BacMap

Definition	Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession	NC_002944
Length	4,829,781

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The map label for this gene is yngI [H]

Identifier: 41406778

GI number: 41406778

Start: 700495

End: 701898

Strand: Direct

Name: yngI [H]

Synonym: MAP0680

Alternate gene names: 41406778

Gene position: 700495-701898 (Clockwise)

Preceding gene: 41406774

Following gene: 41406779

Centisome position: 14.5

GC content: 71.01

Gene sequence:

>1404_bases
GTGACCGAGCCGGCAGCGCTCGTGTTCGAGGAACGGCGATTCAGCGTGCCCGAACTCGACGCATTGGCCGACGGCTGGGC
CGCCGCGCTGGCCAAGGACGGTGTCACGGCCGGTCGACGGGTCGCAGTGATGACCTCCAACCGGCCCGAATTCCTGGCCG
TGCTGCTCGCCATCTGGCGGTTGGCCGCCACGGCCGTGCTCATCAGCCCGGCGTGGAAGCGCGACGAGGTCGAGCATGCG
CTCGCGTTGACCGATCCCGGGCACGCCGTCGGGGACCATCCGGTGCTGGCCGGCCTGATGCCGATGCTGCACCTGGACGA
GCCGGTCCCGCCCGCGCAGCCGACGGCCGGTGCGCCGCCGCGCGCCGGCGACGCGGTGCTGGTGTTCAGCTCCGGCACCA
CCGGCCTGCCGAAGGCCGTCCGGCACACCCACGCCTCGCTCGACGAGGCGGTGCGGCACTGGCGCGAGGCGCTGCGGCTG
ACACGCCGCGACCGAATCCAGGTGGCGACGCCGCCGTCGCACATCCTGGGCCTGCTGAATCTGCTGACCGCGCTCAAGAC
CGGCGCCTGCGTGCGGCTGCACCCCCGCTTCGACATCGACAAGGTGTTGCACCACATCGAAAGTGACCGCGTCACAGTCG
AAATGGCGGTGGCGCCGATCGCACTGGCCATCGCCTCCCATCCGGATCTCGAGTCCTATGACCTGTCCTCGCTGCGCTAC
ATCGTGTGGGGGGCAACGCCCGTCAACGCTGAGGTCGCCCAGACGGTGACCCGGCGCACCGGGGTGGGTTGGCTGCCCGC
CTACGGGACCACGGAATTGCCGGTGATCGCGTGTAATCCGATCGAGGACGCGCGGCTGGACACCGTCGGACGGCCGGTGC
CCGGCGTCGAGGTGCGGGTCGTCTCGCTCGCGAGCGGCGAGCCGGCCGGAGCGGGCGAGGTCGGTGAGATACAGGCCCGG
TCGGCGTCGCTGATGGCCGGCTATCTGCCGGGCGAGGCGACGGGCGAGGCGATCCGCGACGGGTGGTACCGGACCGGAGA
CGCCGGCTGGCTGGACACCGGCGGGTGGCTGCGCATCACCGACCGTCTCAAGGAGATGATCAAGGTGCGCGGCTTCCAGG
TGGCGCCGGCCGAGATCGAGGCGGTGCTGCAGGGGCATCCCGCCGTCGCGGACTGCGCGGTGTTCGGCGTGCCCGACGGG
CTCAACGGCGAAGCCGTCGTCGCCGCGGTCGCGGTGTCCGCACCGGTGGACGTGACCGAGTTGACCGCCCTGGTGCGCCA
AAAGCTGGCGTCCTACAAACATCTGAGCCGAGTGGTGGTCGTGCCCGAAATCCCCCGCCTGCCTTCGGGCAAGGTGCTGC
GCCGAGTGCTGAAGGAGCGCCATGGATGTACGTCTGACAGCTGA

Upstream 100 bases:

>100_bases
CATTCTTCAGTATAGAGAATACTATTCTCACGGAGCGATAGCATCTTCTCAAGACTGTATGGATGTCGGGTCTGCCCGGC
CTGTCAGGGAAGGACGGGAC

Downstream 100 bases:

>100_bases
ACAACAGCAATTGCGTGATGCCGCCGCCAAGCTGGCCGACGACCTCGGCCCGGCAACGGTGCAGGATCTCGACGACCAGG
GCCGAATCAGCCGGCTGGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTEPAALVFEERRFSVPELDALADGWAAALAKDGVTAGRRVAVMTSNRPEFLAVLLAIWRLAATAVLISPAWKRDEVEHA
LALTDPGHAVGDHPVLAGLMPMLHLDEPVPPAQPTAGAPPRAGDAVLVFSSGTTGLPKAVRHTHASLDEAVRHWREALRL
TRRDRIQVATPPSHILGLLNLLTALKTGACVRLHPRFDIDKVLHHIESDRVTVEMAVAPIALAIASHPDLESYDLSSLRY
IVWGATPVNAEVAQTVTRRTGVGWLPAYGTTELPVIACNPIEDARLDTVGRPVPGVEVRVVSLASGEPAGAGEVGEIQAR
SASLMAGYLPGEATGEAIRDGWYRTGDAGWLDTGGWLRITDRLKEMIKVRGFQVAPAEIEAVLQGHPAVADCAVFGVPDG
LNGEAVVAAVAVSAPVDVTELTALVRQKLASYKHLSRVVVVPEIPRLPSGKVLRRVLKERHGCTSDS

Sequences:

>Translated_467_residues
MTEPAALVFEERRFSVPELDALADGWAAALAKDGVTAGRRVAVMTSNRPEFLAVLLAIWRLAATAVLISPAWKRDEVEHA
LALTDPGHAVGDHPVLAGLMPMLHLDEPVPPAQPTAGAPPRAGDAVLVFSSGTTGLPKAVRHTHASLDEAVRHWREALRL
TRRDRIQVATPPSHILGLLNLLTALKTGACVRLHPRFDIDKVLHHIESDRVTVEMAVAPIALAIASHPDLESYDLSSLRY
IVWGATPVNAEVAQTVTRRTGVGWLPAYGTTELPVIACNPIEDARLDTVGRPVPGVEVRVVSLASGEPAGAGEVGEIQAR
SASLMAGYLPGEATGEAIRDGWYRTGDAGWLDTGGWLRITDRLKEMIKVRGFQVAPAEIEAVLQGHPAVADCAVFGVPDG
LNGEAVVAAVAVSAPVDVTELTALVRQKLASYKHLSRVVVVPEIPRLPSGKVLRRVLKERHGCTSDS
>Mature_466_residues
TEPAALVFEERRFSVPELDALADGWAAALAKDGVTAGRRVAVMTSNRPEFLAVLLAIWRLAATAVLISPAWKRDEVEHAL
ALTDPGHAVGDHPVLAGLMPMLHLDEPVPPAQPTAGAPPRAGDAVLVFSSGTTGLPKAVRHTHASLDEAVRHWREALRLT
RRDRIQVATPPSHILGLLNLLTALKTGACVRLHPRFDIDKVLHHIESDRVTVEMAVAPIALAIASHPDLESYDLSSLRYI
VWGATPVNAEVAQTVTRRTGVGWLPAYGTTELPVIACNPIEDARLDTVGRPVPGVEVRVVSLASGEPAGAGEVGEIQARS
ASLMAGYLPGEATGEAIRDGWYRTGDAGWLDTGGWLRITDRLKEMIKVRGFQVAPAEIEAVLQGHPAVADCAVFGVPDGL
NGEAVVAAVAVSAPVDVTELTALVRQKLASYKHLSRVVVVPEIPRLPSGKVLRRVLKERHGCTSDS

Specific function: Unknown

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI42544132, Length=362, Percent_Identity=27.6243093922652, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI156151445, Length=521, Percent_Identity=26.679462571977, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI38505220, Length=352, Percent_Identity=28.6931818181818, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI122937307, Length=355, Percent_Identity=27.887323943662, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI187761345, Length=476, Percent_Identity=27.7310924369748, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI187761343, Length=476, Percent_Identity=27.7310924369748, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI157311624, Length=355, Percent_Identity=27.0422535211268, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI157311622, Length=355, Percent_Identity=27.0422535211268, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI115511026, Length=353, Percent_Identity=28.0453257790368, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI58082049, Length=355, Percent_Identity=26.4788732394366, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI28416953, Length=549, Percent_Identity=25.6830601092896, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI8923896, Length=124, Percent_Identity=33.8709677419355, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI253970489, Length=124, Percent_Identity=33.8709677419355, Blast_Score=73, Evalue=7e-13,
Organism=Homo sapiens, GI13375727, Length=123, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI42544134, Length=191, Percent_Identity=26.1780104712042, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI40807491, Length=207, Percent_Identity=30.4347826086957, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI145693145, Length=486, Percent_Identity=28.3950617283951, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1788107, Length=345, Percent_Identity=34.2028985507246, Blast_Score=158, Evalue=9e-40,
Organism=Escherichia coli, GI1786810, Length=494, Percent_Identity=26.1133603238866, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI221142682, Length=493, Percent_Identity=25.3549695740365, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1789201, Length=351, Percent_Identity=31.0541310541311, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788595, Length=463, Percent_Identity=25.9179265658747, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790505, Length=360, Percent_Identity=25.2777777777778, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786529, Length=277, Percent_Identity=28.158844765343, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17557194, Length=489, Percent_Identity=28.4253578732106, Blast_Score=175, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17538037, Length=487, Percent_Identity=28.952772073922, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI17559526, Length=356, Percent_Identity=33.7078651685393, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI25141359, Length=475, Percent_Identity=29.2631578947368, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17531443, Length=359, Percent_Identity=32.5905292479109, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI32563687, Length=485, Percent_Identity=27.4226804123711, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17558820, Length=481, Percent_Identity=27.8586278586279, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71985884, Length=364, Percent_Identity=28.2967032967033, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17560140, Length=390, Percent_Identity=28.2051282051282, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71996755, Length=350, Percent_Identity=28.8571428571429, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17560308, Length=355, Percent_Identity=28.169014084507, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71994703, Length=353, Percent_Identity=28.328611898017, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71994694, Length=351, Percent_Identity=28.4900284900285, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71994690, Length=351, Percent_Identity=28.4900284900285, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25141361, Length=257, Percent_Identity=25.6809338521401, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17564090, Length=326, Percent_Identity=26.9938650306748, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319699, Length=359, Percent_Identity=27.8551532033426, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6319264, Length=379, Percent_Identity=25.3298153034301, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6323182, Length=401, Percent_Identity=24.9376558603491, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6320852, Length=396, Percent_Identity=23.7373737373737, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355181, Length=479, Percent_Identity=32.3590814196242, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI18859661, Length=501, Percent_Identity=29.1417165668663, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24648253, Length=475, Percent_Identity=27.7894736842105, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21356441, Length=342, Percent_Identity=31.2865497076023, Blast_Score=136, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24648255, Length=365, Percent_Identity=31.2328767123288, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI281365686, Length=356, Percent_Identity=27.8089887640449, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24648260, Length=473, Percent_Identity=25.369978858351, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24648257, Length=373, Percent_Identity=30.5630026809651, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21358303, Length=319, Percent_Identity=28.5266457680251, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI19922652, Length=472, Percent_Identity=26.4830508474576, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24581924, Length=511, Percent_Identity=26.027397260274, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI21356947, Length=357, Percent_Identity=28.2913165266106, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24653035, Length=348, Percent_Identity=27.5862068965517, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI161076582, Length=355, Percent_Identity=27.3239436619718, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI20130357, Length=352, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28573631, Length=531, Percent_Identity=23.728813559322, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI20130353, Length=531, Percent_Identity=23.728813559322, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24656500, Length=354, Percent_Identity=26.5536723163842, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648676, Length=471, Percent_Identity=24.8407643312102, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667959, Length=360, Percent_Identity=25.2777777777778, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI62472339, Length=360, Percent_Identity=25.2777777777778, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24667955, Length=360, Percent_Identity=25.2777777777778, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355225, Length=185, Percent_Identity=28.1081081081081, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: NA

Molecular weight: Translated: 49829; Mature: 49698

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPAALVFEERRFSVPELDALADGWAAALAKDGVTAGRRVAVMTSNRPEFLAVLLAIWR
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHH
LAATAVLISPAWKRDEVEHALALTDPGHAVGDHPVLAGLMPMLHLDEPVPPAQPTAGAPP
HHHHHHHCCCCCCCHHHHHEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
RAGDAVLVFSSGTTGLPKAVRHTHASLDEAVRHWREALRLTRRDRIQVATPPSHILGLLN
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHH
LLTALKTGACVRLHPRFDIDKVLHHIESDRVTVEMAVAPIALAIASHPDLESYDLSSLRY
HHHHHCCCCEEEECCCCCHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCEEE
IVWGATPVNAEVAQTVTRRTGVGWLPAYGTTELPVIACNPIEDARLDTVGRPVPGVEVRV
EEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCHHHCCCCCCCCEEEE
VSLASGEPAGAGEVGEIQARSASLMAGYLPGEATGEAIRDGWYRTGDAGWLDTGGWLRIT
EEEECCCCCCCCCCCHHHHCCHHHEEECCCCCCCCHHHHCCCEECCCCCEECCCCEEEEH
DRLKEMIKVRGFQVAPAEIEAVLQGHPAVADCAVFGVPDGLNGEAVVAAVAVSAPVDVTE
HHHHHHHHHCCCEECHHHHHHHHCCCCCHHHEEEEECCCCCCCCEEEEEEEECCCCCHHH
LTALVRQKLASYKHLSRVVVVPEIPRLPSGKVLRRVLKERHGCTSDS
HHHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TEPAALVFEERRFSVPELDALADGWAAALAKDGVTAGRRVAVMTSNRPEFLAVLLAIWR
CCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHH
LAATAVLISPAWKRDEVEHALALTDPGHAVGDHPVLAGLMPMLHLDEPVPPAQPTAGAPP
HHHHHHHCCCCCCCHHHHHEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
RAGDAVLVFSSGTTGLPKAVRHTHASLDEAVRHWREALRLTRRDRIQVATPPSHILGLLN
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHH
LLTALKTGACVRLHPRFDIDKVLHHIESDRVTVEMAVAPIALAIASHPDLESYDLSSLRY
HHHHHCCCCEEEECCCCCHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCEEE
IVWGATPVNAEVAQTVTRRTGVGWLPAYGTTELPVIACNPIEDARLDTVGRPVPGVEVRV
EEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCHHHCCCCCCCCEEEE
VSLASGEPAGAGEVGEIQARSASLMAGYLPGEATGEAIRDGWYRTGDAGWLDTGGWLRIT
EEEECCCCCCCCCCCHHHHCCHHHEEECCCCCCCCHHHHCCCEECCCCCEECCCCEEEEH
DRLKEMIKVRGFQVAPAEIEAVLQGHPAVADCAVFGVPDGLNGEAVVAAVAVSAPVDVTE
HHHHHHHHHCCCEECHHHHHHHHCCCCCHHHEEEEECCCCCCCCEEEEEEEECCCCCHHH
LTALVRQKLASYKHLSRVVVVPEIPRLPSGKVLRRVLKERHGCTSDS
HHHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]