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The map label for this gene is obg

Identifier: 39998303

GI number: 39998303

Start: 3519000

End: 3520016

Strand: Reverse

Name: obg

Synonym: GSU3213

Alternate gene names: 39998303

Gene position: 3520016-3519000 (Counterclockwise)

Preceding gene: 39998304

Following gene: 39998302

Centisome position: 92.29

GC content: 64.6

Gene sequence:

>1017_bases
ATGCAGTTTATCGATGAAGTAAAAATACACGTTCAGTCGGGTCACGGCGGCGCCGGCTGCGTCTCTTTCCGCCGGGAAAA
GTTCATTCCCTTCGGCGGCCCCAACGGTGGCGACGGCGGTCGGGGCGGCGACGTTATCTTCCGGGTCGACTCGAACCTGT
CCACCCTGCTGGACCTGCGCTACCGGCCCCACCTGAAGGCCGGCTCCGGCAAGAACGGCATGGGCAAGGACCGCCACGGC
GCCGGCGGTGAGGACCTGGTCATTCCTGTCCCGCCGGGTACCATCATCAAGGATGCGGAAACCGGCGAGATCCTGGCCGA
CCTGGTGACGGCCGGTGAGGAAATCGTCTTGCTCAAGGGGGGACGGGGCGGCCAGGGCAACGCGCGGTTCGCCACCTCCA
CCAACCGGGCGCCCAAGTTCGCCCAGCCGGGCGAGCCCGAGGAGCAGCGGTGGCTGAGGCTGGAGCTGAAACTCCTGGCC
GATGTGGGGCTTCTGGGTTTCCCTAACGTGGGGAAATCTTCGTTCATCACGCGTGTTTCGGCGGCCCGACCCAAGATCGC
CGATTACCCGTTCACCACCCTGAAGCCGAACCTGGGGGTGGTTCCTTACAAGAACTACCGTTCCTTTGTCATCGCCGACA
TTCCGGGGATCATCGAAGGGGCCTCCGAGGGGGCGGGACTCGGCCATCGCTTCCTCAAGCACGTTGAACGGACCACCGTG
CTGCTCCACGTGCTCGACCTCTCGTGGATGCCCGACCGCGATCCCATTCGCGAGTACGAGGCCCTCAACCGGGAATTGGC
CCTCTTCAGTCCCGAGCTGGCCGACAAGCGCCAGATCGTGGTGGTCAACAAGATGGATCTCCCGGCGGTGAGAGAGAATC
TGCCTGCGGTGCTCCCCTGGTTCCGGGAGCGGGGCCTTGCGGTCTTTCCCCTCTCTGCCGCAACCGGCGAGGGGATTTCC
CCTTTGCTCGACGAAATCGCCCGCTCCCTCTGGGGCAAGGACGAGGAGGAGTGGTAG

Upstream 100 bases:

>100_bases
CTCCTTTCCATCGGCAGCCGACGCTGCCGATTTTTTTTGCCCGCCACCTGACGAATTCTGCTATAGTCTCTGTTTCATTT
CACGCATTTCACGGGAAGCC

Downstream 100 bases:

>100_bases
ACGGCGCTATGCGTAGCGGAATCCTCTCCAAGGTCAAGCGGATCGTCATCAAGATCGGCAGTGGGGTCCTCACCTGTGGG
GACAACGGGCTCAACAAGCC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MQFIDEVKIHVQSGHGGAGCVSFRREKFIPFGGPNGGDGGRGGDVIFRVDSNLSTLLDLRYRPHLKAGSGKNGMGKDRHG
AGGEDLVIPVPPGTIIKDAETGEILADLVTAGEEIVLLKGGRGGQGNARFATSTNRAPKFAQPGEPEEQRWLRLELKLLA
DVGLLGFPNVGKSSFITRVSAARPKIADYPFTTLKPNLGVVPYKNYRSFVIADIPGIIEGASEGAGLGHRFLKHVERTTV
LLHVLDLSWMPDRDPIREYEALNRELALFSPELADKRQIVVVNKMDLPAVRENLPAVLPWFRERGLAVFPLSAATGEGIS
PLLDEIARSLWGKDEEEW

Sequences:

>Translated_338_residues
MQFIDEVKIHVQSGHGGAGCVSFRREKFIPFGGPNGGDGGRGGDVIFRVDSNLSTLLDLRYRPHLKAGSGKNGMGKDRHG
AGGEDLVIPVPPGTIIKDAETGEILADLVTAGEEIVLLKGGRGGQGNARFATSTNRAPKFAQPGEPEEQRWLRLELKLLA
DVGLLGFPNVGKSSFITRVSAARPKIADYPFTTLKPNLGVVPYKNYRSFVIADIPGIIEGASEGAGLGHRFLKHVERTTV
LLHVLDLSWMPDRDPIREYEALNRELALFSPELADKRQIVVVNKMDLPAVRENLPAVLPWFRERGLAVFPLSAATGEGIS
PLLDEIARSLWGKDEEEW
>Mature_338_residues
MQFIDEVKIHVQSGHGGAGCVSFRREKFIPFGGPNGGDGGRGGDVIFRVDSNLSTLLDLRYRPHLKAGSGKNGMGKDRHG
AGGEDLVIPVPPGTIIKDAETGEILADLVTAGEEIVLLKGGRGGQGNARFATSTNRAPKFAQPGEPEEQRWLRLELKLLA
DVGLLGFPNVGKSSFITRVSAARPKIADYPFTTLKPNLGVVPYKNYRSFVIADIPGIIEGASEGAGLGHRFLKHVERTTV
LLHVLDLSWMPDRDPIREYEALNRELALFSPELADKRQIVVVNKMDLPAVRENLPAVLPWFRERGLAVFPLSAATGEGIS
PLLDEIARSLWGKDEEEW

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=321, Percent_Identity=43.9252336448598, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI111955139, Length=362, Percent_Identity=36.7403314917127, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI111955063, Length=195, Percent_Identity=39.4871794871795, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI58761500, Length=153, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4557537, Length=87, Percent_Identity=40.2298850574713, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4758796, Length=88, Percent_Identity=38.6363636363636, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789574, Length=329, Percent_Identity=50.1519756838906, Blast_Score=267, Evalue=6e-73,
Organism=Escherichia coli, GI1787454, Length=131, Percent_Identity=32.824427480916, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508313, Length=332, Percent_Identity=38.2530120481928, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17552324, Length=312, Percent_Identity=31.0897435897436, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=33.59375, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=101, Percent_Identity=36.6336633663366, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71981008, Length=123, Percent_Identity=34.1463414634146, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25145602, Length=184, Percent_Identity=31.5217391304348, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25145600, Length=184, Percent_Identity=31.5217391304348, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=164, Percent_Identity=39.6341463414634, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321612, Length=89, Percent_Identity=40.4494382022472, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319281, Length=108, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319499, Length=141, Percent_Identity=35.4609929078014, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129375, Length=330, Percent_Identity=41.2121212121212, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24585318, Length=363, Percent_Identity=32.5068870523416, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24640873, Length=134, Percent_Identity=31.3432835820896, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640877, Length=134, Percent_Identity=31.3432835820896, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640875, Length=134, Percent_Identity=31.3432835820896, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356473, Length=107, Percent_Identity=36.4485981308411, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_GEOSL (Q747Q2)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_954254.1
- HSSP:   P20964
- ProteinModelPortal:   Q747Q2
- SMR:   Q747Q2
- GeneID:   2688315
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU3213
- NMPDR:   fig|243231.1.peg.3192
- TIGR:   GSU3213
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- ProtClustDB:   PRK12299
- BioCyc:   GSUL243231:GSU_3213-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36827; Mature: 36827

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFIDEVKIHVQSGHGGAGCVSFRREKFIPFGGPNGGDGGRGGDVIFRVDSNLSTLLDLR
CCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHH
YRPHLKAGSGKNGMGKDRHGAGGEDLVIPVPPGTIIKDAETGEILADLVTAGEEIVLLKG
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCHHHHHHHHHHCCCEEEEEEC
GRGGQGNARFATSTNRAPKFAQPGEPEEQRWLRLELKLLADVGLLGFPNVGKSSFITRVS
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AARPKIADYPFTTLKPNLGVVPYKNYRSFVIADIPGIIEGASEGAGLGHRFLKHVERTTV
HCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHVLDLSWMPDRDPIREYEALNRELALFSPELADKRQIVVVNKMDLPAVRENLPAVLPW
HHHHHHCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCHHHHCCCHHHHH
FRERGLAVFPLSAATGEGISPLLDEIARSLWGKDEEEW
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQFIDEVKIHVQSGHGGAGCVSFRREKFIPFGGPNGGDGGRGGDVIFRVDSNLSTLLDLR
CCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHH
YRPHLKAGSGKNGMGKDRHGAGGEDLVIPVPPGTIIKDAETGEILADLVTAGEEIVLLKG
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCHHHHHHHHHHCCCEEEEEEC
GRGGQGNARFATSTNRAPKFAQPGEPEEQRWLRLELKLLADVGLLGFPNVGKSSFITRVS
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
AARPKIADYPFTTLKPNLGVVPYKNYRSFVIADIPGIIEGASEGAGLGHRFLKHVERTTV
HCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHHHHH
LLHVLDLSWMPDRDPIREYEALNRELALFSPELADKRQIVVVNKMDLPAVRENLPAVLPW
HHHHHHCCCCCCCCHHHHHHHHCCEEEEECCCCCCCCEEEEEECCCCCHHHHCCCHHHHH
FRERGLAVFPLSAATGEGISPLLDEIARSLWGKDEEEW
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA