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The map label for this gene is yecS [H]

Identifier: 39998494

GI number: 39998494

Start: 3747189

End: 3747980

Strand: Reverse

Name: yecS [H]

Synonym: GSU3405

Alternate gene names: 39998494

Gene position: 3747980-3747189 (Counterclockwise)

Preceding gene: 39998495

Following gene: 39998493

Centisome position: 98.27

GC content: 58.96

Gene sequence:

>792_bases
ATGGTTGATCAGGACAGGGTACGGCCGGCGGTTGTCGAGGTCGGTGACGGCGCAGCTATTCCGAGCAAAAGCGACATCGG
GCTTTTCACTGCCTGGCGCATCGCCTTTGTCGGCGCGATCGGCATTCTGGTCGTTCTGACAATCACGAAGCCGGATCCCT
ATCTCAACATCCTCAAGTTCGTTCCCGACGGTATCCTGGTCACCTTCCAGGTTACCGTCGGGGCCATTCTCCTCGCTTTG
GTCATCGGTCTTGTGGCCGGCCTTGGGCGCATCTCCTCCAACCGGATCATCAACGGCATCGCCTCTCTCTACGTGGAGAT
CATCCGCGGCATTCCGCTGCTGGTTCAACTCTTTTACATCTACTACGCCCTGGGCCGCTTCGTCCATGTCCCCGACATGG
CAAGCGCCATCATCGCCATGGCCGTCTGTTACGGTGCCTACATGGGCGAGGTGATCAGGGCCGGCATCCAGTCGATTCCC
AAGGGGCAGATGGAGGCGGCCCGTTCCCTCGGCATGACCAAGGGGCAGGCCATGCGCCACGTGATCCTGCCCCAGGCCGC
CAAAGTCGTGCTCCCCCCCATCGGTAACGAATTCATCGCTCTACTCAAGGATTCCTCGCTGGTGTCCATACTGGCGGTTG
CCGATATCCTGCGCCGGGGACGGGAGTTCGCCTCGGAGAGCTTCACCTATTTCGAGACCTATACGGTCATTGCCCTCGTC
TATTTGATCATTACCCTCTTCTTGTCAAAGCTTATCGGAATCATGGAGGAACGGATCAGTGCGGGGAGCTGA

Upstream 100 bases:

>100_bases
AAAGGGCGACAAGGAATTGCTCGCTCTGATCAACAAGGGCATCAAGGCCGTCAAGGCCAAGAAAGTTGACGAGCAACTCC
GGAAGAAGTGGCTCAGATAA

Downstream 100 bases:

>100_bases
GCGGGGCGGTATGGTAGAAGTACGCGACGTCAGCAAGAACTTCGGCGGGCTCAGGGCCCTCGACCGGGTAACGTTTGACG
TGAAGGAAGGAGAGAAGGTG

Product: amino acid ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MVDQDRVRPAVVEVGDGAAIPSKSDIGLFTAWRIAFVGAIGILVVLTITKPDPYLNILKFVPDGILVTFQVTVGAILLAL
VIGLVAGLGRISSNRIINGIASLYVEIIRGIPLLVQLFYIYYALGRFVHVPDMASAIIAMAVCYGAYMGEVIRAGIQSIP
KGQMEAARSLGMTKGQAMRHVILPQAAKVVLPPIGNEFIALLKDSSLVSILAVADILRRGREFASESFTYFETYTVIALV
YLIITLFLSKLIGIMEERISAGS

Sequences:

>Translated_263_residues
MVDQDRVRPAVVEVGDGAAIPSKSDIGLFTAWRIAFVGAIGILVVLTITKPDPYLNILKFVPDGILVTFQVTVGAILLAL
VIGLVAGLGRISSNRIINGIASLYVEIIRGIPLLVQLFYIYYALGRFVHVPDMASAIIAMAVCYGAYMGEVIRAGIQSIP
KGQMEAARSLGMTKGQAMRHVILPQAAKVVLPPIGNEFIALLKDSSLVSILAVADILRRGREFASESFTYFETYTVIALV
YLIITLFLSKLIGIMEERISAGS
>Mature_263_residues
MVDQDRVRPAVVEVGDGAAIPSKSDIGLFTAWRIAFVGAIGILVVLTITKPDPYLNILKFVPDGILVTFQVTVGAILLAL
VIGLVAGLGRISSNRIINGIASLYVEIIRGIPLLVQLFYIYYALGRFVHVPDMASAIIAMAVCYGAYMGEVIRAGIQSIP
KGQMEAARSLGMTKGQAMRHVILPQAAKVVLPPIGNEFIALLKDSSLVSILAVADILRRGREFASESFTYFETYTVIALV
YLIITLFLSKLIGIMEERISAGS

Specific function: Probably part of the binding-protein-dependent transport system yecCS for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=207, Percent_Identity=38.6473429951691, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1787030, Length=201, Percent_Identity=36.318407960199, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788646, Length=213, Percent_Identity=31.4553990610329, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1786874, Length=216, Percent_Identity=29.1666666666667, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1786873, Length=210, Percent_Identity=33.8095238095238, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788645, Length=220, Percent_Identity=29.5454545454545, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI87082239, Length=192, Percent_Identity=33.8541666666667, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787087, Length=211, Percent_Identity=28.9099526066351, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI48994930, Length=170, Percent_Identity=34.7058823529412, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787086, Length=221, Percent_Identity=23.5294117647059, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28355; Mature: 28355

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDQDRVRPAVVEVGDGAAIPSKSDIGLFTAWRIAFVGAIGILVVLTITKPDPYLNILKF
CCCCHHCCHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHH
VPDGILVTFQVTVGAILLALVIGLVAGLGRISSNRIINGIASLYVEIIRGIPLLVQLFYI
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHH
YYALGRFVHVPDMASAIIAMAVCYGAYMGEVIRAGIQSIPKGQMEAARSLGMTKGQAMRH
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHH
VILPQAAKVVLPPIGNEFIALLKDSSLVSILAVADILRRGREFASESFTYFETYTVIALV
HHCCHHHHEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
YLIITLFLSKLIGIMEERISAGS
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVDQDRVRPAVVEVGDGAAIPSKSDIGLFTAWRIAFVGAIGILVVLTITKPDPYLNILKF
CCCCHHCCHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHH
VPDGILVTFQVTVGAILLALVIGLVAGLGRISSNRIINGIASLYVEIIRGIPLLVQLFYI
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHH
YYALGRFVHVPDMASAIIAMAVCYGAYMGEVIRAGIQSIPKGQMEAARSLGMTKGQAMRH
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHH
VILPQAAKVVLPPIGNEFIALLKDSSLVSILAVADILRRGREFASESFTYFETYTVIALV
HHCCHHHHEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
YLIITLFLSKLIGIMEERISAGS
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]