Click here to switch to the map view.

The map label for this gene is accD [H]

Identifier: 39997466

GI number: 39997466

Start: 2597156

End: 2597998

Strand: Reverse

Name: accD [H]

Synonym: GSU2370

Alternate gene names: 39997466

Gene position: 2597998-2597156 (Counterclockwise)

Preceding gene: 39997467

Following gene: 39997464

Centisome position: 68.11

GC content: 62.04

Gene sequence:

>843_bases
ATGGCGTGGTTCAAACGCGACAAGGCGCCGGGCGCGGCTGACAAGAAGGTGAAGGTTCCCGAGGGGCTCCTGACCAAGTG
CGTGAGCTGCAAGGAAAACCTTCTGACCAAAGACCTGGAGAAGAACATCAATGTCTGCCCCAAGTGCGGACACCATTACC
GGATCTCGGCCCGCCAGAGAATCGATCTGCTCCTGGACCCCGGGAGCTTCACGGAATACGATGCTGCCATGACCTCGGTG
GATGTCCTTGATTTCAAGGACTCCAAGAGCTACAAGGATCGGATCCAGCAGGCGGTTGCCAAGGGGGGATCGCGCGACGC
GGTGATCTGCGGCGAGGGCGCCATCGAGGGTATCCCGGTCCAGATGGCAGTCTTCGACTTCTCCTTCATGGGGGGGAGCA
TGGGGAGCGTGGTGGGCGAGAAGATCACCCGCGCCATCGAGCGGGGGATCGAGAAGCGGACCCCGGTCATCATCATCTCT
GCGTCGGGTGGGGCGCGGATGCAGGAAAGCATCCTGTCCCTGATGCAGATGGCCAAGACCTCGGCGGCCCTGGCCAAGCT
CAAGGAGTTGGGGCTTCCCTATATTTCCATCCTGACCGATCCGACCACCGGCGGGGTGACCGCCAGCTTCTCCATGCTCG
GCGACATCAATATGGCCGAGCCCAAGGCACTCATCGGTTTCGCCGGCCCGCGGGTCATCGAGCAGACCATCCGCCAGAAG
CTCCCCGAAGGGTTCCAGCGGGCCGAGTATCTCCTGGACCATGGCATGGTCGACGTCATCGTGGAGCGCAAGGATATGCG
GGCGAGCCTCGCCCGGATACTTTCCATGCTGTATCGCGGCTGA

Upstream 100 bases:

>100_bases
CGAAGCGATCGGAAATTGACTTTAGCTGACTTTTTTGGTAATAAAACTTTTCAATTTTACTAAAAAATCCGGGATGCGAA
CGTCCCGACGGAGTGACGAC

Downstream 100 bases:

>100_bases
ATCCTCTTACCCCGGGATCTGCACGAAGGGGCCGGTTCGTTGACCGGCCCCTTTTTCGTGCCGGGTCAAATCAGTGGACA
TTTACCCTTTCATTTCCTAT

Product: acetyl-CoA carboxylase, carboxyl transferase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MAWFKRDKAPGAADKKVKVPEGLLTKCVSCKENLLTKDLEKNINVCPKCGHHYRISARQRIDLLLDPGSFTEYDAAMTSV
DVLDFKDSKSYKDRIQQAVAKGGSRDAVICGEGAIEGIPVQMAVFDFSFMGGSMGSVVGEKITRAIERGIEKRTPVIIIS
ASGGARMQESILSLMQMAKTSAALAKLKELGLPYISILTDPTTGGVTASFSMLGDINMAEPKALIGFAGPRVIEQTIRQK
LPEGFQRAEYLLDHGMVDVIVERKDMRASLARILSMLYRG

Sequences:

>Translated_280_residues
MAWFKRDKAPGAADKKVKVPEGLLTKCVSCKENLLTKDLEKNINVCPKCGHHYRISARQRIDLLLDPGSFTEYDAAMTSV
DVLDFKDSKSYKDRIQQAVAKGGSRDAVICGEGAIEGIPVQMAVFDFSFMGGSMGSVVGEKITRAIERGIEKRTPVIIIS
ASGGARMQESILSLMQMAKTSAALAKLKELGLPYISILTDPTTGGVTASFSMLGDINMAEPKALIGFAGPRVIEQTIRQK
LPEGFQRAEYLLDHGMVDVIVERKDMRASLARILSMLYRG
>Mature_279_residues
AWFKRDKAPGAADKKVKVPEGLLTKCVSCKENLLTKDLEKNINVCPKCGHHYRISARQRIDLLLDPGSFTEYDAAMTSVD
VLDFKDSKSYKDRIQQAVAKGGSRDAVICGEGAIEGIPVQMAVFDFSFMGGSMGSVVGEKITRAIERGIEKRTPVIIISA
SGGARMQESILSLMQMAKTSAALAKLKELGLPYISILTDPTTGGVTASFSMLGDINMAEPKALIGFAGPRVIEQTIRQKL
PEGFQRAEYLLDHGMVDVIVERKDMRASLARILSMLYRG

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=191, Percent_Identity=30.3664921465969, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI295821216, Length=211, Percent_Identity=27.4881516587678, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1788655, Length=277, Percent_Identity=57.7617328519856, Blast_Score=343, Evalue=6e-96,
Organism=Caenorhabditis elegans, GI25147362, Length=190, Percent_Identity=28.9473684210526, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25147359, Length=190, Percent_Identity=28.9473684210526, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 30535; Mature: 30404

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWFKRDKAPGAADKKVKVPEGLLTKCVSCKENLLTKDLEKNINVCPKCGHHYRISARQR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCC
IDLLLDPGSFTEYDAAMTSVDVLDFKDSKSYKDRIQQAVAKGGSRDAVICGEGAIEGIPV
EEEEECCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCE
QMAVFDFSFMGGSMGSVVGEKITRAIERGIEKRTPVIIISASGGARMQESILSLMQMAKT
EEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
SAALAKLKELGLPYISILTDPTTGGVTASFSMLGDINMAEPKALIGFAGPRVIEQTIRQK
HHHHHHHHHHCCCEEEEEECCCCCCCEEHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHH
LPEGFQRAEYLLDHGMVDVIVERKDMRASLARILSMLYRG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AWFKRDKAPGAADKKVKVPEGLLTKCVSCKENLLTKDLEKNINVCPKCGHHYRISARQR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCC
IDLLLDPGSFTEYDAAMTSVDVLDFKDSKSYKDRIQQAVAKGGSRDAVICGEGAIEGIPV
EEEEECCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCE
QMAVFDFSFMGGSMGSVVGEKITRAIERGIEKRTPVIIISASGGARMQESILSLMQMAKT
EEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
SAALAKLKELGLPYISILTDPTTGGVTASFSMLGDINMAEPKALIGFAGPRVIEQTIRQK
HHHHHHHHHHCCCEEEEEECCCCCCCEEHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHH
LPEGFQRAEYLLDHGMVDVIVERKDMRASLARILSMLYRG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA