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The map label for this gene is yacO [H]

Identifier: 39996562

GI number: 39996562

Start: 1602445

End: 1603182

Strand: Direct

Name: yacO [H]

Synonym: GSU1462

Alternate gene names: 39996562

Gene position: 1602445-1603182 (Clockwise)

Preceding gene: 39996561

Following gene: 39996563

Centisome position: 42.01

GC content: 60.57

Gene sequence:

>738_bases
GTGAAAGAAGAAATTCTGTACGGAATCAACAGTGTGATGGAGGCCCTGCGCGGATCGCGGAGGGCCTTCGAACTTTTCGT
TTCCCGGGAGACCCACGACCGGCGCACGGAGAAACTGCTCGCGTTTGCCGCTGAAAGGGGGGTGCCGGTCCGAACGCGCG
ACAAGCGCGACCTTGCCCGTCTCTGCGGTACCGACCACCATCAGGGTGTTGCCCTGCGAGTCGAAGGCTTTGCGTACGCC
GCTCTTGAAGACATCATCGCCTCATGGCAATCCTCCGGGGAGCCGGGACTCATTCTTGTTTTGGATGGAATACAGGACCC
GCACAATCTGGGAGCGCTCATCCGAAGCGCCGCCTGTGCCGGAGCCCATGGCGTCATTATCCCCAGAGACCGGGCCGCCG
GCGTAACCGCTTCGGTTGAAAAGATTTCTGCCGGCGCAACAGAGACGATTCCGGTGGCCCAGGTGACGAATGTCGTCCAG
GCGCTGGAAACTCTCAAAGAAGAAGGGTTCTGGGCATTCGGCACTGCCGACAGTGCGGCCTCGTCACTCTATAGTCATGA
CTTGACCGGCAATGTCGTCATCGTGATCGGCGGTGAAGGGGAGGGGGTCAGGCCCCTCGTGCGGAAGAAGTGCGATTTCC
TCGTGGCTATCCCCCTGAAAGGAGGGGTTAGCTCGCTCAATGCCTCAGTGGCGGGGGGCGTTGTCCTCTTCGAGGTGGTG
CGACAGCGTCTGTCTTGA

Upstream 100 bases:

>100_bases
GTTATCGGCCGCCCGATCGGCGACGCCCCTGACCCGGCCGGCGCAGCCGAAATGATTCTCGACGAGATCATGGCCGGCTG
AGGGAAAAAGGAACCACAGC

Downstream 100 bases:

>100_bases
CGCTGTGTACGCGTGTCTGAATGGGGAAAGGTTTTGTGTTAAATTGTGTCAAATAGCTTGTGAATAAGGTTGTTGATAAA
AAAGGGGCTCCCCATCGGGA

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MKEEILYGINSVMEALRGSRRAFELFVSRETHDRRTEKLLAFAAERGVPVRTRDKRDLARLCGTDHHQGVALRVEGFAYA
ALEDIIASWQSSGEPGLILVLDGIQDPHNLGALIRSAACAGAHGVIIPRDRAAGVTASVEKISAGATETIPVAQVTNVVQ
ALETLKEEGFWAFGTADSAASSLYSHDLTGNVVIVIGGEGEGVRPLVRKKCDFLVAIPLKGGVSSLNASVAGGVVLFEVV
RQRLS

Sequences:

>Translated_245_residues
MKEEILYGINSVMEALRGSRRAFELFVSRETHDRRTEKLLAFAAERGVPVRTRDKRDLARLCGTDHHQGVALRVEGFAYA
ALEDIIASWQSSGEPGLILVLDGIQDPHNLGALIRSAACAGAHGVIIPRDRAAGVTASVEKISAGATETIPVAQVTNVVQ
ALETLKEEGFWAFGTADSAASSLYSHDLTGNVVIVIGGEGEGVRPLVRKKCDFLVAIPLKGGVSSLNASVAGGVVLFEVV
RQRLS
>Mature_245_residues
MKEEILYGINSVMEALRGSRRAFELFVSRETHDRRTEKLLAFAAERGVPVRTRDKRDLARLCGTDHHQGVALRVEGFAYA
ALEDIIASWQSSGEPGLILVLDGIQDPHNLGALIRSAACAGAHGVIIPRDRAAGVTASVEKISAGATETIPVAQVTNVVQ
ALETLKEEGFWAFGTADSAASSLYSHDLTGNVVIVIGGEGEGVRPLVRKKCDFLVAIPLKGGVSSLNASVAGGVVLFEVV
RQRLS

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=266, Percent_Identity=31.203007518797, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1790623, Length=244, Percent_Identity=42.2131147540984, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1788935, Length=246, Percent_Identity=30.0813008130081, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1790083, Length=153, Percent_Identity=30.0653594771242, Blast_Score=64, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17555908, Length=261, Percent_Identity=28.3524904214559, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324775, Length=294, Percent_Identity=30.6122448979592, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26083; Mature: 26083

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEEILYGINSVMEALRGSRRAFELFVSRETHDRRTEKLLAFAAERGVPVRTRDKRDLAR
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LCGTDHHQGVALRVEGFAYAALEDIIASWQSSGEPGLILVLDGIQDPHNLGALIRSAACA
HHCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
GAHGVIIPRDRAAGVTASVEKISAGATETIPVAQVTNVVQALETLKEEGFWAFGTADSAA
CCCCEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHH
SSLYSHDLTGNVVIVIGGEGEGVRPLVRKKCDFLVAIPLKGGVSSLNASVAGGVVLFEVV
HHHHHCCCCCCEEEEECCCCCCCCHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
RQRLS
HHHCC
>Mature Secondary Structure
MKEEILYGINSVMEALRGSRRAFELFVSRETHDRRTEKLLAFAAERGVPVRTRDKRDLAR
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LCGTDHHQGVALRVEGFAYAALEDIIASWQSSGEPGLILVLDGIQDPHNLGALIRSAACA
HHCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
GAHGVIIPRDRAAGVTASVEKISAGATETIPVAQVTNVVQALETLKEEGFWAFGTADSAA
CCCCEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHH
SSLYSHDLTGNVVIVIGGEGEGVRPLVRKKCDFLVAIPLKGGVSSLNASVAGGVVLFEVV
HHHHHCCCCCCEEEEECCCCCCCCHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
RQRLS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]