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The map label for this gene is nrnA [H]

Identifier: 39996690

GI number: 39996690

Start: 1743518

End: 1744468

Strand: Direct

Name: nrnA [H]

Synonym: GSU1590

Alternate gene names: 39996690

Gene position: 1743518-1744468 (Clockwise)

Preceding gene: 39996689

Following gene: 39996691

Centisome position: 45.71

GC content: 56.26

Gene sequence:

>951_bases
ATGATTGAAAGCATTCTTCGTGAAATTCGGATTCACCGTAGTTTTTTGATCACCACTCACGAGAATCCTGACGGCGATGC
GGTCGGGTCGTCCCTTGCCCTTGCAGGTTACCTCAAACGCTTGGGCAAGGATGTTACCGTACATTTCTGTGATCCCGTGC
CCGAGTTGTACCGTTTTCTCCCCTTGGCCGACAGTGTCCGACAGGATCTGCCGGATCAGGATTTCGACGTGTGCTTTGTT
CTCGATGTGGGGGAATTTCGCCGAGCCGGCAAACTGGTGAACGAGTGCCGCCGCATCGGCATGTTCATCAATATTGACCA
CCACCTCACCTGTGACCGTTTCGGTACCATCAATTACATAGATTCCGCAGCCGCAGCCAGCGGGGTACTGGTCTACCGCC
TTATCAAGGCCGCCGGTCACGACATCGACTACGATACGGCCCTGGCACTCTATACTTCCATAATCACCGATACCGGTTCT
TTCCGCTACTCGAACGCAAATCCCGAAGCCTTCGCCATTGCGGGTGAGTTGGTCGCCACGGGCATCAATACGTGGTCCAT
TGCCGAGAAACTCTATGAAAGCCAGCCGCGCCAGCGTCTGGAGCTTCTTGCGCTGGCCCTTTCGACGCTTTCTTTCTCCG
CCAACGGGGATTGCGCCTCAATCACCGTGACCCTTGACATGTACGAGAAGGTTGGCGCCTGTGCCGAACTGACCGACGGT
TTCGTCAACTACCCCCGTTCCATCAGGGGGGTGGAAGTCGCGGTTTTCTTCCGCGAGATCCAGCCCCATCTGTTCAAGGT
CGGATTCCGTTCCAAGGGCAAGATCGATGTGTCGAGCCTTGCCGCAGCCTTTGGCGGCGGCGGGCACCACAATGCGGCCG
GTTGTACCCTGACCGGTGATTTGGCCGAAGTCAGAAAGCAGGTTTTCGACCATCTGGAGACTGCTCTCTGA

Upstream 100 bases:

>100_bases
AAATTCGCACCGGAGCTTCACTTCAAATACGACCAGTCAATTGAGTACGGCAACCGGATCGATCAACTGCTGAAAGAAAT
CGAGACTGAGAAAGGTTCCG

Downstream 100 bases:

>100_bases
TTTTCATGGACGGCTTTATCGTCATCGACAAACCGATCGGTCTCACCTCCCATGATGTGGTTGCGAGAGTCAGGCAAACC
CTTCGGCAGAAGAAGGCCGG

Product: DHH domain-containing protein

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MIESILREIRIHRSFLITTHENPDGDAVGSSLALAGYLKRLGKDVTVHFCDPVPELYRFLPLADSVRQDLPDQDFDVCFV
LDVGEFRRAGKLVNECRRIGMFINIDHHLTCDRFGTINYIDSAAAASGVLVYRLIKAAGHDIDYDTALALYTSIITDTGS
FRYSNANPEAFAIAGELVATGINTWSIAEKLYESQPRQRLELLALALSTLSFSANGDCASITVTLDMYEKVGACAELTDG
FVNYPRSIRGVEVAVFFREIQPHLFKVGFRSKGKIDVSSLAAAFGGGGHHNAAGCTLTGDLAEVRKQVFDHLETAL

Sequences:

>Translated_316_residues
MIESILREIRIHRSFLITTHENPDGDAVGSSLALAGYLKRLGKDVTVHFCDPVPELYRFLPLADSVRQDLPDQDFDVCFV
LDVGEFRRAGKLVNECRRIGMFINIDHHLTCDRFGTINYIDSAAAASGVLVYRLIKAAGHDIDYDTALALYTSIITDTGS
FRYSNANPEAFAIAGELVATGINTWSIAEKLYESQPRQRLELLALALSTLSFSANGDCASITVTLDMYEKVGACAELTDG
FVNYPRSIRGVEVAVFFREIQPHLFKVGFRSKGKIDVSSLAAAFGGGGHHNAAGCTLTGDLAEVRKQVFDHLETAL
>Mature_316_residues
MIESILREIRIHRSFLITTHENPDGDAVGSSLALAGYLKRLGKDVTVHFCDPVPELYRFLPLADSVRQDLPDQDFDVCFV
LDVGEFRRAGKLVNECRRIGMFINIDHHLTCDRFGTINYIDSAAAASGVLVYRLIKAAGHDIDYDTALALYTSIITDTGS
FRYSNANPEAFAIAGELVATGINTWSIAEKLYESQPRQRLELLALALSTLSFSANGDCASITVTLDMYEKVGACAELTDG
FVNYPRSIRGVEVAVFFREIQPHLFKVGFRSKGKIDVSSLAAAFGGGGHHNAAGCTLTGDLAEVRKQVFDHLETAL

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 34629; Mature: 34629

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIESILREIRIHRSFLITTHENPDGDAVGSSLALAGYLKRLGKDVTVHFCDPVPELYRFL
CHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
PLADSVRQDLPDQDFDVCFVLDVGEFRRAGKLVNECRRIGMFINIDHHLTCDRFGTINYI
CCHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCEEEEECCCEECCCCCCCHHH
DSAAAASGVLVYRLIKAAGHDIDYDTALALYTSIITDTGSFRYSNANPEAFAIAGELVAT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCEEEHHHHHHH
GINTWSIAEKLYESQPRQRLELLALALSTLSFSANGDCASITVTLDMYEKVGACAELTDG
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEHHHHHCHHHHHHHH
FVNYPRSIRGVEVAVFFREIQPHLFKVGFRSKGKIDVSSLAAAFGGGGHHNAAGCTLTGD
HHCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCEEECH
LAEVRKQVFDHLETAL
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIESILREIRIHRSFLITTHENPDGDAVGSSLALAGYLKRLGKDVTVHFCDPVPELYRFL
CHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHH
PLADSVRQDLPDQDFDVCFVLDVGEFRRAGKLVNECRRIGMFINIDHHLTCDRFGTINYI
CCHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCEEEEECCCEECCCCCCCHHH
DSAAAASGVLVYRLIKAAGHDIDYDTALALYTSIITDTGSFRYSNANPEAFAIAGELVAT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCEEEHHHHHHH
GINTWSIAEKLYESQPRQRLELLALALSTLSFSANGDCASITVTLDMYEKVGACAELTDG
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEHHHHHCHHHHHHHH
FVNYPRSIRGVEVAVFFREIQPHLFKVGFRSKGKIDVSSLAAAFGGGGHHNAAGCTLTGD
HHCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCEEECH
LAEVRKQVFDHLETAL
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]