Click here to switch to the map view.

The map label for this gene is paaK [H]

Identifier: 39997149

GI number: 39997149

Start: 2252242

End: 2253543

Strand: Reverse

Name: paaK [H]

Synonym: GSU2051

Alternate gene names: 39997149

Gene position: 2253543-2252242 (Counterclockwise)

Preceding gene: 39997150

Following gene: 39997148

Centisome position: 59.08

GC content: 63.44

Gene sequence:

>1302_bases
ATGCTGACCCGCTTTCCCGCCCACTACTCATCTCCCGCGGAGCTTGAACGGCTCCAGCTCGACGGCCTGCGCTGGACCGT
GAACCACGCCTGGCGCAACTCGCCCTTTTACCGCAGCCGGCTCGAACTGGCGGGCGTGACGCCCGACGACATCGCGAGCC
TCGCGGATATTGCGAAGCTTCCCTTTACCTCTGCCGACGATCTGCGTGACGGCTATCCCTTCCCCCTTCGTGCGGCCTCC
CATGAGCAGCTCGTCCGGATTCACTCATCCTCGGGGACAACAGGGAAGCGGAAAATCCTTTGCTACACCCAGAAAGATGT
GGATGACTGGGCCGACATGTTTTGCCGTTGCTACGAGATGGCCGGCGTCACCCGTGAAGACCGGGTGCAGATCTGCGTCG
GGTATGGCCTCTGGACCGCCGGAGCGGGTTTTCAGCTGGGATGCGAGCGGTACGGTGCCCTGGCAGTGCCCGTGGGGCCG
GGAAACCTCGATATCCAGACCACTTTCCTGGTGGATCTCCAGTCGACGGTGGTCTGCTGCACCGCCTCCATGGGGCTGCT
CCTGGCCGAAGAGGTCCAGCGGCGCAATCTGCGCGACAAGATCGCCGTGCGCAAGGTGATCCTCGGTGCCGAACGTTCAA
GCGAGGCGATTCTTGCCAAGATCCGCGAATGCCTCGGTGCCGAATCGGTTCACGACATCACCGGCCTCACCGAGGTGTAC
GGTCCGGGCACGGGGCTTTCCTGCGGAGTGCCGGGCGCAGATGGCTCCATTCACTACTGGGCCGACTACTATCTCCTTGA
AATCCTCGACCCGGAAACACTCCAGCCGGTGCAGCCAGGGGAGGTGGGGGAGATGGTCTTCACTACGCTCTGCAAGGAGG
GGGGACCGCTCATCCGCTATCGCTCCCGGGATCTGACCCGCCTCGTGCCGGGCGATTGCCCCTGTGGCTGCGTTCTTCCC
CGTCACGACCGGATACTCGGGCGTTCCGACGATGTGGTGATTTTCCGGGGGGTCAACATCTATCCCGGACAGATTGATGA
GATTCTCGACCGGATCGACGGGCTCGGCAGTGAATTCCAGGTGGTTCTGGACCGGGGTGCCGATGGTCGCGACTACATGA
CCATCCGGGTGGAGCGGGCCGAAGATGCTGCGCCCACAGCGGATGCCCTCCTCAGCAAGGCGATCGTGTCGGGTGTGAAG
CATTCCCTGATGGTCTCCTGCGAGGTGGATCTCCTCCCCTACGGCGAGCTCCCCCGATCCGAGCGCAAGACCCGCCGCAT
GTTCGACAACCGCGCCTACTGA

Upstream 100 bases:

>100_bases
GGCGCTCCGGGCCGCATCTCTCAAGGCCCTGCGTCTCGGCATGGAGCGGGCGGAGGCTTGATTTTCCGGTAATCCTTTCC
GATGGAGGTTGCATCCCCCT

Downstream 100 bases:

>100_bases
CCCGTAACCGAACCCGTCAAGCCGGTGGAGCGGGGCGGACACCGGTGCCCAGGTGCGCGGCCGGCCAGGCCGCAGGGAAC
AGCCTTGGCCGCTTTTGTCC

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MLTRFPAHYSSPAELERLQLDGLRWTVNHAWRNSPFYRSRLELAGVTPDDIASLADIAKLPFTSADDLRDGYPFPLRAAS
HEQLVRIHSSSGTTGKRKILCYTQKDVDDWADMFCRCYEMAGVTREDRVQICVGYGLWTAGAGFQLGCERYGALAVPVGP
GNLDIQTTFLVDLQSTVVCCTASMGLLLAEEVQRRNLRDKIAVRKVILGAERSSEAILAKIRECLGAESVHDITGLTEVY
GPGTGLSCGVPGADGSIHYWADYYLLEILDPETLQPVQPGEVGEMVFTTLCKEGGPLIRYRSRDLTRLVPGDCPCGCVLP
RHDRILGRSDDVVIFRGVNIYPGQIDEILDRIDGLGSEFQVVLDRGADGRDYMTIRVERAEDAAPTADALLSKAIVSGVK
HSLMVSCEVDLLPYGELPRSERKTRRMFDNRAY

Sequences:

>Translated_433_residues
MLTRFPAHYSSPAELERLQLDGLRWTVNHAWRNSPFYRSRLELAGVTPDDIASLADIAKLPFTSADDLRDGYPFPLRAAS
HEQLVRIHSSSGTTGKRKILCYTQKDVDDWADMFCRCYEMAGVTREDRVQICVGYGLWTAGAGFQLGCERYGALAVPVGP
GNLDIQTTFLVDLQSTVVCCTASMGLLLAEEVQRRNLRDKIAVRKVILGAERSSEAILAKIRECLGAESVHDITGLTEVY
GPGTGLSCGVPGADGSIHYWADYYLLEILDPETLQPVQPGEVGEMVFTTLCKEGGPLIRYRSRDLTRLVPGDCPCGCVLP
RHDRILGRSDDVVIFRGVNIYPGQIDEILDRIDGLGSEFQVVLDRGADGRDYMTIRVERAEDAAPTADALLSKAIVSGVK
HSLMVSCEVDLLPYGELPRSERKTRRMFDNRAY
>Mature_433_residues
MLTRFPAHYSSPAELERLQLDGLRWTVNHAWRNSPFYRSRLELAGVTPDDIASLADIAKLPFTSADDLRDGYPFPLRAAS
HEQLVRIHSSSGTTGKRKILCYTQKDVDDWADMFCRCYEMAGVTREDRVQICVGYGLWTAGAGFQLGCERYGALAVPVGP
GNLDIQTTFLVDLQSTVVCCTASMGLLLAEEVQRRNLRDKIAVRKVILGAERSSEAILAKIRECLGAESVHDITGLTEVY
GPGTGLSCGVPGADGSIHYWADYYLLEILDPETLQPVQPGEVGEMVFTTLCKEGGPLIRYRSRDLTRLVPGDCPCGCVLP
RHDRILGRSDDVVIFRGVNIYPGQIDEILDRIDGLGSEFQVVLDRGADGRDYMTIRVERAEDAAPTADALLSKAIVSGVK
HSLMVSCEVDLLPYGELPRSERKTRRMFDNRAY

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=431, Percent_Identity=39.2111368909513, Blast_Score=303, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 47896; Mature: 47896

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTRFPAHYSSPAELERLQLDGLRWTVNHAWRNSPFYRSRLELAGVTPDDIASLADIAKL
CCCCCCCCCCCHHHHHHHEECCEEEEEEHHHCCCCCHHHHHEECCCCHHHHHHHHHHHHC
PFTSADDLRDGYPFPLRAASHEQLVRIHSSSGTTGKRKILCYTQKDVDDWADMFCRCYEM
CCCCCHHHCCCCCCCCCCCCCHHEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
AGVTREDRVQICVGYGLWTAGAGFQLGCERYGALAVPVGPGNLDIQTTFLVDLQSTVVCC
HCCCCCCCEEEEEEECCHHCCCCCEECHHHCCEEEEEECCCCCEEEEEEEEEHHHHHHHH
TASMGLLLAEEVQRRNLRDKIAVRKVILGAERSSEAILAKIRECLGAESVHDITGLTEVY
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHCHHHHC
GPGTGLSCGVPGADGSIHYWADYYLLEILDPETLQPVQPGEVGEMVFTTLCKEGGPLIRY
CCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
RSRDLTRLVPGDCPCGCVLPRHDRILGRSDDVVIFRGVNIYPGQIDEILDRIDGLGSEFQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEE
VVLDRGADGRDYMTIRVERAEDAAPTADALLSKAIVSGVKHSLMVSCEVDLLPYGELPRS
EEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCH
ERKTRRMFDNRAY
HHHHHHHHHCCCC
>Mature Secondary Structure
MLTRFPAHYSSPAELERLQLDGLRWTVNHAWRNSPFYRSRLELAGVTPDDIASLADIAKL
CCCCCCCCCCCHHHHHHHEECCEEEEEEHHHCCCCCHHHHHEECCCCHHHHHHHHHHHHC
PFTSADDLRDGYPFPLRAASHEQLVRIHSSSGTTGKRKILCYTQKDVDDWADMFCRCYEM
CCCCCHHHCCCCCCCCCCCCCHHEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
AGVTREDRVQICVGYGLWTAGAGFQLGCERYGALAVPVGPGNLDIQTTFLVDLQSTVVCC
HCCCCCCCEEEEEEECCHHCCCCCEECHHHCCEEEEEECCCCCEEEEEEEEEHHHHHHHH
TASMGLLLAEEVQRRNLRDKIAVRKVILGAERSSEAILAKIRECLGAESVHDITGLTEVY
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHCHHHHC
GPGTGLSCGVPGADGSIHYWADYYLLEILDPETLQPVQPGEVGEMVFTTLCKEGGPLIRY
CCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEE
RSRDLTRLVPGDCPCGCVLPRHDRILGRSDDVVIFRGVNIYPGQIDEILDRIDGLGSEFQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEE
VVLDRGADGRDYMTIRVERAEDAAPTADALLSKAIVSGVKHSLMVSCEVDLLPYGELPRS
EEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCH
ERKTRRMFDNRAY
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]