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The map label for this gene is aroF [H]

Identifier: 39998232

GI number: 39998232

Start: 3449646

End: 3450665

Strand: Reverse

Name: aroF [H]

Synonym: GSU3142

Alternate gene names: 39998232

Gene position: 3450665-3449646 (Counterclockwise)

Preceding gene: 39998235

Following gene: 39998231

Centisome position: 90.47

GC content: 62.35

Gene sequence:

>1020_bases
ATGATCATCGTCATGAAAGCGGGAGCGGCAAAAAAAGACCGGGACGAGGTAATCAGGCGGATCAGGGAGCTGGGCTACAA
GCCCCATGTCATCCATGGCACCACGCGGGACGTGATCGGGGCCGTGGGGGACGAGCGGGGCAAGTTGGTCCTTCAGGGCG
TCGAATCCATGCACGGCGTGGAGAGCGTGGTGCCGATCCTGAAGCCGTACAAGCTGGCATCAAGGGAGGTGAAGCCCGAA
CCGAGTGTTGTCGCCATTACGGATACCGTGGTCATCGGCGGCCCTGAAGTCATTGTCATGGCCGGTCCCTGTTCGGTCGA
GGGAGAGGCCATGATTATCGAGACGGCCAGGGCGGTAAAGGCGGCCGGCGCCCAGGTGCTTCGGGGCGGAGCGTTCAAGC
CGCGCACCTCTCCCTACTCCTTCCAGGGACTCGAAGAGGAAGGGCTCAAGCTGCTGGCCAAGGCGCGCGAGGAGACGGGT
CTCCCCATCGTGACCGAGGTGGTCAATCCCGAGACGGCCGAACTGGTGTCCGAGTACTCCGACATTCTCCAGATCGGAGC
CCGCAATGCCCAGAACTTTGCCCTGCTCAAGAAGGTGGGGCAGCTTCGGCGCCCGGTGCTCCTCAAGCGGGGCATGTCCA
TGACCATCCAGGAGTTCCTCATGAGCGCCGAGTATGTCATGAGTGAAGGGAATCAGTCGGTTATCCTCTGCGAACGCGGT
ATCCGCACCTTCGAGACCGCCACCCGCAACACGCTGGATCTCTCGGCCATTCCGGTGTTGAAGCAGATGACCCATCTGCC
GGTCATTGCCGATCCTTCCCACGGCACCGGAAACTATCACTATGTGGCACCCATGGCCCTGGCAGCTGTTGCCGCCGGCG
CGGACGGGCTCATGATCGAGGTGCATCCCGATCCCGAGCGTGCGTCGTCCGATGGGCCCCAGTCGCTCAAGCCGAAGAAA
TTCGACGCGCTTATGGCAAAGTTGCGGCTCGTGGCGGCGTCCGTGGACAGGCGACTGTAA

Upstream 100 bases:

>100_bases
CCCCCGGCTTTTCAGTTTTCAAGACCAATACTGCAGCACCACTGGGCCGGGGGAGAAATCCTCCGGCCTTTTGTCTTTCG
GGACACCACGGGAGGAAGGG

Downstream 100 bases:

>100_bases
CGATGCGTGGCCGCCTGTCCCATGCCGGGTCGGGAAAGGGCTTGCGGGGGGGCGGGAGATTCGCTATGGTGAGAGCACAT
TAATCCATGGAGGGATTTCA

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIIVMKAGAAKKDRDEVIRRIRELGYKPHVIHGTTRDVIGAVGDERGKLVLQGVESMHGVESVVPILKPYKLASREVKPE
PSVVAITDTVVIGGPEVIVMAGPCSVEGEAMIIETARAVKAAGAQVLRGGAFKPRTSPYSFQGLEEEGLKLLAKAREETG
LPIVTEVVNPETAELVSEYSDILQIGARNAQNFALLKKVGQLRRPVLLKRGMSMTIQEFLMSAEYVMSEGNQSVILCERG
IRTFETATRNTLDLSAIPVLKQMTHLPVIADPSHGTGNYHYVAPMALAAVAAGADGLMIEVHPDPERASSDGPQSLKPKK
FDALMAKLRLVAASVDRRL

Sequences:

>Translated_339_residues
MIIVMKAGAAKKDRDEVIRRIRELGYKPHVIHGTTRDVIGAVGDERGKLVLQGVESMHGVESVVPILKPYKLASREVKPE
PSVVAITDTVVIGGPEVIVMAGPCSVEGEAMIIETARAVKAAGAQVLRGGAFKPRTSPYSFQGLEEEGLKLLAKAREETG
LPIVTEVVNPETAELVSEYSDILQIGARNAQNFALLKKVGQLRRPVLLKRGMSMTIQEFLMSAEYVMSEGNQSVILCERG
IRTFETATRNTLDLSAIPVLKQMTHLPVIADPSHGTGNYHYVAPMALAAVAAGADGLMIEVHPDPERASSDGPQSLKPKK
FDALMAKLRLVAASVDRRL
>Mature_339_residues
MIIVMKAGAAKKDRDEVIRRIRELGYKPHVIHGTTRDVIGAVGDERGKLVLQGVESMHGVESVVPILKPYKLASREVKPE
PSVVAITDTVVIGGPEVIVMAGPCSVEGEAMIIETARAVKAAGAQVLRGGAFKPRTSPYSFQGLEEEGLKLLAKAREETG
LPIVTEVVNPETAELVSEYSDILQIGARNAQNFALLKKVGQLRRPVLLKRGMSMTIQEFLMSAEYVMSEGNQSVILCERG
IRTFETATRNTLDLSAIPVLKQMTHLPVIADPSHGTGNYHYVAPMALAAVAAGADGLMIEVHPDPERASSDGPQSLKPKK
FDALMAKLRLVAASVDRRL

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=208, Percent_Identity=28.3653846153846, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 36588; Mature: 36588

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVMKAGAAKKDRDEVIRRIRELGYKPHVIHGTTRDVIGAVGDERGKLVLQGVESMHGV
CEEEEECCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHH
ESVVPILKPYKLASREVKPEPSVVAITDTVVIGGPEVIVMAGPCSVEGEAMIIETARAVK
HHHHHHHCCHHHHCCCCCCCCCEEEEEEEEEECCCEEEEEECCCCCCCCEEEEHHHHHHH
AAGAQVLRGGAFKPRTSPYSFQGLEEEGLKLLAKAREETGLPIVTEVVNPETAELVSEYS
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
DILQIGARNAQNFALLKKVGQLRRPVLLKRGMSMTIQEFLMSAEYVMSEGNQSVILCERG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
IRTFETATRNTLDLSAIPVLKQMTHLPVIADPSHGTGNYHYVAPMALAAVAAGADGLMIE
CHHHHHHCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCEEEHHHHHHHHHHCCCCCEEEE
VHPDPERASSDGPQSLKPKKFDALMAKLRLVAASVDRRL
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIVMKAGAAKKDRDEVIRRIRELGYKPHVIHGTTRDVIGAVGDERGKLVLQGVESMHGV
CEEEEECCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHH
ESVVPILKPYKLASREVKPEPSVVAITDTVVIGGPEVIVMAGPCSVEGEAMIIETARAVK
HHHHHHHCCHHHHCCCCCCCCCEEEEEEEEEECCCEEEEEECCCCCCCCEEEEHHHHHHH
AAGAQVLRGGAFKPRTSPYSFQGLEEEGLKLLAKAREETGLPIVTEVVNPETAELVSEYS
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
DILQIGARNAQNFALLKKVGQLRRPVLLKRGMSMTIQEFLMSAEYVMSEGNQSVILCERG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
IRTFETATRNTLDLSAIPVLKQMTHLPVIADPSHGTGNYHYVAPMALAAVAAGADGLMIE
CHHHHHHCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCEEEHHHHHHHHHHCCCCCEEEE
VHPDPERASSDGPQSLKPKKFDALMAKLRLVAASVDRRL
ECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]