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The map label for this gene is appC [H]

Identifier: 39996535

GI number: 39996535

Start: 1573971

End: 1574819

Strand: Direct

Name: appC [H]

Synonym: GSU1435

Alternate gene names: 39996535

Gene position: 1573971-1574819 (Clockwise)

Preceding gene: 39996534

Following gene: 39996536

Centisome position: 41.27

GC content: 63.02

Gene sequence:

>849_bases
ATGGCCTACCGCGACAGCTGGTTCCATACGGTCTTCTGGAAACGTTTCCGGCGCAACCGTTTCGCCCTGGCCGGCGGCGT
GGTTGTGGTGGTGCTCTTTGCCATCTCGTTCCTGGCTCCCTACATCGCCCCCTGGGACCCGGACGCCATCGACGCCTACC
GCGTTCTGCTCCCGCCGTCGGCCGAACACTGGTTCGGGACCGACGAACTGGGGCGGGACGTCTTTACCCGTGTCATCTAC
GGAGCCAGGATCTCGCTCAAGGTGGGATTCGTATCAGTAGGCATCGCCGTGGTTATCGGCACGGTGCTCGGTCTCGTCTC
CGGATTCTACGGCGGGCTTGTCGATACGATTATCATGCGGTTCGTGGACATCATGCTCTGCTTCCCCACGTTTTTTCTCA
TCCTCGCGGTGATCGCCTTTCTGGAGCCGTCTATCTGGTACATTATGGCCATCATCGGCCTCACGGGCTGGATGGGAGTG
GCCCGGCTCGTGCGGGCCGAGGTCCTGTCGCTGCGGGAGCGTGATTTCGTGCTGGCTGCCCGCGCCCTCGGCGCATCGGA
TGTGCGGATACTGCTCCGCCATGTCCTGCCAAACGCCGTATCGCCGGTCCTGGTGTCCGCCACCCTTGGTGTGGCCGGCG
CAATTCTCACCGAATCGGCTCTGTCTTTTCTCGGCATCGGGGTCCAGCCCCCCACGCCGAGCTGGGGTAACATCCTCACC
TCCGGCAAGGACTACATCGAGTTCGCCTGGTGGCTTTCGCTGTTCCCCGGCGGAGCCATCCTGGTGACCGTTCTGGCCTA
CAATCTGTTGGGCGAGGGAATCAGGGACGCCCTTGACCCGCGGGTCTGA

Upstream 100 bases:

>100_bases
TCTCGTCATCGGCGCGTTCCTTACGCTCATCGGTAACCTGCTGGCCGATGTCTGCTATGCCATGGCCGATCCGCGCATCC
GGCACGGAAGGGGGTAGGGG

Downstream 100 bases:

>100_bases
TCTTTTACACAAGCAAAGGTGGTTGCATGACAACATACTATTCACCGGCCGCCGAGCTCGAAGGCGAGCTCGTCATTGAT
AAGGCCGATTTCGTCATCGC

Product: peptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MAYRDSWFHTVFWKRFRRNRFALAGGVVVVVLFAISFLAPYIAPWDPDAIDAYRVLLPPSAEHWFGTDELGRDVFTRVIY
GARISLKVGFVSVGIAVVIGTVLGLVSGFYGGLVDTIIMRFVDIMLCFPTFFLILAVIAFLEPSIWYIMAIIGLTGWMGV
ARLVRAEVLSLRERDFVLAARALGASDVRILLRHVLPNAVSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNILT
SGKDYIEFAWWLSLFPGGAILVTVLAYNLLGEGIRDALDPRV

Sequences:

>Translated_282_residues
MAYRDSWFHTVFWKRFRRNRFALAGGVVVVVLFAISFLAPYIAPWDPDAIDAYRVLLPPSAEHWFGTDELGRDVFTRVIY
GARISLKVGFVSVGIAVVIGTVLGLVSGFYGGLVDTIIMRFVDIMLCFPTFFLILAVIAFLEPSIWYIMAIIGLTGWMGV
ARLVRAEVLSLRERDFVLAARALGASDVRILLRHVLPNAVSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNILT
SGKDYIEFAWWLSLFPGGAILVTVLAYNLLGEGIRDALDPRV
>Mature_281_residues
AYRDSWFHTVFWKRFRRNRFALAGGVVVVVLFAISFLAPYIAPWDPDAIDAYRVLLPPSAEHWFGTDELGRDVFTRVIYG
ARISLKVGFVSVGIAVVIGTVLGLVSGFYGGLVDTIIMRFVDIMLCFPTFFLILAVIAFLEPSIWYIMAIIGLTGWMGVA
RLVRAEVLSLRERDFVLAARALGASDVRILLRHVLPNAVSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNILTS
GKDYIEFAWWLSLFPGGAILVTVLAYNLLGEGIRDALDPRV

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=280, Percent_Identity=43.2142857142857, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1787760, Length=266, Percent_Identity=41.7293233082707, Blast_Score=224, Evalue=5e-60,
Organism=Escherichia coli, GI1789964, Length=277, Percent_Identity=45.1263537906137, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1787498, Length=270, Percent_Identity=41.8518518518518, Blast_Score=191, Evalue=3e-50,
Organism=Escherichia coli, GI1789889, Length=239, Percent_Identity=38.9121338912134, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1788505, Length=225, Percent_Identity=40, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787549, Length=272, Percent_Identity=33.4558823529412, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30891; Mature: 30760

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYRDSWFHTVFWKRFRRNRFALAGGVVVVVLFAISFLAPYIAPWDPDAIDAYRVLLPPS
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEECCC
AEHWFGTDELGRDVFTRVIYGARISLKVGFVSVGIAVVIGTVLGLVSGFYGGLVDTIIMR
CCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDIMLCFPTFFLILAVIAFLEPSIWYIMAIIGLTGWMGVARLVRAEVLSLRERDFVLAA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALGASDVRILLRHVLPNAVSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNILT
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHC
SGKDYIEFAWWLSLFPGGAILVTVLAYNLLGEGIRDALDPRV
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AYRDSWFHTVFWKRFRRNRFALAGGVVVVVLFAISFLAPYIAPWDPDAIDAYRVLLPPS
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHEEECCC
AEHWFGTDELGRDVFTRVIYGARISLKVGFVSVGIAVVIGTVLGLVSGFYGGLVDTIIMR
CCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDIMLCFPTFFLILAVIAFLEPSIWYIMAIIGLTGWMGVARLVRAEVLSLRERDFVLAA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RALGASDVRILLRHVLPNAVSPVLVSATLGVAGAILTESALSFLGIGVQPPTPSWGNILT
HHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHC
SGKDYIEFAWWLSLFPGGAILVTVLAYNLLGEGIRDALDPRV
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]