Click here to switch to the map view.

The map label for this gene is gpm

Identifier: 39996712

GI number: 39996712

Start: 1766005

End: 1766748

Strand: Direct

Name: gpm

Synonym: GSU1612

Alternate gene names: 39996712

Gene position: 1766005-1766748 (Clockwise)

Preceding gene: 39996711

Following gene: 39996722

Centisome position: 46.3

GC content: 60.75

Gene sequence:

>744_bases
ATGAGAACGCTCGTTCTGATTCGTCATGGGGAGAGTGTCTGGAACAGGGAAAACCGTTTTACCGGCTGGACTGACGTGGG
GCTGACCGATAAGGGCGCGGCAGAGGCCCTGCGTGCCGGTCGTACCCTGAAAAACGAGGGGTTTGCCTTTGACGAGGCGT
TCACCTCAGTGCTCAAGCGGGCCATCAAAACCCTCTGGATCGTTTTGGAGGAGATGGATCAGATGTGGATTCCGGAGCAC
CGTCACTGGCGGCTTAATGAACGCCACTACGGCGCGCTCCAGGGACTCAATAAGGCCGAAACTGCCGAAAGGCACGGCAT
GGAACAAGTTCATGTCTGGCGCCGCAGCTATGATATTCCGCCACCGCCCCTGGCCGCCGGCGATCCGCGCAACCCTGCAC
GGGACCCGCGCTATGCGGAGCTTGATCCCGCAGATATCCCCCTGACCGAGTCGCTCAAGGATACCGTAGCCCGTTTCCTT
CCCTACTGGCACGAGACGATTGCGCCCCGCATTCTCGCGGGCCGCCGCCTGCTCATCGCCGCCCATGGCAACAGTCTGCG
GGCCCTGGTGAAGTACCTGGACGGCATCGGGGACGACGCCATTGCCGGTCTGAATATTCCCACCGGCATTCCCCTTGTCT
ATGAGCTGGAAGATGACCTGCACCCCATACGAAGCTATTACCTGGGTGATCCTGACGAGGTTGCCCGGGCCACCCAGTCG
GTGGCGGATCAGGTAAAGAGGTAG

Upstream 100 bases:

>100_bases
AGTTGCTGACCCTTTACATAACACCGGTTATTTATTACTACATGGACCGCATGCAGGGATGGTTCGTCGGGAAACTGCCG
GGCCGCCGGAGGGTCAGCGC

Downstream 100 bases:

>100_bases
GTATGTGTGCGTCAGGGGCTATAGGATGCGATACCCTGGACCCCGCGACACGATAAATCCTTCCGCGGCAAGCTGTTCCA
GGTTTTTCCCCACGATTTCG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRTLVLIRHGESVWNRENRFTGWTDVGLTDKGAAEALRAGRTLKNEGFAFDEAFTSVLKRAIKTLWIVLEEMDQMWIPEH
RHWRLNERHYGALQGLNKAETAERHGMEQVHVWRRSYDIPPPPLAAGDPRNPARDPRYAELDPADIPLTESLKDTVARFL
PYWHETIAPRILAGRRLLIAAHGNSLRALVKYLDGIGDDAIAGLNIPTGIPLVYELEDDLHPIRSYYLGDPDEVARATQS
VADQVKR

Sequences:

>Translated_247_residues
MRTLVLIRHGESVWNRENRFTGWTDVGLTDKGAAEALRAGRTLKNEGFAFDEAFTSVLKRAIKTLWIVLEEMDQMWIPEH
RHWRLNERHYGALQGLNKAETAERHGMEQVHVWRRSYDIPPPPLAAGDPRNPARDPRYAELDPADIPLTESLKDTVARFL
PYWHETIAPRILAGRRLLIAAHGNSLRALVKYLDGIGDDAIAGLNIPTGIPLVYELEDDLHPIRSYYLGDPDEVARATQS
VADQVKR
>Mature_247_residues
MRTLVLIRHGESVWNRENRFTGWTDVGLTDKGAAEALRAGRTLKNEGFAFDEAFTSVLKRAIKTLWIVLEEMDQMWIPEH
RHWRLNERHYGALQGLNKAETAERHGMEQVHVWRRSYDIPPPPLAAGDPRNPARDPRYAELDPADIPLTESLKDTVARFL
PYWHETIAPRILAGRRLLIAAHGNSLRALVKYLDGIGDDAIAGLNIPTGIPLVYELEDDLHPIRSYYLGDPDEVARATQS
VADQVKR

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily

Homologues:

Organism=Homo sapiens, GI50593010, Length=246, Percent_Identity=56.9105691056911, Blast_Score=297, Evalue=7e-81,
Organism=Homo sapiens, GI4505753, Length=246, Percent_Identity=58.130081300813, Blast_Score=280, Evalue=6e-76,
Organism=Homo sapiens, GI71274132, Length=246, Percent_Identity=55.2845528455285, Blast_Score=267, Evalue=7e-72,
Organism=Homo sapiens, GI4502445, Length=248, Percent_Identity=48.7903225806452, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI40353764, Length=248, Percent_Identity=48.7903225806452, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI310129614, Length=160, Percent_Identity=60.625, Blast_Score=187, Evalue=1e-47,
Organism=Escherichia coli, GI1786970, Length=243, Percent_Identity=60.9053497942387, Blast_Score=314, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6322697, Length=247, Percent_Identity=52.6315789473684, Blast_Score=258, Evalue=6e-70,
Organism=Saccharomyces cerevisiae, GI6324516, Length=290, Percent_Identity=30.6896551724138, Blast_Score=135, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6320183, Length=299, Percent_Identity=32.1070234113712, Blast_Score=133, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24646216, Length=247, Percent_Identity=52.2267206477733, Blast_Score=258, Evalue=2e-69,
Organism=Drosophila melanogaster, GI85725270, Length=247, Percent_Identity=53.0364372469636, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI85725272, Length=247, Percent_Identity=53.0364372469636, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24650981, Length=247, Percent_Identity=53.0364372469636, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI28571815, Length=247, Percent_Identity=38.0566801619433, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI28571817, Length=247, Percent_Identity=38.0566801619433, Blast_Score=170, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24648979, Length=247, Percent_Identity=38.4615384615385, Blast_Score=170, Evalue=9e-43,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): GPMA_GEOSL (Q74CR0)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952663.1
- ProteinModelPortal:   Q74CR0
- SMR:   Q74CR0
- GeneID:   2687419
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1612
- NMPDR:   fig|243231.1.peg.1601
- TIGR:   GSU1612
- HOGENOM:   HBG658938
- OMA:   TGWKDPD
- ProtClustDB:   PRK14115
- BioCyc:   GSUL243231:GSU_1612-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0006096
- HAMAP:   MF_01039
- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952
- PANTHER:   PTHR11931
- SMART:   SM00855
- TIGRFAMs:   TIGR01258

Pfam domain/function: PF00300 PGAM

EC number: =5.4.2.1

Molecular weight: Translated: 28069; Mature: 28069

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00175 PG_MUTASE

Important sites: ACT_SITE 9-9 ACT_SITE 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLVLIRHGESVWNRENRFTGWTDVGLTDKGAAEALRAGRTLKNEGFAFDEAFTSVLKR
CCEEEEEECCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
AIKTLWIVLEEMDQMWIPEHRHWRLNERHYGALQGLNKAETAERHGMEQVHVWRRSYDIP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHCHHHHHHHHHHCCCC
PPPLAAGDPRNPARDPRYAELDPADIPLTESLKDTVARFLPYWHETIAPRILAGRRLLIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
AHGNSLRALVKYLDGIGDDAIAGLNIPTGIPLVYELEDDLHPIRSYYLGDPDEVARATQS
ECCCHHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHH
VADQVKR
HHHHHCC
>Mature Secondary Structure
MRTLVLIRHGESVWNRENRFTGWTDVGLTDKGAAEALRAGRTLKNEGFAFDEAFTSVLKR
CCEEEEEECCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
AIKTLWIVLEEMDQMWIPEHRHWRLNERHYGALQGLNKAETAERHGMEQVHVWRRSYDIP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHCHHHHHHHHHHCCCC
PPPLAAGDPRNPARDPRYAELDPADIPLTESLKDTVARFLPYWHETIAPRILAGRRLLIA
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
AHGNSLRALVKYLDGIGDDAIAGLNIPTGIPLVYELEDDLHPIRSYYLGDPDEVARATQS
ECCCHHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHH
VADQVKR
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA