| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is dacB [H]
Identifier: 41406534
GI number: 41406534
Start: 463606
End: 464991
Strand: Direct
Name: dacB [H]
Synonym: MAP0436
Alternate gene names: 41406534
Gene position: 463606-464991 (Clockwise)
Preceding gene: 41406532
Following gene: 41406535
Centisome position: 9.6
GC content: 73.38
Gene sequence:
>1386_bases ATGGCCCGTACTCGCTGGCAGAAATCCACCCCAGTGTTCATCGGGTTGGGCGTGCTGGCGTTCGTCGCTGCCGTGGTGGT TGCGGCAACGTTTTTCACCACGACCGGGCACGGCGCGGGCAACGCGCACGCCCCGATACCGGCTCCGCATGCGCCCACGG TCAAGCCGGGCATGCTGCCGGTCAGCGACACCGCCGAGCTACCCACCGGACCCGGGGTGAGCGCCGCGCTGGCGCCGGTG GCTGCCGATCCCAACCTGGGCCGGCTGGGCGGCCGGATCACCGACGCCATCACCGGCAAAGAGCTGTGGCAGGTGGCCGA CGACATGCCGTTGGTGCCGGCGTCCACCAACAAGGTGCTGACCGCCGCGGCGGCGCTGCTGACCCTGGACCGGCAGGCCC GGATCAGCACCCGGGTGGTGGCCGGCAGCCAGAACGCGCAGGGGCCCGTCGTGCTGGTGGGTGCGGGCGACCCGGTGCTG TCGGCGGCCCCGCCCGGGCAGCCGACCTGGTATCGGGGCGCGGCCCGGATCAGCGACCTGGTCGAGCAGATCCGCCGCAG CGGGGTGACGCCGACCGCGGTGCAGGTGGACACCTCGGCGTTCAGCGGGCCGACGATGGCGCAGGGCTGGGATCCCTCCG ACGTGGACAACGGCGACATCGCGCCGATCGAGTCGGTGATGATCGACGCCGGACGCATCCAGCCGACCACGGTCAACTCC CGCCGCACCCGCACACCGGCGCTGGACGCGGGCCGGGAGCTGGCCAAGGCGCTGGGGTTGGACCCCAACGCGGTGACGGT CGCGACGGCGCCGTCCGGGGCGCGGCAGCTGGCCGTCGTGCAGTCGGCGCCGCTGGTGCAGCGGCTGTCGGAGATGATGG ACCACTCCGACAACGTGCTGGCCGAGTGCATCGCCCGGGAGGTCGCGGCGGCCATCAACCGGCCGCGCAGCTTCGCGGGT GCGGCCGACGCGGTCACCAACCGGCTCAGCACCGCCCACGTCGACACCGCCGGCGCGACGCTGATGGATTCCAGCGGGCT GTCGGTGGACGACCGGCTGACGGCCAAGACGCTCGACGGCGTGCTGCAGGCCGCCGCCGGGCCGGACCAGCCGGCGCTGC GGGCGCTGCTGGATTTGCTGCCGATCGCCGCCGGCAGCGGCACCCTGGGCGACCGGTTCACCGACGCCTCGACCAACCAG GGCCCGGCCGGCTGGCTGCGCGCCAAGACCGGCTCGCTGACCGCCATCAACGCGCTGGCCGGCGTGCTTACCGACCGCAG CGGGCGGGTGCTGACGTTCGCGTTCATCTCCAACGATGCCGGCCCCAACGGCCGCAACGCGATGGACGCGCTGGCCACCC GGCTCTGGTTCTGCGGGTGCTCATGA
Upstream 100 bases:
>100_bases TAGGCAGTCTGGGAAGGCAGGCCAATTTTGCTCTGCTACACCCTAGTCGAGCCCGGCGGCGCCGATTCGGCAGAATGGCG TGCAGACAGTCAGGAGAGTG
Downstream 100 bases:
>100_bases CGCCGGCGCCCGATCTGACGCTGGGTACCGCCGTCGACTGGCGATTCGCGGCGACCGTCGGCCGGCGGCTGGCCCGGCCC GGCCCGCCGTCCACCGACTA
Product: hypothetical protein
Products: NA
Alternate protein names: DD-carboxypeptidase; DD-peptidase; D-alanyl-D-alanine endopeptidase; DD-endopeptidase; Penicillin-binding protein 4; PBP-4 [H]
Number of amino acids: Translated: 461; Mature: 460
Protein sequence:
>461_residues MARTRWQKSTPVFIGLGVLAFVAAVVVAATFFTTTGHGAGNAHAPIPAPHAPTVKPGMLPVSDTAELPTGPGVSAALAPV AADPNLGRLGGRITDAITGKELWQVADDMPLVPASTNKVLTAAAALLTLDRQARISTRVVAGSQNAQGPVVLVGAGDPVL SAAPPGQPTWYRGAARISDLVEQIRRSGVTPTAVQVDTSAFSGPTMAQGWDPSDVDNGDIAPIESVMIDAGRIQPTTVNS RRTRTPALDAGRELAKALGLDPNAVTVATAPSGARQLAVVQSAPLVQRLSEMMDHSDNVLAECIAREVAAAINRPRSFAG AADAVTNRLSTAHVDTAGATLMDSSGLSVDDRLTAKTLDGVLQAAAGPDQPALRALLDLLPIAAGSGTLGDRFTDASTNQ GPAGWLRAKTGSLTAINALAGVLTDRSGRVLTFAFISNDAGPNGRNAMDALATRLWFCGCS
Sequences:
>Translated_461_residues MARTRWQKSTPVFIGLGVLAFVAAVVVAATFFTTTGHGAGNAHAPIPAPHAPTVKPGMLPVSDTAELPTGPGVSAALAPV AADPNLGRLGGRITDAITGKELWQVADDMPLVPASTNKVLTAAAALLTLDRQARISTRVVAGSQNAQGPVVLVGAGDPVL SAAPPGQPTWYRGAARISDLVEQIRRSGVTPTAVQVDTSAFSGPTMAQGWDPSDVDNGDIAPIESVMIDAGRIQPTTVNS RRTRTPALDAGRELAKALGLDPNAVTVATAPSGARQLAVVQSAPLVQRLSEMMDHSDNVLAECIAREVAAAINRPRSFAG AADAVTNRLSTAHVDTAGATLMDSSGLSVDDRLTAKTLDGVLQAAAGPDQPALRALLDLLPIAAGSGTLGDRFTDASTNQ GPAGWLRAKTGSLTAINALAGVLTDRSGRVLTFAFISNDAGPNGRNAMDALATRLWFCGCS >Mature_460_residues ARTRWQKSTPVFIGLGVLAFVAAVVVAATFFTTTGHGAGNAHAPIPAPHAPTVKPGMLPVSDTAELPTGPGVSAALAPVA ADPNLGRLGGRITDAITGKELWQVADDMPLVPASTNKVLTAAAALLTLDRQARISTRVVAGSQNAQGPVVLVGAGDPVLS AAPPGQPTWYRGAARISDLVEQIRRSGVTPTAVQVDTSAFSGPTMAQGWDPSDVDNGDIAPIESVMIDAGRIQPTTVNSR RTRTPALDAGRELAKALGLDPNAVTVATAPSGARQLAVVQSAPLVQRLSEMMDHSDNVLAECIAREVAAAINRPRSFAGA ADAVTNRLSTAHVDTAGATLMDSSGLSVDDRLTAKTLDGVLQAAAGPDQPALRALLDLLPIAAGSGTLGDRFTDASTNQG PAGWLRAKTGSLTAINALAGVLTDRSGRVLTFAFISNDAGPNGRNAMDALATRLWFCGCS
Specific function: Not involved in transpeptidation but exclusively catalyzes a DD-carboxypeptidase and DD-endopeptidase reaction [H]
COG id: COG2027
COG function: function code M; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
Gene ontology:
Cell location: Periplasm (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S13 family [H]
Homologues:
Organism=Escherichia coli, GI1789573, Length=156, Percent_Identity=35.8974358974359, Blast_Score=69, Evalue=4e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR000667 [H]
Pfam domain/function: PF02113 Peptidase_S13 [H]
EC number: =3.4.16.4 [H]
Molecular weight: Translated: 47149; Mature: 47018
Theoretical pI: Translated: 6.68; Mature: 6.68
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MARTRWQKSTPVFIGLGVLAFVAAVVVAATFFTTTGHGAGNAHAPIPAPHAPTVKPGMLP CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC VSDTAELPTGPGVSAALAPVAADPNLGRLGGRITDAITGKELWQVADDMPLVPASTNKVL CCCCCCCCCCCCCHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHH TAAAALLTLDRQARISTRVVAGSQNAQGPVVLVGAGDPVLSAAPPGQPTWYRGAARISDL HHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH VEQIRRSGVTPTAVQVDTSAFSGPTMAQGWDPSDVDNGDIAPIESVMIDAGRIQPTTVNS HHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCC RRTRTPALDAGRELAKALGLDPNAVTVATAPSGARQLAVVQSAPLVQRLSEMMDHSDNVL CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEHHHCCHHHHHHHHHHCCCHHHH AECIAREVAAAINRPRSFAGAADAVTNRLSTAHVDTAGATLMDSSGLSVDDRLTAKTLDG HHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHH VLQAAAGPDQPALRALLDLLPIAAGSGTLGDRFTDASTNQGPAGWLRAKTGSLTAINALA HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHH GVLTDRSGRVLTFAFISNDAGPNGRNAMDALATRLWFCGCS HHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCC >Mature Secondary Structure ARTRWQKSTPVFIGLGVLAFVAAVVVAATFFTTTGHGAGNAHAPIPAPHAPTVKPGMLP CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC VSDTAELPTGPGVSAALAPVAADPNLGRLGGRITDAITGKELWQVADDMPLVPASTNKVL CCCCCCCCCCCCCHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHH TAAAALLTLDRQARISTRVVAGSQNAQGPVVLVGAGDPVLSAAPPGQPTWYRGAARISDL HHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH VEQIRRSGVTPTAVQVDTSAFSGPTMAQGWDPSDVDNGDIAPIESVMIDAGRIQPTTVNS HHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCC RRTRTPALDAGRELAKALGLDPNAVTVATAPSGARQLAVVQSAPLVQRLSEMMDHSDNVL CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEHHHCCHHHHHHHHHHCCCHHHH AECIAREVAAAINRPRSFAGAADAVTNRLSTAHVDTAGATLMDSSGLSVDDRLTAKTLDG HHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHH VLQAAAGPDQPALRALLDLLPIAAGSGTLGDRFTDASTNQGPAGWLRAKTGSLTAINALA HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHH GVLTDRSGRVLTFAFISNDAGPNGRNAMDALATRLWFCGCS HHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2040429; 9278503; 2046551 [H]