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The map label for this gene is lpqR

Identifier: 41406768

GI number: 41406768

Start: 691802

End: 692539

Strand: Direct

Name: lpqR

Synonym: MAP0670

Alternate gene names: 41406768

Gene position: 691802-692539 (Clockwise)

Preceding gene: 41406767

Following gene: 41406769

Centisome position: 14.32

GC content: 67.62

Gene sequence:

>738_bases
CTGACCCCGGCGCGGCCGACCAACCGGGATAATGACCGCATGCGTCTCGCGTGGGTGCTGCGACTGACGATTGCGGCGTC
GTTGGTCGCGGCGGGCGGGACGCGTACCGCCGAGGCCAGCCCGGATGTCCCGCCGGTCAGCGACGCCGCGAAAGCGGCCG
GCTTCGTGGACATCCGCAGCGTCATTCCCGATGCGGTGCTCGACCTGCGCTATGCGACGTCCAACAATTTCACCCATACG
CAGCTGTATCCCTCCGACGCCAGATGCCTTGTGCACCAATCGATGGCTCCCGGCCTTGCCGCGGCCGCCGGTGCGCTGCG
CCCACAGGGTCACCTGCTGGTGTTCTGGGACTGCTATCGCCCGCATGACGTCCAGGTAAAGATGTTCAGCCTGGTCCCCA
ACCCCGCCTGGGTGGCCCGCCCGGGCGCGTATGCCCGCAGCCACGAGTCGGGGCGTTCGGTGGACGTGACCTTCACGACG
GCACAGCAGCCTTGCTCGTCCGGGTTGCACGCCGGCGGGCTGTGTCTGGCCGACATGGGCACTGACTTCGACGACTTCAC
CTCGAGGGCAACGGCTTTCAACACGCAGGGCATCAGTGCCGACGCGGTGGCGAACCGGGCCGCGCTGCGCAACGCCATGA
ATTACGGCGGATTGAAGGTGTACTCGGGGGAGTGGTGGCATTTCGACGGCCCGGGGGCCGGTGTGGACCAACCGATCCTC
AACGTCCCCGTCGACTAG

Upstream 100 bases:

>100_bases
AACGTCACAAACGTCACGGTGGGGCTGGTGCGATTGACTTCGCACCAGCCTCACTGGTTTTTCCGATCGCTGAACGGCCG
GTGGCGACAACACCCGGCGG

Downstream 100 bases:

>100_bases
GTGTCTCATATTCCGAGACGAGAGTTTCATTATATGGGGCACCGTCGGTAGCCTGGCCGAACAAGGACACGCGCGAGCCG
AGGGGCCACAGTGAACGACC

Product: LpqR

Products: NA

Alternate protein names: D-Ala-D-Ala dipeptidase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTPARPTNRDNDRMRLAWVLRLTIAASLVAAGGTRTAEASPDVPPVSDAAKAAGFVDIRSVIPDAVLDLRYATSNNFTHT
QLYPSDARCLVHQSMAPGLAAAAGALRPQGHLLVFWDCYRPHDVQVKMFSLVPNPAWVARPGAYARSHESGRSVDVTFTT
AQQPCSSGLHAGGLCLADMGTDFDDFTSRATAFNTQGISADAVANRAALRNAMNYGGLKVYSGEWWHFDGPGAGVDQPIL
NVPVD

Sequences:

>Translated_245_residues
MTPARPTNRDNDRMRLAWVLRLTIAASLVAAGGTRTAEASPDVPPVSDAAKAAGFVDIRSVIPDAVLDLRYATSNNFTHT
QLYPSDARCLVHQSMAPGLAAAAGALRPQGHLLVFWDCYRPHDVQVKMFSLVPNPAWVARPGAYARSHESGRSVDVTFTT
AQQPCSSGLHAGGLCLADMGTDFDDFTSRATAFNTQGISADAVANRAALRNAMNYGGLKVYSGEWWHFDGPGAGVDQPIL
NVPVD
>Mature_244_residues
TPARPTNRDNDRMRLAWVLRLTIAASLVAAGGTRTAEASPDVPPVSDAAKAAGFVDIRSVIPDAVLDLRYATSNNFTHTQ
LYPSDARCLVHQSMAPGLAAAAGALRPQGHLLVFWDCYRPHDVQVKMFSLVPNPAWVARPGAYARSHESGRSVDVTFTTA
QQPCSSGLHAGGLCLADMGTDFDDFTSRATAFNTQGISADAVANRAALRNAMNYGGLKVYSGEWWHFDGPGAGVDQPILN
VPVD

Specific function: Hydrolyzes D-Ala-D-Ala. May have a role in cell-wall turnover [H]

COG id: COG2173

COG function: function code M; D-alanyl-D-alanine dipeptidase

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15D family [H]

Homologues:

Organism=Escherichia coli, GI1787763, Length=179, Percent_Identity=31.2849162011173, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009045
- InterPro:   IPR000755 [H]

Pfam domain/function: PF01427 Peptidase_M15 [H]

EC number: =3.4.13.22 [H]

Molecular weight: Translated: 26166; Mature: 26034

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPARPTNRDNDRMRLAWVLRLTIAASLVAAGGTRTAEASPDVPPVSDAAKAAGFVDIRS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCHHHHHH
VIPDAVLDLRYATSNNFTHTQLYPSDARCLVHQSMAPGLAAAAGALRPQGHLLVFWDCYR
HCCHHHHEEEEECCCCEEEEEECCCCCCEEEHHHCCCCHHHHHHCCCCCCCEEEEEECCC
PHDVQVKMFSLVPNPAWVARPGAYARSHESGRSVDVTFTTAQQPCSSGLHAGGLCLADMG
CCCCEEEEEEECCCCCEEECCCCHHCCCCCCCEEEEEEECCCCHHHCCCCCCCEEEECCC
TDFDDFTSRATAFNTQGISADAVANRAALRNAMNYGGLKVYSGEWWHFDGPGAGVDQPIL
CCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCCCCCE
NVPVD
ECCCC
>Mature Secondary Structure 
TPARPTNRDNDRMRLAWVLRLTIAASLVAAGGTRTAEASPDVPPVSDAAKAAGFVDIRS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCHHHHHH
VIPDAVLDLRYATSNNFTHTQLYPSDARCLVHQSMAPGLAAAAGALRPQGHLLVFWDCYR
HCCHHHHEEEEECCCCEEEEEECCCCCCEEEHHHCCCCHHHHHHCCCCCCCEEEEEECCC
PHDVQVKMFSLVPNPAWVARPGAYARSHESGRSVDVTFTTAQQPCSSGLHAGGLCLADMG
CCCCEEEEEEECCCCCEEECCCCHHCCCCCCCEEEEEEECCCCHHHCCCCCCCEEEECCC
TDFDDFTSRATAFNTQGISADAVANRAALRNAMNYGGLKVYSGEWWHFDGPGAGVDQPIL
CCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCCCCCE
NVPVD
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]