| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
Click here to switch to the map view.
The map label for this gene is dnaN
Identifier: 41406100
GI number: 41406100
Start: 2100
End: 3299
Strand: Direct
Name: dnaN
Synonym: MAP0002
Alternate gene names: 41406100
Gene position: 2100-3299 (Clockwise)
Preceding gene: 41406099
Following gene: 41406101
Centisome position: 0.04
GC content: 68.92
Gene sequence:
>1200_bases ATGGACGCGGCGACGACAACGGCTGGCCTCAGCGACTTGAAGTTTCGTTTAGTGCGGGAGTCTTTCGCCGACGCGGTGTC GTGGGTGGCCAAGAGCTTGCCGTCGCGACCCGCGGTGCCGGTGCTCTCCGGGGTGCTGCTGTCCGGCACCGACGAGGGGC TCACCATTTCCGGATTCGACTACGAGGTTTCCGCCGAAGCACAGGTGGCGGCCGAAATCGCGTCTCCGGGAAGTGTTTTG GTATCCGGGCGGTTGCTGTCTGACATCGTTCGGGCGCTGCCCAACAAGCCGATCGACTTCTACGTCGACGGCAATCGGGT GGCGTTGAACTGCGGAAGCGCCCGGTTCTCGCTGCCGACGATGGCCGTCGAGGATTACCCGACGCTGCCCACGCTGCCCG AGGAGACCGGGACGCTGCCGGCCGATCTGTTCGCCGAGGCGATCGGGCAGGTCGCGATCGCGGCCGGCCGCGACGACACC TTGCCCATGTTGACCGGAATCCGGGTCGAGATTTCCGGGGACACGGTGGTTTTGGCCGCCACCGACCGGTTCCGGCTGGC GGTTCGCGAGCTGACCTGGTCGGCGGCCTCCCCCGACATCGAAGCGGCGGTCCTGGTGCCGGCCAAGACGCTGGCCGAGG CGGCGCGGACCGGCATCGACGGTTCCGACGTGCGGCTGTCGCTGGGGGCGGGCGCGGGTGTCGGCAAGGATGGCCTGCTG GGTATCAGCGGCAACGGCAAGCGCAGCACCACCCGCCTGCTGGACGCGGAATTCCCGAAGTTCCGCCAGCTGTTGCCGGC TGAGCACACGGCGGTGGCCACCATCAACGTCGCCGAGCTGACCGAGGCCATCAAGCTGGTGGCGCTGGTGGCCGACCGGG GCGCGCAGGTGCGGATGGAATTCAGCGAGGGGTCGCTGCGGCTGTCCGCCGGCGCCGACGATGTCGGCCGGGCCGAGGAG GATCTGGCCGTGGATTTCGCCGGCGAACCGCTGACGATCGCGTTCAACCCCACGTATCTGACCGACGGACTGGGATCGGT GCGCTCCGAACGGGTGTCGTTCGGCTTCACCACCCCGGGCAAGCCCGCACTGCTGCGCCCGGCGTCCGACGACGACAGCC CGCCGAGCGGCAGCGGGCCGTTCAGCGCGCTGCCCACCGATTACGTCTACCTGCTGATGCCCGTGCGGTTGCCAGGCTAG
Upstream 100 bases:
>100_bases CGTCGACGCCTCGCGTGTCGCCGGCGCCGTGACGGGCCCCATGCTAGCGGGGGGAGGCTAGCCAATGGATCCGACAACGC TGAGTAGGTGAAGGGACGCT
Downstream 100 bases:
>100_bases GTGTACGTCCGGCATTTAGGACTGCGCGACTTCCGGTCCTGGGCACACGCCGACCTCGAACTGCAGCCGGGTCGGACGGT CTTCATCGGGTCCAACGGCT
Product: DNA polymerase III subunit beta
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 399; Mature: 399
Protein sequence:
>399_residues MDAATTTAGLSDLKFRLVRESFADAVSWVAKSLPSRPAVPVLSGVLLSGTDEGLTISGFDYEVSAEAQVAAEIASPGSVL VSGRLLSDIVRALPNKPIDFYVDGNRVALNCGSARFSLPTMAVEDYPTLPTLPEETGTLPADLFAEAIGQVAIAAGRDDT LPMLTGIRVEISGDTVVLAATDRFRLAVRELTWSAASPDIEAAVLVPAKTLAEAARTGIDGSDVRLSLGAGAGVGKDGLL GISGNGKRSTTRLLDAEFPKFRQLLPAEHTAVATINVAELTEAIKLVALVADRGAQVRMEFSEGSLRLSAGADDVGRAEE DLAVDFAGEPLTIAFNPTYLTDGLGSVRSERVSFGFTTPGKPALLRPASDDDSPPSGSGPFSALPTDYVYLLMPVRLPG
Sequences:
>Translated_399_residues MDAATTTAGLSDLKFRLVRESFADAVSWVAKSLPSRPAVPVLSGVLLSGTDEGLTISGFDYEVSAEAQVAAEIASPGSVL VSGRLLSDIVRALPNKPIDFYVDGNRVALNCGSARFSLPTMAVEDYPTLPTLPEETGTLPADLFAEAIGQVAIAAGRDDT LPMLTGIRVEISGDTVVLAATDRFRLAVRELTWSAASPDIEAAVLVPAKTLAEAARTGIDGSDVRLSLGAGAGVGKDGLL GISGNGKRSTTRLLDAEFPKFRQLLPAEHTAVATINVAELTEAIKLVALVADRGAQVRMEFSEGSLRLSAGADDVGRAEE DLAVDFAGEPLTIAFNPTYLTDGLGSVRSERVSFGFTTPGKPALLRPASDDDSPPSGSGPFSALPTDYVYLLMPVRLPG >Mature_399_residues MDAATTTAGLSDLKFRLVRESFADAVSWVAKSLPSRPAVPVLSGVLLSGTDEGLTISGFDYEVSAEAQVAAEIASPGSVL VSGRLLSDIVRALPNKPIDFYVDGNRVALNCGSARFSLPTMAVEDYPTLPTLPEETGTLPADLFAEAIGQVAIAAGRDDT LPMLTGIRVEISGDTVVLAATDRFRLAVRELTWSAASPDIEAAVLVPAKTLAEAARTGIDGSDVRLSLGAGAGVGKDGLL GISGNGKRSTTRLLDAEFPKFRQLLPAEHTAVATINVAELTEAIKLVALVADRGAQVRMEFSEGSLRLSAGADDVGRAEE DLAVDFAGEPLTIAFNPTYLTDGLGSVRSERVSFGFTTPGKPALLRPASDDDSPPSGSGPFSALPTDYVYLLMPVRLPG
Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped
COG id: COG0592
COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)
Gene ontology:
Cell location: Cytoplasm
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
Organism=Escherichia coli, GI1790136, Length=354, Percent_Identity=29.9435028248588, Blast_Score=133, Evalue=2e-32,
Paralogues:
None
Copy number: 5954 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]
Swissprot (AC and ID): DPO3B_MYCPA (Q9L7L6)
Other databases:
- EMBL: AF222789 - EMBL: AE016958 - RefSeq: NP_958936.1 - ProteinModelPortal: Q9L7L6 - SMR: Q9L7L6 - EnsemblBacteria: EBMYCT00000038154 - GeneID: 2719961 - GenomeReviews: AE016958_GR - KEGG: mpa:MAP0002 - NMPDR: fig|262316.1.peg.2 - GeneTree: EBGT00050000015837 - HOGENOM: HBG292442 - OMA: DYNRVIP - ProtClustDB: PRK07761 - BRENDA: 2.7.7.7 - GO: GO:0005737 - InterPro: IPR001001 - InterPro: IPR022635 - InterPro: IPR022637 - InterPro: IPR022634 - Gene3D: G3DSA:3.10.150.10 - SMART: SM00480 - TIGRFAMs: TIGR00663
Pfam domain/function: PF00712 DNA_pol3_beta; PF02767 DNA_pol3_beta_2; PF02768 DNA_pol3_beta_3
EC number: =2.7.7.7
Molecular weight: Translated: 41570; Mature: 41570
Theoretical pI: Translated: 4.31; Mature: 4.31
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.5 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 1.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDAATTTAGLSDLKFRLVRESFADAVSWVAKSLPSRPAVPVLSGVLLSGTDEGLTISGFD CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEECCCCCEEEECCC YEVSAEAQVAAEIASPGSVLVSGRLLSDIVRALPNKPIDFYVDGNRVALNCGSARFSLPT EEECCCHHEEHHHCCCCCEEEECHHHHHHHHHCCCCCEEEEECCCEEEEEECCCEECCCE MAVEDYPTLPTLPEETGTLPADLFAEAIGQVAIAAGRDDTLPMLTGIRVEISGDTVVLAA EEECCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCEEECEEEEECCCEEEEEE TDRFRLAVRELTWSAASPDIEAAVLVPAKTLAEAARTGIDGSDVRLSLGAGAGVGKDGLL CCHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEE GISGNGKRSTTRLLDAEFPKFRQLLPAEHTAVATINVAELTEAIKLVALVADRGAQVRME EECCCCCCCHHHHHCCCCHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEEEE FSEGSLRLSAGADDVGRAEEDLAVDFAGEPLTIAFNPTYLTDGLGSVRSERVSFGFTTPG ECCCCEEEECCCCCCCCCCCCEEEEECCCCEEEEECCCEECCCHHHHHHHHEEECCCCCC KPALLRPASDDDSPPSGSGPFSALPTDYVYLLMPVRLPG CCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCC >Mature Secondary Structure MDAATTTAGLSDLKFRLVRESFADAVSWVAKSLPSRPAVPVLSGVLLSGTDEGLTISGFD CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEECCCCCEEEECCC YEVSAEAQVAAEIASPGSVLVSGRLLSDIVRALPNKPIDFYVDGNRVALNCGSARFSLPT EEECCCHHEEHHHCCCCCEEEECHHHHHHHHHCCCCCEEEEECCCEEEEEECCCEECCCE MAVEDYPTLPTLPEETGTLPADLFAEAIGQVAIAAGRDDTLPMLTGIRVEISGDTVVLAA EEECCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCEEECEEEEECCCEEEEEE TDRFRLAVRELTWSAASPDIEAAVLVPAKTLAEAARTGIDGSDVRLSLGAGAGVGKDGLL CCHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEE GISGNGKRSTTRLLDAEFPKFRQLLPAEHTAVATINVAELTEAIKLVALVADRGAQVRME EECCCCCCCHHHHHCCCCHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCEEEEE FSEGSLRLSAGADDVGRAEEDLAVDFAGEPLTIAFNPTYLTDGLGSVRSERVSFGFTTPG ECCCCEEEECCCCCCCCCCCCEEEEECCCCEEEEECCCEECCCHHHHHHHHEEECCCCCC KPALLRPASDDDSPPSGSGPFSALPTDYVYLLMPVRLPG CCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA