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The map label for this gene is aroQ

Identifier: 39997120

GI number: 39997120

Start: 2215167

End: 2215619

Strand: Reverse

Name: aroQ

Synonym: GSU2022

Alternate gene names: 39997120

Gene position: 2215619-2215167 (Counterclockwise)

Preceding gene: 39997121

Following gene: 39997119

Centisome position: 58.09

GC content: 58.94

Gene sequence:

>453_bases
ATGCGCATTCTCGTGGTGCACGGTCCGAACCTTAATATGCTGGGAACCCGCGAACCGGGCATCTATGGCACGTTAACACT
TGATCGGATCAATGAGTCTCTGGTAGCCTTGGCCGATGAACTGGGCTGCACGATTTCCCCGTTCCAGTCCAACAGCGAAG
GGGCACTGGTCGATGCCATCCAGGCTGCGGCGGGAACCTGTGACGGCATTCTCATCAATCCGGCCGCATATACCCACACC
AGTGTCGCCATTCGCGACGCCCTCGCAGCTGTGGCGTTGCCGGTGGTGGAGGTGCATCTCTCGAATATCCACCGCCGGGA
GGAGTTCCGGTCTCATAGTTTTGTTGCAGCCGTCGCGGTGGGGCAGATCACGGGGTTCGGCGCCGACAGCTACCTGCTCG
GGTTGCGCGCCCTTTTTACCCACATTGAAAAAGGGATTGTCACCAAGGGTTGA

Upstream 100 bases:

>100_bases
GACGGCAACTACGGCAAAGGGCGCTACCTGTTGCGCCTTGCCGCCCCGAAGTTGCGCGAACTGCTGTCATAGCCGGCCTC
TCCGGAAAAGGAGTTGTTGC

Downstream 100 bases:

>100_bases
AACATGTTACAAAACAGGCTCAATAAAGCCCGGAGTCATGCCGAAAAACACGATGTGGACGCCATCGTGTTTTTTAACAT
GAGTAACGTTCGTTACCTTT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MRILVVHGPNLNMLGTREPGIYGTLTLDRINESLVALADELGCTISPFQSNSEGALVDAIQAAAGTCDGILINPAAYTHT
SVAIRDALAAVALPVVEVHLSNIHRREEFRSHSFVAAVAVGQITGFGADSYLLGLRALFTHIEKGIVTKG

Sequences:

>Translated_150_residues
MRILVVHGPNLNMLGTREPGIYGTLTLDRINESLVALADELGCTISPFQSNSEGALVDAIQAAAGTCDGILINPAAYTHT
SVAIRDALAAVALPVVEVHLSNIHRREEFRSHSFVAAVAVGQITGFGADSYLLGLRALFTHIEKGIVTKG
>Mature_150_residues
MRILVVHGPNLNMLGTREPGIYGTLTLDRINESLVALADELGCTISPFQSNSEGALVDAIQAAAGTCDGILINPAAYTHT
SVAIRDALAAVALPVVEVHLSNIHRREEFRSHSFVAAVAVGQITGFGADSYLLGLRALFTHIEKGIVTKG

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_GEOSL (Q74BL9)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_953071.1
- ProteinModelPortal:   Q74BL9
- SMR:   Q74BL9
- GeneID:   2688028
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU2022
- NMPDR:   fig|243231.1.peg.2009
- TIGR:   GSU2022
- HOGENOM:   HBG284657
- OMA:   HSYIAPI
- ProtClustDB:   PRK05395
- BioCyc:   GSUL243231:GSU_2022-MONOMER
- BRENDA:   4.2.1.10
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15833; Mature: 15833

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 99-99 BINDING 73-73 BINDING 79-79 BINDING 86-86 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVVHGPNLNMLGTREPGIYGTLTLDRINESLVALADELGCTISPFQSNSEGALVDAI
CEEEEEECCCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHCCEECCCCCCCCCHHHHHH
QAAAGTCDGILINPAAYTHTSVAIRDALAAVALPVVEVHLSNIHRREEFRSHSFVAAVAV
HHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GQITGFGADSYLLGLRALFTHIEKGIVTKG
HHHCCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRILVVHGPNLNMLGTREPGIYGTLTLDRINESLVALADELGCTISPFQSNSEGALVDAI
CEEEEEECCCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHCCEECCCCCCCCCHHHHHH
QAAAGTCDGILINPAAYTHTSVAIRDALAAVALPVVEVHLSNIHRREEFRSHSFVAAVAV
HHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GQITGFGADSYLLGLRALFTHIEKGIVTKG
HHHCCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA