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The map label for this gene is mcp4 [H]

Identifier: 39997468

GI number: 39997468

Start: 2598947

End: 2601130

Strand: Reverse

Name: mcp4 [H]

Synonym: GSU2372

Alternate gene names: 39997468

Gene position: 2601130-2598947 (Counterclockwise)

Preceding gene: 39997469

Following gene: 39997467

Centisome position: 68.2

GC content: 63.19

Gene sequence:

>2184_bases
ATGTTCAAGGATATGAAACTCGGTTACCGGCTCATAGGCTCCTTTGCCATCATGGCCGCCATCGTTGCTGTCACCGGCTT
CATCGGCATCCGTTCCATCGGGATGGTTGGAAACAGGGTGTCGGATCTCATGCAGACCCGCGCGGATCAGCAGAAGCTGG
CGTTGCAGCTCCAGGCCGCCGAGCGCACCAGCCGCGTCGCCCTGCTGGAGGCGATGATGGGGCACGTGGATACCAGGATC
CTGGCCGCGAACGTGGAGTCCTATCGCAAGAACCGCGACATCTTCAGACGCTACAGCAACGCGCTGCTCAAGGGCGATCC
GGCCCTGGGCATCCGGCCGGACTCCGTCGATACCGTCATGGAAGAGCATGCCAAGGCGCTCCTCGACACCTGGGCCGAGT
ATGAAAAGGTGGCGGACAGGATCATTGCCTACAAGTCCGGGGTCCTGAGCGGTTCGGTGTCTCCTTCGGTGCTCGTCGAG
ACCAGGCTTATCTCCGAGTTGTCCGGGGCAAGCGAATTCGTGGCCCGCGACATCGACGACCTCATCGAGACGGTCAAGGG
GCTGATGCAGGTGGTGGGGCAGGAAACGCGCCAGATCCGGGCCTCGGTCAGCATTACCTTCGTCATTGTCATCATCGGGG
CTGCCGTGCTGGCCTTCGTTTTCGGCGTCGTGGCCACCCGCAACATCATCCGGCGGGTGAACATGATGGTGACGGCGCTG
AACAAGGGAGCGGAAGGGGATCTGACCGTCCGGGTGACCACCGATGCCACGGACGAGCTGTCGCTGCTCGGCCGGGATTT
CAACATCATGCTGGAAATGCTGGGAGAGCTGGTCCGCAAGGTGAACCGCTCCCTGGTGGAGGTGGGGCAGGTCTCCGCCA
ACATCTTCGAGGCTTCGCGCCGGGTCATGGCCGCGGCGGAAGTCCAGGCCGAGGGAGTGTCCCTGACCTCGTCGGCCGTT
GCCGAGATCAATACTTCCATCAAGGAGGTCTCCCGCGGCGTCGACGGCCTTTCCCTTTCCGCCTCGGAAACCTCGTCGTC
GATCCTCGAGATGGCCGCCAGCATCGAAGAGGTGGCCGTGAACGTGGACTCACTGGCCCAGGCCGTTGATGAGGTAAGCT
CCTCGGTGATGGAGATGGCCGCGTCCATCAAGCAGATCGCCAACAGCGTCGTGAGCCTCCAGGATGTGACCACCACCACT
GCCTCTTCCGTGGCCGAGATGGATAGCTCGATCAGGCAGGTCGAGAAGAATGCCATGGAGACCGCATCCATTTCAGAGGG
GGTGCGGCGGGACGCGGAGATGGGCAAGGTCTCCGTCGAAGCGACCATCGCCGGTATCAACGAGATCAAACGCTCTTCCC
GGATCACCTCGGAAGTGATCGAAACCCTTTCCGTCCGGGCCACCGACATCGGCGCGATTCTGTCGGTCATCGACGAAGTG
GCCGAGCAGACCAACCTGCTGGCCCTGAACGCCGCCATCATTGCGGCCCAGGCGGGCGAACACGGCAAGGGTTTCGCCGT
GGTGGCCGACGAGATCAAGGAGCTGGCCGAGCGGACCACCAGCTCCACTCGCGAGATCGCCCAGCTGATCAAAGGGGTCC
AGGATGAAACCGCCCGGGCCGTGGAGGCTATCGAGCTGGCCGAGAAGAGCATCGCCGACGGCGAGGCCCTGTCCCAGAAG
TCGGGCGAAGCCCTGGCCAAGATCGTTACCGGCGTCCAGGGAGCCACGGCCCAGGTGGAGAGCATTGCCCGGGCCACCAT
GGAGCAGGCCAAGGGAAGCCAGATGATCCGTAGCGCCATGGAGCGGGTTTCGGACATGATCGCCCAGGTGGCCGGCGCCA
CCCGGGAGCAGGGCAAGGGGAGCGACATGATCATGGCCGCCGCGGAGCGGATGAAAGGGCTTACCTCCCAGGTCAGGACC
TCAACCCGGGAGCAGAGCAAGGTGGGTGCGTTCATCGCCCGTTCCACCGAGAACATCACCGACATGATTCAGCAGATCAA
GCGGGCCTGCGACGAGCAGTCGCGGGGCAGCGATCAGATCATCCGCGCCGTGGAGGACATCCAGGAGTCGACCTCGACCA
ATCTCGGCTCGGCCCGGATGATGGACGATGCGGTTTCACGGCTGTCCCGCCAGTTGGAAGCCCTTGAGCGGGGTATGAGC
AGTTTCAAGGTGGAGAATCGGTAA

Upstream 100 bases:

>100_bases
TTCCGCACCGGCTTGGGCCTCCTTTTCACTTGATAATGCGGACACCCCTCTGCTATATCAGAACCCATCACCTCTACGTG
TTCCTCCGGAGTTCTCCGCC

Downstream 100 bases:

>100_bases
CCCGGGACCGGGGACCGGGGATCGGCACGATACCTGGAAACCCGGTCCGGCAACCATTCCGAAAGGTTTCCCATGAGCAG
AATTGCCGGCACATTTGCCG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 727; Mature: 727

Protein sequence:

>727_residues
MFKDMKLGYRLIGSFAIMAAIVAVTGFIGIRSIGMVGNRVSDLMQTRADQQKLALQLQAAERTSRVALLEAMMGHVDTRI
LAANVESYRKNRDIFRRYSNALLKGDPALGIRPDSVDTVMEEHAKALLDTWAEYEKVADRIIAYKSGVLSGSVSPSVLVE
TRLISELSGASEFVARDIDDLIETVKGLMQVVGQETRQIRASVSITFVIVIIGAAVLAFVFGVVATRNIIRRVNMMVTAL
NKGAEGDLTVRVTTDATDELSLLGRDFNIMLEMLGELVRKVNRSLVEVGQVSANIFEASRRVMAAAEVQAEGVSLTSSAV
AEINTSIKEVSRGVDGLSLSASETSSSILEMAASIEEVAVNVDSLAQAVDEVSSSVMEMAASIKQIANSVVSLQDVTTTT
ASSVAEMDSSIRQVEKNAMETASISEGVRRDAEMGKVSVEATIAGINEIKRSSRITSEVIETLSVRATDIGAILSVIDEV
AEQTNLLALNAAIIAAQAGEHGKGFAVVADEIKELAERTTSSTREIAQLIKGVQDETARAVEAIELAEKSIADGEALSQK
SGEALAKIVTGVQGATAQVESIARATMEQAKGSQMIRSAMERVSDMIAQVAGATREQGKGSDMIMAAAERMKGLTSQVRT
STREQSKVGAFIARSTENITDMIQQIKRACDEQSRGSDQIIRAVEDIQESTSTNLGSARMMDDAVSRLSRQLEALERGMS
SFKVENR

Sequences:

>Translated_727_residues
MFKDMKLGYRLIGSFAIMAAIVAVTGFIGIRSIGMVGNRVSDLMQTRADQQKLALQLQAAERTSRVALLEAMMGHVDTRI
LAANVESYRKNRDIFRRYSNALLKGDPALGIRPDSVDTVMEEHAKALLDTWAEYEKVADRIIAYKSGVLSGSVSPSVLVE
TRLISELSGASEFVARDIDDLIETVKGLMQVVGQETRQIRASVSITFVIVIIGAAVLAFVFGVVATRNIIRRVNMMVTAL
NKGAEGDLTVRVTTDATDELSLLGRDFNIMLEMLGELVRKVNRSLVEVGQVSANIFEASRRVMAAAEVQAEGVSLTSSAV
AEINTSIKEVSRGVDGLSLSASETSSSILEMAASIEEVAVNVDSLAQAVDEVSSSVMEMAASIKQIANSVVSLQDVTTTT
ASSVAEMDSSIRQVEKNAMETASISEGVRRDAEMGKVSVEATIAGINEIKRSSRITSEVIETLSVRATDIGAILSVIDEV
AEQTNLLALNAAIIAAQAGEHGKGFAVVADEIKELAERTTSSTREIAQLIKGVQDETARAVEAIELAEKSIADGEALSQK
SGEALAKIVTGVQGATAQVESIARATMEQAKGSQMIRSAMERVSDMIAQVAGATREQGKGSDMIMAAAERMKGLTSQVRT
STREQSKVGAFIARSTENITDMIQQIKRACDEQSRGSDQIIRAVEDIQESTSTNLGSARMMDDAVSRLSRQLEALERGMS
SFKVENR
>Mature_727_residues
MFKDMKLGYRLIGSFAIMAAIVAVTGFIGIRSIGMVGNRVSDLMQTRADQQKLALQLQAAERTSRVALLEAMMGHVDTRI
LAANVESYRKNRDIFRRYSNALLKGDPALGIRPDSVDTVMEEHAKALLDTWAEYEKVADRIIAYKSGVLSGSVSPSVLVE
TRLISELSGASEFVARDIDDLIETVKGLMQVVGQETRQIRASVSITFVIVIIGAAVLAFVFGVVATRNIIRRVNMMVTAL
NKGAEGDLTVRVTTDATDELSLLGRDFNIMLEMLGELVRKVNRSLVEVGQVSANIFEASRRVMAAAEVQAEGVSLTSSAV
AEINTSIKEVSRGVDGLSLSASETSSSILEMAASIEEVAVNVDSLAQAVDEVSSSVMEMAASIKQIANSVVSLQDVTTTT
ASSVAEMDSSIRQVEKNAMETASISEGVRRDAEMGKVSVEATIAGINEIKRSSRITSEVIETLSVRATDIGAILSVIDEV
AEQTNLLALNAAIIAAQAGEHGKGFAVVADEIKELAERTTSSTREIAQLIKGVQDETARAVEAIELAEKSIADGEALSQK
SGEALAKIVTGVQGATAQVESIARATMEQAKGSQMIRSAMERVSDMIAQVAGATREQGKGSDMIMAAAERMKGLTSQVRT
STREQSKVGAFIARSTENITDMIQQIKRACDEQSRGSDQIIRAVEDIQESTSTNLGSARMMDDAVSRLSRQLEALERGMS
SFKVENR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=331, Percent_Identity=26.2839879154079, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI2367378, Length=277, Percent_Identity=27.4368231046931, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789453, Length=257, Percent_Identity=27.6264591439689, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788194, Length=293, Percent_Identity=27.9863481228669, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1787690, Length=253, Percent_Identity=30.4347826086957, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 77935; Mature: 77935

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCC
>Mature Secondary Structure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HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]