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The map label for this gene is iscR [H]

Identifier: 39996739

GI number: 39996739

Start: 1797963

End: 1798373

Strand: Direct

Name: iscR [H]

Synonym: GSU1639

Alternate gene names: 39996739

Gene position: 1797963-1798373 (Clockwise)

Preceding gene: 39996738

Following gene: 39996740

Centisome position: 47.14

GC content: 59.37

Gene sequence:

>411_bases
ATGGAATTAACCCGGAAGGGTGAATACGCAATTCGCGGCGTCATCTATCTTGCCCAGATTCCACCGGGCACTGTGGCGCT
CATCAGCGAGATCGCCGAGGCGACGGACGTCCCCCAGACGTTTCTTGCCAAGATTCTCCAGAGCTTTGCAAAGATCGGCA
TTGTAAAATCGTTTCGGGGTGCCGGGGGTGGGTTCATCCTGGGGCGTCACCCGTCGCGCATCACCCTGCGCGAAGTGGTG
GAGGCGGTGGAAGGACCGATCATGCCCAACCGTTGCCTCCTTGGAAGTGGCACCTGCGAGCGGGATAATATCTGCGGCGT
TCACCCCGTTTGGCGGAAGGTGCAAGAAAGAGTCGCCGAAACCCTTGACGCGGTGACCCTCGAAGAGCTGGCCGCTACCA
CGAAACTCTGA

Upstream 100 bases:

>100_bases
TCGCAGTAAATAACTTTCGCTTGAGGTTCATTTTCTTTTTGACAGCTCTGATGAGCTCTGTTATAAAAAAGACAAATTCG
GTCTTTTAGGGATTGTTATG

Downstream 100 bases:

>100_bases
AATTTTTTTGCCTGTATACAGGATAAAAATAGTCCTGTATGGTACTCTTAATAAAACCGCGCCCATTCATGGGCGCTTTA
CATGTGCAGCGGCTGCAGCC

Product: Rrf2 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MELTRKGEYAIRGVIYLAQIPPGTVALISEIAEATDVPQTFLAKILQSFAKIGIVKSFRGAGGGFILGRHPSRITLREVV
EAVEGPIMPNRCLLGSGTCERDNICGVHPVWRKVQERVAETLDAVTLEELAATTKL

Sequences:

>Translated_136_residues
MELTRKGEYAIRGVIYLAQIPPGTVALISEIAEATDVPQTFLAKILQSFAKIGIVKSFRGAGGGFILGRHPSRITLREVV
EAVEGPIMPNRCLLGSGTCERDNICGVHPVWRKVQERVAETLDAVTLEELAATTKL
>Mature_136_residues
MELTRKGEYAIRGVIYLAQIPPGTVALISEIAEATDVPQTFLAKILQSFAKIGIVKSFRGAGGGFILGRHPSRITLREVV
EAVEGPIMPNRCLLGSGTCERDNICGVHPVWRKVQERVAETLDAVTLEELAATTKL

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=130, Percent_Identity=31.5384615384615, Blast_Score=70, Evalue=4e-14,
Organism=Escherichia coli, GI1790621, Length=130, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 14742; Mature: 14742

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTRKGEYAIRGVIYLAQIPPGTVALISEIAEATDVPQTFLAKILQSFAKIGIVKSFRG
CCCCCCCCHHHHHEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
AGGGFILGRHPSRITLREVVEAVEGPIMPNRCLLGSGTCERDNICGVHPVWRKVQERVAE
CCCCEEECCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHH
TLDAVTLEELAATTKL
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELTRKGEYAIRGVIYLAQIPPGTVALISEIAEATDVPQTFLAKILQSFAKIGIVKSFRG
CCCCCCCCHHHHHEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
AGGGFILGRHPSRITLREVVEAVEGPIMPNRCLLGSGTCERDNICGVHPVWRKVQERVAE
CCCCEEECCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHH
TLDAVTLEELAATTKL
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA