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The map label for this gene is glnS [H]

Identifier: 39998455

GI number: 39998455

Start: 3699097

End: 3700761

Strand: Reverse

Name: glnS [H]

Synonym: GSU3366

Alternate gene names: 39998455

Gene position: 3700761-3699097 (Counterclockwise)

Preceding gene: 39998456

Following gene: 39998454

Centisome position: 97.03

GC content: 62.46

Gene sequence:

>1665_bases
ATGTCGACCACCGAACCAGCCCACGTCACCAACTTCCTGCGAACCATCGTCGAGGATGATCTCAAAAGCGGCAAGCACCG
GACTATCGTCACCCGTTTCCCGCCCGAGCCCAATGGCTATCTCCACATCGGCCACGCCAAATCCATCTGCCTTAACTTCG
GGCTGGCGCGGGATTTCGGCGGACGCTGCCATCTCCGCTTCGACGACACCAACCCGGTGAAAGAGGAGACCGAGTACATC
GAGTCGATCAAGGAGAGCGTCCGCTGGCTCGGCTTCGAGTGGGGGGAGCATTGCTATTACGCCTCCGACTACTTCGAGCA
GCTCTACCAGTGGGCCGAATCCCTCATCATACAGGGCAAGGCCTACGTAGACGACCTGACGGCCGATGAGATCCGCTCCT
ACCGCGGCACCCTCACCGAACCGGGCAAGGAGAGTCCCTCCCGCAGCCGCACTGCAGAGGAAAACCTTGATCTGTTCCGC
CGGATGCGGGCCGGCGAGTTCCCGGATGGGGCAAAGGTGTTAAGGGCCAGGATCGACATGGCCTCTCCCAACATCAACCT
GCGGGATCCGGTCATGTACCGGATTCTCCATGCCCCGCACCCCCATGCCGGCGACAAGTGGTGTATCTACCCGATGTATG
ACTACGCCCATGGCCAGTCGGACGCCATTGAGGGGATCACCCACTCTATCTGCACCCTGGAGTTCGAAGATCATAAGCCG
CTTTACGAGTGGTTTCTGGACAACCTGCCGGTGCCGAACCGGCCGCGCCAGTACGAGTTCGCCCGCCTGAATCTCACCTA
TGCGGTCATGAGCAAGCGCAAGCTCCTCCAGTTGGTTAAGGACGGCGATGTGACCGGCTGGGATGACCCGCGCATGCCGA
CCATCATGGGCATCCGCCGCCGGGGCTTCACGCCCGAGGCGATTCGGAATTTCTGCGACACCATCGGCGTGGGACGCAGC
GACAGCTGGATCGACATGAGCATTCTGGAAGAGAGCGTACGCCAGGATCTGAACGAGCGCGCGCCCCGGGTCATGGCGGT
CTTGCGGCCCCTTCGGCTGGTGATCGAAAACTATCCCGAGGGGGCGACGGAGGATCTCACCATTGCCTATCACCCCCAGC
GTCCCGACCTGGGGAGCCGGTCGGTCCCCTTTGGCCGGGAGCTTTTCATCGAGCGCGACGATTTCATGGAGGTCCCTCCC
AAGGGGTTCAAGCGTCTTTCGCCGGGCGAAGAAATCCGCCTGCGGGGCGCGTACATCGTGAAATGCACCGGGGTGGAGCG
TGATGGCGAGGGGAACGTGACCACGGTACGCTGCACCTATGATCCGGAGACCCGCAGCGGCCTTCCCGGCTCGGAGCGTA
AGGTCAAGGGGGTCATTCACTGGGTCTCGGCGACCCATGCCGTGACTGCCGAGGTCAGGCTTTACGACCGGCTCTTCACC
GTTCCCAACCCCTCGGGCGACGACTGGAAGGAGCTTCTCAATCCCCTGTCGGTGGAAATCGTTCGGGATTGCCGGCTGGA
GCCCTCCCTGGCTCTGGCCCGACCTGAGGATCGCTTCCAGTTCGAGCGTCAGGGATACTTCTGCGCTGACCGCGTCGATT
CGCAGCCCGGCGCGCCGGTCTTCAACCGGACCGTGACGCTGCGGGATTCGTGGGCCAAGAAGTAA

Upstream 100 bases:

>100_bases
AGAACTTGGGTTCGCGGGGCGTGGCGAGGGGATCGCCGCCTATGCGGTGGTGCTCATGGAAGAGAAATAGCAGCCCAAAG
AATTGCGCGAGGACAGCCTA

Downstream 100 bases:

>100_bases
TACGTAGAATTAAGAATCTGAAAGGGCTTTCCATGGCATTGCGCGTCTACAACACGCTTTCGGGCACAAAGGAAGATTTC
GTCACACTTGAGCCGGGCCG

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSTTEPAHVTNFLRTIVEDDLKSGKHRTIVTRFPPEPNGYLHIGHAKSICLNFGLARDFGGRCHLRFDDTNPVKEETEYI
ESIKESVRWLGFEWGEHCYYASDYFEQLYQWAESLIIQGKAYVDDLTADEIRSYRGTLTEPGKESPSRSRTAEENLDLFR
RMRAGEFPDGAKVLRARIDMASPNINLRDPVMYRILHAPHPHAGDKWCIYPMYDYAHGQSDAIEGITHSICTLEFEDHKP
LYEWFLDNLPVPNRPRQYEFARLNLTYAVMSKRKLLQLVKDGDVTGWDDPRMPTIMGIRRRGFTPEAIRNFCDTIGVGRS
DSWIDMSILEESVRQDLNERAPRVMAVLRPLRLVIENYPEGATEDLTIAYHPQRPDLGSRSVPFGRELFIERDDFMEVPP
KGFKRLSPGEEIRLRGAYIVKCTGVERDGEGNVTTVRCTYDPETRSGLPGSERKVKGVIHWVSATHAVTAEVRLYDRLFT
VPNPSGDDWKELLNPLSVEIVRDCRLEPSLALARPEDRFQFERQGYFCADRVDSQPGAPVFNRTVTLRDSWAKK

Sequences:

>Translated_554_residues
MSTTEPAHVTNFLRTIVEDDLKSGKHRTIVTRFPPEPNGYLHIGHAKSICLNFGLARDFGGRCHLRFDDTNPVKEETEYI
ESIKESVRWLGFEWGEHCYYASDYFEQLYQWAESLIIQGKAYVDDLTADEIRSYRGTLTEPGKESPSRSRTAEENLDLFR
RMRAGEFPDGAKVLRARIDMASPNINLRDPVMYRILHAPHPHAGDKWCIYPMYDYAHGQSDAIEGITHSICTLEFEDHKP
LYEWFLDNLPVPNRPRQYEFARLNLTYAVMSKRKLLQLVKDGDVTGWDDPRMPTIMGIRRRGFTPEAIRNFCDTIGVGRS
DSWIDMSILEESVRQDLNERAPRVMAVLRPLRLVIENYPEGATEDLTIAYHPQRPDLGSRSVPFGRELFIERDDFMEVPP
KGFKRLSPGEEIRLRGAYIVKCTGVERDGEGNVTTVRCTYDPETRSGLPGSERKVKGVIHWVSATHAVTAEVRLYDRLFT
VPNPSGDDWKELLNPLSVEIVRDCRLEPSLALARPEDRFQFERQGYFCADRVDSQPGAPVFNRTVTLRDSWAKK
>Mature_553_residues
STTEPAHVTNFLRTIVEDDLKSGKHRTIVTRFPPEPNGYLHIGHAKSICLNFGLARDFGGRCHLRFDDTNPVKEETEYIE
SIKESVRWLGFEWGEHCYYASDYFEQLYQWAESLIIQGKAYVDDLTADEIRSYRGTLTEPGKESPSRSRTAEENLDLFRR
MRAGEFPDGAKVLRARIDMASPNINLRDPVMYRILHAPHPHAGDKWCIYPMYDYAHGQSDAIEGITHSICTLEFEDHKPL
YEWFLDNLPVPNRPRQYEFARLNLTYAVMSKRKLLQLVKDGDVTGWDDPRMPTIMGIRRRGFTPEAIRNFCDTIGVGRSD
SWIDMSILEESVRQDLNERAPRVMAVLRPLRLVIENYPEGATEDLTIAYHPQRPDLGSRSVPFGRELFIERDDFMEVPPK
GFKRLSPGEEIRLRGAYIVKCTGVERDGEGNVTTVRCTYDPETRSGLPGSERKVKGVIHWVSATHAVTAEVRLYDRLFTV
PNPSGDDWKELLNPLSVEIVRDCRLEPSLALARPEDRFQFERQGYFCADRVDSQPGAPVFNRTVTLRDSWAKK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=554, Percent_Identity=45.6678700361011, Blast_Score=429, Evalue=1e-120,
Organism=Homo sapiens, GI62241042, Length=525, Percent_Identity=33.9047619047619, Blast_Score=282, Evalue=6e-76,
Organism=Escherichia coli, GI1786895, Length=554, Percent_Identity=60.6498194945848, Blast_Score=698, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=309, Percent_Identity=25.8899676375405, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=533, Percent_Identity=42.2138836772983, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17511007, Length=516, Percent_Identity=33.1395348837209, Blast_Score=263, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6324742, Length=573, Percent_Identity=41.0122164048866, Blast_Score=399, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6321192, Length=535, Percent_Identity=33.2710280373832, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6324540, Length=312, Percent_Identity=26.6025641025641, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17864488, Length=533, Percent_Identity=40.9005628517824, Blast_Score=387, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24649466, Length=426, Percent_Identity=35.2112676056338, Blast_Score=259, Evalue=4e-69,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 63680; Mature: 63548

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTEPAHVTNFLRTIVEDDLKSGKHRTIVTRFPPEPNGYLHIGHAKSICLNFGLARDFG
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCHHHHHHHCCHHHCCC
GRCHLRFDDTNPVKEETEYIESIKESVRWLGFEWGEHCYYASDYFEQLYQWAESLIIQGK
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCC
AYVDDLTADEIRSYRGTLTEPGKESPSRSRTAEENLDLFRRMRAGEFPDGAKVLRARIDM
HHHCCCCHHHHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ASPNINLRDPVMYRILHAPHPHAGDKWCIYPMYDYAHGQSDAIEGITHSICTLEFEDHKP
CCCCCCCCCHHHHHHHCCCCCCCCCCEEEEECHHCCCCCCHHHHHHHHCEEEEEECCCCC
LYEWFLDNLPVPNRPRQYEFARLNLTYAVMSKRKLLQLVKDGDVTGWDDPRMPTIMGIRR
HHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
RGFTPEAIRNFCDTIGVGRSDSWIDMSILEESVRQDLNERAPRVMAVLRPLRLVIENYPE
CCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GATEDLTIAYHPQRPDLGSRSVPFGRELFIERDDFMEVPPKGFKRLSPGEEIRLRGAYIV
CCCCCEEEEECCCCCCCCCCCCCCCHHEEEECCCCCCCCCHHHHCCCCCCEEEEECEEEE
KCTGVERDGEGNVTTVRCTYDPETRSGLPGSERKVKGVIHWVSATHAVTAEVRLYDRLFT
EEECCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEHEEE
VPNPSGDDWKELLNPLSVEIVRDCRLEPSLALARPEDRFQFERQGYFCADRVDSQPGAPV
CCCCCCHHHHHHHCHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCEEECCCCCCCCCCH
FNRTVTLRDSWAKK
HCCEEEECCCCCCC
>Mature Secondary Structure 
STTEPAHVTNFLRTIVEDDLKSGKHRTIVTRFPPEPNGYLHIGHAKSICLNFGLARDFG
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCHHHHHHHCCHHHCCC
GRCHLRFDDTNPVKEETEYIESIKESVRWLGFEWGEHCYYASDYFEQLYQWAESLIIQGK
CEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCC
AYVDDLTADEIRSYRGTLTEPGKESPSRSRTAEENLDLFRRMRAGEFPDGAKVLRARIDM
HHHCCCCHHHHHHHCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ASPNINLRDPVMYRILHAPHPHAGDKWCIYPMYDYAHGQSDAIEGITHSICTLEFEDHKP
CCCCCCCCCHHHHHHHCCCCCCCCCCEEEEECHHCCCCCCHHHHHHHHCEEEEEECCCCC
LYEWFLDNLPVPNRPRQYEFARLNLTYAVMSKRKLLQLVKDGDVTGWDDPRMPTIMGIRR
HHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
RGFTPEAIRNFCDTIGVGRSDSWIDMSILEESVRQDLNERAPRVMAVLRPLRLVIENYPE
CCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GATEDLTIAYHPQRPDLGSRSVPFGRELFIERDDFMEVPPKGFKRLSPGEEIRLRGAYIV
CCCCCEEEEECCCCCCCCCCCCCCCHHEEEECCCCCCCCCHHHHCCCCCCEEEEECEEEE
KCTGVERDGEGNVTTVRCTYDPETRSGLPGSERKVKGVIHWVSATHAVTAEVRLYDRLFT
EEECCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEHEEE
VPNPSGDDWKELLNPLSVEIVRDCRLEPSLALARPEDRFQFERQGYFCADRVDSQPGAPV
CCCCCCHHHHHHHCHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCCEEECCCCCCCCCCH
FNRTVTLRDSWAKK
HCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]