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The map label for this gene is rodA [H]

Identifier: 39997176

GI number: 39997176

Start: 2284208

End: 2285308

Strand: Reverse

Name: rodA [H]

Synonym: GSU2078

Alternate gene names: 39997176

Gene position: 2285308-2284208 (Counterclockwise)

Preceding gene: 39997177

Following gene: 39997174

Centisome position: 59.92

GC content: 56.68

Gene sequence:

>1101_bases
ATGATCGACCGACGACTCATCACCAACTTCGACTGGATGCTGCTGGGACTCGTGCTGCTTATCTGTGCGGTAGGAGTTGT
GAATATCTACAGCGCCTCATCGTCGTACGTTCTGTCGGGCACACCTTACTATCTCAAGCAGATGTCCTGGGTTTTGGTCG
GCCTCGCCATCATGCTGCTGGTCTGCAGCATCGACTACCACCTGCTGGAGGATGTTGCCTACTGGTTCTACGGCATCCTG
TTCCTTCTCCTGCTCGTGGTGCTGGCTTTCGGCAAGACTTCAATGGGAGCCACCCGATGGCTTCACCTGGGATTTATCAG
TGTTCAGCCATCTGAACCCATGAAAATCATAGGGATCATCACCATGGCCCGCATCCTGGCCAATATTCCGGTGTCAGGCG
GCCTGGGGCTGCGGGAGCTGGCCTTCCCCGCCCTCATGATCGGTGCGCCCGCCATTCTCATCATGAAGCAGCCCGATCTC
GGCACGGCGATACTTGTCATCCTCATTGCCGGATCCATGCTCGCGTTTGTCGGCATCCGTCTTTCCGCGCTGGCTGCCGT
ATGCATTGCCACCGTACCGGCCGTCTGGCTTGGCTGGCATTACTATCTCAGGGATTATCAGAAAAACAGGGTTCTCAATT
TTCTGGATCCTGAGAGGGACCCGCTCGGCACGGGGTACCACATCATCCAGAGCAAGATTGCCGTGGGATCGGGCGGCCTG
TTCGGCAAGGGATTTCTCCAGGGGACCCAGAGCCAGCTCCGCTTCCTGCCGGAACAGCACACGGACTTCGCATTTTCCGT
TTTTGCCGAGGAATGGGGATTTGTGGGGAGTCTTGTTGTTCTGCTGCTTTACGCGGTGCTCACCCTGTGGGGGCTCCAGA
TTGCACGGCGCTGCAACGACCGTTTCGGAAGCCTCGTGGCTGTGGGCGTCACGGCAATGCTTTTCTGGCACATCATCATC
AACATCGGTATGGTAATCGGACTCTTCCCCGTGGTCGGGGTGCCATTGCCTCTGTTTTCCTACGGCGGCACATCCATGAT
CACGTCAATGACGGGCATTGGCATTCTCCTTAACATCAGCATGCGACGCTTCATGTTCTAG

Upstream 100 bases:

>100_bases
GGTCAAAGCCGGGAAGGGAACTGCCGCCGGGGACGACGGCTCCGGGGAAAACGCGACATCCGACGAAGGGGCGCAGCCCC
GCGAGGATCAGGAATAGACA

Downstream 100 bases:

>100_bases
GAGAAGGCGGCCCGCCTTACGCAACCTTCTTGTTGAGCAGAACAATCCCTTCAAATTCCTGAATCCAGATCGCACCACAG
GTGGTGCATTCCAGCAGATT

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MIDRRLITNFDWMLLGLVLLICAVGVVNIYSASSSYVLSGTPYYLKQMSWVLVGLAIMLLVCSIDYHLLEDVAYWFYGIL
FLLLLVVLAFGKTSMGATRWLHLGFISVQPSEPMKIIGIITMARILANIPVSGGLGLRELAFPALMIGAPAILIMKQPDL
GTAILVILIAGSMLAFVGIRLSALAAVCIATVPAVWLGWHYYLRDYQKNRVLNFLDPERDPLGTGYHIIQSKIAVGSGGL
FGKGFLQGTQSQLRFLPEQHTDFAFSVFAEEWGFVGSLVVLLLYAVLTLWGLQIARRCNDRFGSLVAVGVTAMLFWHIII
NIGMVIGLFPVVGVPLPLFSYGGTSMITSMTGIGILLNISMRRFMF

Sequences:

>Translated_366_residues
MIDRRLITNFDWMLLGLVLLICAVGVVNIYSASSSYVLSGTPYYLKQMSWVLVGLAIMLLVCSIDYHLLEDVAYWFYGIL
FLLLLVVLAFGKTSMGATRWLHLGFISVQPSEPMKIIGIITMARILANIPVSGGLGLRELAFPALMIGAPAILIMKQPDL
GTAILVILIAGSMLAFVGIRLSALAAVCIATVPAVWLGWHYYLRDYQKNRVLNFLDPERDPLGTGYHIIQSKIAVGSGGL
FGKGFLQGTQSQLRFLPEQHTDFAFSVFAEEWGFVGSLVVLLLYAVLTLWGLQIARRCNDRFGSLVAVGVTAMLFWHIII
NIGMVIGLFPVVGVPLPLFSYGGTSMITSMTGIGILLNISMRRFMF
>Mature_366_residues
MIDRRLITNFDWMLLGLVLLICAVGVVNIYSASSSYVLSGTPYYLKQMSWVLVGLAIMLLVCSIDYHLLEDVAYWFYGIL
FLLLLVVLAFGKTSMGATRWLHLGFISVQPSEPMKIIGIITMARILANIPVSGGLGLRELAFPALMIGAPAILIMKQPDL
GTAILVILIAGSMLAFVGIRLSALAAVCIATVPAVWLGWHYYLRDYQKNRVLNFLDPERDPLGTGYHIIQSKIAVGSGGL
FGKGFLQGTQSQLRFLPEQHTDFAFSVFAEEWGFVGSLVVLLLYAVLTLWGLQIARRCNDRFGSLVAVGVTAMLFWHIII
NIGMVIGLFPVVGVPLPLFSYGGTSMITSMTGIGILLNISMRRFMF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=345, Percent_Identity=45.7971014492754, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1786277, Length=362, Percent_Identity=30.939226519337, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40222; Mature: 40222

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDRRLITNFDWMLLGLVLLICAVGVVNIYSASSSYVLSGTPYYLKQMSWVLVGLAIMLL
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHH
VCSIDYHLLEDVAYWFYGILFLLLLVVLAFGKTSMGATRWLHLGFISVQPSEPMKIIGII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEEEEECCCCCHHHHHHH
TMARILANIPVSGGLGLRELAFPALMIGAPAILIMKQPDLGTAILVILIAGSMLAFVGIR
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
LSALAAVCIATVPAVWLGWHYYLRDYQKNRVLNFLDPERDPLGTGYHIIQSKIAVGSGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
FGKGFLQGTQSQLRFLPEQHTDFAFSVFAEEWGFVGSLVVLLLYAVLTLWGLQIARRCND
CCHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGSLVAVGVTAMLFWHIIINIGMVIGLFPVVGVPLPLFSYGGTSMITSMTGIGILLNIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHEEHH
MRRFMF
HHHHCC
>Mature Secondary Structure
MIDRRLITNFDWMLLGLVLLICAVGVVNIYSASSSYVLSGTPYYLKQMSWVLVGLAIMLL
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHH
VCSIDYHLLEDVAYWFYGILFLLLLVVLAFGKTSMGATRWLHLGFISVQPSEPMKIIGII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEEEEECCCCCHHHHHHH
TMARILANIPVSGGLGLRELAFPALMIGAPAILIMKQPDLGTAILVILIAGSMLAFVGIR
HHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
LSALAAVCIATVPAVWLGWHYYLRDYQKNRVLNFLDPERDPLGTGYHIIQSKIAVGSGGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCC
FGKGFLQGTQSQLRFLPEQHTDFAFSVFAEEWGFVGSLVVLLLYAVLTLWGLQIARRCND
CCHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGSLVAVGVTAMLFWHIIINIGMVIGLFPVVGVPLPLFSYGGTSMITSMTGIGILLNIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHEEHH
MRRFMF
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]