACGCCGCGCAGCGACTCTACGACGACCTC
AAGCCGCTGCTCACCTTCATCGTGGCCGGCGGGCTGGCCACCACCGTCAAGGCCGGCCTGGAGTTGCTCGATTTCAAAGT
CGGCGACCCGCGCGCGCCGTTGCTGCCGCTCGACGAGCAGGGCCGCGCCGAGTTGCGCAAACTGCTTGCGGCCTAA

Upstream 100 bases:

>100_bases
GGACGCTGTCACCGCAGCGCAGCCGGGCCAACTTCGCCTACTACGCCCGCCGGGCCCTGGCCCGCCATCCCGACGCGCTG
ACCAGCTGAGGAGCCAACCC

Downstream 100 bases:

>100_bases
CCTAAGTCGGGCGCGGAGAAGGTGTCGCACTGCTTCGGGTCGCCGGTCTGGTACCCGATGGTGAACCACTTCTGGCGCTG
CTCGGAGGAACCGTGCGTCC

Product: DapA_1

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTEPKIHGIIAYPVTPFADNGIDTERLAALVERVVSAGVHAIAPLGSTGELAYLEEPEVDAVIDTTLSAVAGRVPVIVGV
SDVTTAKTIRRAQYAQRAGADAVMILPVSYWKLTEREIFRHYRSISDAISIPIMAYNNPATSGVDMPPELLVRMFESIDN
VAMVKESTGDLTRMQRIAELSGNRLPFYNGSNPLVLDALKAGASGWCTAAPCLRPQPCIDLYGAVRANDLDAAQRLYDDL
KPLLTFIVAGGLATTVKAGLELLDFKVGDPRAPLLPLDEQGRAELRKLLAA

Sequences:

>Translated_291_residues
MTEPKIHGIIAYPVTPFADNGIDTERLAALVERVVSAGVHAIAPLGSTGELAYLEEPEVDAVIDTTLSAVAGRVPVIVGV
SDVTTAKTIRRAQYAQRAGADAVMILPVSYWKLTEREIFRHYRSISDAISIPIMAYNNPATSGVDMPPELLVRMFESIDN
VAMVKESTGDLTRMQRIAELSGNRLPFYNGSNPLVLDALKAGASGWCTAAPCLRPQPCIDLYGAVRANDLDAAQRLYDDL
KPLLTFIVAGGLATTVKAGLELLDFKVGDPRAPLLPLDEQGRAELRKLLAA
>Mature_290_residues
TEPKIHGIIAYPVTPFADNGIDTERLAALVERVVSAGVHAIAPLGSTGELAYLEEPEVDAVIDTTLSAVAGRVPVIVGVS
DVTTAKTIRRAQYAQRAGADAVMILPVSYWKLTEREIFRHYRSISDAISIPIMAYNNPATSGVDMPPELLVRMFESIDNV
AMVKESTGDLTRMQRIAELSGNRLPFYNGSNPLVLDALKAGASGWCTAAPCLRPQPCIDLYGAVRANDLDAAQRLYDDLK
PLLTFIVAGGLATTVKAGLELLDFKVGDPRAPLLPLDEQGRAELRKLLAA

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=287, Percent_Identity=25.4355400696864, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1786463, Length=237, Percent_Identity=29.535864978903, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI87082415, Length=293, Percent_Identity=25.5972696245734, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1788823, Length=284, Percent_Identity=26.7605633802817, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789620, Length=288, Percent_Identity=28.125, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31309; Mature: 31178

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPKIHGIIAYPVTPFADNGIDTERLAALVERVVSAGVHAIAPLGSTGELAYLEEPEVD
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEECCCCCH
AVIDTTLSAVAGRVPVIVGVSDVTTAKTIRRAQYAQRAGADAVMILPVSYWKLTEREIFR
HHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHH
HYRSISDAISIPIMAYNNPATSGVDMPPELLVRMFESIDNVAMVKESTGDLTRMQRIAEL
HHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHH
SGNRLPFYNGSNPLVLDALKAGASGWCTAAPCLRPQPCIDLYGAVRANDLDAAQRLYDDL
CCCCCCEECCCCCEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
KPLLTFIVAGGLATTVKAGLELLDFKVGDPRAPLLPLDEQGRAELRKLLAA
HHHHHHHHHCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TEPKIHGIIAYPVTPFADNGIDTERLAALVERVVSAGVHAIAPLGSTGELAYLEEPEVD
CCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCCCEEEECCCCCH
AVIDTTLSAVAGRVPVIVGVSDVTTAKTIRRAQYAQRAGADAVMILPVSYWKLTEREIFR
HHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHH
HYRSISDAISIPIMAYNNPATSGVDMPPELLVRMFESIDNVAMVKESTGDLTRMQRIAEL
HHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHH
SGNRLPFYNGSNPLVLDALKAGASGWCTAAPCLRPQPCIDLYGAVRANDLDAAQRLYDDL
CCCCCCEECCCCCEEEHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHH
KPLLTFIVAGGLATTVKAGLELLDFKVGDPRAPLLPLDEQGRAELRKLLAA
HHHHHHHHHCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA