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The map label for this gene is glnA [H]

Identifier: 39996934

GI number: 39996934

Start: 2000819

End: 2002231

Strand: Reverse

Name: glnA [H]

Synonym: GSU1835

Alternate gene names: 39996934

Gene position: 2002231-2000819 (Counterclockwise)

Preceding gene: 39996935

Following gene: 39996933

Centisome position: 52.49

GC content: 59.24

Gene sequence:

>1413_bases
ATGACACCACAAGAGGTAGTAAGCTTCGCCAAAGAGAACGGCGCGCTGATGGTCGATTACAAGTTCATGGACTTCGTCGG
CATCTGGCAGCATGTTTCCGTGCCCATTTCGGAGTTCGGTGAAGATACCTTTGAGGAAGGCCAGGGTTTCGACGGCTCCT
CCATCCGCGGCTGGCAGCCCATCCATGCGTCCGACATGATCCTCCTGCCGGACCCCGCAACGGCCAAGATGGATCCGTTC
ATCGCGGTGCCGACCCTTTCACTCATCTGCAATGTCTTCGATCCGATCACCAAGGAAGACTACACTCGCGATCCGCGCAA
CATTGCCCGTAAGGCCGAGGCGTACCTGAAGTCGACCGGCCTCGGCGATACCGCTTTCTTCGGTCCCGAGGCCGAGTTCT
TCATTTTTGACGACGTCCGGTACGATTCGACCTCCAACCAGTCGTTCTACATGGTTGATTCGGTGGAGGGTGCCTGGAAC
ACCGGCCGCGAAGAGTTCCCGAACCTGGGCTACAAGCCGCGCCACAAGGAAGGTTATTTCCCCGTTTCCCCGACCGACTC
CCAGAACGATCTCCGCAACGAGATGGTCATGGAGCTCCAGAAGGTCGGCATCCGGGTCGAGTGTCAGCATCACGAAGTTG
CCTCCGGCGGCCAGGCCGAAATCGACATGCGGTTCTCCTCCCTCGTCGACATGGCCGACCAGCTCCAGTGGTTCAAGTAT
GTCATCAAGAACGTTGCCTACCGTAACGGCAAGACCGTTACCTTCATGCCCAAGCCGCTCTATGGCGACAACGGCTCCGG
CATGCACTGCCACATGTCCATCTGGAAGGACGGCCAGAACCTCTTTGCCGGCGACAAGTACGGCGGACTTTCCCAGATGG
CACTCTGGTACATTGGTGGTATCATCAAGCACGCCAAGGCTCTCTGTGCCCTGACCAACCCGACCACCAACTCGTACAAG
CGTCTGGTGCCGGGTTTCGAGGCACCGGTGAACATGGCTTACTCCAGCCGTAACCGTTCCGCCTCCATCCGGATACCCAT
GATGTCCACCAACCCGAAGGCCAAGCGGATCGAGTACCGGACTCCGGACCCCTCCTGCAACGGCTATCTTGCCTTCGCCG
CCATGCTGATGGCCGGCCTCGACGGCATCGAGAACAAGATCGATCCGGGGCAACCGCTGGATAAGGACATCTACGGGCTT
TCCCCCGAGGAGCTCAAGAACATCCCGTCCGCTCCGGGAAGCCTTGAAGAAGCCCTCAAGGCCCTGGAGGCCGACCACGA
GTTCCTTCTCAAGGGCGACGTCTTCACCCCCGACGTTGTCGAGAAGTGGATCGAGTACAAGATGGAAGCCGAGGTCAACC
CGGTCCGCATGCGTCCGGTCCCCCTCGAGTTCGCCCTCTACTACGACATCTAG

Upstream 100 bases:

>100_bases
TGACTCCGGTTGAAGAGGTTATCCGCATACGGACCGGCGAGCGCGGCGAAGACGCACTGTAGCGTCGTACTTTATCTGTT
TTCGAAAGGAGATTGTGTAA

Downstream 100 bases:

>100_bases
TCGAAGGGGCACCATCTGCAGCAAGCGAAAGGCGGGAGCGATCCCGCCTTTCTTTTTTTGCATCGGCGGTTCAGGCTGCC
TCGTTGACTTTCTGCCCCAT

Product: glutamine synthetase, type I

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTPQEVVSFAKENGALMVDYKFMDFVGIWQHVSVPISEFGEDTFEEGQGFDGSSIRGWQPIHASDMILLPDPATAKMDPF
IAVPTLSLICNVFDPITKEDYTRDPRNIARKAEAYLKSTGLGDTAFFGPEAEFFIFDDVRYDSTSNQSFYMVDSVEGAWN
TGREEFPNLGYKPRHKEGYFPVSPTDSQNDLRNEMVMELQKVGIRVECQHHEVASGGQAEIDMRFSSLVDMADQLQWFKY
VIKNVAYRNGKTVTFMPKPLYGDNGSGMHCHMSIWKDGQNLFAGDKYGGLSQMALWYIGGIIKHAKALCALTNPTTNSYK
RLVPGFEAPVNMAYSSRNRSASIRIPMMSTNPKAKRIEYRTPDPSCNGYLAFAAMLMAGLDGIENKIDPGQPLDKDIYGL
SPEELKNIPSAPGSLEEALKALEADHEFLLKGDVFTPDVVEKWIEYKMEAEVNPVRMRPVPLEFALYYDI

Sequences:

>Translated_470_residues
MTPQEVVSFAKENGALMVDYKFMDFVGIWQHVSVPISEFGEDTFEEGQGFDGSSIRGWQPIHASDMILLPDPATAKMDPF
IAVPTLSLICNVFDPITKEDYTRDPRNIARKAEAYLKSTGLGDTAFFGPEAEFFIFDDVRYDSTSNQSFYMVDSVEGAWN
TGREEFPNLGYKPRHKEGYFPVSPTDSQNDLRNEMVMELQKVGIRVECQHHEVASGGQAEIDMRFSSLVDMADQLQWFKY
VIKNVAYRNGKTVTFMPKPLYGDNGSGMHCHMSIWKDGQNLFAGDKYGGLSQMALWYIGGIIKHAKALCALTNPTTNSYK
RLVPGFEAPVNMAYSSRNRSASIRIPMMSTNPKAKRIEYRTPDPSCNGYLAFAAMLMAGLDGIENKIDPGQPLDKDIYGL
SPEELKNIPSAPGSLEEALKALEADHEFLLKGDVFTPDVVEKWIEYKMEAEVNPVRMRPVPLEFALYYDI
>Mature_469_residues
TPQEVVSFAKENGALMVDYKFMDFVGIWQHVSVPISEFGEDTFEEGQGFDGSSIRGWQPIHASDMILLPDPATAKMDPFI
AVPTLSLICNVFDPITKEDYTRDPRNIARKAEAYLKSTGLGDTAFFGPEAEFFIFDDVRYDSTSNQSFYMVDSVEGAWNT
GREEFPNLGYKPRHKEGYFPVSPTDSQNDLRNEMVMELQKVGIRVECQHHEVASGGQAEIDMRFSSLVDMADQLQWFKYV
IKNVAYRNGKTVTFMPKPLYGDNGSGMHCHMSIWKDGQNLFAGDKYGGLSQMALWYIGGIIKHAKALCALTNPTTNSYKR
LVPGFEAPVNMAYSSRNRSASIRIPMMSTNPKAKRIEYRTPDPSCNGYLAFAAMLMAGLDGIENKIDPGQPLDKDIYGLS
PEELKNIPSAPGSLEEALKALEADHEFLLKGDVFTPDVVEKWIEYKMEAEVNPVRMRPVPLEFALYYDI

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=375, Percent_Identity=25.0666666666667, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1790301, Length=471, Percent_Identity=56.0509554140127, Blast_Score=557, Evalue=1e-160,
Organism=Escherichia coli, GI87081870, Length=188, Percent_Identity=30.8510638297872, Blast_Score=93, Evalue=5e-20,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 52796; Mature: 52665

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP ; PS00182 GLNA_ADENYLATION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQEVVSFAKENGALMVDYKFMDFVGIWQHVSVPISEFGEDTFEEGQGFDGSSIRGWQP
CCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCHHHCCCHHHHHCCCCCCCCCCCCCC
IHASDMILLPDPATAKMDPFIAVPTLSLICNVFDPITKEDYTRDPRNIARKAEAYLKSTG
CCCCCEEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
LGDTAFFGPEAEFFIFDDVRYDSTSNQSFYMVDSVEGAWNTGREEFPNLGYKPRHKEGYF
CCCCEEECCCCCEEEEECEEECCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCC
PVSPTDSQNDLRNEMVMELQKVGIRVECQHHEVASGGQAEIDMRFSSLVDMADQLQWFKY
CCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
VIKNVAYRNGKTVTFMPKPLYGDNGSGMHCHMSIWKDGQNLFAGDKYGGLSQMALWYIGG
HHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
IIKHAKALCALTNPTTNSYKRLVPGFEAPVNMAYSSRNRSASIRIPMMSTNPKAKRIEYR
HHHHHHHHEEECCCCCCHHHHHCCCCCCCCHHHHHCCCCCEEEEEEEECCCCCCCEEEEC
TPDPSCNGYLAFAAMLMAGLDGIENKIDPGQPLDKDIYGLSPEELKNIPSAPGSLEEALK
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHCCCCCCCHHHHHHH
ALEADHEFLLKGDVFTPDVVEKWIEYKMEAEVNPVRMRPVPLEFALYYDI
HHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCCEEEEEEECC
>Mature Secondary Structure 
TPQEVVSFAKENGALMVDYKFMDFVGIWQHVSVPISEFGEDTFEEGQGFDGSSIRGWQP
CHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCHHHCCCHHHHHCCCCCCCCCCCCCC
IHASDMILLPDPATAKMDPFIAVPTLSLICNVFDPITKEDYTRDPRNIARKAEAYLKSTG
CCCCCEEEECCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
LGDTAFFGPEAEFFIFDDVRYDSTSNQSFYMVDSVEGAWNTGREEFPNLGYKPRHKEGYF
CCCCEEECCCCCEEEEECEEECCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCCC
PVSPTDSQNDLRNEMVMELQKVGIRVECQHHEVASGGQAEIDMRFSSLVDMADQLQWFKY
CCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
VIKNVAYRNGKTVTFMPKPLYGDNGSGMHCHMSIWKDGQNLFAGDKYGGLSQMALWYIGG
HHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
IIKHAKALCALTNPTTNSYKRLVPGFEAPVNMAYSSRNRSASIRIPMMSTNPKAKRIEYR
HHHHHHHHEEECCCCCCHHHHHCCCCCCCCHHHHHCCCCCEEEEEEEECCCCCCCEEEEC
TPDPSCNGYLAFAAMLMAGLDGIENKIDPGQPLDKDIYGLSPEELKNIPSAPGSLEEALK
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHCCCCCCCHHHHHHH
ALEADHEFLLKGDVFTPDVVEKWIEYKMEAEVNPVRMRPVPLEFALYYDI
HHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7727755; 8905231 [H]