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The map label for this gene is mhpC [C]

Identifier: 39998247

GI number: 39998247

Start: 3464329

End: 3465129

Strand: Direct

Name: mhpC [C]

Synonym: GSU3157

Alternate gene names: 39998247

Gene position: 3464329-3465129 (Clockwise)

Preceding gene: 39998246

Following gene: 39998249

Centisome position: 90.83

GC content: 66.54

Gene sequence:

>801_bases
ATGGAGGCACTCGTGAACGGCATCTCCCTCGCCTATGACGACCAGGGCAGCGGTCCGCCCCTGATCCTGATCCACGGCTT
TCCCCTCCAGAGAAAGATGTGGCATCCCCAGATCCAGGCAGTGACCGGCGCCGGCTTTCGCCTCGTGACCCCAGACCTGC
GGGGTTTCGGCGAATCGGATGCCCCGGACGGACCTTACTCAATGGAGATATTCGCCGACGACATCGTGGCGCTCATGGAT
CATCTGTCGATCGGGCAGGCGGTCATCGGCGGAATGTCCATGGGAGGCTACGTCCTCATGAACCTGCTGGAACGCTACCC
GGAGCGGGTTGCCGGGGCGTGCTTCATCGTGACCCGGGCGCCGGCCGACGACGAGGCGGGCAAGGCCCGGCGGCTGCACC
TGGCCCAGGAGGTGATGAAGTTCGGGCCTCAGCTGGTGGCGGACGCGTTTGTGGAAGTCCTCTTCGCCGAGCAGAACCTC
ACGGAGCGGCCGAAACTGGTTGAGGAGGTCTACGGGTGGATGAGCGCCACCGATTCGCGGGGGCTTGCGGGCGGGCTCCT
GGCCATGCGGGAGCGCACGGACTACGGCGCGCTTCTGGACCGGTTCCGGGTGCCGGCACTGGCCATCGGGGCCGAAGATG
ACCGGGCCATCCCGGCCGAATTCTCCCGGGCCATTGCCGCCGGCGTTCCGGGGTGCCGACTCTGTATCGTGCCCGAGGCA
GGGCATCTGGCCAATCTGGAGCATCCGGGGGCCTTCAACGACTGCCTGCTGGAATTCCTCACCTCGCTCGGCAGCTGGTA
G

Upstream 100 bases:

>100_bases
GGGCTTTTTTTTGCCCAGCCATCGAGGTTGTTGCCCCGCGACGGCGCATTGGTATATGGTTTTCCCATTGATCCAATGAC
GATTGAAAGGAGACTCCTCC

Downstream 100 bases:

>100_bases
CGGACATGAAAAAGCCCGCGGGATGCGGGCTGGTGGTGCAACGTCAGGCACATGCGCCTCTCAGGGAGGGCACTTGCCGC
AAACCGACCGGAACAGGACC

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: Chloride peroxidase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MEALVNGISLAYDDQGSGPPLILIHGFPLQRKMWHPQIQAVTGAGFRLVTPDLRGFGESDAPDGPYSMEIFADDIVALMD
HLSIGQAVIGGMSMGGYVLMNLLERYPERVAGACFIVTRAPADDEAGKARRLHLAQEVMKFGPQLVADAFVEVLFAEQNL
TERPKLVEEVYGWMSATDSRGLAGGLLAMRERTDYGALLDRFRVPALAIGAEDDRAIPAEFSRAIAAGVPGCRLCIVPEA
GHLANLEHPGAFNDCLLEFLTSLGSW

Sequences:

>Translated_266_residues
MEALVNGISLAYDDQGSGPPLILIHGFPLQRKMWHPQIQAVTGAGFRLVTPDLRGFGESDAPDGPYSMEIFADDIVALMD
HLSIGQAVIGGMSMGGYVLMNLLERYPERVAGACFIVTRAPADDEAGKARRLHLAQEVMKFGPQLVADAFVEVLFAEQNL
TERPKLVEEVYGWMSATDSRGLAGGLLAMRERTDYGALLDRFRVPALAIGAEDDRAIPAEFSRAIAAGVPGCRLCIVPEA
GHLANLEHPGAFNDCLLEFLTSLGSW
>Mature_266_residues
MEALVNGISLAYDDQGSGPPLILIHGFPLQRKMWHPQIQAVTGAGFRLVTPDLRGFGESDAPDGPYSMEIFADDIVALMD
HLSIGQAVIGGMSMGGYVLMNLLERYPERVAGACFIVTRAPADDEAGKARRLHLAQEVMKFGPQLVADAFVEVLFAEQNL
TERPKLVEEVYGWMSATDSRGLAGGLLAMRERTDYGALLDRFRVPALAIGAEDDRAIPAEFSRAIAAGVPGCRLCIVPEA
GHLANLEHPGAFNDCLLEFLTSLGSW

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial non-heme bromo- and chloro- peroxidases family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=297, Percent_Identity=27.6094276094276, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI145611434, Length=242, Percent_Identity=26.4462809917355, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI87081721, Length=275, Percent_Identity=23.6363636363636, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =1.11.1.10 [H]

Molecular weight: Translated: 28740; Mature: 28740

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALVNGISLAYDDQGSGPPLILIHGFPLQRKMWHPQIQAVTGAGFRLVTPDLRGFGESD
CCCHHCCCEEEECCCCCCCCEEEEECCCCHHHHCCCHHEEECCCCEEEECCHHHCCCCCC
APDGPYSMEIFADDIVALMDHLSIGQAVIGGMSMGGYVLMNLLERYPERVAGACFIVTRA
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEC
PADDEAGKARRLHLAQEVMKFGPQLVADAFVEVLFAEQNLTERPKLVEEVYGWMSATDSR
CCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
GLAGGLLAMRERTDYGALLDRFRVPALAIGAEDDRAIPAEFSRAIAAGVPGCRLCIVPEA
CCHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCC
GHLANLEHPGAFNDCLLEFLTSLGSW
CCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEALVNGISLAYDDQGSGPPLILIHGFPLQRKMWHPQIQAVTGAGFRLVTPDLRGFGESD
CCCHHCCCEEEECCCCCCCCEEEEECCCCHHHHCCCHHEEECCCCEEEECCHHHCCCCCC
APDGPYSMEIFADDIVALMDHLSIGQAVIGGMSMGGYVLMNLLERYPERVAGACFIVTRA
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEC
PADDEAGKARRLHLAQEVMKFGPQLVADAFVEVLFAEQNLTERPKLVEEVYGWMSATDSR
CCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
GLAGGLLAMRERTDYGALLDRFRVPALAIGAEDDRAIPAEFSRAIAAGVPGCRLCIVPEA
CCHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCC
GHLANLEHPGAFNDCLLEFLTSLGSW
CCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]