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The map label for this gene is cobL [H]

Identifier: 39998087

GI number: 39998087

Start: 3289754

End: 3290971

Strand: Reverse

Name: cobL [H]

Synonym: GSU2996

Alternate gene names: 39998087

Gene position: 3290971-3289754 (Counterclockwise)

Preceding gene: 39998088

Following gene: 39998086

Centisome position: 86.28

GC content: 63.55

Gene sequence:

>1218_bases
ATGCCTCATCAGAAAATTTATCTCGTCGGCGCCGGCATCGAAGGGTGGGAGGGGTTCGGCTCCAAGGCCCTCGAAGTCAT
CAACGAGGCCGAGGTTCTCATCGGCCACCGGCGTCATCTGGACACCTTTCCCGAGTTCAAGGGGAAGAAGCAGGAACTGG
GCGATCTCTCCATCCTCCTGGAGCAGCTGAAGAACACCGACAAGCGGACCGTTGTCCTTGGCTCCGGGGACCCCAACTTT
TTCGGCATCGCCCGCTTCCTGCTCCGCAATCTCTCCAAGGACCGGATCGAGATCTTTCCCAACGTGACGAGCGTGCAGTA
CGCCTTTGCCCGGATCAAGGAACCCTGGGACGACGCCATCTTCGTCTCGGTGCACGGCCGGGGGCTCAAGCCCGCCGTGG
ACCGGATCGTGGCCGCCGAGAAGGTGGCGGTTCTTACCGACAAGATCAATACCCCCGCAGCCATCGCCCGCGAACTGATC
GAGCGCGGCGCCGAGGGGTACGAGGCGTGGCTCTGCGAGGACATGGGGACGCCGGCCGAGAAGTTCACCCGCACCGATGT
GAAGGGGCTGCTGGACATTGCCGCCTCGGAACTCAACATCCTCATCCTCGTGAAGGCATGGGAACCCCAGCTGGCCCAGT
ACCCGGTCATGGGCATCGCGGACGACGAGTTCGCCACGGCCAAGAAGCTGATCACCAAGCAGGAAGTGCGGGCCGTCACC
CTGGCCAAGCTCCGGCTCCAGGACGACCTGGTCATGTGGGACATCGGCGCGGGCAGCGGCTCGGTATCCATCGAGGCGTC
CAACCTCATGCCCAATGGCCGGCTCTTCGCCCTGGAGCGCAATCCCCAGTACGTGACCTTCCTGCGGGAGAACCTGAAGA
AATTCGTGGCCCGCAACGTCGTGCTGGTGGAGGCGTTCGCCCCCGAGGGGCTCGATGAGCTGCCCGACCCCGACCGGGTT
TTCATCGGCGGTTCCGGCGGCATGCTGGAGGAGATCATCGAGGCCGTGGACCGCCGGCTCAAGCCCGAGGGGGTCATCGT
CCTCAACGCCGTGACCCTGGATACCCTCACCAAGGCGGTGGAGTTCCTGGAAGACCACGGCTACCTGGTGGAGGTGGCGT
GCGTCAACGTGGCCAAGACCCGAGGGCTCACCGAGTACAAGATGTTCGAGGCCCAGAATCCGGTCTACATCATCTCGGCA
TGGAAAGGCGAAGAGTGA

Upstream 100 bases:

>100_bases
TGCGCATCAAGGTTTTGCTGGCGGGCTACGATTCAACGGTGCTATATTTCGGATAAAATGTTCGCTCTGTCCTGCAATTT
GCCATAAAGGAGGTTTCCCC

Downstream 100 bases:

>100_bases
GCGGTTTCGCCAAAATTTACGCCGTCGGGGTCGGCCCCGGCGACCCGGAACTCCTGACCCGGAAGGCCGAGCGGATCATC
CGCTCGGCCGATGTCATCTG

Product: precorrin-6y c5,15-methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MPHQKIYLVGAGIEGWEGFGSKALEVINEAEVLIGHRRHLDTFPEFKGKKQELGDLSILLEQLKNTDKRTVVLGSGDPNF
FGIARFLLRNLSKDRIEIFPNVTSVQYAFARIKEPWDDAIFVSVHGRGLKPAVDRIVAAEKVAVLTDKINTPAAIARELI
ERGAEGYEAWLCEDMGTPAEKFTRTDVKGLLDIAASELNILILVKAWEPQLAQYPVMGIADDEFATAKKLITKQEVRAVT
LAKLRLQDDLVMWDIGAGSGSVSIEASNLMPNGRLFALERNPQYVTFLRENLKKFVARNVVLVEAFAPEGLDELPDPDRV
FIGGSGGMLEEIIEAVDRRLKPEGVIVLNAVTLDTLTKAVEFLEDHGYLVEVACVNVAKTRGLTEYKMFEAQNPVYIISA
WKGEE

Sequences:

>Translated_405_residues
MPHQKIYLVGAGIEGWEGFGSKALEVINEAEVLIGHRRHLDTFPEFKGKKQELGDLSILLEQLKNTDKRTVVLGSGDPNF
FGIARFLLRNLSKDRIEIFPNVTSVQYAFARIKEPWDDAIFVSVHGRGLKPAVDRIVAAEKVAVLTDKINTPAAIARELI
ERGAEGYEAWLCEDMGTPAEKFTRTDVKGLLDIAASELNILILVKAWEPQLAQYPVMGIADDEFATAKKLITKQEVRAVT
LAKLRLQDDLVMWDIGAGSGSVSIEASNLMPNGRLFALERNPQYVTFLRENLKKFVARNVVLVEAFAPEGLDELPDPDRV
FIGGSGGMLEEIIEAVDRRLKPEGVIVLNAVTLDTLTKAVEFLEDHGYLVEVACVNVAKTRGLTEYKMFEAQNPVYIISA
WKGEE
>Mature_404_residues
PHQKIYLVGAGIEGWEGFGSKALEVINEAEVLIGHRRHLDTFPEFKGKKQELGDLSILLEQLKNTDKRTVVLGSGDPNFF
GIARFLLRNLSKDRIEIFPNVTSVQYAFARIKEPWDDAIFVSVHGRGLKPAVDRIVAAEKVAVLTDKINTPAAIARELIE
RGAEGYEAWLCEDMGTPAEKFTRTDVKGLLDIAASELNILILVKAWEPQLAQYPVMGIADDEFATAKKLITKQEVRAVTL
AKLRLQDDLVMWDIGAGSGSVSIEASNLMPNGRLFALERNPQYVTFLRENLKKFVARNVVLVEAFAPEGLDELPDPDRVF
IGGSGGMLEEIIEAVDRRLKPEGVIVLNAVTLDTLTKAVEFLEDHGYLVEVACVNVAKTRGLTEYKMFEAQNPVYIISAW
KGEE

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 44962; Mature: 44831

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHQKIYLVGAGIEGWEGFGSKALEVINEAEVLIGHRRHLDTFPEFKGKKQELGDLSILL
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHH
EQLKNTDKRTVVLGSGDPNFFGIARFLLRNLSKDRIEIFPNVTSVQYAFARIKEPWDDAI
HHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCCCCCEE
FVSVHGRGLKPAVDRIVAAEKVAVLTDKINTPAAIARELIERGAEGYEAWLCEDMGTPAE
EEEECCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCHH
KFTRTDVKGLLDIAASELNILILVKAWEPQLAQYPVMGIADDEFATAKKLITKQEVRAVT
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHCCCCEECCCCHHHHHHHHHHHHHHHHHH
LAKLRLQDDLVMWDIGAGSGSVSIEASNLMPNGRLFALERNPQYVTFLRENLKKFVARNV
HHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCE
VLVEAFAPEGLDELPDPDRVFIGGSGGMLEEIIEAVDRRLKPEGVIVLNAVTLDTLTKAV
EEEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHH
EFLEDHGYLVEVACVNVAKTRGLTEYKMFEAQNPVYIISAWKGEE
HHHHCCCCEEEEEEEHHHHHCCCCHHHHCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
PHQKIYLVGAGIEGWEGFGSKALEVINEAEVLIGHRRHLDTFPEFKGKKQELGDLSILL
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHHH
EQLKNTDKRTVVLGSGDPNFFGIARFLLRNLSKDRIEIFPNVTSVQYAFARIKEPWDDAI
HHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHCCCCCCEE
FVSVHGRGLKPAVDRIVAAEKVAVLTDKINTPAAIARELIERGAEGYEAWLCEDMGTPAE
EEEECCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCHH
KFTRTDVKGLLDIAASELNILILVKAWEPQLAQYPVMGIADDEFATAKKLITKQEVRAVT
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHCCCCEECCCCHHHHHHHHHHHHHHHHHH
LAKLRLQDDLVMWDIGAGSGSVSIEASNLMPNGRLFALERNPQYVTFLRENLKKFVARNV
HHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCE
VLVEAFAPEGLDELPDPDRVFIGGSGGMLEEIIEAVDRRLKPEGVIVLNAVTLDTLTKAV
EEEEECCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHH
EFLEDHGYLVEVACVNVAKTRGLTEYKMFEAQNPVYIISAWKGEE
HHHHCCCCEEEEEEEHHHHHCCCCHHHHCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]