Click here to switch to the map view.

The map label for this gene is panC

Identifier: 41406554

GI number: 41406554

Start: 483757

End: 484683

Strand: Direct

Name: panC

Synonym: MAP0456

Alternate gene names: 41406554

Gene position: 483757-484683 (Clockwise)

Preceding gene: 41406553

Following gene: 41406555

Centisome position: 10.02

GC content: 71.2

Gene sequence:

>927_bases
GTGAAACCCGCCTTCACCGCGGGCGAACTCAACACCTACACCAGCCCGGGCGACGTCACCGCCGTCAGCCGCGCGCTGCG
CCACACCGGCCGCCGGGTGATGCTGGTGCCCACCATGGGTGCGCTGCACGACGGCCACCTCGCGCTGGTGCGGGCGGCCA
AGCGGGTGCCCGGTTCGGTGGTGGTGGTGTCGATCTTCGTCAACCCGCTGCAATTCGGCGCCGGCGAAGACCTGGACGCC
TACCCCCGCACCCTGGACGACGACCTGGCGCTGCTGCGCTCCGAGGGCGTCGAAATCGCCTTCACCCCAACGGCCGCGGC
GATGTACCCGAATGGTTTGCGCACCACCGTGCAGCCCGGCCCGCTGGCCGCCGAGCTGGAGGGCGGGCCCCGGCCGACGC
ATTTCGCCGGCGTGCTGACCGTCGTGTGCAAGCTGCTGCAGATCGTGCGCCCGGACCGAATCTTCTTCGGCGAGAAGGAC
TACCAGCAGCTGGTGATGATCCGTCAGATGGTCGCCGACCTCAACATCGACGTGCAGGTGGTCGGGGTGCCGACCGTGCG
GGAGGCCGACGGCCTGGCGATGTCGTCGCGCAACCGCTACCTGGACGCCACGCAACGCGAACTGGCCGTGACGCTTTCGG
CGGCCCTGACCGCCGGCGCGCACGCCGCTCACCTGGGCGGTGCGGCCGCGCTGCGGGCCGCGCGGGCGGTGCTGGACGCC
GTGCCCGAGCTCACCGTCGACTATCTCGAGCTGCGCGACGCCGGGCTGGGCCCGGCACCCGCCCACGGCTCGGCGCGGCT
GCTGGTCGCCGCCCGGCTGGGCAACACCCGACTGCTGGATAACATCGAAATGCAGATCGAAACACCCGCCGGCACCGCTG
GGCCGGACGGCGACCGCCAATACGCCCAATCACCTTGGAGGAATTGA

Upstream 100 bases:

>100_bases
ACCGGGTGGCACCCGAGCTGGCACAGGCCTATCGGGTCAACGCCCTGCGCACCGCCCAGCGGGCGCACGCTCCCCAGGAG
GTCGTCGAGGTGCTGGCACC

Downstream 100 bases:

>100_bases
TGTTACGGACGATGCTCAAGTCGAAGATCCACCGGGCCACCGTCACGCAGGCCGACCTGCACTACGTGGGCTCGGTGACC
ATCGACGCCGACCTGATGGA

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKPAFTAGELNTYTSPGDVTAVSRALRHTGRRVMLVPTMGALHDGHLALVRAAKRVPGSVVVVSIFVNPLQFGAGEDLDA
YPRTLDDDLALLRSEGVEIAFTPTAAAMYPNGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVCKLLQIVRPDRIFFGEKD
YQQLVMIRQMVADLNIDVQVVGVPTVREADGLAMSSRNRYLDATQRELAVTLSAALTAGAHAAHLGGAAALRAARAVLDA
VPELTVDYLELRDAGLGPAPAHGSARLLVAARLGNTRLLDNIEMQIETPAGTAGPDGDRQYAQSPWRN

Sequences:

>Translated_308_residues
MKPAFTAGELNTYTSPGDVTAVSRALRHTGRRVMLVPTMGALHDGHLALVRAAKRVPGSVVVVSIFVNPLQFGAGEDLDA
YPRTLDDDLALLRSEGVEIAFTPTAAAMYPNGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVCKLLQIVRPDRIFFGEKD
YQQLVMIRQMVADLNIDVQVVGVPTVREADGLAMSSRNRYLDATQRELAVTLSAALTAGAHAAHLGGAAALRAARAVLDA
VPELTVDYLELRDAGLGPAPAHGSARLLVAARLGNTRLLDNIEMQIETPAGTAGPDGDRQYAQSPWRN
>Mature_308_residues
MKPAFTAGELNTYTSPGDVTAVSRALRHTGRRVMLVPTMGALHDGHLALVRAAKRVPGSVVVVSIFVNPLQFGAGEDLDA
YPRTLDDDLALLRSEGVEIAFTPTAAAMYPNGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVCKLLQIVRPDRIFFGEKD
YQQLVMIRQMVADLNIDVQVVGVPTVREADGLAMSSRNRYLDATQRELAVTLSAALTAGAHAAHLGGAAALRAARAVLDA
VPELTVDYLELRDAGLGPAPAHGSARLLVAARLGNTRLLDNIEMQIETPAGTAGPDGDRQYAQSPWRN

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=273, Percent_Identity=47.2527472527472, Blast_Score=214, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6322046, Length=244, Percent_Identity=38.9344262295082, Blast_Score=167, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 32737; Mature: 32737

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPAFTAGELNTYTSPGDVTAVSRALRHTGRRVMLVPTMGALHDGHLALVRAAKRVPGSV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCE
VVVSIFVNPLQFGAGEDLDAYPRTLDDDLALLRSEGVEIAFTPTAAAMYPNGLRTTVQPG
EEEEEEECHHHCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCHHHHCCCCCEECCCCC
PLAAELEGGPRPTHFAGVLTVVCKLLQIVRPDRIFFGEKDYQQLVMIRQMVADLNIDVQV
CEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCCCCEEE
VGVPTVREADGLAMSSRNRYLDATQRELAVTLSAALTAGAHAAHLGGAAALRAARAVLDA
EECCCEECCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHH
VPELTVDYLELRDAGLGPAPAHGSARLLVAARLGNTRLLDNIEMQIETPAGTAGPDGDRQ
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCEEEECEEEEEECCCCCCCCCCCHH
YAQSPWRN
HHCCCCCC
>Mature Secondary Structure
MKPAFTAGELNTYTSPGDVTAVSRALRHTGRRVMLVPTMGALHDGHLALVRAAKRVPGSV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCE
VVVSIFVNPLQFGAGEDLDAYPRTLDDDLALLRSEGVEIAFTPTAAAMYPNGLRTTVQPG
EEEEEEECHHHCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCHHHHCCCCCEECCCCC
PLAAELEGGPRPTHFAGVLTVVCKLLQIVRPDRIFFGEKDYQQLVMIRQMVADLNIDVQV
CEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCCCCEEE
VGVPTVREADGLAMSSRNRYLDATQRELAVTLSAALTAGAHAAHLGGAAALRAARAVLDA
EECCCEECCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHH
VPELTVDYLELRDAGLGPAPAHGSARLLVAARLGNTRLLDNIEMQIETPAGTAGPDGDRQ
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCEEEECEEEEEECCCCCCCCCCCHH
YAQSPWRN
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA