| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is fabG [H]
Identifier: 41406448
GI number: 41406448
Start: 374972
End: 375745
Strand: Direct
Name: fabG [H]
Synonym: MAP0350
Alternate gene names: 41406448
Gene position: 374972-375745 (Clockwise)
Preceding gene: 41406447
Following gene: 41406449
Centisome position: 7.76
GC content: 70.03
Gene sequence:
>774_bases ATGAGCTACAGCCACCCGGATTCGATGCGCGGGCAGGTCGCGATCGTCACCGGCGCCGCGCAGGGCGTCGGCAAGGGCAT CGCCGCCGCGCTGCTGGAACGCGGCGCGGCGGTGCTGTTGGTCGACATTCAACAAGAAACCCTGGAGGCGACGGCCACCG AACTCCGCGCACTGGGGCGGGTGGAACGGCTCGTCACCGATCTGCGCGACCCCGACAGCGCCCCGCGCATCGCGGCGGCC GCCGTCGACGCGTTCGGCTCGGTGCACGGGCTGGTCAACAACGCCATCGCCACCAACGAGCCCAAGGCATTCGTCGACAT CACCACCGACGACCTCGCGCTGGGCTATGAGGTCGGCCCCCGCGCCACCTTCCTGCTCATGCAGGCGGTGCACCCGCTGC TGGTGAAGGAGGGCGGCGGGGCGATCGTCAACCTCGGCTCGGGGACGGGCACCGGCGGCGAGCCCAGATGGGGCGGGTAT GCCGCCGCCAAGGAAGGCATCCGGGGCCTGTCCAAGGTGGCGGCGCTGGAGTGGGGACGCGACAACATCCGCGTCAACGT CGTCTGCCCGTTCGCCGAGTCCGACGGCGTGAAGCTGTGGAAGCAGTTCGCGCCCAACGACTATGCGAAGGCGGTCGGAC GGGTGCCGATGAAGCGGATCGGCGACGTGCGCACCGACGTGGGTGCGCTGGTGGCCTTCCTGCTCAGCACCGACGCCACC TTCATCACCGGGCAGACCATCCACGTCGACGGCGGGATCGGCTGCTTCCGATGA
Upstream 100 bases:
>100_bases ATCCGGACGGAACACCGGTCGAGTTCATCCAACTACCGGGCGGGGCGCGCAGCACCTACGAGATGCATCGCGGCGTGCGA CTGCGGCTGGGGCCGGTCAC
Downstream 100 bases:
>100_bases CACCGGAATCGCTGCGTGACCGGCAGCGCGCACAGATCCGGGCCGACATCCGGCGCGCGGCGTTCCGGTTGTTCGTCGAG CGCGGGTACGATGCGGTGAC
Product: hypothetical protein
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 257; Mature: 256
Protein sequence:
>257_residues MSYSHPDSMRGQVAIVTGAAQGVGKGIAAALLERGAAVLLVDIQQETLEATATELRALGRVERLVTDLRDPDSAPRIAAA AVDAFGSVHGLVNNAIATNEPKAFVDITTDDLALGYEVGPRATFLLMQAVHPLLVKEGGGAIVNLGSGTGTGGEPRWGGY AAAKEGIRGLSKVAALEWGRDNIRVNVVCPFAESDGVKLWKQFAPNDYAKAVGRVPMKRIGDVRTDVGALVAFLLSTDAT FITGQTIHVDGGIGCFR
Sequences:
>Translated_257_residues MSYSHPDSMRGQVAIVTGAAQGVGKGIAAALLERGAAVLLVDIQQETLEATATELRALGRVERLVTDLRDPDSAPRIAAA AVDAFGSVHGLVNNAIATNEPKAFVDITTDDLALGYEVGPRATFLLMQAVHPLLVKEGGGAIVNLGSGTGTGGEPRWGGY AAAKEGIRGLSKVAALEWGRDNIRVNVVCPFAESDGVKLWKQFAPNDYAKAVGRVPMKRIGDVRTDVGALVAFLLSTDAT FITGQTIHVDGGIGCFR >Mature_256_residues SYSHPDSMRGQVAIVTGAAQGVGKGIAAALLERGAAVLLVDIQQETLEATATELRALGRVERLVTDLRDPDSAPRIAAAA VDAFGSVHGLVNNAIATNEPKAFVDITTDDLALGYEVGPRATFLLMQAVHPLLVKEGGGAIVNLGSGTGTGGEPRWGGYA AAKEGIRGLSKVAALEWGRDNIRVNVVCPFAESDGVKLWKQFAPNDYAKAVGRVPMKRIGDVRTDVGALVAFLLSTDATF ITGQTIHVDGGIGCFR
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=35.1351351351351, Blast_Score=130, Evalue=8e-31, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=30.1204819277108, Blast_Score=100, Evalue=9e-22, Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=32.9317269076305, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=28.8973384030418, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI10190704, Length=270, Percent_Identity=27.037037037037, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=28.8065843621399, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI4504505, Length=214, Percent_Identity=28.9719626168224, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI4503301, Length=264, Percent_Identity=28.4090909090909, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI126723750, Length=256, Percent_Identity=27.34375, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI210032110, Length=218, Percent_Identity=25.6880733944954, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI40807363, Length=193, Percent_Identity=26.9430051813472, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI31542939, Length=187, Percent_Identity=32.0855614973262, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=1e-11, Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=34.7490347490347, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=34.9397590361446, Blast_Score=111, Evalue=5e-26, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=31.7269076305221, Blast_Score=107, Evalue=7e-25, Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=31.3492063492063, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=27.7551020408163, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=31.0204081632653, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1790717, Length=262, Percent_Identity=28.2442748091603, Blast_Score=77, Evalue=9e-16, Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=29.1187739463602, Blast_Score=67, Evalue=8e-13, Organism=Escherichia coli, GI1787526, Length=196, Percent_Identity=31.1224489795918, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=28.6852589641434, Blast_Score=61, Evalue=7e-11, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=26, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=29.1828793774319, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=32.3770491803279, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=29.8387096774194, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=30.3501945525292, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=29.4736842105263, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=27.3092369477912, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=29.2490118577075, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=26.2962962962963, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=28.4644194756554, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=27.7566539923954, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=26.615969581749, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17531453, Length=257, Percent_Identity=28.0155642023346, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=27.0676691729323, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=27.9693486590038, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17568967, Length=209, Percent_Identity=28.2296650717703, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=28.3018867924528, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17536651, Length=257, Percent_Identity=25.2918287937743, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=28.2868525896414, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17563726, Length=256, Percent_Identity=28.90625, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17536025, Length=279, Percent_Identity=25.8064516129032, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=28.030303030303, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17564282, Length=188, Percent_Identity=25.531914893617, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17567345, Length=188, Percent_Identity=26.5957446808511, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=26.7441860465116, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=28.4974093264249, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=262, Percent_Identity=29.0076335877863, Blast_Score=80, Evalue=3e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-12, Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=31.6205533596838, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=28.2258064516129, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI18859837, Length=193, Percent_Identity=32.1243523316062, Blast_Score=82, Evalue=2e-16, Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=32.5396825396825, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=30.4347826086957, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=28.2868525896414, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24640492, Length=197, Percent_Identity=25.3807106598985, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24584744, Length=214, Percent_Identity=30.3738317757009, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI28574402, Length=214, Percent_Identity=30.3738317757009, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24584748, Length=210, Percent_Identity=27.6190476190476, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI161076933, Length=210, Percent_Identity=27.6190476190476, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI21357673, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26834; Mature: 26703
Theoretical pI: Translated: 6.13; Mature: 6.13
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSYSHPDSMRGQVAIVTGAAQGVGKGIAAALLERGAAVLLVDIQQETLEATATELRALGR CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHH VERLVTDLRDPDSAPRIAAAAVDAFGSVHGLVNNAIATNEPKAFVDITTDDLALGYEVGP HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEECEECCC RATFLLMQAVHPLLVKEGGGAIVNLGSGTGTGGEPRWGGYAAAKEGIRGLSKVAALEWGR HHHHHHHHHHHHHEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC DNIRVNVVCPFAESDGVKLWKQFAPNDYAKAVGRVPMKRIGDVRTDVGALVAFLLSTDAT CCEEEEEEEECCCCCCHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCE FITGQTIHVDGGIGCFR EEECCEEEECCCCCCCC >Mature Secondary Structure SYSHPDSMRGQVAIVTGAAQGVGKGIAAALLERGAAVLLVDIQQETLEATATELRALGR CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHH VERLVTDLRDPDSAPRIAAAAVDAFGSVHGLVNNAIATNEPKAFVDITTDDLALGYEVGP HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEECEECCC RATFLLMQAVHPLLVKEGGGAIVNLGSGTGTGGEPRWGGYAAAKEGIRGLSKVAALEWGR HHHHHHHHHHHHHEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC DNIRVNVVCPFAESDGVKLWKQFAPNDYAKAVGRVPMKRIGDVRTDVGALVAFLLSTDAT CCEEEEEEEECCCCCCHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCE FITGQTIHVDGGIGCFR EEECCEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]