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The map label for this gene is cheR [H]

Identifier: 39998285

GI number: 39998285

Start: 3503129

End: 3504052

Strand: Direct

Name: cheR [H]

Synonym: GSU3195

Alternate gene names: 39998285

Gene position: 3503129-3504052 (Clockwise)

Preceding gene: 39998284

Following gene: 39998286

Centisome position: 91.85

GC content: 58.12

Gene sequence:

>924_bases
TTGCTGTCTGTGGAAAGACGGATCAATCACCACATGATAAACAGGCACATGAACGAGCACAGACGGGTGAGCATCCCTCC
CGAGGAACCGGCCGGCGGCTTTTCGGACACGGCATTCTCACGCATACGCGACATCCTCTGCACAAGGCGAAATTTTGACA
TCGCCAGCTACAAGGACAAATACATCAAGCGCCGGATCTCCATCCGGATCAGGGCGACCCGGGCGGCAACGGTCGACGAC
TACTGCGATCTGCTCCAGCGGAGCGAAGAAGAACTGGACCTGCTGGTTAAAGGGCTGACTATTCATGTGAGTCAGTTCTT
CCGCAACCGATCCACCTTTGAAAAGCTCGGCACCGAGGTGTTCCCCGCGCTTTTTGCCCGACTGAGAGCCGAAGGGCGGG
AACACCTGACCCTGTGGAGCGCCGGATGCGCCGGAGGCGAGGAGCCGTTCACCCTGGCCCTCATCCTGGCAGAGCGGTTC
GCGAAGGAGTTGGAAGAGTTCAAGGTTTCCATCGTTGCGACCGATATAGATGATGGGATCCTTGAAGCGGCACAGCAGGG
GATGTATGGTCACGAACGTCTCCAGGAAGCCCCCGCTCACGTGCTCGACCGCCATTTTTGCCGTAACGGCGACAAATACT
GCCTCAGTCCGGCCATCCGCGGGATGGTGGAGTTTCGCCGCGGAGACCTCTTCGACACCGGAAACCATGTGGAGAGCGAT
CTGATCCTCTGCCGCAATGTTCTTATCTACTTTGAACGGCGGGAGCAGGAACGCATTCTTCTGGGGCTATCCAATGCCCT
CACCCAGGGCGGCATCCTGATCCTCGGCAAGGCCGAGACCCTCGTAGGAGAACTGCGGCGGCGCTTCGGGACCATCTGCC
CGGTGGAACGGATTTACACGAAGAATCGCTTTTCGGTATACTAA

Upstream 100 bases:

>100_bases
TATCCCTCCGAGACGCCGCGGCTTCAACCATTTCGCGCCGTAAATCCTGCGCCGGCCCACTGCCTCGCGGCATCGCGCGT
GCGCCGTCACGGAACACTTC

Downstream 100 bases:

>100_bases
CAGCCGTGATTTCCCCCCGACGACGTGCGGCTGCGGCGCCGTCGGCCAGTGGAGCGAGTATGCGCATCCCTCTTGGCTAC
AAGTTCATCCTCGGATTCGT

Product: chemotaxis protein methyltransferase CheR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MLSVERRINHHMINRHMNEHRRVSIPPEEPAGGFSDTAFSRIRDILCTRRNFDIASYKDKYIKRRISIRIRATRAATVDD
YCDLLQRSEEELDLLVKGLTIHVSQFFRNRSTFEKLGTEVFPALFARLRAEGREHLTLWSAGCAGGEEPFTLALILAERF
AKELEEFKVSIVATDIDDGILEAAQQGMYGHERLQEAPAHVLDRHFCRNGDKYCLSPAIRGMVEFRRGDLFDTGNHVESD
LILCRNVLIYFERREQERILLGLSNALTQGGILILGKAETLVGELRRRFGTICPVERIYTKNRFSVY

Sequences:

>Translated_307_residues
MLSVERRINHHMINRHMNEHRRVSIPPEEPAGGFSDTAFSRIRDILCTRRNFDIASYKDKYIKRRISIRIRATRAATVDD
YCDLLQRSEEELDLLVKGLTIHVSQFFRNRSTFEKLGTEVFPALFARLRAEGREHLTLWSAGCAGGEEPFTLALILAERF
AKELEEFKVSIVATDIDDGILEAAQQGMYGHERLQEAPAHVLDRHFCRNGDKYCLSPAIRGMVEFRRGDLFDTGNHVESD
LILCRNVLIYFERREQERILLGLSNALTQGGILILGKAETLVGELRRRFGTICPVERIYTKNRFSVY
>Mature_307_residues
MLSVERRINHHMINRHMNEHRRVSIPPEEPAGGFSDTAFSRIRDILCTRRNFDIASYKDKYIKRRISIRIRATRAATVDD
YCDLLQRSEEELDLLVKGLTIHVSQFFRNRSTFEKLGTEVFPALFARLRAEGREHLTLWSAGCAGGEEPFTLALILAERF
AKELEEFKVSIVATDIDDGILEAAQQGMYGHERLQEAPAHVLDRHFCRNGDKYCLSPAIRGMVEFRRGDLFDTGNHVESD
LILCRNVLIYFERREQERILLGLSNALTQGGILILGKAETLVGELRRRFGTICPVERIYTKNRFSVY

Specific function: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. CheR is responsible for the chemotactic adaptation to repellents [H]

COG id: COG1352

COG function: function code NT; Methylase of chemotaxis methyl-accepting proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheR-type methyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788193, Length=265, Percent_Identity=29.4339622641509, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022642
- InterPro:   IPR000780
- InterPro:   IPR022641 [H]

Pfam domain/function: PF01739 CheR; PF03705 CheR_N [H]

EC number: =2.1.1.80 [H]

Molecular weight: Translated: 35346; Mature: 35346

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS50123 CHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVERRINHHMINRHMNEHRRVSIPPEEPAGGFSDTAFSRIRDILCTRRNFDIASYKDK
CCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
YIKRRISIRIRATRAATVDDYCDLLQRSEEELDLLVKGLTIHVSQFFRNRSTFEKLGTEV
HHHHHHHEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
FPALFARLRAEGREHLTLWSAGCAGGEEPFTLALILAERFAKELEEFKVSIVATDIDDGI
HHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCHHH
LEAAQQGMYGHERLQEAPAHVLDRHFCRNGDKYCLSPAIRGMVEFRRGDLFDTGNHVESD
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCCCCHHHH
LILCRNVLIYFERREQERILLGLSNALTQGGILILGKAETLVGELRRRFGTICPVERIYT
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCCHHHHHC
KNRFSVY
CCCCCCC
>Mature Secondary Structure
MLSVERRINHHMINRHMNEHRRVSIPPEEPAGGFSDTAFSRIRDILCTRRNFDIASYKDK
CCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
YIKRRISIRIRATRAATVDDYCDLLQRSEEELDLLVKGLTIHVSQFFRNRSTFEKLGTEV
HHHHHHHEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
FPALFARLRAEGREHLTLWSAGCAGGEEPFTLALILAERFAKELEEFKVSIVATDIDDGI
HHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCHHH
LEAAQQGMYGHERLQEAPAHVLDRHFCRNGDKYCLSPAIRGMVEFRRGDLFDTGNHVESD
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCCCCCHHHH
LILCRNVLIYFERREQERILLGLSNALTQGGILILGKAETLVGELRRRFGTICPVERIYT
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCCHHHHHC
KNRFSVY
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8244966; 9384377; 10568751 [H]