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The map label for this gene is hprK

Identifier: 39996983

GI number: 39996983

Start: 2063343

End: 2064329

Strand: Reverse

Name: hprK

Synonym: GSU1885

Alternate gene names: 39996983

Gene position: 2064329-2063343 (Counterclockwise)

Preceding gene: 39996984

Following gene: 39996982

Centisome position: 54.12

GC content: 57.14

Gene sequence:

>987_bases
ATGGTTCCGCACCCAGGAAAACCACCGTTGAACAGCATCAGTCTCGCTATTCAGGATCTTCTCGACGATACGGAGTACGG
GCTCGAACTCGTGCTGCTCGCCGGTGGCGCGGGTGTGGGGCACCGCATTCACAGTTCCCGCATCCAGAAGCCGGGGCTCG
CCCTTACCGGCTATACTGAGCATCTGCACCCCGACCGGGTCCAGGTGCTCGGCAATACGGAGATTTCGTATCTCCAGCAA
ATTTCGGAACAGCAGGCACTCATCCATATCCAAAAGCTCTGCAGCTACCCCATCTCTTGCTTTATCGTTACCAAGGGACT
CGATCCGCCCGGTTTTCTCAAGGCAGAAGCGGAAAGGGCCGGGATTCCCCTGTTGGTGACGCCGCACCAGTCCTCCACCT
TTATTTCGCTGATCACGAAATTTCTGGAAGAGCGTCTTCTCCCCACTACCCACATTCACGGTGTTCTGGTTGATGTCCTG
GGGGTAGGGGTGCTGATCCTGGGTAAGAGCGGCATCGGCAAGAGCGAGTGCGCCCTTGATCTCGTGATCCGGGGACATCG
CCTGGTGGCGGACGATGTGGTGTATGTCAAGAAGAAGATGCCGGCGGCGCTGGTGGGTCAGGCAGCCGAAGCGATCCAGC
ATCACATGGAGATCCGGGGGCTCGGTGTCATCAACATCAAGAATCTGTTCGGCGTTTCTTCCATTCGCGAAAAAAAGATC
ATCGACATGGTGATCGAACTCGTCGATTGGGATCCTGTCCAGGAGTACGACCGCCTCGGCCTGGATGACGAGGTGTATGC
CATCCTTGACGTGGAACTGCCCCACATTAAGATTCCCGTCCGTCCGGGCCGCAACCTTACCTCCATCATTGAAGTGGCGG
CTCGCAATCACCTTCTCAAGGGCATGGGCTATCACTCCGCCCGCGAATTCCACGAAAAACTTCTGGCCCGCATGGAAGTC
CGCCCACTCGGAAACGAGGTGGAATAG

Upstream 100 bases:

>100_bases
CGGCCATCGTGAGTCGATCATTACGGGGATTCACATCATCCGGCGAGTTGACAGACAACTCGCCGGATGTGTGCTTTCCC
GGTTACCGGAGCGGGCCGGC

Downstream 100 bases:

>100_bases
CCATGCGCGTTCTGGTGATCACAGGGCTTTCGGGCTCCGGTAAATCGACGGCGGTGCGTGTACTGGAGGACGAGGGGTTT
TTCTGCGTCGACAACCTTCC

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MVPHPGKPPLNSISLAIQDLLDDTEYGLELVLLAGGAGVGHRIHSSRIQKPGLALTGYTEHLHPDRVQVLGNTEISYLQQ
ISEQQALIHIQKLCSYPISCFIVTKGLDPPGFLKAEAERAGIPLLVTPHQSSTFISLITKFLEERLLPTTHIHGVLVDVL
GVGVLILGKSGIGKSECALDLVIRGHRLVADDVVYVKKKMPAALVGQAAEAIQHHMEIRGLGVINIKNLFGVSSIREKKI
IDMVIELVDWDPVQEYDRLGLDDEVYAILDVELPHIKIPVRPGRNLTSIIEVAARNHLLKGMGYHSAREFHEKLLARMEV
RPLGNEVE

Sequences:

>Translated_328_residues
MVPHPGKPPLNSISLAIQDLLDDTEYGLELVLLAGGAGVGHRIHSSRIQKPGLALTGYTEHLHPDRVQVLGNTEISYLQQ
ISEQQALIHIQKLCSYPISCFIVTKGLDPPGFLKAEAERAGIPLLVTPHQSSTFISLITKFLEERLLPTTHIHGVLVDVL
GVGVLILGKSGIGKSECALDLVIRGHRLVADDVVYVKKKMPAALVGQAAEAIQHHMEIRGLGVINIKNLFGVSSIREKKI
IDMVIELVDWDPVQEYDRLGLDDEVYAILDVELPHIKIPVRPGRNLTSIIEVAARNHLLKGMGYHSAREFHEKLLARMEV
RPLGNEVE
>Mature_328_residues
MVPHPGKPPLNSISLAIQDLLDDTEYGLELVLLAGGAGVGHRIHSSRIQKPGLALTGYTEHLHPDRVQVLGNTEISYLQQ
ISEQQALIHIQKLCSYPISCFIVTKGLDPPGFLKAEAERAGIPLLVTPHQSSTFISLITKFLEERLLPTTHIHGVLVDVL
GVGVLILGKSGIGKSECALDLVIRGHRLVADDVVYVKKKMPAALVGQAAEAIQHHMEIRGLGVINIKNLFGVSSIREKKI
IDMVIELVDWDPVQEYDRLGLDDEVYAILDVELPHIKIPVRPGRNLTSIIEVAARNHLLKGMGYHSAREFHEKLLARMEV
RPLGNEVE

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_GEOSL (P61323)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952934.1
- ProteinModelPortal:   P61323
- SMR:   P61323
- GeneID:   2685611
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1885
- NMPDR:   fig|243231.1.peg.1872
- TIGR:   GSU1885
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- BioCyc:   GSUL243231:GSU_1885-MONOMER
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126
- TIGRFAMs:   TIGR00679

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 36118; Mature: 36118

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: ACT_SITE 153-153 ACT_SITE 174-174 ACT_SITE 192-192 ACT_SITE 258-258

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPHPGKPPLNSISLAIQDLLDDTEYGLELVLLAGGAGVGHRIHSSRIQKPGLALTGYTE
CCCCCCCCCHHHHHHHHHHHHCCHHCCEEEEEEECCCCCCHHHHHHHCCCCCCEEECCHH
HLHPDRVQVLGNTEISYLQQISEQQALIHIQKLCSYPISCFIVTKGLDPPGFLKAEAERA
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEECCHHHC
GIPLLVTPHQSSTFISLITKFLEERLLPTTHIHGVLVDVLGVGVLILGKSGIGKSECALD
CCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHEE
LVIRGHRLVADDVVYVKKKMPAALVGQAAEAIQHHMEIRGLGVINIKNLFGVSSIREKKI
EEEECCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCHHHHHHHHH
IDMVIELVDWDPVQEYDRLGLDDEVYAILDVELPHIKIPVRPGRNLTSIIEVAARNHLLK
HHHHHHHHCCCCHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHH
GMGYHSAREFHEKLLARMEVRPLGNEVE
CCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVPHPGKPPLNSISLAIQDLLDDTEYGLELVLLAGGAGVGHRIHSSRIQKPGLALTGYTE
CCCCCCCCCHHHHHHHHHHHHCCHHCCEEEEEEECCCCCCHHHHHHHCCCCCCEEECCHH
HLHPDRVQVLGNTEISYLQQISEQQALIHIQKLCSYPISCFIVTKGLDPPGFLKAEAERA
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEECCHHHC
GIPLLVTPHQSSTFISLITKFLEERLLPTTHIHGVLVDVLGVGVLILGKSGIGKSECALD
CCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHEE
LVIRGHRLVADDVVYVKKKMPAALVGQAAEAIQHHMEIRGLGVINIKNLFGVSSIREKKI
EEEECCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCHHHHHHHHH
IDMVIELVDWDPVQEYDRLGLDDEVYAILDVELPHIKIPVRPGRNLTSIIEVAARNHLLK
HHHHHHHHCCCCHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHH
GMGYHSAREFHEKLLARMEVRPLGNEVE
CCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA