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The map label for this gene is tsr [C]

Identifier: 39998033

GI number: 39998033

Start: 3238978

End: 3240612

Strand: Direct

Name: tsr [C]

Synonym: GSU2942

Alternate gene names: 39998033

Gene position: 3238978-3240612 (Clockwise)

Preceding gene: 39998032

Following gene: 39998034

Centisome position: 84.92

GC content: 62.45

Gene sequence:

>1635_bases
ATGCGCGTTATCAGGAACTTGCATCTGAGCACAAAACTGGTGGCGGGTTTCGTACTCGTGGCCGTTATAGCAGGATTGGT
CGGCCTCATCGGCACCCTGAAGATCCGCGTCATGGAAACGGCCGGCACTGAAATGTACGATCTGGTTACCGAACCCCTCG
GCACCATGGGCGGAGTGGCCATCGCCTTCCAGAAGGCACGGGTCAACATTCGCGGCATGATCCTTGACGACAATCCCGCC
CGAGCCCAGGCCAACGCAAACTCCATCGCCAAGTTCTACAAGGAGATCGACGAAGGGCTGGCGGATTTCGGCAAGAGCAT
CCTCAGCAAAGATATCCGGCAGGAATTCGACGCCCTCAGAAACACCATCGCTGAGTATGCACCGGTGCGGGAAGAAATCG
TCACCGCGACCCTTGACGGAGACCGGGAAACAGCGCTGGCTCTCATGCGGAGCCAGGGGCTGGCCTTCGAAAAGAAGATC
GATGAATCGATCAAGAAGCTCTTCGACATGAAGATCGCCGGGGCGAAAAAGCGAAAAGACATGAATGCGGCAGCGGCACA
AAGCGCACTGACCCAGATGATGCTTCTTGCCCTCATCGGCATGGTTGTCGCCGTGGTCCTCGGCCTCTTTGTCTCTCGCC
AGATCACGGTACCGCTCAGGAAGGTCGTAGACTTTGCCCAGGCCATCGCCCAGGGCGACCTGGCTCACCGCCTGGATATG
GAACAGAATGACGAGACCGGGCAACTGGCCGAGGCCGTCAACACCATGGCGGATCGGCTCAACCGGCTCATTGCCGGCGT
GGCCGAAAATGCATCCCAGGTGGCGGCGGCGGCGAGCCAGCTCACCTCCAATGCAGAGCAAATGGCGACCGGCGCGGAGG
AGGTGGCGGCACAAACCGGTACCGTGGCCACGGCCAGCGAGGAAATGGCGTCCACCTCGGCGGAGATCGCCCAGAACTGC
ACCGCCGCTGCTGAAGAGTCCCGACGGGCAAGCGATACGGCGGTCCAGGGTTCGGAGGTCATTCGCCATACGGTCGGCGA
GATGGAGCGAATCGCCGAGCGGGTCCGCGAGACGGCCAGAACCGTGGAAAGTCTCGGGGCCCGGAGTGATCAGATCGGTG
AAATCATCGGCACCATTGAGGATATCGCCGACCAGACGAACCTTCTGGCCCTGAACGCGGCCATCGAGGCGGCCCGGGCC
GGTGAACAGGGGCGCGGCTTCGCCGTGGTCGCCGACGAGGTCCGGGCACTGGCGGAGCGGACATCCCGCGCTACCAGGGA
AATCAGTACCATGATCAAGGCGATCCAGCAGGAGACCAAGGGGGCCGTCGCCTCCATGGAGCAGGGGGTGCGGGAAGTGG
AACGCGGCACGGCCGAGGCATCCCAGTCGGGCAAGGCCTTGGAAGAGATCCTGGAGCAGGTGGGCTGTGTGACCATGCAG
ATCAACCAGATAGCAACGGCAGCCGAGCAGCAGACCTCGACCACGTCGGAGATCAGCGGCAACATCCAGCAGATTACCGA
TGTGGTTCAGCAGACGGCCCGGGGTGCCCAGGAAACCGCGGCGGCCGCGCGGCAACTCTCGCAGCTGTCGGCAGAGCTGC
AGCACCTGATCGGCCAGTTCCATCTCGCAGCCTGA

Upstream 100 bases:

>100_bases
TACGCAACAACAGATAACCACACGCGACGTGTGTTCACGATCAAGGATCCGGCCAACGCCGAGCCATCCGATTGGGCTGG
ACCGAAAGGAGAGGAGAACG

Downstream 100 bases:

>100_bases
CCGTCTTCATCTGTTAACGAAAAAAGGACCCTCCGATCCGGGGGGTCCTTTTTTCGTTACGTGACGCAGGCAGGGAACGC
TATCGGGCGAGTACATTTTT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MRVIRNLHLSTKLVAGFVLVAVIAGLVGLIGTLKIRVMETAGTEMYDLVTEPLGTMGGVAIAFQKARVNIRGMILDDNPA
RAQANANSIAKFYKEIDEGLADFGKSILSKDIRQEFDALRNTIAEYAPVREEIVTATLDGDRETALALMRSQGLAFEKKI
DESIKKLFDMKIAGAKKRKDMNAAAAQSALTQMMLLALIGMVVAVVLGLFVSRQITVPLRKVVDFAQAIAQGDLAHRLDM
EQNDETGQLAEAVNTMADRLNRLIAGVAENASQVAAAASQLTSNAEQMATGAEEVAAQTGTVATASEEMASTSAEIAQNC
TAAAEESRRASDTAVQGSEVIRHTVGEMERIAERVRETARTVESLGARSDQIGEIIGTIEDIADQTNLLALNAAIEAARA
GEQGRGFAVVADEVRALAERTSRATREISTMIKAIQQETKGAVASMEQGVREVERGTAEASQSGKALEEILEQVGCVTMQ
INQIATAAEQQTSTTSEISGNIQQITDVVQQTARGAQETAAAARQLSQLSAELQHLIGQFHLAA

Sequences:

>Translated_544_residues
MRVIRNLHLSTKLVAGFVLVAVIAGLVGLIGTLKIRVMETAGTEMYDLVTEPLGTMGGVAIAFQKARVNIRGMILDDNPA
RAQANANSIAKFYKEIDEGLADFGKSILSKDIRQEFDALRNTIAEYAPVREEIVTATLDGDRETALALMRSQGLAFEKKI
DESIKKLFDMKIAGAKKRKDMNAAAAQSALTQMMLLALIGMVVAVVLGLFVSRQITVPLRKVVDFAQAIAQGDLAHRLDM
EQNDETGQLAEAVNTMADRLNRLIAGVAENASQVAAAASQLTSNAEQMATGAEEVAAQTGTVATASEEMASTSAEIAQNC
TAAAEESRRASDTAVQGSEVIRHTVGEMERIAERVRETARTVESLGARSDQIGEIIGTIEDIADQTNLLALNAAIEAARA
GEQGRGFAVVADEVRALAERTSRATREISTMIKAIQQETKGAVASMEQGVREVERGTAEASQSGKALEEILEQVGCVTMQ
INQIATAAEQQTSTTSEISGNIQQITDVVQQTARGAQETAAAARQLSQLSAELQHLIGQFHLAA
>Mature_544_residues
MRVIRNLHLSTKLVAGFVLVAVIAGLVGLIGTLKIRVMETAGTEMYDLVTEPLGTMGGVAIAFQKARVNIRGMILDDNPA
RAQANANSIAKFYKEIDEGLADFGKSILSKDIRQEFDALRNTIAEYAPVREEIVTATLDGDRETALALMRSQGLAFEKKI
DESIKKLFDMKIAGAKKRKDMNAAAAQSALTQMMLLALIGMVVAVVLGLFVSRQITVPLRKVVDFAQAIAQGDLAHRLDM
EQNDETGQLAEAVNTMADRLNRLIAGVAENASQVAAAASQLTSNAEQMATGAEEVAAQTGTVATASEEMASTSAEIAQNC
TAAAEESRRASDTAVQGSEVIRHTVGEMERIAERVRETARTVESLGARSDQIGEIIGTIEDIADQTNLLALNAAIEAARA
GEQGRGFAVVADEVRALAERTSRATREISTMIKAIQQETKGAVASMEQGVREVERGTAEASQSGKALEEILEQVGCVTMQ
INQIATAAEQQTSTTSEISGNIQQITDVVQQTARGAQETAAAARQLSQLSAELQHLIGQFHLAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=529, Percent_Identity=27.5992438563327, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1788195, Length=341, Percent_Identity=34.3108504398827, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1787690, Length=351, Percent_Identity=30.7692307692308, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI1788194, Length=368, Percent_Identity=29.3478260869565, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789453, Length=346, Percent_Identity=31.7919075144509, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57978; Mature: 57978

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIRNLHLSTKLVAGFVLVAVIAGLVGLIGTLKIRVMETAGTEMYDLVTEPLGTMGGVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHCCCHHHHHHHHHHHHHCCHH
IAFQKARVNIRGMILDDNPARAQANANSIAKFYKEIDEGLADFGKSILSKDIRQEFDALR
HHHHHHCEEEEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTIAEYAPVREEIVTATLDGDRETALALMRSQGLAFEKKIDESIKKLFDMKIAGAKKRKD
HHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
MNAAAAQSALTQMMLLALIGMVVAVVLGLFVSRQITVPLRKVVDFAQAIAQGDLAHRLDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHCCC
EQNDETGQLAEAVNTMADRLNRLIAGVAENASQVAAAASQLTSNAEQMATGAEEVAAQTG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHCC
TVATASEEMASTSAEIAQNCTAAAEESRRASDTAVQGSEVIRHTVGEMERIAERVRETAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVESLGARSDQIGEIIGTIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAER
HHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHH
TSRATREISTMIKAIQQETKGAVASMEQGVREVERGTAEASQSGKALEEILEQVGCVTMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHH
INQIATAAEQQTSTTSEISGNIQQITDVVQQTARGAQETAAAARQLSQLSAELQHLIGQF
HHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
HLAA
HCCC
>Mature Secondary Structure
MRVIRNLHLSTKLVAGFVLVAVIAGLVGLIGTLKIRVMETAGTEMYDLVTEPLGTMGGVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHCCCHHHHHHHHHHHHHCCHH
IAFQKARVNIRGMILDDNPARAQANANSIAKFYKEIDEGLADFGKSILSKDIRQEFDALR
HHHHHHCEEEEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTIAEYAPVREEIVTATLDGDRETALALMRSQGLAFEKKIDESIKKLFDMKIAGAKKRKD
HHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
MNAAAAQSALTQMMLLALIGMVVAVVLGLFVSRQITVPLRKVVDFAQAIAQGDLAHRLDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHCCC
EQNDETGQLAEAVNTMADRLNRLIAGVAENASQVAAAASQLTSNAEQMATGAEEVAAQTG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHCC
TVATASEEMASTSAEIAQNCTAAAEESRRASDTAVQGSEVIRHTVGEMERIAERVRETAR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVESLGARSDQIGEIIGTIEDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAER
HHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHH
TSRATREISTMIKAIQQETKGAVASMEQGVREVERGTAEASQSGKALEEILEQVGCVTMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHH
INQIATAAEQQTSTTSEISGNIQQITDVVQQTARGAQETAAAARQLSQLSAELQHLIGQF
HHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
HLAA
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA