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The map label for this gene is pyc [H]

Identifier: 39997523

GI number: 39997523

Start: 2660074

End: 2663520

Strand: Reverse

Name: pyc [H]

Synonym: GSU2428

Alternate gene names: 39997523

Gene position: 2663520-2660074 (Counterclockwise)

Preceding gene: 39997525

Following gene: 39997522

Centisome position: 69.83

GC content: 64.03

Gene sequence:

>3447_bases
ATGGAAAAGAGAAAGTTCAGAAAAGTAATGGCCGCCAACCGCGGAGAGATCGCGATCCGCATCTTCCGGGCCTGCACTGA
GCTGGGGATCAGCACGGTGGCCATCTACTCGGAGGAGGACAAGCTGTCCCTCCACCGCTACAAGGCGGACGAGGCCTACC
TGGTGGGCAAGGGGAAAGCCCCCATCGATGCCTACCTGGGGATCGACGAAATCATCTCCATTGCCAAGCGGGCGGACGTG
GACGCCATTCACCCGGGCTACGGCTTCCTTTCGGAGAATGCCGAGTTCGCCGAGGCGTGCGAGCGGGCCGGCATCGCCTT
CATCGGTCCCCGGGCCGAGATGCAGCGGGCCCTGGGCGACAAGGTCTCGGCCCGCAAGGTGGCCATTGCCGCCGAGGTGC
CCGTGGTTCCCGGAACCGAGGAGCCCATCGAGCACGAGGAAGAAGCGCTCATCTTCGCCAAGCAGCACGGCTATCCCATC
ATCATCAAGGCGGCTGCCGGCGGCGGCGGGCGGGGCATGCGGGTTGCCCGCAACAAGAAAGAGCTGCTGGAGGGGCTGGT
GGCGGCCCGCAGCGAGGCCAAGGCCGCCTTCGGCAACCCGGCGGTCTTCCTGGAGCGCTACCTGGAGAATCCCAAGCACA
TCGAGGTGCAGGTGCTGGGGGACCACCACGGCAACCTGGTCCACTTCTACGAGCGCGACTGCTCCATCCAGCGCCGTCAC
CAGAAGGTGGTTGAGTTCGCGCCGTCGCTCTCCCTGACCCAGAAGCTGCGGGACGAGATCTGCAACGCGGCCCTCAAGAT
CGCGGGTCAGGTGGGCTACGTGAACGCCGGCACCGTGGAATTCCTGCTGGACCAGGAGGGGAGCTGGTACTTCATCGAGA
TGAACCCCCGAATCCAGGTGGAGCACACGGTCACCGAGATGATCACCGGCAGGAACCTGGTGCAGGCCCAGATCCTCATC
GCCGAGGGGAAGAAGCTCTCGGACCCCCCCATCAACGTCCCGAACCAGTCGGCCATCGCCATGCGGGGCTACGCCATCCA
GTGCCGGATCACCACCGAGGACCCGGCCAACAACTTTGCCCCGGATTTCGGCACCATCACCACCTACCGCTCCTCGGCCG
GCTTCGGGGTGCGGCTCGACGCGGGCAACGCCTTCACCGGTTCGGTCATCACCCCCCATTACGACTCGCTTCTGGTGAAG
GTCACCTCGTGGGGGCTCACCTTCGACGAGGCGGCCCACATCATGAACCGCTCCCTCCAGGAGTTCCGGGTCCGGGGCGT
GAAGACCAATATCCCGTTCCTGGAGAACGTGGTCACCCACCCGGTCTTCCTGGCCGGTACCTGCGATACGTCATTCATCG
AGAAGCACCCCGAGCTTCTGGCCATTAGCGAGAAGAAAGACCGGGCCACCAAGGTGCTCAATTTCCTGGGCGACGTCATC
GTGAACGGCTCCCCCGGCGTTGCCAAGCCCCTCAAGTCGGCGGAGATGATCGAGGCCCGGGTGCCCGAGGTTGACTATAC
GGTTCCCCGGCCCGCCGGCTCCCGCGACCTGTTCATGAAGCTCGGCGCCGAGGGGCTCTCCAAGTGGATCCTGGAGCAGA
AAAAGCTCCTGATCACCGACACCACCATGCGGGATGCCCACCAGTCGCTCCTGGCGACCCGGGTCCGCACCTATGACCTG
CTAAAGATCGCCGAGCCCACCTCGTACCTGGGTGCCGGGCTCTTCTCGCTGGAGTGCTGGGGCGGCGCCACCTTCGACGT
CTCCATGCGCTTCCTGAAGGAGGATCCCTGGCAGCGGCTCCACAAGCTCTCGGAGGCGATCCCCAACATCCTCTTCCAGA
TGCTCCTGCGGGGCTCCAACGCCGTGGGCTACACCAACTATCCCGACAACGTGGTGCAGCGCTTCGTGGAGGAGGCCGCC
GCCAGCGGCGTCGACATCTTCCGGGTCTTCGATTCCCTCAACTGGACCCGGGGGATGACCGTGGCCATGGAGGCGGTGCG
CAAGACCGGCAAGATCTGCGAGGCGGCCATCTGCTACACCGGCGACATCACCGATCCCAAGCGGGACAAGTATCCGCTGG
AATACTACGTGGCCATGGCCAAGGAACTGGAGCAGATGGGCGCCCACATCCTGGCCATCAAGGACATGGCGGGGCTGCTC
AAGCCCATGGCCGCCCACAAGCTGGTGAAGGCCCTCAAGGAGAACATCGGCATCCCGGTCCACCTCCATACCCACGATAC
CTCCTCCAACGGCAACGCCACGCTGCTCATGGCCTGCCAGGCCGGGGTCGACATCGTGGACGCGGCCCTCTCCTCCATCT
CCGGCCTCACGGCCCAGCCGAACCTGAACGCGCTCCTGGCCGCCCTCAAGGGGACCGAGTGGGACCCGGCCCTGGACGAC
GAGGGGCTCCAGCACCTGGCCAACTACTGGGAGACGGTGCGGGACTACTACACCCCCTTCGAATCGGGGCTCAAGAGCGG
CACTGCCGAGGTCTACCACCACGAGATCCCCGGCGGCCAGTACTCCAACTACAAGCCCCAGGTGGCCGGTCTCGGCCTGC
TGGACCGGTGGGAGGAGTGCAAGGAGATGTACTTCAAGGTCAACAGGCTCTTTGGCGACATCGTCAAGGTGACCCCCTCC
TCCAAGGTGGTGGGCGACATGGCCATGTTCCTGGTGAAAAACAACCTGGACGTGGACGACGTCTTCACCAAGGGGGACGA
GCTCAGCTTCCCCGAGTCGGTAGTGGGGATGTTCAAGGGGATGCTGGGCCAGCCCTACCAGGGGTGGCCCGCTGAGCTGC
AGAAGATCATCCTCAAGGGAGAAGAGCCGATCACCTGCCGCCCCGGCGAGCTCCTGGAGCCGGCCGACTTCGAAGAGAAG
CGCCTGGAGGCCGAGACCAAGGTGGGGCACGCGGTGAACGACAAGGATCTCATGTCGTACCTGCTCTACCCTCATGTCTA
CCCCGAGTTCGACAAGCACCGTCAGGAGTATTCGGACACCTCGGTCATCCCGACCCCCATCTTCTTCTACGGCCTGGAGC
CGGGGCAGGAGACCTCCATCGACATCGAGCCGGGCAAGACCCTCATCATCAAGCTCAACGCCGTCGGCAAGGTGCATCCG
GACGGTACCCGCCACATCTTCTTCGAGCTTAACGGCCAACAGCGGCAGGTGGTGGTGCGCGACCAATCGGTGCAGACCGA
CGAGGCCGAGCGGGAAAAGGCCGACAAGGGGAACGCCAAGCATATCGGCGCGCCCATGCCCGGCAAGGTCCTGAAGCTCA
ATGTGAAGGCGGGCGACGTCGTGAAGGCGGGAGACGTCCTCATGGTTACCGAGGCCATGAAGATGGAGACCAACATCAAG
GCGAAAGAAGACGGCGCCGTTGCCGAGGTGAAGTTCAAGGAAGGCGACAAGGTGGAAAAAGAAGATCTGGTGATCGTGAT
GGCATAG

Upstream 100 bases:

>100_bases
AGTCGTGTAACTATATAAAATAACGAAATAATTTTAGTTTAACTAAAGTTTTAATTAGGTTGTATTTGTTTTATTTTAGG
TAAAAACCGGGGAGGTTCCG

Downstream 100 bases:

>100_bases
CGAATCGTAGCGAAAAACACTCGAAACCGTCACGGGAACGTGGTATTAAAGGGGGGCCGCCAATGAGGCGGCTCCCCTTT
TTTCGATGACGGTGCCGGAT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1148; Mature: 1148

Protein sequence:

>1148_residues
MEKRKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKAPIDAYLGIDEIISIAKRADV
DAIHPGYGFLSENAEFAEACERAGIAFIGPRAEMQRALGDKVSARKVAIAAEVPVVPGTEEPIEHEEEALIFAKQHGYPI
IIKAAAGGGGRGMRVARNKKELLEGLVAARSEAKAAFGNPAVFLERYLENPKHIEVQVLGDHHGNLVHFYERDCSIQRRH
QKVVEFAPSLSLTQKLRDEICNAALKIAGQVGYVNAGTVEFLLDQEGSWYFIEMNPRIQVEHTVTEMITGRNLVQAQILI
AEGKKLSDPPINVPNQSAIAMRGYAIQCRITTEDPANNFAPDFGTITTYRSSAGFGVRLDAGNAFTGSVITPHYDSLLVK
VTSWGLTFDEAAHIMNRSLQEFRVRGVKTNIPFLENVVTHPVFLAGTCDTSFIEKHPELLAISEKKDRATKVLNFLGDVI
VNGSPGVAKPLKSAEMIEARVPEVDYTVPRPAGSRDLFMKLGAEGLSKWILEQKKLLITDTTMRDAHQSLLATRVRTYDL
LKIAEPTSYLGAGLFSLECWGGATFDVSMRFLKEDPWQRLHKLSEAIPNILFQMLLRGSNAVGYTNYPDNVVQRFVEEAA
ASGVDIFRVFDSLNWTRGMTVAMEAVRKTGKICEAAICYTGDITDPKRDKYPLEYYVAMAKELEQMGAHILAIKDMAGLL
KPMAAHKLVKALKENIGIPVHLHTHDTSSNGNATLLMACQAGVDIVDAALSSISGLTAQPNLNALLAALKGTEWDPALDD
EGLQHLANYWETVRDYYTPFESGLKSGTAEVYHHEIPGGQYSNYKPQVAGLGLLDRWEECKEMYFKVNRLFGDIVKVTPS
SKVVGDMAMFLVKNNLDVDDVFTKGDELSFPESVVGMFKGMLGQPYQGWPAELQKIILKGEEPITCRPGELLEPADFEEK
RLEAETKVGHAVNDKDLMSYLLYPHVYPEFDKHRQEYSDTSVIPTPIFFYGLEPGQETSIDIEPGKTLIIKLNAVGKVHP
DGTRHIFFELNGQQRQVVVRDQSVQTDEAEREKADKGNAKHIGAPMPGKVLKLNVKAGDVVKAGDVLMVTEAMKMETNIK
AKEDGAVAEVKFKEGDKVEKEDLVIVMA

Sequences:

>Translated_1148_residues
MEKRKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKAPIDAYLGIDEIISIAKRADV
DAIHPGYGFLSENAEFAEACERAGIAFIGPRAEMQRALGDKVSARKVAIAAEVPVVPGTEEPIEHEEEALIFAKQHGYPI
IIKAAAGGGGRGMRVARNKKELLEGLVAARSEAKAAFGNPAVFLERYLENPKHIEVQVLGDHHGNLVHFYERDCSIQRRH
QKVVEFAPSLSLTQKLRDEICNAALKIAGQVGYVNAGTVEFLLDQEGSWYFIEMNPRIQVEHTVTEMITGRNLVQAQILI
AEGKKLSDPPINVPNQSAIAMRGYAIQCRITTEDPANNFAPDFGTITTYRSSAGFGVRLDAGNAFTGSVITPHYDSLLVK
VTSWGLTFDEAAHIMNRSLQEFRVRGVKTNIPFLENVVTHPVFLAGTCDTSFIEKHPELLAISEKKDRATKVLNFLGDVI
VNGSPGVAKPLKSAEMIEARVPEVDYTVPRPAGSRDLFMKLGAEGLSKWILEQKKLLITDTTMRDAHQSLLATRVRTYDL
LKIAEPTSYLGAGLFSLECWGGATFDVSMRFLKEDPWQRLHKLSEAIPNILFQMLLRGSNAVGYTNYPDNVVQRFVEEAA
ASGVDIFRVFDSLNWTRGMTVAMEAVRKTGKICEAAICYTGDITDPKRDKYPLEYYVAMAKELEQMGAHILAIKDMAGLL
KPMAAHKLVKALKENIGIPVHLHTHDTSSNGNATLLMACQAGVDIVDAALSSISGLTAQPNLNALLAALKGTEWDPALDD
EGLQHLANYWETVRDYYTPFESGLKSGTAEVYHHEIPGGQYSNYKPQVAGLGLLDRWEECKEMYFKVNRLFGDIVKVTPS
SKVVGDMAMFLVKNNLDVDDVFTKGDELSFPESVVGMFKGMLGQPYQGWPAELQKIILKGEEPITCRPGELLEPADFEEK
RLEAETKVGHAVNDKDLMSYLLYPHVYPEFDKHRQEYSDTSVIPTPIFFYGLEPGQETSIDIEPGKTLIIKLNAVGKVHP
DGTRHIFFELNGQQRQVVVRDQSVQTDEAEREKADKGNAKHIGAPMPGKVLKLNVKAGDVVKAGDVLMVTEAMKMETNIK
AKEDGAVAEVKFKEGDKVEKEDLVIVMA
>Mature_1148_residues
MEKRKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKAPIDAYLGIDEIISIAKRADV
DAIHPGYGFLSENAEFAEACERAGIAFIGPRAEMQRALGDKVSARKVAIAAEVPVVPGTEEPIEHEEEALIFAKQHGYPI
IIKAAAGGGGRGMRVARNKKELLEGLVAARSEAKAAFGNPAVFLERYLENPKHIEVQVLGDHHGNLVHFYERDCSIQRRH
QKVVEFAPSLSLTQKLRDEICNAALKIAGQVGYVNAGTVEFLLDQEGSWYFIEMNPRIQVEHTVTEMITGRNLVQAQILI
AEGKKLSDPPINVPNQSAIAMRGYAIQCRITTEDPANNFAPDFGTITTYRSSAGFGVRLDAGNAFTGSVITPHYDSLLVK
VTSWGLTFDEAAHIMNRSLQEFRVRGVKTNIPFLENVVTHPVFLAGTCDTSFIEKHPELLAISEKKDRATKVLNFLGDVI
VNGSPGVAKPLKSAEMIEARVPEVDYTVPRPAGSRDLFMKLGAEGLSKWILEQKKLLITDTTMRDAHQSLLATRVRTYDL
LKIAEPTSYLGAGLFSLECWGGATFDVSMRFLKEDPWQRLHKLSEAIPNILFQMLLRGSNAVGYTNYPDNVVQRFVEEAA
ASGVDIFRVFDSLNWTRGMTVAMEAVRKTGKICEAAICYTGDITDPKRDKYPLEYYVAMAKELEQMGAHILAIKDMAGLL
KPMAAHKLVKALKENIGIPVHLHTHDTSSNGNATLLMACQAGVDIVDAALSSISGLTAQPNLNALLAALKGTEWDPALDD
EGLQHLANYWETVRDYYTPFESGLKSGTAEVYHHEIPGGQYSNYKPQVAGLGLLDRWEECKEMYFKVNRLFGDIVKVTPS
SKVVGDMAMFLVKNNLDVDDVFTKGDELSFPESVVGMFKGMLGQPYQGWPAELQKIILKGEEPITCRPGELLEPADFEEK
RLEAETKVGHAVNDKDLMSYLLYPHVYPEFDKHRQEYSDTSVIPTPIFFYGLEPGQETSIDIEPGKTLIIKLNAVGKVHP
DGTRHIFFELNGQQRQVVVRDQSVQTDEAEREKADKGNAKHIGAPMPGKVLKLNVKAGDVVKAGDVLMVTEAMKMETNIK
AKEDGAVAEVKFKEGDKVEKEDLVIVMA

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1149, Percent_Identity=51.4360313315927, Blast_Score=1136, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1149, Percent_Identity=51.4360313315927, Blast_Score=1136, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1149, Percent_Identity=51.4360313315927, Blast_Score=1136, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=463, Percent_Identity=43.8444924406048, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI65506442, Length=454, Percent_Identity=42.9515418502203, Blast_Score=357, Evalue=5e-98,
Organism=Homo sapiens, GI189095269, Length=453, Percent_Identity=43.046357615894, Blast_Score=356, Evalue=6e-98,
Organism=Homo sapiens, GI295821183, Length=454, Percent_Identity=42.9515418502203, Blast_Score=356, Evalue=8e-98,
Organism=Homo sapiens, GI38679960, Length=507, Percent_Identity=32.3471400394477, Blast_Score=242, Evalue=1e-63,
Organism=Homo sapiens, GI38679974, Length=507, Percent_Identity=32.3471400394477, Blast_Score=242, Evalue=2e-63,
Organism=Homo sapiens, GI38679971, Length=507, Percent_Identity=32.3471400394477, Blast_Score=242, Evalue=2e-63,
Organism=Homo sapiens, GI38679977, Length=507, Percent_Identity=32.3471400394477, Blast_Score=242, Evalue=2e-63,
Organism=Homo sapiens, GI38679967, Length=507, Percent_Identity=32.3471400394477, Blast_Score=242, Evalue=2e-63,
Organism=Homo sapiens, GI134142062, Length=508, Percent_Identity=33.6614173228346, Blast_Score=241, Evalue=3e-63,
Organism=Escherichia coli, GI1789654, Length=459, Percent_Identity=47.4945533769063, Blast_Score=375, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17562816, Length=1149, Percent_Identity=52.5674499564839, Blast_Score=1191, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=463, Percent_Identity=44.7084233261339, Blast_Score=374, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17567343, Length=458, Percent_Identity=42.1397379912664, Blast_Score=344, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI71997168, Length=442, Percent_Identity=31.447963800905, Blast_Score=204, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI71997163, Length=442, Percent_Identity=31.447963800905, Blast_Score=204, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI133931226, Length=495, Percent_Identity=29.8989898989899, Blast_Score=200, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1156, Percent_Identity=50.0865051903114, Blast_Score=1117, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1176, Percent_Identity=50.1700680272109, Blast_Score=1110, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=452, Percent_Identity=38.716814159292, Blast_Score=312, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6324343, Length=529, Percent_Identity=31.1909262759924, Blast_Score=223, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6323863, Length=449, Percent_Identity=33.630289532294, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24652212, Length=1153, Percent_Identity=51.6912402428447, Blast_Score=1164, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1153, Percent_Identity=51.6912402428447, Blast_Score=1164, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1153, Percent_Identity=51.6912402428447, Blast_Score=1164, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1153, Percent_Identity=51.6912402428447, Blast_Score=1164, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1153, Percent_Identity=51.6912402428447, Blast_Score=1164, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1170, Percent_Identity=51.1111111111111, Blast_Score=1153, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1170, Percent_Identity=51.1111111111111, Blast_Score=1153, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1170, Percent_Identity=51.1111111111111, Blast_Score=1153, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1170, Percent_Identity=51.1111111111111, Blast_Score=1153, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1170, Percent_Identity=51.1111111111111, Blast_Score=1153, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=500, Percent_Identity=41.6, Blast_Score=378, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24651759, Length=460, Percent_Identity=41.304347826087, Blast_Score=339, Evalue=6e-93,
Organism=Drosophila melanogaster, GI24586458, Length=524, Percent_Identity=31.6793893129771, Blast_Score=233, Evalue=4e-61,
Organism=Drosophila melanogaster, GI161076409, Length=524, Percent_Identity=31.6793893129771, Blast_Score=233, Evalue=4e-61,
Organism=Drosophila melanogaster, GI161076407, Length=524, Percent_Identity=31.6793893129771, Blast_Score=233, Evalue=5e-61,
Organism=Drosophila melanogaster, GI24586460, Length=524, Percent_Identity=31.6793893129771, Blast_Score=233, Evalue=5e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 126956; Mature: 126956

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKA
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCEEEEECCCC
PIDAYLGIDEIISIAKRADVDAIHPGYGFLSENAEFAEACERAGIAFIGPRAEMQRALGD
CHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECCHHHHHHHHCC
KVSARKVAIAAEVPVVPGTEEPIEHEEEALIFAKQHGYPIIIKAAAGGGGRGMRVARNKK
CCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCHHHCCHH
ELLEGLVAARSEAKAAFGNPAVFLERYLENPKHIEVQVLGDHHGNLVHFYERDCSIQRRH
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHHH
QKVVEFAPSLSLTQKLRDEICNAALKIAGQVGYVNAGTVEFLLDQEGSWYFIEMNPRIQV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEECCCCEEEEEECCCEEE
EHTVTEMITGRNLVQAQILIAEGKKLSDPPINVPNQSAIAMRGYAIQCRITTEDPANNFA
HHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEECEEEEEEEECCCCCCCCC
PDFGTITTYRSSAGFGVRLDAGNAFTGSVITPHYDSLLVKVTSWGLTFDEAAHIMNRSLQ
CCCCCEEEEECCCCCEEEEECCCCEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
EFRVRGVKTNIPFLENVVTHPVFLAGTCDTSFIEKHPELLAISEKKDRATKVLNFLGDVI
HHHHCCCCCCCCHHHHHHCCCEEEEECCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHE
VNGSPGVAKPLKSAEMIEARVPEVDYTVPRPAGSRDLFMKLGAEGLSKWILEQKKLLITD
ECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCEEEEE
TTMRDAHQSLLATRVRTYDLLKIAEPTSYLGAGLFSLECWGGATFDVSMRFLKEDPWQRL
CHHHHHHHHHHHHHHHHHHHHEECCCHHHHHCCCEEEEECCCCEEHHHHHHHHCCHHHHH
HKLSEAIPNILFQMLLRGSNAVGYTNYPDNVVQRFVEEAAASGVDIFRVFDSLNWTRGMT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHH
VAMEAVRKTGKICEAAICYTGDITDPKRDKYPLEYYVAMAKELEQMGAHILAIKDMAGLL
HHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHH
KPMAAHKLVKALKENIGIPVHLHTHDTSSNGNATLLMACQAGVDIVDAALSSISGLTAQP
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCC
NLNALLAALKGTEWDPALDDEGLQHLANYWETVRDYYTPFESGLKSGTAEVYHHEIPGGQ
CHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHEEEEECCCCC
YSNYKPQVAGLGLLDRWEECKEMYFKVNRLFGDIVKVTPSSKVVGDMAMFLVKNNLDVDD
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHH
VFTKGDELSFPESVVGMFKGMLGQPYQGWPAELQKIILKGEEPITCRPGELLEPADFEEK
HHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCHHH
RLEAETKVGHAVNDKDLMSYLLYPHVYPEFDKHRQEYSDTSVIPTPIFFYGLEPGQETSI
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCEE
DIEPGKTLIIKLNAVGKVHPDGTRHIFFELNGQQRQVVVRDQSVQTDEAEREKADKGNAK
EECCCCEEEEEEECCEEECCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHCCCCCC
HIGAPMPGKVLKLNVKAGDVVKAGDVLMVTEAMKMETNIKAKEDGAVAEVKFKEGDKVEK
CCCCCCCCCEEEEEECCCCEEECCCEEEEEHHHHHHCCCCCCCCCCEEEEEECCCCCCCC
EDLVIVMA
CCEEEEEC
>Mature Secondary Structure
MEKRKFRKVMAANRGEIAIRIFRACTELGISTVAIYSEEDKLSLHRYKADEAYLVGKGKA
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCEEEEECCCC
PIDAYLGIDEIISIAKRADVDAIHPGYGFLSENAEFAEACERAGIAFIGPRAEMQRALGD
CHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECCHHHHHHHHCC
KVSARKVAIAAEVPVVPGTEEPIEHEEEALIFAKQHGYPIIIKAAAGGGGRGMRVARNKK
CCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCHHHCCHH
ELLEGLVAARSEAKAAFGNPAVFLERYLENPKHIEVQVLGDHHGNLVHFYERDCSIQRRH
HHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCCHHHHHH
QKVVEFAPSLSLTQKLRDEICNAALKIAGQVGYVNAGTVEFLLDQEGSWYFIEMNPRIQV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEECCCCEEEEEECCCEEE
EHTVTEMITGRNLVQAQILIAEGKKLSDPPINVPNQSAIAMRGYAIQCRITTEDPANNFA
HHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEECEEEEEEEECCCCCCCCC
PDFGTITTYRSSAGFGVRLDAGNAFTGSVITPHYDSLLVKVTSWGLTFDEAAHIMNRSLQ
CCCCCEEEEECCCCCEEEEECCCCEECCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
EFRVRGVKTNIPFLENVVTHPVFLAGTCDTSFIEKHPELLAISEKKDRATKVLNFLGDVI
HHHHCCCCCCCCHHHHHHCCCEEEEECCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHE
VNGSPGVAKPLKSAEMIEARVPEVDYTVPRPAGSRDLFMKLGAEGLSKWILEQKKLLITD
ECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCEEEEE
TTMRDAHQSLLATRVRTYDLLKIAEPTSYLGAGLFSLECWGGATFDVSMRFLKEDPWQRL
CHHHHHHHHHHHHHHHHHHHHEECCCHHHHHCCCEEEEECCCCEEHHHHHHHHCCHHHHH
HKLSEAIPNILFQMLLRGSNAVGYTNYPDNVVQRFVEEAAASGVDIFRVFDSLNWTRGMT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHH
VAMEAVRKTGKICEAAICYTGDITDPKRDKYPLEYYVAMAKELEQMGAHILAIKDMAGLL
HHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHH
KPMAAHKLVKALKENIGIPVHLHTHDTSSNGNATLLMACQAGVDIVDAALSSISGLTAQP
HHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCC
NLNALLAALKGTEWDPALDDEGLQHLANYWETVRDYYTPFESGLKSGTAEVYHHEIPGGQ
CHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHEEEEECCCCC
YSNYKPQVAGLGLLDRWEECKEMYFKVNRLFGDIVKVTPSSKVVGDMAMFLVKNNLDVDD
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHH
VFTKGDELSFPESVVGMFKGMLGQPYQGWPAELQKIILKGEEPITCRPGELLEPADFEEK
HHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCCHHH
RLEAETKVGHAVNDKDLMSYLLYPHVYPEFDKHRQEYSDTSVIPTPIFFYGLEPGQETSI
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCCCCEE
DIEPGKTLIIKLNAVGKVHPDGTRHIFFELNGQQRQVVVRDQSVQTDEAEREKADKGNAK
EECCCCEEEEEEECCEEECCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHCCCCCC
HIGAPMPGKVLKLNVKAGDVVKAGDVLMVTEAMKMETNIKAKEDGAVAEVKFKEGDKVEK
CCCCCCCCCEEEEEECCCCEEECCCEEEEEHHHHHHCCCCCCCCCCEEEEEECCCCCCCC
EDLVIVMA
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]