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The map label for this gene is lolA [H]

Identifier: 39998293

GI number: 39998293

Start: 3509921

End: 3510649

Strand: Direct

Name: lolA [H]

Synonym: GSU3203

Alternate gene names: 39998293

Gene position: 3509921-3510649 (Clockwise)

Preceding gene: 39998292

Following gene: 39998294

Centisome position: 92.02

GC content: 61.59

Gene sequence:

>729_bases
ATGACTCTGCCGCGCATACTATTGCTGTTTGCCGTCACCCTGCTTCTGGGGACAGGTGCCGCCACGGCGGCGCCGTCAGC
CCCCCTGGCCGACGTGGTAGCCACTTTGGAACAGGGATACGCTTCCCTCAAGGACCTGCAGGCATCCTTCACCCAACGGA
CCGAAATGGCGGCGGTCAAGCGGTCCCAGACCGGCTCCGGCGAGCTGTTCATCCGCAAAGGTGCCGGCGACCGGGCGCTC
TTTCGCTTCAACTACGTCAAACCGTCCCAGCAGATCGTCTCCAACGGCAAGACCGTCTGGTACTATCTGCCCGAGAACCG
GCAGGTCATGACCATGGATGCCTCTGCCCTCTTTGCGGGCGGCGGGGGGGTCGCCCTTTCCTACCTGACCGGCATAGGCC
AGATATCGCGCGACTTCGCCGTAAGCTTTGCGGGCAACGGACGCGACGCCAAAGGGAACCACGTCCTGGACCTGGTGCCC
AAAAAACAGGGCCAGGCCTTTGCCCGGCTCCAGCTCACCGTTTCGGCCAAGGCGGTCGAAGAGTACCAACGGGCGGGCAA
AGCCACGGTACCCTTTCCCATCGTTTCATCTGTTGTGGTTGACCAGATGGGGAGCCGCACGTCCTTCGAATTCTCGAAAA
TACGGGTGAACCGTGGGCTGGCCGGTTCTCTCTTTACATTCAAGGCTCCTGCCGGCGTTGAGGTAATCCAGGCACCGGGA
GTCAAATAA

Upstream 100 bases:

>100_bases
CGGCGCTGACCCCGAATCTGGCTCAGGCGAGGGCGGCGTGACATATGCCGCCTCGCCCTTTTCAATCGCGTCATCCTTTG
AACAGAACGAGGACCGGAAC

Downstream 100 bases:

>100_bases
CATTATTCAGGGAGGAAACTATGCCCTCATTCGACATCGTCTCGAAGGTGGAAATGCAGGAGGTCGACAACGCGGTGAAC
CAGACCGTGAAAGAGATTTC

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTLPRILLLFAVTLLLGTGAATAAPSAPLADVVATLEQGYASLKDLQASFTQRTEMAAVKRSQTGSGELFIRKGAGDRAL
FRFNYVKPSQQIVSNGKTVWYYLPENRQVMTMDASALFAGGGGVALSYLTGIGQISRDFAVSFAGNGRDAKGNHVLDLVP
KKQGQAFARLQLTVSAKAVEEYQRAGKATVPFPIVSSVVVDQMGSRTSFEFSKIRVNRGLAGSLFTFKAPAGVEVIQAPG
VK

Sequences:

>Translated_242_residues
MTLPRILLLFAVTLLLGTGAATAAPSAPLADVVATLEQGYASLKDLQASFTQRTEMAAVKRSQTGSGELFIRKGAGDRAL
FRFNYVKPSQQIVSNGKTVWYYLPENRQVMTMDASALFAGGGGVALSYLTGIGQISRDFAVSFAGNGRDAKGNHVLDLVP
KKQGQAFARLQLTVSAKAVEEYQRAGKATVPFPIVSSVVVDQMGSRTSFEFSKIRVNRGLAGSLFTFKAPAGVEVIQAPG
VK
>Mature_241_residues
TLPRILLLFAVTLLLGTGAATAAPSAPLADVVATLEQGYASLKDLQASFTQRTEMAAVKRSQTGSGELFIRKGAGDRALF
RFNYVKPSQQIVSNGKTVWYYLPENRQVMTMDASALFAGGGGVALSYLTGIGQISRDFAVSFAGNGRDAKGNHVLDLVPK
KQGQAFARLQLTVSAKAVEEYQRAGKATVPFPIVSSVVVDQMGSRTSFEFSKIRVNRGLAGSLFTFKAPAGVEVIQAPGV
K

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 25738; Mature: 25607

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPRILLLFAVTLLLGTGAATAAPSAPLADVVATLEQGYASLKDLQASFTQRTEMAAVK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSQTGSGELFIRKGAGDRALFRFNYVKPSQQIVSNGKTVWYYLPENRQVMTMDASALFAG
HCCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHCCCEEEEEECCCCEEEEEECCEEEEC
GGGVALSYLTGIGQISRDFAVSFAGNGRDAKGNHVLDLVPKKQGQAFARLQLTVSAKAVE
CCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCCCCEEEEEEEEEHHHHHH
EYQRAGKATVPFPIVSSVVVDQMGSRTSFEFSKIRVNRGLAGSLFTFKAPAGVEVIQAPG
HHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEEEECCCCCEEECCCC
VK
CC
>Mature Secondary Structure 
TLPRILLLFAVTLLLGTGAATAAPSAPLADVVATLEQGYASLKDLQASFTQRTEMAAVK
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSQTGSGELFIRKGAGDRALFRFNYVKPSQQIVSNGKTVWYYLPENRQVMTMDASALFAG
HCCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHCCCEEEEEECCCCEEEEEECCEEEEC
GGGVALSYLTGIGQISRDFAVSFAGNGRDAKGNHVLDLVPKKQGQAFARLQLTVSAKAVE
CCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCCCCEEEEEEEEEHHHHHH
EYQRAGKATVPFPIVSSVVVDQMGSRTSFEFSKIRVNRGLAGSLFTFKAPAGVEVIQAPG
HHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCEEEEECCCCCEEECCCC
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA