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The map label for this gene is folX

Identifier: 41406549

GI number: 41406549

Start: 479723

End: 480124

Strand: Direct

Name: folX

Synonym: MAP0451

Alternate gene names: 41406549

Gene position: 479723-480124 (Clockwise)

Preceding gene: 41406548

Following gene: 41406550

Centisome position: 9.93

GC content: 70.4

Gene sequence:

>402_bases
ATGGCTGATCGAATCGAGTTGCGCGGCTTGAGGGTTCGCGGACAACACGGAGTGTTCGACCACGAGCGCGTCGACGGGCA
GGACTTCGTCATCGACGTCACGGTCTGGATCGACCTGGTGGGCGCCGCGGCCAGCGACGAGCTGGCCGACACCTACGACT
ACGCCGCGCTGGCGCAGTTGGCCGCCGACGTGGTGGCCGGCCCGGCACGCAATCTGATCGAAACCGTCGGGGCGCAGATC
GCCGACCAGGTGATGGACGACGAACGTGTGCACGCCGTCGAGGTGGTGGTGCACAAGCCGCAGGCCCCGATCCCGCAGCA
GTTCGCCGACGTCGCGGTGGTGGTGCGGCGGTCCCGGCGCGGCGGCCGCGGTTCGGTGGTCCCGGCGGGCGGGGCGCTAT
GA

Upstream 100 bases:

>100_bases
TCCGCGCTGGCCGCGCTGCACGGGGCGTGGGGGGTGCGGGTGCACGACGTGCGGGCCACGGTCGATGCGCTCAAGGTGCT
CGGCGCTTGGATGGGAGACG

Downstream 100 bases:

>100_bases
CACGCGACGACGACGATGACGCCGGCGCAGCCGGGGTTGAGGAGCGGCGCCAATGACACGCGACGACGACGATGACGCCG
GCGCAGCCGCGGTTGAGGAG

Product: FolX

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MADRIELRGLRVRGQHGVFDHERVDGQDFVIDVTVWIDLVGAAASDELADTYDYAALAQLAADVVAGPARNLIETVGAQI
ADQVMDDERVHAVEVVVHKPQAPIPQQFADVAVVVRRSRRGGRGSVVPAGGAL

Sequences:

>Translated_133_residues
MADRIELRGLRVRGQHGVFDHERVDGQDFVIDVTVWIDLVGAAASDELADTYDYAALAQLAADVVAGPARNLIETVGAQI
ADQVMDDERVHAVEVVVHKPQAPIPQQFADVAVVVRRSRRGGRGSVVPAGGAL
>Mature_132_residues
ADRIELRGLRVRGQHGVFDHERVDGQDFVIDVTVWIDLVGAAASDELADTYDYAALAQLAADVVAGPARNLIETVGAQIA
DQVMDDERVHAVEVVVHKPQAPIPQQFADVAVVVRRSRRGGRGSVVPAGGAL

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 14232; Mature: 14101

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRIELRGLRVRGQHGVFDHERVDGQDFVIDVTVWIDLVGAAASDELADTYDYAALAQL
CCCCCEECEEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AADVVAGPARNLIETVGAQIADQVMDDERVHAVEVVVHKPQAPIPQQFADVAVVVRRSRR
HHHHHCCCHHHHHHHHHHHHHHHHHCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHHCC
GGRGSVVPAGGAL
CCCCCCCCCCCCC
>Mature Secondary Structure 
ADRIELRGLRVRGQHGVFDHERVDGQDFVIDVTVWIDLVGAAASDELADTYDYAALAQL
CCCCEECEEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AADVVAGPARNLIETVGAQIADQVMDDERVHAVEVVVHKPQAPIPQQFADVAVVVRRSRR
HHHHHCCCHHHHHHHHHHHHHHHHHCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHHCC
GGRGSVVPAGGAL
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]